6 completed, 5 unknown, 4 recruiting, 1 not yet recruiting. 5 Phase 2, 2 Not applicable, 2 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 2, Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Not applicable | 2 | Completed 1, Terminated 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Glomerular Disease: new trials by email Literature Review of Glomerular Disease trials Research Report on Glomerular Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety Study of HS-10542 for IgA Nephropathy HS-10542 High Dose, HS-10542 Low Dose, Placebo - IgAN, Immunoglobulin A Nephropathy (IgAN) | Phase 2 | Not yet recruiting | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 90 | 2026-03-17 | 2026-03-16 |
| Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy. zigakibart - Kidney Diseases, Kidney Diseases, Chronic | Phase 3 | Recruiting | Novartis Pharmaceuticals | 220 | 2025-07-28 | 2026-08-17 |
| Podocyts Integrity in Glomerular Diseases Histopathological examination of tru-cut needle biopsy - Glomerular Disease | Unknown | Assiut University | 50 | 2023-07-01 | 2023-06-12 | |
| Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome. Interview - Fluid Overload, Glomerulosclerosis, Focal Segmental | Recruiting | University of Michigan | 150 | 2022-04-18 | 2025-12-22 | |
| Study of Safety and Efficacy of ANG-3070 in Chronic Kidney Disease ANG-3070, Placebo - Glomerular Disease, Proteinuria | Phase 2 | Unknown | Angion Biomedica Corp | 100 | 2021-12-24 | 2022-03-23 |
| Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell Anemia iohexol GFR - Sickle Cell Disease, Renal Disease | Completed | University of Alabama at Birmingham | 120 | 2021-05-12 | 2025-09-18 | |
| Safety and Efficacy Study of VIS649 for IgA Nephropathy Dose-Placebo, Low Dose-VIS649, Medium Dose-VIS649 - Immunoglobulin A Nephropathy, Glomerular Disease | Phase 2 | Completed | Otsuka Pharmaceutical Development & Commercialization, Inc. | 155 | 2020-07-20 | 2026-04-24 |
| Effect of Moderate Caloric Restriction on Glomerular Growth After Kidney Transplantation caloric intake reduction - Kidney Transplant; Complications, Glomerular Disease | Not applicable | Terminated | University of Michigan | 1 | 2019-08-22 | 2023-02-08 |
| The Impact of Glomerular Disorders on Bone Quality and Strength Dual-energy X-ray absorptiometry, High Resolution Peripheral Quantitative Computed Tomography (HR-pQCT), Blood draw and Urine collection - Glomerular Disease, Bone Diseases, Metabolic | Unknown | Columbia University | 270 | 2019-06-14 | 2024-07-01 | |
| KOrea Renal Biobank NEtwoRk System TOward NExt-generation Analysis Kidney Biopsy - Glomerular Disease, Minimal Change Disease | Recruiting | Seoul National University Hospital | 3000 | 2019-05-01 | 2020-02-12 | |
| Effect of Glucocorticoids on Inflammation and Bone Metabolism in Patients With Glomerular Disease Methylprednisolone, prednisone - Glomerular Disease | Unknown | Medical University of Lodz | 40 | 2018-10-01 | 2021-08-03 | |
| Low Dose Steroids in the Treatment of Nephrotic Syndrome Relapse prednisone 60 mg/meter square Body Surface Area, prednisone 45 mg, prednisone 30 mg - Glomerular Disease | Phase 4 | Unknown | Rabin Medical Center | 100 | 2014-09-01 | 2014-08-15 |
| Vitamin D Supplementation in Glomerular Disease Cholecalciferol, 2000 or 4000 IUs by mouth daily for 12 weeks - Glomerular Disease | Not applicable | Completed | Children's Hospital of Philadelphia | 32 | 2013-04-01 | 2019-08-12 |
| Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy Rituximab Infusion, Oral Cyclosporine - Nephrotic Syndrome, Proteinuria | Phase 2 | Recruiting | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 30 | 2010-12-22 | 2026-10-26 |
| TRK-100STP Clinical Study - Chronic Renal Failure (Primary Glomerular Disease/Nephrosclerosis) TRK-100STP high dose, TRK-100STP low dose, Placebo - Chronic Renal Failure, Glomerular Disease | Phase 2 / Phase 3 | Completed | Toray Industries, Inc | 892 | 2010-03-01 | 2015-02-04 |
| Kidney Disease Biomarkers Kidney Disease, Glomerular Disease | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 25 | 2005-11-10 | 2019-12-17 | |
| Pathogenesis of Glomerulosclerosis Glomerular Disease | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 537 | 1996-04-16 | 2026-11-12 |
Kidney Diseases (7) · Glomerulonephritis, IGA (5) · Glomerulonephritis, Membranous (4) · Glomerulosclerosis, Focal Segmental (4) · Nephrosis, Lipoid (4) · Proteinuria (4) · Autoimmune Diseases (3) · Nephrotic Syndrome (3) · Glomerulonephritis (2) · Immune System Diseases (2) · Nephritis (2) · Renal Insufficiency, Chronic (2) · Anemia, Sickle Cell (1) · Bone Diseases, Metabolic (1) · Diabetic Nephropathies (1)
Female Urogenital Diseases (11) · Female Urogenital Diseases and Pregnancy Complications (11) · Male Urogenital Diseases (11) · Urogenital Diseases (11) · Urologic Diseases (11) · Pathological Conditions, Signs and Symptoms (8) · Glomerulonephritis (6) · Nephritis (6) · Signs and Symptoms (6) · Immune System Diseases (5) · Kidney Diseases (5) · Nephrosis (5) · Autoimmune Diseases (4) · Pathologic Processes (4) · Urination Disorders (4)
Prednisone (2) · Absorptiometry, Photon (1) · Blood Specimen Collection (1) · Bone Density (1) · Cholecalciferol (1) · Cyclosporine (1) · Interviews as Topic (1) · Methylprednisolone (1) · Surveys and Questionnaires (1) · Urine Specimen Collection (1) · Vitamin D (1)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (3) · University of Michigan (2) · Angion Biomedica Corp (1) · Assiut University (1) · Children's Hospital of Philadelphia (1) · Columbia University (1) · Jiangsu Hansoh Pharmaceutical Co., Ltd. (1) · Medical University of Lodz (1) · Novartis Pharmaceuticals (1) · Otsuka Pharmaceutical Development & Commercialization, Inc. (1) · Rabin Medical Center (1) · Seoul National University Hospital (1) · Toray Industries, Inc (1) · University of Alabama at Birmingham (1)
United States (11) · South Korea (4) · Australia (3) · Malaysia (3) · Taiwan (3) · Canada (2) · China (2) · Hong Kong (2) · Japan (2) · Spain (2) · Thailand (2) · Argentina (1) · Georgia (1) · India (1) · Israel (1)
Abhijit Naik, MD (1) · Amit Dagan, Doctor (1) · Anirban Ganguli, M.D. (1) · Asher Schachter, M.D. (1) · Dong Ki Kim, MD, PhD (1) · Eloise Salmon, M.D. (1) · Jeffrey B Kopp, M.D. (1) · Jeffrey Lebensburger, DO, MSPH (1) · John Neylan, MD (1) · John Peipert, Ph.D. (1) · Meryl A Waldman, M.D. (1) · Michelle Denburg, MD, MSCE (1) · Thomas L. Nickolas, MD (1)
PMID 25233856, PMID 32842999, PMID 35224730, PMID 36821613, PMID 37916620, PMID 38299639, PMID 39171624, PMID 42275148
2019 (1), K23DK093556 (1), P30DK089503 (1), R01DK119266 (1), R01HL153386 (1)