Down Syndrome: Clinical Trials

4 terminated. 4 Phase 3.

By phase and status

Phase	Trials	Status
Phase 3	4	Terminated 4

Follow Down Syndrome: new trials by email Literature Review of Down Syndrome trials Research Report on Down Syndrome

Trials (filtered) newest first · largest first

All 4 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
LIFE-DSR-Biomarker Sub-study of Biomarkers in Down Syndrome Related Alzheimer's Disease (DS-AD) [18F]MK-6240 - Down Syndrome	Phase 3	Terminated	LuMind IDSC Foundation	5	2023-06-27	2025-03-06
Preimplantation Genetic Diagnosis (PGD) by Array Comparative Genome Hybridization (CGH) and Blastocyst Biopsy Preimplantation Genetic Diagnosis - Infertility, Miscarriage	Phase 3	Terminated	Reprogenetics	120	2011-04-01	2012-05-30
Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 11 To 17 Aricept (donepezil hydrochloride), Placebo - Down Syndrome, Cognitive Dysfunction	Phase 3	Terminated	Eisai Inc.	8	2008-09-01	2018-04-23
Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 6 To 10 Aricept (Donepezil hydrochloride), Placebo - Down Syndrome, Cognitive Dysfunction	Phase 3	Terminated	Eisai Inc.	9	2008-09-01	2020-01-28

Narrower conditions

Cognitive Dysfunction (2)  ·  Abortion, Spontaneous (1)  ·  Infertility (1)

Broader conditions

Abnormalities, Multiple (4)  ·  Chromosome Disorders (4)  ·  Congenital Abnormalities (4)  ·  Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4)  ·  Genetic Diseases, Inborn (4)  ·  Intellectual Disability (4)  ·  Nervous System Diseases (4)  ·  Neurobehavioral Manifestations (4)  ·  Neurologic Manifestations (4)  ·  Cognition Disorders (2)  ·  Mental Disorders (2)  ·  Neurocognitive Disorders (2)  ·  Female Urogenital Diseases and Pregnancy Complications (1)  ·  Genital Diseases (1)  ·  Pregnancy Complications (1)

Interventions

Donepezil (2)

Sponsors

Eisai Inc. (2)  ·  LuMind IDSC Foundation (1)  ·  Reprogenetics (1)

Countries

United States (3)  ·  Peru (1)

Top investigators

Thomas McRae, MD (2)  ·  Santiago Munne, PhD (1)