10 completed, 4 recruiting, 1 terminated, 1 unknown. 7 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 4, Recruiting 2, Unknown 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 4 | 1 | Terminated 1 |
Follow Craniofacial Dysostosis: new trials by email Literature Review of Craniofacial Dysostosis trials Research Report on Craniofacial Dysostosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment for "Asymmetric Crying Facies" Botulinium toxin type A injection - Hemifacial Microsomia, Facial Nerve Paralysis | Not applicable | Recruiting | Xiaolei Jin | 60 | 2026-08-07 | 2026-09-28 |
| Clinical Evaluation of Patient-Specific 3D-Printed Titanium Implants for Facial Reconstruction. Patient-specific titanium implants for facial reconstruction - Hemifacial Microsomia, Mucormycosis | Not applicable | Recruiting | Latakia University | 30 | 2026-04-26 | 2026-06-17 |
| ASO Treatment for Syndromic Craniosynostoses Design of patient specific ASO - Craniosynostoses, Crouzon Syndrome | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 12 | 2026-04-20 | 2026-09-08 | |
| A Post Market Clinical Follow-up Study on Biomet Microfixation HTR PEKK (Midface), Facial & Mandibular Plates. Titanium Facial Plates, Titanium Mandibular Plates, Add-on Condyle - Tumor, Facial Fracture | Completed | Zimmer Biomet | 91 | 2021-10-01 | 2024-01-29 | |
| Efficacy of Preconditioned Adipose-Derived Stem Cells in Fat Grafting Cultured ASCs enrichment fat grafting, Curcumin-preconditioned ASCs enrichment fat grafting, Conventional fat grafting - Romberg Disease, Craniofacial Microsomia | Phase 1 | Recruiting | University of the Punjab | 24 | 2020-11-20 | 2024-12-31 |
| Fat Grafts With Adipose-derived Regenerative Cells for Soft Tissue Reconstruction in Children Fat grafts supplemented with ADRC, Structural fat grafting - Craniofacial Microsomia | Not applicable | Completed | Hospital Sirio-Libanes | 30 | 2019-01-10 | 2021-10-18 |
| A Study of Crisaborole Ointment 2%; Crisaborole Vehicle; TCS and TCI in Subjects Aged ≥ 2 Years, With Mild-moderate AD Crisaborole ointment, 2%, Hydrocortisone butyrate cream, 0.1%, Pimecrolimus cream, 1% - Atopic Dermatitis | Phase 4 | Terminated | Pfizer | 237 | 2018-04-27 | 2022-01-10 |
| Craniofacial Microsomia: Accelerating Understanding of the Significance and Etiology Microtia, Microtia-Anotia | Completed | Seattle Children's Hospital | 935 | 2018-02-23 | 2024-04-22 | |
| Computer Guided for Mandibular Distraction Osteogenesis 3D printed surgical guide constructed, free hand surgery - Hemifacial Microsomia | Not applicable | Completed | Yasser Mohamed Nabil Ahmed Khirat El Hadidi | 12 | 2015-12-30 | 2019-03-11 |
| Evaluation of Effect of Bone Marrow Aspirate Concentrate on Distracted Mandibular Bone Properties Bone Marrow Aspirate Concentrate, Saline - Hemifacial Microsomia, Distraction of Bone | Not applicable | Completed | Yasser Mohamed Nabil Ahmed Khirat El Hadidi | 12 | 2015-12-30 | 2019-03-04 |
| Role of Mesenchymal Stem Cells in Fat Grafting Fat graft enriched with ex vivo expanded stem cells, Fat graft not enriched with ex vivo expanded stem cells - Romberg's Disease, Craniofacial Microsomia | Not applicable | Unknown | King Edward Medical University | 30 | 2015-08-01 | 2015-07-10 |
| Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK) Craniofacial Microsomia, Hemifacial Microsomia | Completed | Seattle Children's Hospital | 417 | 2013-11-01 | 2024-04-19 | |
| Study of a Candidate Gene Involved in Goldenhar Syndrome. Goldenhar Syndrome, Oculoauriculovertebral Dysplasia | Completed | University Hospital, Bordeaux | 248 | 2012-09-29 | 2019-08-14 | |
| Oxygen Insuflation and ArterialDesaturation During Tracheal Intubation in Children laryngoscopy with oxygen, laryngoscopy without oxygen - Infants, Difficult Airway | Not applicable | Completed | Medical University of Vienna | 48 | 2012-01-01 | 2023-08-31 |
| Clinical Trial of Fat Grafts Supplemented With Adipose-derived Regenerative Cells Supplementation of ADRC, Without supplementation of ADRC - Craniofacial Microsomia | Phase 2 | Completed | University of Sao Paulo | 29 | 2010-01-01 | 2012-08-28 |
| Positive Exposure: A Photography and Video Intervention for Individuals With Craniofacial Differences Craniofacial Differences | Completed | National Human Genome Research Institute (NHGRI) | 44 | 2005-06-13 | 2019-12-12 |
Goldenhar Syndrome (13) · Mandibulofacial Dysostosis (4) · Acrocephalosyndactylia (2) · Congenital Microtia (2) · Facial Asymmetry (2) · Facial Hemiatrophy (2) · Fibrous Dysplasia of Bone (2) · Acrofacial dysostosis, Nager type (1) · Bell Palsy (1) · Cleft Lip (1) · Coloboma (1) · Craniosynostoses (1) · Dermatitis, Atopic (1) · Diastasis, Bone (1)
Bone Diseases (16) · Bone Diseases, Developmental (16) · Congenital Abnormalities (16) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (16) · Craniofacial Abnormalities (16) · Dysostoses (16) · Musculoskeletal Abnormalities (16) · Musculoskeletal Diseases (16) · Mandibulofacial Dysostosis (11) · Nervous System Diseases (6) · Stomatognathic Diseases (6) · Eye Diseases (5) · Eye Diseases, Hereditary (5) · Mouth Diseases (5)
Laryngoscopy (1) · Oxygen (1) · Sodium Chloride (1) · crisaborole (1) · pimecrolimus (1)
Seattle Children's Hospital (2) · Yasser Mohamed Nabil Ahmed Khirat El Hadidi (2) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Hospital Sirio-Libanes (1) · King Edward Medical University (1) · Latakia University (1) · Medical University of Vienna (1) · National Human Genome Research Institute (NHGRI) (1) · Pfizer (1) · University Hospital, Bordeaux (1) · University of Sao Paulo (1) · University of the Punjab (1) · Xiaolei Jin (1) · Zimmer Biomet (1)
United States (4) · Brazil (2) · Italy (2) · Argentina (1) · Austria (1) · China (1) · Colombia (1) · Egypt (1) · Germany (1) · Pakistan (1) · Peru (1) · Poland (1) · Spain (1) · Sweden (1) · Switzerland (1)
Azra Mehmood, PhD (1) · Barbara B Biesecker (1) · Basim A Slim (1) · Carrie Heike, MD, MS (1) · Carrie L Heike, MD, MS (1) · Daniela Y Tanikawa, MD (1) · Mark Sun, PhD (1) · Matthew L Speltz, PhD (1) · Olga Plattner, M.D. (1) · Sheikh Riazuddin, PhD (1) · Wanda Lattanzi (1)
PMID 17763894, PMID 18513295, PMID 19912236, PMID 21999260, PMID 31002789, PMID 31827528, PMID 35534499, PMID 35734651, PMID 40655799
2018 (1), R01DE022438 (1)