4 completed, 2 terminated. 6 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 4, Terminated 2 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
Follow Deltaretrovirus Infections: new trials by email Literature Review of Deltaretrovirus Infections trials Research Report on Deltaretrovirus Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of KW-0761 in Subjects With HTLV-1 Associated Myelopathy (HAM) KW-0761 0.3 mg/kg IV, Placebo (saline) - HTLV-1 Associated Myelopathy | Phase 3 | Terminated | Kyowa Kirin Co., Ltd. | 66 | 2017-05-22 | 2022-04-14 |
| Efficacy and Safety of Tamibarotene(AM80H) for HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP) Tamibarotene - HTLV-I-Associated Myelopathy | Phase 2 / Phase 3 | Terminated | St. Marianna University School of Medicine | 15 | 2011-01-01 | 2026-10-08 |
| Use of Pentoxifylline in Human T-lymphotropic Virus Type-1 (HTLV-1) Diseases Pentoxifylline, Placebo - HTLV-1, Tropical Spastic Paraparesis | Phase 3 | Completed | Hospital Universitário Professor Edgard Santos | 48 | 2009-09-01 | 2015-03-18 |
| Use Of Valproid Acid To Treat Tropical Spastic Paraparesis/HTLV-1-Associated Myelopathy (TSP/HAM) Valproic acid, costicosteroids, valproid acid plus corticosteroids - Paraparesis Spastic Tropical | Phase 3 | Completed | University of Sao Paulo | 60 | 2008-02-01 | 2015-12-03 |
| Ciclosporin in HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP) ciclosporin - HTLV I Associated Myelopathy | Phase 2 / Phase 3 | Completed | Imperial College London | 7 | 2006-08-01 | 2021-09-09 |
| Zidovudine Plus Lamivudine in HTLV-I-associated Myelopathy: a Randomised Trial Zidovudine/lamivudine, Placebos - HTLV-I-associated Myelopathy | Phase 2 / Phase 3 | Completed | Imperial College London | 16 | 1999-11-08 | 2021-08-25 |
Paraparesis, Tropical Spastic (6) · Immune System Diseases (1)
Central Nervous System Diseases (6) · Central Nervous System Infections (6) · HTLV-I Infections (6) · Infections (6) · Myelitis (6) · Nervous System Diseases (6) · Neuroinflammatory Diseases (6) · RNA Virus Infections (6) · Retroviridae Infections (6) · Spinal Cord Diseases (6) · Virus Diseases (6)
Adrenal Cortex Hormones (1) · Cyclosporine (1) · Pentoxifylline (1) · Sodium Chloride (1) · Valproic Acid (1) · lamivudine, zidovudine drug combination (1) · mogamulizumab (1) · tamibarotene (1)
Imperial College London (2) · Hospital Universitário Professor Edgard Santos (1) · Kyowa Kirin Co., Ltd. (1) · St. Marianna University School of Medicine (1) · University of Sao Paulo (1)
Brazil (2) · Japan (2) · United Kingdom (2)
Davi Costa, MD (1) · Edgar M Carvalho, MD, PhD (1) · Graham P Taylor (1) · Graham P Taylor, FRCP (1) · Yoshihisa Yamano, MD (1)