1 completed, 1 enrolling by invitation, 1 recruiting, 1 withdrawn. 2 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 1, Enrolling by invitation 1 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 4 | 1 | Withdrawn 1 |
Follow Corneal Endothelial Decompensation: new trials by email Literature Review of Corneal Endothelial Decompensation trials Research Report on Corneal Endothelial Decompensation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of EO2002 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction 150K cells, 500K cells, Placebo - Corneal Edema, Fuchs | Phase 2 | Recruiting | Emmecell | 121 | 2026-10-01 | 2026-10-09 |
| Effect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 Years Descemet membrane endothelial keratoplasty - Fuchs Endothelial Corneal Dystrophy, Corneal Endothelial Decompensation | Not applicable | Enrolling by invitation | Case Western Reserve University | 570 | 2025-12-03 | 2026-02-27 |
| Impact of Donor Diabetes on DMEK Success and Endothelial Cell Loss Descemet membrane endothelial keratoplasty - Corneal Endothelial Decompensation, Fuchs' Endothelial Dystrophy | Not applicable | Completed | Case Western Reserve University | 1097 | 2022-01-21 | 2026-04-16 |
| Effect of Intracameral Dexamethasone After Phacoemulsification in Diabetics on Corneal Endothelial Cell Density Dexamethasone, Saline Solutions, Intraocular - Diabetes Mellitus, Corneal Endothelial Cell Loss | Phase 4 | Withdrawn | Cairo University | 2018-01-01 | 2019-07-24 |
Fuchs' Endothelial Dystrophy (3) · Corneal Endothelial Cell Loss (2) · Corneal Edema (1) · Corneal Endothelial Dystrophy 1 (1) · Corneal endothelial dystrophy type 2 (1) · Diabetes Mellitus (1)
Corneal Diseases (4) · Eye Diseases (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Corneal Dystrophies, Hereditary (3) · Eye Diseases, Hereditary (3) · Genetic Diseases, Inborn (3) · Eye Manifestations (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Postoperative Complications (2) · Signs and Symptoms (2) · Endocrine System Diseases (1) · Glucose Metabolism Disorders (1) · Metabolic Diseases (1) · Nutritional and Metabolic Diseases (1)
Calcium Dobesilate (1) · Dexamethasone (1) · Sodium Chloride (1)
Case Western Reserve University (2) · Cairo University (1) · Emmecell (1)
United States (3)
Jonathan Lass, MD (2) · Ahmed A Abdel Azim, MD (1) · Ahmed A. Dahab, MD (1) · Ayman GA Elnahry, Msc (1) · Noelia Kunzevitzky, PhD (1) · Shaimaa A Arfeen, MD (1)
PMID 39808526, PMID 41105094, PMID 41105099, PMID 42521031, PMID 42848388
1UG1EY030030-01A1 (1), 1UG1EY030039-01A1 (1), 1UG1EY037206-01 (1), 5UG1EY030030-05 (1)