10 completed. 10 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Completed 10 |
| Phase 2 | 1 | Completed 1 |
Follow Common Variable Immunodeficiency: new trials by email Literature Review of Common Variable Immunodeficiency trials Research Report on Common Variable Immunodeficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Efficacy of CDZ173 in Patients With APDS/PASLI CDZ173, Placebo - Common Variable Immunodeficiency (CVID), APDS / PASLI | Phase 2 / Phase 3 | Completed | Novartis Pharmaceuticals | 37 | 2015-08-24 | 2022-08-10 |
| Pharmacokinetics (PK) and Safety of Subgam-VF in Primary Immunodeficiency Diseases Subgam - Primary Immune Deficiency Disorders, Common Variable Immunodeficiency | Phase 3 | Completed | Bio Products Laboratory | 38 | 2015-08-20 | 2018-09-12 |
| Bioequivalence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Gammaplex® 10 and Gammaplex® 5% in Primary Immunodeficiency Diseases Gammaplex (5%), Gammaplex 10 - Primary Immune Deficiency Disorders, Common Variable Immunodeficiency | Phase 3 | Completed | Bio Products Laboratory | 48 | 2014-02-01 | 2017-03-29 |
| Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy Human Normal Immunoglobulin for Subcutaneous Administration (IGSC) - Common Variable Immunodeficiency, X-linked Agammaglobulinemia | Phase 3 | Completed | CSL Behring | 51 | 2007-09-01 | 2011-09-01 |
| A Clinical Study of Intravenous Immunoglobulin Immune Globulin Intravenous (Human) Omr-IgG-am IGIV - Immunologic Deficiency Syndromes | Phase 3 | Completed | FFF Enterprises | 57 | 2006-11-01 | 2014-08-11 |
| Efficacy, Safety and Pharmacokinetics of Gammaplex in Primary Immunodeficiency Diseases. Gammaplex (Intravenous immunoglobulin) - Primary Immunodeficiency, Common Variable Hypogammaglobulinemia | Phase 3 | Completed | Bio Products Laboratory | 50 | 2006-01-01 | 2013-01-24 |
| Safety and Efficacy of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID) Immunoglobulins Intravenous (Human) - Agammaglobulinemia, IgG Deficiency | Phase 3 | Completed | CSL Behring | 55 | 2005-11-01 | 2012-10-26 |
| Efficacy and Safety of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID) Immunoglobulins Intravenous (Human) - Agammaglobulinemia, IgG Deficiency | Phase 3 | Completed | CSL Behring | 89 | 2004-09-01 | 2012-06-06 |
| Efficacy and Safety of Intravenous Immunoglobulin IVIG-F10 in Patients With Primary Immunodeficiencies (PID) Immunoglobulins Intravenous (Human) - Agammaglobulinemia, IgG Deficiency | Phase 3 | Completed | CSL Behring | 42 | 2004-09-01 | 2011-02-11 |
| Rapid Infusion of Immune Globulin Intravenous (Human) In Primary Immunodeficiency Patients Immune Globulin Intravenous [Human], 10% Caprylate/Chromatography Purified, Dextrose, 5% in Water - Immunologic Deficiency Syndrome, Agammaglobulinemia | Phase 3 | Completed | Grifols Therapeutics LLC | 100 | 2002-08-01 | 2009-09-25 |
Agammaglobulinemia (5) · Bruton type agammaglobulinemia (4) · Hyper-IgM Immunodeficiency Syndrome (4) · Primary Immunodeficiency Diseases (4) · IgG Deficiency (3) · Immunologic Deficiency Syndromes (2) · Wiskott-Aldrich Syndrome (2) · Activated PI3K-delta Syndrome (1) · Agammaglobulinemia, non-Bruton type (1) · Hypogammaglobulinemia, X-Linked (1) · Severe Combined Immunodeficiency (1)
Immune System Diseases (10) · Blood Protein Disorders (8) · Hematologic Diseases (8) · Hemic and Lymphatic Diseases (8) · Immunologic Deficiency Syndromes (8) · Dysgammaglobulinemia (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Genetic Diseases, Inborn (5) · Lymphatic Diseases (5) · Lymphoproliferative Disorders (5) · Blood Coagulation Disorders (2) · Blood Coagulation Disorders, Inherited (2) · Cytopenia (2) · Genetic Diseases, X-Linked (2) · Hemorrhagic Disorders (2)
Immunoglobulins, Intravenous (5) · gamma-Globulins (5) · Caprylates (1) · Glucose (1) · Hizentra (1) · Water (1) · leniolisib (1)
CSL Behring (4) · Bio Products Laboratory (3) · FFF Enterprises (1) · Grifols Therapeutics LLC (1) · Novartis Pharmaceuticals (1)
United States (7) · United Kingdom (3) · Canada (2) · Germany (2) · Italy (2) · Belarus (1) · Czechia (1) · France (1) · Hungary (1) · Ireland (1) · Netherlands (1) · Poland (1) · Romania (1) · Russia (1) · Spain (1)
Eric Wolford (2) · Akhilesh Chouksey, MD (1) · Chaim Roifman, MD (1) · Daniel Suez, MD (1) · Don McNeil, MD (1) · Erwin Gelfand, MD (1) · Eyal Grunebaum, MD (1) · Gordan L Sussman, MD (1) · Isaac R Melamed, MD (1) · James Moy, MD (1) · Koneti V Rao, MD (1) · Mark Stein, MD (1) · Melvin Berger, MD (1)
PMID 36818468, PMID 17479360, PMID 18814020, PMID 20217199, PMID 21674136, PMID 21705277, PMID 28972011, PMID 36399712, PMID 39271296, PMID 39919133, PMID 41091701, PMID 41773292
2014 (1)