7 recruiting, 1 active not recruiting. 8 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Recruiting 7, Active not recruiting 1 |
Follow Clonal Cytopenia of Undetermined Significance: new trials by email Literature Review of Clonal Cytopenia of Undetermined Significance trials Research Report on Clonal Cytopenia of Undetermined Significance
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Research On Nicotinamide Riboside Supplement Support in MDS (ROSS Trial) Nicotinamide Riboside, Pterostilbene - Clonal Cytopenia of Undetermined Significance, Myelodysplastic Syndrome | Phase 2 | Recruiting | University of Colorado, Denver | 10 | 2026-05-20 | 2026-06-03 |
| A Phase 2 Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic/Syndromes/Chronic Myelomonocytic Leukemia. Olutasidenib - Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 15 | 2024-12-10 | 2026-09-11 |
| Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH2A Decentralized Trial Enasidenib - Clonal Cytopenia of Undetermined Significance, CCUS Clonal Cytopenia of Undetermined Significance | Phase 2 | Recruiting | Washington University School of Medicine | 15 | 2024-10-10 | 2026-08-10 |
| Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Clonal Cytopenia of Undetermined Significance, Essential Thrombocythemia | Phase 2 | Recruiting | University of Southern California | 30 | 2024-03-01 | 2026-03-27 |
| Statins in Patients With Clonal Cytopenia of Undetermined Significance (CCUS) and Myelodysplastic Syndromes (MDS) Atorvastatin, Rosuvastatin - Clonal Cytopenia of Undetermined Significance, Myelodysplastic Syndromes | Phase 2 | Recruiting | Washington University School of Medicine | 16 | 2024-02-19 | 2026-07-23 |
| Canakinumab for the Prevention of Progression to Cancer in Patients With Clonal Cytopenias of Unknown Significance, IMPACT Study Biospecimen Collection, Bone Marrow Aspiration and Biopsy, Canakinumab - Clonal Cytopenia of Undetermined Significance | Phase 2 | Recruiting | Uma Borate | 110 | 2023-02-06 | 2026-01-02 |
| Ivosidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH1 Ivosidenib - Clonal Cytopenia of Undetermined Significance | Phase 2 | Active not recruiting | Washington University School of Medicine | 20 | 2022-04-01 | 2026-08-12 |
| Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia Ascorbic Acid, Carboplatin, Cisplatin - Clonal Cytopenia of Undetermined Significance, High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements | Phase 2 | Recruiting | Mayo Clinic | 80 | 2018-03-23 | 2026-09-28 |
Myelodysplastic Syndromes (4) · Leukemia, Myelomonocytic, Chronic (2) · Hodgkin Disease (1) · Inflammation (1) · Lymphoma (1) · Lymphoma, Large B-Cell, Diffuse (1) · Polycythemia Vera (1) · Primary Myelofibrosis (1) · Thrombocythemia, Essential (1)
Bone Marrow Diseases (5) · Hematologic Diseases (5) · Hemic and Lymphatic Diseases (5) · Neoplasms (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Chronic Disease (2) · Disease Attributes (2) · Leukemia (2) · Leukemia, Myeloid (2) · Myelodysplastic-Myeloproliferative Diseases (2) · Neoplasms by Histologic Type (2) · Blood Coagulation Disorders (1) · Blood Platelet Disorders (1) · Bone Marrow Neoplasms (1)
Biopsy (3) · Specimen Handling (3) · X-Rays (2) · 1,2-diaminocyclohexaneplatinum II citrate (1) · Ascorbic Acid (1) · Atorvastatin (1) · Biopsy, Large-Core Needle (1) · Biopsy, Needle (1) · CT-P10 (1) · Calcium Dobesilate (1) · Carboplatin (1) · Central Venous Catheters (1) · Cisplatin (1) · Curcumin (1) · Cytarabine (1)
Washington University School of Medicine (3) · M.D. Anderson Cancer Center (1) · Mayo Clinic (1) · Uma Borate (1) · University of Colorado, Denver (1) · University of Southern California (1)
United States (8)
Amber Afzal, M.D., MSCI (1) · Casey L O'Connell, MD (1) · Giulia Petrone, M.D. (1) · Kelly Bolton, M.D., Ph.D. (1) · Kelly Chien, MD (1) · Maria Amaya, PhD MD (1) · Thomas E Witzig, M.D. (1) · Uma M Borate, MD, MS (1)
P30CA014089 (1), P50CA097274 (1)