3 completed. 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 3 |
Follow Desmoid Tumors: new trials by email Literature Review of Desmoid Tumors trials Research Report on Desmoid Tumors
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF) Nirogacestat oral tablet, Placebo Oral Tablet - Desmoid Tumor, Aggressive Fibromatosis | Phase 3 | Completed | SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany | 142 | 2019-04-17 | 2026-08-20 |
| Sorafenib Tosylate in Treating Patients With Desmoid Tumors or Aggressive Fibromatosis Laboratory Biomarker Analysis, Placebo Administration, Quality-of-Life Assessment - Desmoid Fibromatosis | Phase 3 | Completed | National Cancer Institute (NCI) | 87 | 2014-03-21 | 2026-06-24 |
| Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Fentanyl sublingual spray, Placebo - Cancer | Phase 3 | Completed | INSYS Therapeutics Inc | 130 | 2007-10-01 | 2014-03-05 |
Adrenocortical Carcinoma (1) · Anus Neoplasms (1) · Appendiceal Neoplasms (1) · Astrocytoma (1) · Bile Duct Neoplasms (1) · Blast Crisis (1) · Brain Neoplasms (1) · Breast Carcinoma In Situ (1) · Breast Neoplasms (1) · Breast Neoplasms, Male (1) · Burkitt Lymphoma (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Islet Cell (1) · Carcinoma, Non-Small-Cell Lung (1)
Fibroma (3) · Neoplasms by Histologic Type (3) · Neoplasms, Connective Tissue (3) · Neoplasms, Connective and Soft Tissue (3) · Neoplasms, Fibrous Tissue (3) · Neoplasms (2) · Adenocarcinoma (1) · Adenoma (1) · Adenoma, Islet Cell (1) · Adnexal Diseases (1) · Adrenal Cortex Diseases (1) · Adrenal Cortex Neoplasms (1) · Adrenal Gland Diseases (1) · Adrenal Gland Neoplasms (1) · Amyloidosis (1)
Fentanyl (1) · Sorafenib (1) · nirogacestat (1)
INSYS Therapeutics Inc (1) · National Cancer Institute (NCI) (1) · SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany (1)
United States (3) · Canada (2) · Belgium (1) · Germany (1) · Italy (1) · Netherlands (1) · United Kingdom (1)
Bernd Kasper, MD (1) · Larry Dillaha, MD (1) · Mrinal M Gounder (1)
PMID 22480131, PMID 27020837, PMID 30575484, PMID 33258687, PMID 34420143, PMID 36884323, PMID 37347393, PMID 41115259
U10CA031946 (1), U10CA180821 (1)