17 completed, 2 not yet recruiting, 1 active not recruiting, 1 enrolling by invitation. 12 Not applicable, 3 Phase 1, 2 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 10, Active not recruiting 1, Enrolling by invitation 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 4 | 2 | Completed 1, Not yet recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow Fluorosis, Dental: new trials by email Literature Review of Fluorosis, Dental trials Research Report on Fluorosis, Dental
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effectiveness of Antivet Versus Opalustre® for the Management of Enamel Fluorosis/Discolored Enamel and Its Impact on Aesthetic Outcomes. Antivet, Opalusture - Fluorosis, Dental, Enamel Discoloration | Not applicable | Completed | October University for Modern Sciences and Arts | 59 | 2026-05-18 | 2026-07-16 |
| Clinical Severity of Dental Fluorosis and Associated Risk Factors Among a Group of Children in Rural Region, Dendera Center in Egypt Dental Fluorosis | Not yet recruiting | Cairo University | 231 | 2026-02-20 | 2025-08-22 | |
| 3D Scanning as an Advanced Tool for Identifying Tooth Lesions in Children indirect- 3D digital scanning - Dental Caries in Children, Tooth Erosion | Not applicable | Completed | Indiana University | 36 | 2025-11-04 | 2026-05-06 |
| Design of a Multicomponent Intervention to Reduce the Risk of Exposure Fluorine multicomponent intervention, Conventional intervention - Fluorosis, Dental, Fluorosis | Not applicable | Enrolling by invitation | Universidad Antonio Nariño | 90 | 2025-08-01 | 2026-01-22 |
| Design of a Multicomponent Intervention to Reduce the Risk of Exposure Fluorine multicomponent intervention, Conventional intervention - Fluorosis, Dental, Fluorosis | Not applicable | Active not recruiting | Universidad Antonio Nariño | 90 | 2025-05-02 | 2026-01-14 |
| 21% Hydrochloric Acid Based Versus 6.6 % Hydrochloric Based Micro Abrasive Kit in Management of Patients With Mild to Moderate Fluorosis Antivet, opalustre - Enamel Discoloration, Fluorosis, Dental | Phase 4 | Not yet recruiting | Cairo University | 35 | 2025-05-01 | 2025-04-29 |
| Resin Infiltration Versus Microabrasion With CPP-ACP for Fluorotic White Spot Lesions Resin infiltration, Enamel Microabrasion Plus CPP-ACP - Dental Fluorosis | Not applicable | Completed | Hue University of Medicine and Pharmacy | 42 | 2023-06-01 | 2026-07-15 |
| Colorimetric, Ultra-structural and Elemental Comparison of Dental Enamel Defects spectrophotometer, Biological (protein analysis by western blot or mass spectrometry of matrix proteins), structural (electron microscopy) and physico-chemical analyses - Amelogenesis Imperfecta, Dental Fluoroses | Recruiting | Assistance Publique - Hôpitaux de Paris | 80 | 2022-07-18 | 2025-07-03 | |
| This is the Comparison of Clinical Effectiveness of Hydrochloric Acid-pumice Compound and Sodium Hypochlorite-pumice Compound Used in Microabrasion Technique for the Treatment of Dental Fluorosis. Change in Tooth Shade Was Checked Before and After the Procedure. enamel microabrasion - Dental Fluoroses | Not applicable | Completed | Fatima Jinnah Dental College | 60 | 2019-11-01 | 2022-05-02 |
| Clinical Evaluation of Dental Fluororsis Treatment Modalities Opalescence™ boost™ PF 40%, Opalustre™, MI-Paste Plus® - Dental Fluorosis | Not applicable | Completed | Suez Canal University | 16 | 2019-09-08 | 2022-01-24 |
| Clinical Evaluation of Different Minimal Invasive Treatment Modalities of Mild to Moderate Dental Fluorosis Using A Visual Analog Scale Opalescence™ boost™ PF 40%, Opalustre™, MI-Paste Plus® - Dental Fluorosis | Not applicable | Completed | Suez Canal University | 16 | 2019-09-08 | 2021-09-21 |
| Using Eggshell Calcium to Mitigate Fluorosis in Ethiopia Promotion of chicken eggs - Fluoride Poisoning, Hemoglobin | Not applicable | Completed | University of Saskatchewan | 270 | 2018-01-02 | 2020-11-03 |
| Presence of Enamel Fluorosis in Libyan Children Dental Fluorosis | Completed | Ajman University | 1935 | 2017-01-10 | 2018-11-20 | |
| Dental Fluorosis Risk by the Use of Acidulated Fluoride Dentifrice Use of Dentifrice Fluoride - Caries, Dental, Fluorosis, Dental | Phase 4 | Completed | Federal University of Paraíba | 452 | 2015-01-15 | 2018-12-03 |
| Treatment of Hypersensitivity Using Diode Laser and Desensitising Agent on Fluorosed and Non-fluorosed Teeth Fluorosed Group, Non Flourosed Group - Fluorosis, Dental, Non-Fluoride Enamel Opacities | Not applicable | Completed | Krishnadevaraya College of Dental Sciences & Hospital | 90 | 2014-07-01 | 2017-08-08 |
| Fluoride Bioavailability After Ingestion of Water or Foods Prepared With Fluoridated Water Meal prepared with non fluoridated water, Meal prepared with fluoridated water, Non fluoridated water - Dental Caries, Dental Fluorosis | Phase 1 | Completed | University of Campinas, Brazil | 20 | 2013-01-01 | 2015-05-28 |
| Anticaries Potential and Fluorosis Risk From Different Fluoride Toothpastes Toothpaste - Dental Caries, Dental Fluorosis | Phase 1 | Completed | University of Campinas, Brazil | 24 | 2011-01-01 | 2013-10-28 |
| Systemic Fluoride Bioavailability From Toothpastes Containing Calcium Carbonate or Silica as Abrasives Purified water, Fresh MFP/CaCO3 toothpaste, Fresh NaF/SiO2 toothpaste - Dental Fluorosis | Phase 1 | Completed | University of Campinas, Brazil | 20 | 2011-01-01 | 2012-04-04 |
| Nails and Teeth as Biomarkers of Fluoride Exposure Biodent Toothpaste (Ilirija d.d., Ljubljana, Slovenia) - Fluorosis, Dental | Not applicable | Completed | University of Ljubljana | 342 | 2010-01-03 | 2022-07-05 |
| Effect of pH and Fluoride Concentration of Dentifrices on Caries Control Low fluoride and conventional dentifrices with different pH - Dental Fluorosis, Dental Caries | Phase 3 | Completed | University of Sao Paulo | 315 | 2009-11-01 | 2012-08-30 |
Showing 20 of 22. Sign in to see all of them.
Dental Caries (6) · Fluoride Poisoning (4) · Health Education (2) · Amelogenesis Imperfecta (1) · Dentin Sensitivity (1) · Developmental Defects of Enamel (1) · Disease (1) · Growth Disorders (1) · Molar Hypomineralization (1) · Motor Activity (1) · Plaque, Amyloid (1) · Thinness (1) · Tooth Erosion (1) · Tooth Wear (1)
Congenital Abnormalities (22) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (22) · Dental Enamel Hypomineralization (22) · Stomatognathic Diseases (22) · Stomatognathic System Abnormalities (22) · Tooth Abnormalities (22) · Tooth Diseases (22) · Developmental Defects of Enamel (21) · Tooth Demineralization (6) · Chemically-Induced Disorders (4) · Poisoning (4) · Behavior (3) · Pathological Conditions, Signs and Symptoms (3) · Adherence Interventions (2) · Health Behavior (2)
opalustre (3) · Enamel Microabrasion (2) · Biological Products (1) · Dentifrices (1) · Microscopy, Electron (1) · Toothpastes (1) · casein phosphopeptide-amorphous calcium phosphate nanocomplex (1)
University of Campinas, Brazil (3) · Cairo University (2) · Suez Canal University (2) · Universidad Antonio Nariño (2) · Ajman University (1) · Assistance Publique - Hôpitaux de Paris (1) · Fatima Jinnah Dental College (1) · Federal University of Minas Gerais (1) · Federal University of Paraíba (1) · Hue University of Medicine and Pharmacy (1) · Indiana University (1) · Krishnadevaraya College of Dental Sciences & Hospital (1) · October University for Modern Sciences and Arts (1) · Steven M Levy (1) · University of Ljubljana (1)
Brazil (5) · Egypt (4) · Colombia (2) · Ethiopia (1) · France (1) · Pakistan (1) · United States (1) · Vietnam (1)
Livia MA Tenuta, PhD (3) · Aline Castilho, DDS (1) · Carolina C Martins, PhD (1) · Rashmi Paramashivaiah, MDS (1) · Steven M Levy, dds (1) · Susan Whiting, PhD (1) · Van Nhat Thang Le, DDS PhD (1)
PMID 21180793, PMID 22163207, PMID 23295625, PMID 23873319, PMID 24588784, PMID 28762354, PMID 30638821, PMID 32149058, PMID 33109505, PMID 33804976, PMID 41469534, PMID 42031231