9 completed, 4 unknown, 1 recruiting. 14 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 14 | Completed 9, Unknown 4, Recruiting 1 |
Follow Chronic Urticaria: new trials by email Literature Review of Chronic Urticaria trials Research Report on Chronic Urticaria
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Histamine Human Immunoglobulin in the Treatment of Chronic Spontaneous Urticaria (CSU) human histaglobulin, placebo, Loratadine 10 Mg - Chronic Spontaneous Urticaria | Phase 4 | Unknown | Hangzhou Grand Biologic Pharmaceutical, Inc. | 252 | 2024-03-31 | 2024-02-09 |
| Extending Omalizumab Treatment Intervals in Patients With Chronic Spontaneous Urticaria omalizumab 300 mg every four weeks, omalizumab 300 mg every six weeks - Chronic Spontaneous Urticaria, Chronic Urticaria, Idiopathic | Phase 4 | Recruiting | Simon Francis Thomsen | 40 | 2024-01-12 | 2025-09-19 |
| Molecular Endotypes of Chronic Idiopathic Urticaria Omalizumab - Chronic Urticaria, Idiopathic | Phase 4 | Unknown | University of Colorado, Denver | 15 | 2022-01-01 | 2024-08-15 |
| Tranexamic Acid and Spontaneous Chronic Urticaria association of levocetirizine and tranexamic acid, Levocetirizine only - Chronic Spontaneous Urticaria | Phase 4 | Unknown | University Hospital, Grenoble | 80 | 2019-12-10 | 2021-04-28 |
| Role of Immunoglobulin E (IgE) Bearing Cells in Chronic Idiopathic Urticaria (CIU) Omalizumab - Urticaria Chronic | Phase 4 | Completed | Johns Hopkins University | 18 | 2017-10-06 | 2021-06-14 |
| Treatment of Chronic Urticarial Unresponsive to H1-antihistamines With an Anti-IL5Ralpha Monoclonal Antibody benralizumab, placebo - Chronic Idiopathic Urticaria | Phase 4 | Completed | Jonathan A. Bernstein, MD | 12 | 2017-09-12 | 2019-07-10 |
| Omalizumab in Chronic Spontaneous Urticaria Patients Non Responding to Initial Standard antihistaminE Treatment OMALIZUMAB - CHRONIC SPONTANEOUS URTICARIA | Phase 4 | Completed | Novartis Pharmaceuticals | 136 | 2015-04-22 | 2020-02-25 |
| Effect of Omalizumab (Xolair) on Basophils in Patients With Chronic Idiopathic Urticaria Omalizumab - Chronic Urticaria | Phase 4 | Completed | University of Colorado, Denver | 10 | 2013-04-01 | 2020-12-04 |
| Levocetirizine Plus Bed-Time Hydroxyzine in the Management of Corticodependent Chronic Urticaria Versus Levocetirizine Alone in High Doses Levocetirizine, Levocetirizine plus Hydroxyzine - Chronic Urticaria | Phase 4 | Completed | Association Asthma, Bulgaria | 24 | 2011-03-01 | 2013-07-17 |
| Safety Study of Levocetirizine and Fexofenadine Levocetirizine Oral Tablet, Fexofenadine 60 Mg Oral Tablet, Placebo Oral Tablet - Pruritus, Chronic Urticaria | Phase 4 | Completed | Charite University, Berlin, Germany | 18 | 2011-02-01 | 2019-10-04 |
| Study for the Treatment of Chronic Idiopathic Urticaria With High Doses of AERIUS (Desloratadine) (Study P04849) 5-mg Desloratadine, 10-mg Desloratadine, 20-mg Desloratadine - Chronic Idiopathic Urticaria | Phase 4 | Completed | Organon and Co | 314 | 2007-09-01 | 2024-05-23 |
| The Efficacy and Safety of Desloratadine With Levocetirizine in Treatment of Chronic Idiopathic Urticaria Denosin® and Xyzal® - Chronic Idiopathic Urticaria, Urticaria | Phase 4 | Unknown | Lotus Pharmaceutical | 60 | 2006-01-01 | 2006-06-30 |
| CUTE (Chronic Urticaria Treatment Evaluation) Levocetirizine, Desloratadine - Chronic Idiopathic Urticaria | Phase 4 | Completed | UCB Pharma | 886 | 2005-12-01 | 2011-08-31 |
| A Comparison of Aerius Continuous Treatment Versus Aerius PRN for Chronic Idiopathic Urticaria (Study P03147) desloratadine - Urticaria, Chronic Idiopathic Urticaria | Phase 4 | Completed | Organon and Co | 129 | 2003-04-01 | 2024-08-15 |
Urticaria (4) · Pruritus (1) · Rhinitis, Allergic (1)
Chronic Disease (14) · Disease Attributes (14) · Hypersensitivity (14) · Hypersensitivity, Immediate (14) · Immune System Diseases (14) · Pathologic Processes (14) · Pathological Conditions, Signs and Symptoms (14) · Skin Diseases (14) · Skin Diseases, Vascular (14) · Skin and Connective Tissue Diseases (14) · Urticaria (10) · Nose Diseases (1) · Otorhinolaryngologic Diseases (1) · Respiratory Hypersensitivity (1) · Respiratory Tract Diseases (1)
Omalizumab (5) · levocetirizine (4) · desloratadine (3) · Hydroxyzine (1) · Loratadine (1) · Tablets (1) · Tranexamic Acid (1) · benralizumab (1) · fexofenadine (1)
Organon and Co (2) · University of Colorado, Denver (2) · Association Asthma, Bulgaria (1) · Charite University, Berlin, Germany (1) · Hangzhou Grand Biologic Pharmaceutical, Inc. (1) · Johns Hopkins University (1) · Jonathan A. Bernstein, MD (1) · Lotus Pharmaceutical (1) · Novartis Pharmaceuticals (1) · Simon Francis Thomsen (1) · UCB Pharma (1) · University Hospital, Grenoble (1)
United States (4) · France (3) · Germany (2) · Belgium (1) · Bulgaria (1) · Denmark (1) · Italy (1) · Malaysia (1) · Romania (1) · South Africa (1) · Spain (1) · Taiwan (1) · United Kingdom (1)
PMID 19133920, PMID 23147964, PMID 29671921, PMID 33713769, PMID 39762098
R01AI116658 (1)