13 terminated. 13 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 13 | Terminated 13 |
Follow Glaucoma: new trials by email Literature Review of Glaucoma trials Research Report on Glaucoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| EffiCacy, Safety and ToLErability of a Novel Ocular ANtiseptic for Ocular Use (CLEAN) IRX-101, Control - Diabetic Macular Edema, Branch Retinal Vein Occlusion | Phase 3 | Terminated | iRenix Medical, Inc. | 5 | 2021-11-15 | 2022-05-24 |
| PRO-122 Versus Concomitant Therapy in Subjects With Uncontrolled Primary Open-angle Glaucoma (PRO-122LATAM) PRO-122, Timolol eye drops, Dorzolamide-Timolol Ophthalmic - Primary Open-angle Glaucoma | Phase 3 | Terminated | Laboratorios Sophia S.A de C.V. | 51 | 2017-11-06 | 2025-03-06 |
| Antisecretory Factor (AF) Effects on Intraocular-pressure Salovum, Placebo - Glaucoma | Phase 3 | Terminated | St. Erik Eye Hospital | 50 | 2016-04-01 | 2021-05-14 |
| Stop Retinal Ganglion Cell Dysfunction Study Latanoprost, Bimatoprost, Travoprost - Glaucoma | Phase 3 | Terminated | University of Miami | 28 | 2015-09-01 | 2025-08-26 |
| Non-inferiority of PRO-067 Ophthalmic Solution vs GAAP Ofteno® in Glaucoma or Ocular Hypertension PRO-067, GAAP Ofteno® - Primary Open Angle Glaucoma, Ocular Hypertension | Phase 3 | Terminated | Laboratorios Sophia S.A de C.V. | 116 | 2015-09-01 | 2024-07-05 |
| A Study of the Safety and Efficacy of Bimatoprost Ophthalmic Solution in Paediatric Patients With Glaucoma bimatoprost ophthalmic solution formulation A, timolol ophthalmic solution, bimatoprost vehicle - Glaucoma | Phase 3 | Terminated | Allergan | 6 | 2011-09-01 | 2015-10-02 |
| DuoTrav APS Versus XALACOM® in Ocular Surface Health DuoTrav APS, Xalacom - Open Angle Glaucoma, Ocular Hypertension | Phase 3 | Terminated | Alcon Research | 240 | 2010-03-01 | 2012-07-19 |
| Trabectome Versus Trabeculectomy With Mitomycin C in Patients With Open Angle Glaucoma Trabectome-IOL, Trab-IOL - Open Angle Glaucoma | Phase 3 | Terminated | University of Alberta | 19 | 2009-11-01 | 2016-02-25 |
| Travoprost/Brinzolamide Fixed Combination Versus Travatan and Versus AZOPT Travoprost/Brinzolamide fixed combination, Azopt, Travatan - Glaucoma, Ocular Hypertension | Phase 3 | Terminated | Alcon Research | 17 | 2008-10-01 | 2012-09-19 |
| 1 Year Study Trav/Brinz QD Fixed Combination Versus COSOPT Travoprost/Brinzolamide, Cosopt - Glaucoma, Ocular Hypertension | Phase 3 | Terminated | Alcon Research | 6 | 2008-10-01 | 2012-07-19 |
| Timing of Treatment Completion in Staged Selective Laser Trabeculoplasty (SLT): Early vs. Late Completion selective laser trabeculoplasty - early completion, Selective laser trabeculoplasty - late completion - Glaucoma | Phase 3 | Terminated | Queen's University | 20 | 2007-09-01 | 2015-09-23 |
| OculusGen-Glaucoma Historical Control Study in Taiwan OculusGen Biodegradable Collagen Matrix Implant - Glaucoma | Phase 3 | Terminated | Pro Top & Mediking Company Limited | 48 | 2006-12-01 | 2008-05-05 |
| Acupuncture for Elevated Intraocular Pressure acupuncture - Elevated Intraocular Pressure | Phase 3 | Terminated | Shaare Zedek Medical Center | 10 | 2006-05-01 | 2007-10-02 |
Ocular Hypertension (6) · Glaucoma, Open-Angle (5) · Cataract (1) · Glaucoma, Angle-Closure (1) · Retinal Vein Occlusion (1)
Eye Diseases (13) · Ocular Hypertension (7) · Cardiovascular Diseases (1) · Embolism and Thrombosis (1) · Lens Diseases (1) · Retinal Diseases (1) · Thrombosis (1) · Vascular Diseases (1) · Venous Thrombosis (1)
Travoprost (3) · brinzolamide (3) · Bimatoprost (2) · Latanoprost (2) · Timolol (2) · dorzolamide (2) · Acetazolamide (1) · Acupuncture Therapy (1) · Brimonidine Tartrate (1) · Methazolamide (1) · Prostaglandins (1) · Xalacom (1) · dorzolamide-timolol combination (1)
Alcon Research (3) · Laboratorios Sophia S.A de C.V. (2) · Allergan (1) · Pro Top & Mediking Company Limited (1) · Queen's University (1) · Shaare Zedek Medical Center (1) · St. Erik Eye Hospital (1) · University of Alberta (1) · University of Miami (1) · iRenix Medical, Inc. (1)
Mexico (3) · United States (3) · Belgium (2) · Canada (2) · Taiwan (2) · Colombia (1) · France (1) · Israel (1) · Italy (1) · Philippines (1) · South Korea (1) · Sweden (1) · United Kingdom (1)
Enping Chen, MD PhD (1) · Henry SL Chen, MD (1) · Karim F Damji, MD FRCSC MBA (1) · Leopoldo Baiza, MD (1) · Menachem Oberbaum, M.D. (1) · Robert J Campbell, MD (1) · Stephen Smith, MD, MS (1) · Vittorio Porciattti, DSc (1)
PMID 10937547, PMID 27526051, PMID 33580495, PMID 35943114, PMID 41737851
2008 (1), R01EY014957 (1)