4 recruiting, 3 completed, 3 unknown, 1 terminated. 5 Phase 1, 4 Phase 2, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 1, Recruiting 1, Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 4 | Recruiting 2, Terminated 1, Unknown 1 |
| Not applicable | 1 | Unknown 1 |
Follow GVHD,Acute: new trials by email Literature Review of GVHD,Acute trials Research Report on GVHD,Acute
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Novel First-line Therapies for Grade II Acute GVHD(Graft-versus-host Disease ) Ruxolitinib, Corticosteroids - GVHD,Acute, Stem Cell Transplant Complications | Phase 2 | Recruiting | Daihong Liu | 168 | 2025-06-01 | 2026-01-14 |
| Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant ATG Combined with Tacrolimus and Mini Methotrexate - GVHD,Acute, Acute Leukemia | Phase 2 | Recruiting | University of Alabama at Birmingham | 29 | 2025-04-15 | 2026-10-09 |
| Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT) TRX103 - Hematologic Malignancy, GvHD | Phase 1 | Recruiting | Tr1X, Inc. | 36 | 2024-04-08 | 2025-04-15 |
| Safety and Efficacy Study of hAESCs Therapy for aGVHD Human Amniotic Epithelial Stem Cell Injection - GVHD,Acute, aGVHD | Phase 1 | Completed | Shanghai iCELL Biotechnology Co., Ltd, Shanghai, China | 10 | 2024-02-19 | 2026-10-15 |
| Wharton Jelly Mesenchymal Stromal Cells as GVHD Prophylaxis WJ-MSC infusion - Allogeneic Disease, GVHD,Acute | Phase 1 | Unknown | Central Hospital, Nancy, France | 12 | 2023-09-01 | 2023-05-11 |
| Mesenchymal Stem Cells (MSCs) for Steroid Refractory Acute GVHD (SR-aGVHD) OSSM-001 - GVHD,Acute | Phase 1 | Withdrawn | Ossium Health, Inc. | 2023-06-05 | 2022-12-23 | |
| CXCL9 and EASIX for Prediction of Acute Graft Versus Host Disease blood sample - GVHD,Acute | Recruiting | Henry Ford Health System | 100 | 2023-05-10 | 2026-05-01 | |
| MAP-guided Preemptive Therapy of aGvHD Methylprednisolone - GVHD,Acute, Stem Cell Transplant Complications | Phase 2 | Unknown | Sichuan University | 56 | 2022-05-01 | 2022-05-10 |
| Physiotherapy and Therapeutic Exercise Program in Graft-versus-host Disease (GvHD) Physical exercise - GVHD,Acute, GVHD, Chronic | Not applicable | Unknown | University of Salamanca | 12 | 2022-05-01 | 2022-06-02 |
| A Study of IBI377 in Combination With Corticosteroids for the Treatment of First-Line Acute Graft-Versus-Host Disease Itacitinib, Prednisone, Methylprednisolone - GVHD,Acute | Phase 1 / Phase 2 | Terminated | Innovent Biologics (Suzhou) Co. Ltd. | 1 | 2020-06-18 | 2020-10-29 |
| Role of aGVHD Biomarkers on aGVHD Risks aGVHD biomarker - GVHD,Acute, Biomarker | Completed | Chinese PLA General Hospital | 500 | 2019-02-01 | 2026-05-05 | |
| Analysis of Intestinal Defensin Expression in Acute GVHD GVHD,Acute, Ulcerative Colitis | Completed | University of Freiburg | 80 | 2018-09-01 | 2024-12-18 |
Bronchiolitis Obliterans Syndrome (2) · Myelodysplastic Syndromes (2) · Colitis, Ulcerative (1) · Crohn Disease (1) · Graft vs Host Disease (1) · Hematologic Neoplasms (1) · Leukemia (1) · Leukemia, Myelomonocytic, Chronic (1) · Myeloproliferative Disorders (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (1)
Bone Marrow Diseases (2) · Bronchial Diseases (2) · Bronchiolitis (2) · Bronchiolitis Obliterans (2) · Bronchitis (2) · Hematologic Diseases (2) · Hemic and Lymphatic Diseases (2) · Immune System Diseases (2) · Lung Diseases (2) · Lung Diseases, Obstructive (2) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Organizing Pneumonia (2) · Respiratory Tract Diseases (2) · Chronic Disease (1)
Methylprednisolone (2) · Adrenal Cortex Hormones (1) · Blood Specimen Collection (1) · Exercise (1) · Prednisone (1) · Tacrolimus (1) · itacitinib (1) · ruxolitinib (1)
Central Hospital, Nancy, France (1) · Chinese PLA General Hospital (1) · Daihong Liu (1) · Henry Ford Health System (1) · Innovent Biologics (Suzhou) Co. Ltd. (1) · Ossium Health, Inc. (1) · Shanghai iCELL Biotechnology Co., Ltd, Shanghai, China (1) · Sichuan University (1) · Tr1X, Inc. (1) · University of Alabama at Birmingham (1) · University of Freiburg (1) · University of Salamanca (1)
China (5) · United States (3) · Germany (1) · Spain (1)
Daihong Liu (1) · Maria Grazia Roncarolo, MD (1) · Robert Zeiser, Prof. Dr. (1) · Sagar Munjal (1) · Xiaojun Huang, M.D., PhD (1)
2023 (1)