7 unknown, 6 completed, 4 recruiting, 4 terminated. 11 Phase 2, 4 Early Phase 1, 4 Phase 1, 2 Not applicable, 1 Phase 3.
Follow Glioma of Brain: new trials by email Literature Review of Glioma of Brain trials Research Report on Glioma of Brain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Patient Voice in the Treatment of Low-grade Gliomas: Use of Patient-reported Outcomes, Vorasidenib and Radiotherapy Compared Vorasidenib, Radiotherapy, active surveillance - Glioma, Glioma of Brain | Recruiting | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 90 | 2025-04-23 | 2026-04-23 | |
| Azoles Targeting Recurrent High Grade Gliomas Ketoconazole (KCZ), Posaconazole (PCZ) - Brain Tumor, Recurrent, Cancer, Advanced | Early Phase 1 | Not yet recruiting | University Health Network, Toronto | 30 | 2024-06-01 | 2024-03-08 |
| Early Temozolomide in Patients With High-Grade Gliomas in Rehabilitation Temozolomide - Glioma of Brain | Early Phase 1 | Withdrawn | University of Rochester | 2021-09-01 | 2021-04-09 | |
| Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases Dynamic Contrast-Enhanced Magnetic Resonance Imaging, Bevacizumab Injection - Brain Metastases, Glioma of Brain | Not applicable | Terminated | University of Southern California | 15 | 2021-04-13 | 2025-08-05 |
| A Large-scale Research for Immunotherapy of Glioblastoma With Autologous Heat Shock Protein gp96 gp96, Temozolomide, radiotherapy - Glioma of Brain | Phase 2 | Unknown | Cure&Sure Biotech Co., LTD | 150 | 2019-08-21 | 2020-03-12 |
| Efficacy of Kangliuwan for Recurrent Grade IV Glioma Glioma of Brain, Recurrence | Unknown | Xuanwu Hospital, Beijing | 20 | 2019-06-28 | 2020-05-05 | |
| Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma Topotecan - Glioma of Brain | Early Phase 1 | Terminated | H. Lee Moffitt Cancer Center and Research Institute | 3 | 2019-06-20 | 2023-05-25 |
| Safety and Efficacy of L19TNF in Patients With Isocitrate Dehydrogenase (IDH) Wildtype WHO Grade III / IV Glioma at First Relapse L19TNF - Glioma of Brain | Phase 1 / Phase 2 | Completed | Philogen S.p.A. | 20 | 2019-05-31 | 2023-06-29 |
| V-Boost Immunotherapy in Glioblastoma Multiforme Brain Cancer V-Boost - Glioblastoma Multiforme, Glioma of Brain | Phase 2 | Unknown | Immunitor LLC | 20 | 2019-04-16 | 2019-04-17 |
| A Study Utilizing Escitalopram in Glioma Patients Escitalopram Oral Capsules - Glioma of Brain, Glioma | Phase 2 | Recruiting | University of Nebraska | 20 | 2019-03-06 | 2026-04-17 |
| Pilot Study of Mirtazapine for the Dual Tx of Depression and CINV in High-Grade Glioma Pts on TMZ Mirtazapine (Remeron) - Glioma of Brain | Phase 2 | Active not recruiting | University of California, Irvine | 120 | 2019-02-26 | 2025-09-24 |
| Seizure Prophylaxis in Patients With Glioma or Brain Metastasis Lacosamide, Levetiracetam - Glioma, Glioma of Brain | Phase 2 | Terminated | Duke University | 4 | 2019-01-31 | 2023-04-13 |
| A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection Ribociclib, Everolimus - Glioblastoma Multiforme, Glioma of Brain | Early Phase 1 | Completed | St. Joseph's Hospital and Medical Center, Phoenix | 27 | 2019-01-19 | 2025-05-30 |
| Visual Study of Molecular Genotype in Glioma Evolution Glioma of Brain | Unknown | Tongji Hospital | 1000 | 2019-01-01 | 2019-03-26 | |
| Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma Specialized tumor board recommendation - Glioma, Glioma of Brain | Not applicable | Completed | University of California, San Francisco | 44 | 2018-11-28 | 2026-08-11 |
| Pembrolizumab in Association With the IMA950/Poly-ICLC for Relapsing Glioblastoma IMA950/Poly-ICLC, IMA950/Poly-ICLC and pembrolizumab - Glioblastoma Multiforme, Glioblastoma, Adult | Phase 1 / Phase 2 | Completed | University Hospital, Geneva | 18 | 2018-10-25 | 2025-05-13 |
| Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently Multilingual Aphasia Examination, Language paradigms + RS fMRI, Language paradigms + RS fMRI + one anatomical sequence - Glioma, Glioma of Brain | Completed | Memorial Sloan Kettering Cancer Center | 32 | 2018-03-30 | 2025-05-11 | |
| Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors Memantine, Placebo, Cognitive Assessment - Glioma of Brain, Craniopharyngioma | Phase 2 | Completed | St. Jude Children's Research Hospital | 41 | 2017-11-07 | 2026-06-23 |
| Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM Capecitabine, Temozolomide - Glioblastoma Multiforme (GBM), Glioblastoma | Phase 1 / Phase 2 | Recruiting | Northwell Health | 67 | 2017-06-13 | 2026-06-01 |
| The Efficacy of APT Magnetic Resonance Imaging in Predicting the Efficacy of Bevacizumab in Recurrent Malignant Gliomas APT MR Imaging - Diagnoses Disease, Glioma of Brain | Unknown | Zhujiang Hospital | 100 | 2017-06-03 | 2017-06-08 |
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Glioma (15) · Brain Neoplasms (8) · Glioblastoma (8) · Neoplasms (3) · Melanoma (2) · Astrocytoma (1) · Craniopharyngioma (1) · Ependymoma (1) · Neoplasms, Germ Cell and Embryonal (1) · Recurrence (1)
Neoplasms by Histologic Type (20) · Neoplasms, Nerve Tissue (20) · Neuroectodermal Tumors (20) · Neoplasms, Germ Cell and Embryonal (19) · Neoplasms, Glandular and Epithelial (19) · Neoplasms, Neuroepithelial (19) · Neoplasms (17) · Neoplasms by Site (9) · Brain Diseases (8) · Central Nervous System Diseases (8) · Central Nervous System Neoplasms (8) · Nervous System Diseases (8) · Nervous System Neoplasms (8) · Astrocytoma (7) · Glioma (4)
Temozolomide (3) · Radiotherapy (2) · pembrolizumab (2) · Bevacizumab (1) · Capecitabine (1) · Escitalopram (1) · Everolimus (1) · Heat-Shock Response (1) · Ipilimumab (1) · Ketoconazole (1) · Lacosamide (1) · Language Tests (1) · Levetiracetam (1) · Medication Errors (1) · Memantine (1)
Center Trials & Treatment (2) · Cancer Trials Ireland (1) · Chang Gung Memorial Hospital (1) · Cure&Sure Biotech Co., LTD (1) · Duke University (1) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (1) · Fuda Cancer Hospital, Guangzhou (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Hospital Sirio-Libanes (1) · Immunitor LLC (1) · Memorial Sloan Kettering Cancer Center (1) · Northwell Health (1) · Philogen S.p.A. (1) · St. Joseph's Hospital and Medical Center, Phoenix (1) · St. Jude Children's Research Hospital (1)
United States (11) · China (5) · Switzerland (3) · Italy (2) · Albania (1) · Belarus (1) · Belgium (1) · Bosnia and Herzegovina (1) · Brazil (1) · Bulgaria (1) · Canada (1) · Croatia (1) · Hong Kong (1) · Ireland (1) · Mongolia (1)
Aldar Bourinbayar, MD/PhD (1) · Andrei Holodny, MD (1) · Annick Desjardins, M.D. (1) · Daniela Bota, MD PHD (1) · Gelareh Zadeh, MD, PhD (1) · Heather M. Conklin, PhD (1) · Jochen Prehn (1) · John Boockvar, MD (1) · Kevin A Walter, MD (1) · Krishna Nayak, PhD (1) · Ling Chen, M.D. (1) · Michael Vogelbaum, M.D, PhD (1) · Nader Sanai, MD (1) · Nicolas Mach, Prof. (1) · Nicole A Shonka, MD (1)
PMID 35343323, PMID 38883740, PMID 41206763
P30CA014089 (1), R21CA218625 (1), R33CA225400 (1)