3 completed, 3 not yet recruiting, 3 recruiting, 3 unknown. 10 Not applicable, 2 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 3, Not yet recruiting 2, Recruiting 2, Unknown 2, Active not recruiting 1 |
| Early Phase 1 | 2 | Not yet recruiting 1, Recruiting 1 |
Follow Epilepsy, Drug Resistant: new trials by email Literature Review of Epilepsy, Drug Resistant trials Research Report on Epilepsy, Drug Resistant
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Piriform Cortex Electrical Stimulation for Temporal Lobe Epilepsy With Biliteral Hippocampus Sclerosis piriform cortex-DBS - Epilepsy, Drug Resistant | Not applicable | Not yet recruiting | Xuanwu Hospital, Beijing | 5 | 2025-09-10 | 2025-08-19 |
| Non-Invasive Low Intensity Focused Ultrasound Stimulation for Drug-Resistant Epilepsy Target optimization using LIFU, Serial LIFU stimulation - Drug-Resistant Epilepsy, Epilepsy | Not applicable | Recruiting | University of California, San Francisco | 40 | 2025-07-09 | 2026-07-02 |
| Sirolomus Adjuvant Treatment of Focal Refractory Epilepsy (SATFRE) Sirolimus - Epilepsy, Drug Resistant | Early Phase 1 | Recruiting | Xuanwu Hospital, Beijing | 15 | 2024-12-23 | 2024-12-31 |
| Propranolol Adjuvant Treatment of Focal Refractory Epilepsy (PATFRE) Propranolol - Epilepsy, Drug Resistant | Early Phase 1 | Not yet recruiting | Xuanwu Hospital, Beijing | 15 | 2024-12-05 | 2024-12-10 |
| Extreme Capsule Electrical Stimulation for Drug-resistant Focal Epilepsy EC-DBS ON - Epilepsy, Drug Resistant | Not applicable | Not yet recruiting | Xuanwu Hospital, Beijing | 10 | 2024-11-01 | 2024-10-29 |
| Enhancing Epilepsy Management With Precision Deep Brain Stimulation Neuromodulation programming - Epilepsy, Drug Resistant | Not applicable | Unknown | Nova Scotia Health Authority | 40 | 2024-06-01 | 2024-04-15 |
| Subiculum Electrical Stimulation for Temporal Lobe Epilepsy With Biliteral Hippocampus Sclerosis(SESTB) Subiculum-DBS ON - Epilepsy, Drug Resistant | Not applicable | Active not recruiting | Xuanwu Hospital, Beijing | 6 | 2024-06-01 | 2025-11-19 |
| Subthalamic Nucleus Electrical Stimulation for Drug-resistant Focal Motor Epilepsy STN-DBS ON, STN-DBS OFF - Epilepsy, Drug Resistant | Not applicable | Recruiting | Xuanwu Hospital, Beijing | 33 | 2024-02-14 | 2025-07-15 |
| Effectiveness and Safety of Thread Embedding Acupuncture for Drug Resistant Epilepsy Thread Embedding Acupuncture (TEA), Sham-TEA (STEA) - Epilepsy, Drug Resistant, Acupuncture Therapy | Not applicable | Unknown | University of Medicine and Pharmacy at Ho Chi Minh City | 60 | 2020-11-17 | 2021-08-26 |
| Deep Brain Stimulation Post Failed Vagal Nerve Stimulation Deep brain stimulation - Epilepsy, Drug Resistant | Not applicable | Completed | The Hospital for Sick Children | 25 | 2019-11-25 | 2024-03-05 |
| Drug Resistant Epilepsy: Clinical and Genetic Study Genetic study for SCN1A c.3184 A/G and CCL2-2518G>A polymorphism: - Epilepsy, Drug Resistant | Unknown | Mansoura University Hospital | 180 | 2019-11-01 | 2019-11-18 | |
| Safety of Using NaviFUS System in Patients With Drug Resistant Epilepsy NaviFUS System - Drug Resistant Epilepsy, Epilepsy, Drug Resistant | Not applicable | Completed | NaviFUS Corporation | 6 | 2019-06-17 | 2020-11-13 |
| Efficacy, Tolerability and Adherence of the Modified Atkins Diet on Drug-resistant Epilepsy modified adkins diet, Pharmacotherapy without diet - Epilepsy, Drug Resistant | Not applicable | Completed | Instituto Mexicano del Seguro Social | 14 | 2015-09-01 | 2017-06-09 |
Drug Resistant Epilepsy (13) · Epilepsy (3) · Epilepsies, Partial (2) · Epilepsy, Generalized (1) · Epilepsy, Partial, Motor (1) · Seizures (1)
Brain Diseases (13) · Central Nervous System Diseases (13) · Nervous System Diseases (13) · Epilepsy (10) · Epilepsies, Partial (1) · Neurologic Manifestations (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1)
Anticonvulsants (1) · Deep Brain Stimulation (1) · Diet (1) · Drug Therapy (1) · Propranolol (1) · Sirolimus (1) · Therapeutics (1)
Xuanwu Hospital, Beijing (6) · Instituto Mexicano del Seguro Social (1) · Mansoura University Hospital (1) · NaviFUS Corporation (1) · Nova Scotia Health Authority (1) · The Hospital for Sick Children (1) · University of California, San Francisco (1) · University of Medicine and Pharmacy at Ho Chi Minh City (1)
China (4) · Canada (2) · Egypt (1) · Mexico (1) · Taiwan (1) · United States (1) · Vietnam (1)
Liankun Ren, MD (6) · Zhuo Huang, PhD (2) · Dan V Nguyen, MD (1) · Esmael M Ahmed, MD (1) · George Ibrahim (1) · Hsiang-Yu Yu, M.D. (1) · Joline M Fan, MD, MS (1) · Lutz Weise, MD, PhD (1)
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