5 completed, 1 active not recruiting, 1 terminated, 1 unknown. 5 Phase 1, 5 Phase 2, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 2, Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 5 | Completed 3, Terminated 1, Unknown 1 |
| Not applicable | 1 | Active not recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow Chronic Myocardial Ischemia: new trials by email Literature Review of Chronic Myocardial Ischemia trials Research Report on Chronic Myocardial Ischemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CardiAMP Cell Therapy Chronic Myocardial Ischemia Trial CardiAMP Cell Therapy System, Sham Treatment - Refractory Angina, Chronic Myocardial Ischemia | Not applicable | Active not recruiting | BioCardia, Inc. | 343 | 2021-06-30 | 2026-01-06 |
| Administration of Mesenchymal Stem Cells in Patients With Chronic Ischemic Cardiomyopathy (MESAMI2) Autologous MSC from bone marrow, Placebo comparator - Chronic Myocardial Ischemia | Phase 2 | Completed | University Hospital, Toulouse | 39 | 2016-02-19 | 2023-03-30 |
| Bone Marrow-derived Mesenchymal Stem Cells (MSC) Administration in Weaning From Left Ventricular Assist Device Autologous mesenchymal stem cells - Chronic Myocardial Ischemia | Phase 1 | Withdrawn | University Hospital, Toulouse | 2015-06-01 | 2018-01-05 | |
| Phase I Trial of Endocavitary Injection of Bone Marrow Derived CD133+ Cells in Ischemic Refractory Cardiomyopathy (RECARDIO Trial) Autologous bone marrow derived-CD133+ cells - Chronic Myocardial Ischemia | Phase 1 | Completed | Centro Cardiologico Monzino | 12 | 2013-12-01 | 2022-03-22 |
| Efficacy and Safety of Targeted Intramyocardial Delivery of Auto CD34+ Stem Cells for Improving Exercise Capacity in Subjects With Refractory Angina Auto-CD34+ cells, Placebo: Diluent used to suspend Auto-CD34+ cells, Standard of care - Chronic Myocardial Ischemia, Refractory Angina Pectoris | Phase 3 | Completed | Lisata Therapeutics, Inc. | 291 | 2012-04-01 | 2018-12-19 |
| Intracoronary Infusion of Bone Marrow Mononuclear Cells in Patients With Previous Myocardial Infarction. Bone marrow mononuclear cells - Chronic Myocardial Ischemia | Phase 2 | Completed | Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud | 20 | 2010-12-01 | 2015-06-30 |
| Cell Therapy in Patients With Chronic Ischemic Heart Disease Undergoing Cardiac Surgery bone marrow mononuclear cells injection, placebo intramyocardial injection - Old Myocardial Infarction, Chronic Myocardial Ischemia | Phase 1 / Phase 2 | Unknown | Chinese PLA General Hospital | 60 | 2010-12-01 | 2011-01-12 |
| Mesenchymal Stem Cells and Myocardial Ischemia Mesenchymal stem cells - Chronic Myocardial Ischemia, Left Ventricular Dysfunction | Phase 1 / Phase 2 | Completed | University Hospital, Toulouse | 10 | 2009-10-01 | 2014-09-19 |
| Stem Cell Study for Patients With Heart Disease Autologous peripheral blood CD34 positive cell therapy - Chest Pain, Chronic Myocardial Ischemia | Phase 1 / Phase 2 | Terminated | Foundation for Biomedical Research and Innovation | 1 | 2005-09-01 | 2011-06-22 |
Angina Pectoris (3) · Coronary Artery Disease (2) · Ventricular Dysfunction, Left (2) · Chest Pain (1) · Heart Diseases (1) · Myocardial Infarction (1) · Pain (1) · Vascular Diseases (1)
Cardiovascular Diseases (5) · Heart Diseases (4) · Myocardial Ischemia (4) · Neurologic Manifestations (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Vascular Diseases (3) · Arterial Occlusive Diseases (2) · Arteriosclerosis (2) · Chest Pain (2) · Coronary Disease (2) · Pain (2) · Ventricular Dysfunction (2) · Infarction (1) · Ischemia (1)
Serum Albumin, Human (1) · Standard of Care (1)
University Hospital, Toulouse (3) · Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud (1) · BioCardia, Inc. (1) · Centro Cardiologico Monzino (1) · Chinese PLA General Hospital (1) · Foundation for Biomedical Research and Innovation (1) · Lisata Therapeutics, Inc. (1)
France (3) · United States (2) · China (1) · Italy (1) · Japan (1) · Spain (1)
Amish Raval, MD (1) · Gao Changqing, MD (1) · Giulio Pompilio, MD PhD (1) · Inmaculada Herrera, MD, PhD (1) · Takayuki Asahara, M.D. (1)
PMID 23708155, PMID 26901787, PMID 27491607, PMID 30217223
2009 (1)