12 completed, 5 recruiting, 4 unknown, 3 not yet recruiting. 21 Not applicable, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 21 | Completed 10, Recruiting 5, Not yet recruiting 3, Unknown 3 |
| Phase 4 | 2 | Completed 2 |
Follow this condition Literature Review of Heat Exposure trials Research Report on Heat Exposure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Progressive Heat Exposure and Physiological Strain Constant Heat Exposure, Progressively Increasing Heat Exposure - Body Temperature Changes, Heat Stress | Not applicable | Not yet recruiting | University of Ottawa | 14 | 2026-10-01 | 2026-09-29 |
| Effects of Creatine and Heat Exposure on Exercise Performance and Body Water Distribution Creatine Monohydrate, Maltodextrin (Placebo) - Heat Exposure, Exercise Performance | Not applicable | Not yet recruiting | University of Windsor | 25 | 2026-07-30 | 2026-05-18 |
| Consecutive Occupational Heat Exposure With and Without Overnight Cooling Simulated occupational heat exposure with recovery at recommended indoor temperature limit, Simulated occupational heat exposure with recovery in an overheated indoor environment - Body Temperature Changes, Heat Stress | Not applicable | Recruiting | University of Ottawa | 10 | 2026-06-24 | 2026-10-05 |
| Working in the Heat at Simulated Altitude: Effects of Normobaric Hypoxia on Physiological Strain Simulated Occupational heat exposure under normoxic conditions, Simulated Occupational heat exposure under hypoxic conditions - Body Temperature Changes, Heat Stress | Not applicable | Recruiting | University of Ottawa | 20 | 2026-06-17 | 2026-07-14 |
| Identifying the Limits of Survivability in Heat-exposed Older Females Humidity-Ramp Protocol, Above-inflection fixed-condition exposure (5%), Below-inflection fixed-condition exposure (5%) - Heat Stress, Temperature Change, Body | Not applicable | Completed | University of Ottawa | 12 | 2025-07-16 | 2026-06-11 |
| Beat the Heat Boston Air Conditioner, Electricity subsidy - Hot Weather; Adverse Effect, Heat Effect | Not applicable | Recruiting | Harvard School of Public Health (HSPH) | 100 | 2025-05-19 | 2026-01-22 |
| Assessing the Effectiveness of Heat Adaptation Digital Messages From Primary Care Providers to Their Patients on the Change in Behaviour for Heatwave-related Preparedness Heat adaptation digital messaging, Non-heat-related digital messaging - Heathly Subjects, Primary Health Care | Not applicable | Recruiting | Hopital Montfort | 20000 | 2025-04-01 | 2026-09-18 |
| Postexercise Hot-Water Immersion on Exercise Performance in Hypoxia Post-Exercise Hot Water Immersion, Control Group - Heat Exposure, Exercise Training | Not applicable | Not yet recruiting | Nipissing University | 20 | 2024-11-01 | 2024-11-04 |
| Mechanisms Underlying Hypoxic, Heat and Cross-tolerance Adaptation in Women Heat acclimation and exercise training, Thermo-neutral exercise training group - Heat Exposure, Exercise Training | Not applicable | Unknown | Jozef Stefan Institute | 30 | 2024-10-01 | 2024-08-28 |
| Initial Stay Times and Heat Mitigation Controls for Uncompensable Occupational Heat Stress - Part III Simulated work in the heat with no cooling during rest breaks, Simulated work in the heat with partial cooling during rest breaks, Simulated work in the heat with full cooling during rest breaks - Body Temperature Changes, Heat Stress | Not applicable | Completed | University of Ottawa | 23 | 2024-09-27 | 2025-06-17 |
| Heat Acclimation in Females Heat exposure, Control group - Heat Exposure, Blood Volume | Not applicable | Completed | Trinity Western University | 15 | 2024-09-01 | 2026-10-01 |
| Preparing for Heat Waves - Enhancing Human Thermophysiological Resilience Heat acclimation - Body Temperature Changes, Heat Exposure | Not applicable | Unknown | Maastricht University Medical Center | 12 | 2024-05-01 | 2024-04-29 |
| Safe Indoor Temperature Limit for Fans Temperature Ramp Protocol - Heat Exposure, Healthy | Not applicable | Completed | Lakehead University | 10 | 2024-01-20 | 2024-09-19 |
| Validity of Humidity Ramp Protocols for Identifying Limits of Survivability in Heat-exposed Persons Humidity-ramp protocol, Above-inflection fixed-condition exposure, Below-inflection fixed-condition exposure - Heat Stress, Heat Exposure | Not applicable | Completed | University of Ottawa | 12 | 2023-07-14 | 2023-11-29 |
| Effect of Water Biking in Hot Versus Neutral Water for Heat Acclimatation Water Biking in hot water condition, Water Biking in neutral water condition - Healthy, Heat Exposure | Not applicable | Completed | University Hospital, Montpellier | 24 | 2023-02-08 | 2026-06-12 |
| Temperature Recording in Lungs of Volunteers With and Without Pulmonary Diseases Temperature-measurement in lungs under sauna bath - Temperature Change, Body, Bronchiectasis | Unknown | Chronic Obstructive Pulmonary Disease Trial Network, Denmark | 10 | 2022-09-01 | 2023-09-01 | |
| The Influence of Capsaicin Gel During Exercise Within the Heat Capsaicin, Control Gel, Exercise - Acute Exercise, Heat Exposure | Phase 4 | Completed | University of Nebraska | 12 | 2022-05-25 | 2024-03-15 |
| The Influence of Menthol Gel During Exercise With Heat Menthol Gel, Control Gel - Acute Exercise, Heat Exposure | Phase 4 | Completed | University of Nebraska | 12 | 2022-05-01 | 2024-04-24 |
| Hot Water Immersion as a Heat Acclimation Strategy in Older Adults Heat acclimation - Hyperthermia, Heat Exposure | Not applicable | Completed | University of Ottawa | 12 | 2022-04-29 | 2024-07-11 |
| Home-based Heat Therapy for Type 2 Diabetes Thermoneutral water, Hot water - Diabetes Mellitus, Type 2, Heat Exposure | Not applicable | Recruiting | Montreal Heart Institute | 44 | 2022-02-18 | 2026-05-12 |
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Heat Stress Disorders (11) · Body Temperature Changes (8) · Motor Activity (7) · Hyperthermia (6) · Occupational Stress (4) · Altitude Sickness (2) · Heat Exhaustion (2) · Heat Stroke (2) · Bronchiectasis (1) · Diabetes Mellitus, Type 2 (1) · Hypernatremia (1) · Hypoxia (1) · Labor Pain (1) · Risk Reduction Behavior (1) · Sunstroke (1)
Wounds and Injuries (11) · Pathological Conditions, Signs and Symptoms (10) · Signs and Symptoms (10) · Behavior (8) · Behavioral Symptoms (4) · Occupational Diseases (4) · Stress, Psychological (4) · Respiratory Tract Diseases (3) · Metabolic Diseases (2) · Nutritional and Metabolic Diseases (2) · Respiration Disorders (2) · Body Temperature Changes (1) · Bronchial Diseases (1) · Chemically-Induced Disorders (1) · Diabetes Mellitus (1)
Exercise (3) · Control Groups (2) · Capsaicin (1) · Creatine (1) · Salvage Therapy (1) · maltodextrin (1)
University of Ottawa (7) · University of Nebraska (2) · Chronic Obstructive Pulmonary Disease Trial Network, Denmark (1) · Harvard School of Public Health (HSPH) (1) · Hopital Montfort (1) · Istanbul Demiroglu Bilim University (1) · Johns Hopkins University (1) · Jozef Stefan Institute (1) · Lakehead University (1) · Maastricht University Medical Center (1) · Montreal Heart Institute (1) · Nipissing University (1) · Trinity Western University (1) · University Hospital, Montpellier (1) · University School of Physical Education, Krakow, Poland (1)
Canada (12) · United States (4) · Denmark (1) · France (1) · Pakistan (1) · Poland (1) · Slovenia (1) · Turkey (Türkiye) (1)
Glen P Kenny, PhD (3) · Douglas J Casa, PhD (1) · Dustin R Slivka, PHD (1) · Dustin R Slivka, PhD (1) · Geoffrey L Hartley, PhD (1) · Glen P Kenny, PhD. (1) · Guy Plasqui (1) · Hannah Pallubinsky, Dr. (1) · Junaid A Razzak, MD PhD (1) · Marcin Maciejczyk, Prof. dr (1) · Nicholas Ravanelli, PhD (1) · Robert D Meade, PhD, MPH (1) · Tadej Debevec, PhD (1)
PMID 35101860, PMID 39820413, PMID 40663144, PMID 41549363, PMID 42406578
P20TW013028 (1)