6 completed, 3 terminated, 2 unknown, 1 recruiting. 12 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 12 | Completed 6, Terminated 3, Unknown 2, Recruiting 1 |
Follow Chronic Kidney Failure: new trials by email Literature Review of Chronic Kidney Failure trials Research Report on Chronic Kidney Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Belatacept as a Replacement for CNIs 3 to 12 Months Post-transplantation in Patients With Early Graft Dysfunction Belatacept 250 Milligram Intravenous Powder for Solution - Chronic Kidney Failure | Phase 3 | Recruiting | Nantes University Hospital | 30 | 2024-05-03 | 2024-05-09 |
| A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery Sirolimus - Complication of Renal Dialysis, End Stage Renal Disease | Phase 3 | Completed | Vascular Therapies, Inc. | 136 | 2022-08-26 | 2026-10-06 |
| CNI Transient Replacement by Belatacept From 3 to 12 Months Post Transplantation in Patients With Early Graft Dysfunction Belatacept 250 Milligram Intravenous Powder for Solution - Chronic Kidney Failure | Phase 3 | Unknown | Nantes University Hospital | 48 | 2020-09-01 | 2020-03-31 |
| Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes Sirolimus, AV Fistula Surgery, Sirolimus-eluting Collagen Implant (SeCI) - Complication of Renal Dialysis, End Stage Renal Disease | Phase 3 | Completed | Vascular Therapies, Inc. | 269 | 2015-11-01 | 2025-10-09 |
| Multimodal Therapeutic Approach in Undernourished Maintenance Hemodialysis Patients (AMERICANO) training on ergonomic bicycle, Testosterone, Oral nutritional supplementation - Chronic Kidney Failure | Phase 3 | Unknown | University Hospital, Clermont-Ferrand | 120 | 2013-12-01 | 2016-07-29 |
| Effect of N-acetylcysteine (NAC) on Hydrogen Sulfide (H2S) in Chronic Kidney Disease (CKD) N-acetylcysteine - Chronic Kidney Disease, Chronic Kidney Failure | Phase 3 | Completed | A.C. Abrahams | 28 | 2011-07-01 | 2012-10-26 |
| Phase III Study to Investigate the Safety and Efficacy of Fermagate and Lanthanum Carbonate Magnesium iron hydroxycarbonate, Lanthanum carbonate, Placebo - Chronic Kidney Failure | Phase 3 | Terminated | Ineos Healthcare Limited | 657 | 2009-07-01 | 2010-10-19 |
| Phase III Study to Investigate the Safety and Efficacy of Fermagate and Sevelamer Hydrochloride Fermagate, Sevelamer hydrochloride - Chronic Kidney Failure | Phase 3 | Terminated | Ineos Healthcare Limited | 1000 | 2009-07-01 | 2010-10-19 |
| Clinical Evaluation of Low Sodium Peritoneal Dialysis (PD) Solution on Hypertensive Patients Treated With PD Solution for Peritoneal Dialysis - Chronic Kidney Failure | Phase 3 | Completed | Fresenius Medical Care Deutschland GmbH | 140 | 2008-10-01 | 2015-02-27 |
| Evaluation of a Third and Fourth Dose of StaphVAX® in Adults With End-Stage Renal Disease Staph aureus types 5 and 8 conjugate vaccine, placebo - Staphylococcal Infections, Chronic Kidney Failure | Phase 3 | Terminated | Nabi Biopharmaceuticals | 99 | 2005-08-01 | 2008-01-04 |
| Evaluation of Manufacturing Lot of StaphVAX S. aureus Type 5 & 8 Capsular Polysaccharide Vaccine - Staphylococcal Infections, Chronic Kidney Failure | Phase 3 | Completed | Nabi Biopharmaceuticals | 65 | 2005-03-01 | 2008-01-04 |
| Belatacept Evaluation of Nephroprotection and Efficacy as First-line Immunosuppression (BENEFIT) Cyclosporine (CsA), Belatacept LI (less intensive), Belatacept MI (more intensive) - Kidney Transplantation, Chronic Kidney Failure | Phase 3 | Completed | Bristol-Myers Squibb | 738 | 2005-03-01 | 2016-08-19 |
Kidney Failure, Chronic (12) · Arteriovenous Fistula (2) · Hyperphosphatemia (2) · Renal Insufficiency, Chronic (2) · Staphylococcal Infections (2) · Hypertension (1) · Motor Activity (1)
Chronic Disease (12) · Disease Attributes (12) · Female Urogenital Diseases (12) · Female Urogenital Diseases and Pregnancy Complications (12) · Kidney Diseases (12) · Male Urogenital Diseases (12) · Pathologic Processes (12) · Pathological Conditions, Signs and Symptoms (12) · Renal Insufficiency (12) · Urogenital Diseases (12) · Urologic Diseases (12) · Renal Insufficiency, Chronic (10) · Cardiovascular Diseases (3) · Vascular Diseases (3) · Arteriovenous Malformations (2)
Sirolimus (2) · Solutions (2) · StaphVax (2) · iron-magnesium hydroxycarbonate (2) · Acetylcysteine (1) · Cyclosporine (1) · Dialysis Solutions (1) · Dietary Supplements (1) · Fatty Acids, Omega-3 (1) · Sevelamer (1) · Testosterone (1) · lanthanum carbonate (1)
Ineos Healthcare Limited (2) · Nabi Biopharmaceuticals (2) · Nantes University Hospital (2) · Vascular Therapies, Inc. (2) · A.C. Abrahams (1) · Bristol-Myers Squibb (1) · Fresenius Medical Care Deutschland GmbH (1) · University Hospital, Clermont-Ferrand (1)
United States (7) · France (6) · Brazil (3) · Germany (3) · South Africa (3) · United Kingdom (3) · Australia (2) · Belgium (2) · Canada (2) · Czechia (2) · Hungary (2) · Israel (2) · Italy (2) · Mexico (2) · Poland (2)
Matt Hohenboken, MD, PhD (2) · Sriram Iyer, MD (2) · A C Abrahams, MD (1) · Bengt Rippe, Prof (1) · M C Verhaar, MD, PhD (1) · Simon Davies, Prof (1) · Vedat Schwenger, Dr (1)
PMID 26718625, PMID 21992533, PMID 24831918, PMID 26816011, PMID 27355541, PMID 32390133
2008 (2)