6 completed, 2 unknown, 1 recruiting, 1 terminated. 10 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 10 | Completed 6, Unknown 2, Recruiting 1, Terminated 1 |
Follow Chronic Insomnia: new trials by email Literature Review of Chronic Insomnia trials Research Report on Chronic Insomnia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for Insomnia Sleep Hygiene Education, Melatonin IR, 3 mg, Melatonin IR, 5 mg - Insomnia, Insomnia Disorder | Phase 4 | Recruiting | University of Pennsylvania | 1200 | 2026-05-01 | 2026-09-16 |
| CBT-I or Zolpidem/Trazodone for Insomnia Zolpidem, Internet Cognitive Behavioral Therapy for Insomnia (CBT-I), Trazodone - Chronic Insomnia | Phase 4 | Completed | California Pacific Medical Center Research Institute | 155 | 2022-02-25 | 2025-02-24 |
| Xuefu-Zhuyu Capsule for the Treatment of "Qizhi Xueyu Zheng" (Qi Stagnation and Blood Stasis Syndrome) Xuefu-Zhuyu Capsule, placebo, conventional therapy - Chinese Medicine, Stable Coronary Heart Disease | Phase 4 | Unknown | Zhong Wang | 720 | 2019-12-31 | 2022-11-15 |
| Impact of Suvorexant on Sympathetic Nerve Activity and Baroreflex Function in Chronic Insomnia Suvorexant, Placebo - Chronic Insomnia | Phase 4 | Unknown | Montana State University | 34 | 2019-04-18 | 2021-10-07 |
| The Study of Combination Use of Melatonin Receptor Agonist for Dose Reduction or Interruptions of Benzodiazepine (BZD) and Non-BZD Hypnotics on Chronic Insomnia Ramelteon 8mg, Placebo - Chronic Insomnia | Phase 4 | Completed | Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan | 17 | 2018-02-06 | 2024-11-20 |
| Safety and Efficacy of Chronic Hypnotic Use 2 placebo, Zolpidem CR, Eszopiclone - Chronic Insomnia | Phase 4 | Completed | Henry Ford Health System | 41 | 2015-08-05 | 2024-03-29 |
| Cognitive-Behavior Therapy for Insomnia Cognitive-Behavior Therapy, Behavior Therapy, Cognitive Therapy - Chronic Insomnia | Phase 4 | Completed | Laval University | 186 | 2008-04-01 | 2013-07-02 |
| Facilitation of Zolpidem (≥10 mg) Discontinuation Through Use of Ramelteon in Subjects With Chronic Insomnia Ramelteon and zolpidem, Placebo and zolpidem - Chronic Insomnia | Phase 4 | Completed | Takeda | 135 | 2007-04-01 | 2010-07-20 |
| Subjective Efficacy of Ramelteon on Sleep in Adults With Chronic Insomnia. Ramelteon, Placebo - Chronic Insomnia | Phase 4 | Completed | Takeda | 552 | 2006-10-01 | 2016-06-28 |
| Treating Chronic Insomnia in Breast Cancer Patients Placebo, Ramelteon - Chronic Insomnia | Phase 4 | Terminated | Accelerated Community Oncology Research Network | 16 | 2006-08-01 | 2011-08-22 |
Sleep Initiation and Maintenance Disorders (10) · Endometriosis (1) · Headache (1) · Parasomnias (1) · Sleep Wake Disorders (1)
Dyssomnias (10) · Mental Disorders (10) · Nervous System Diseases (10) · Sleep Disorders, Intrinsic (10) · Sleep Wake Disorders (9) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Genital Diseases (1) · Genital Diseases, Female (1) · Pain (1) · Urogenital Diseases (1)
ramelteon (4) · Zolpidem (3) · Trazodone (2) · Behavior Therapy (1) · Cognitive Behavioral Therapy (1) · Diphenhydramine (1) · Doxepin (1) · Eszopiclone (1) · Xue-Fu-Zhu-Yu decoction (1) · suvorexant (1)
Takeda (2) · Accelerated Community Oncology Research Network (1) · California Pacific Medical Center Research Institute (1) · Henry Ford Health System (1) · Laval University (1) · Montana State University (1) · Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan (1) · University of Pennsylvania (1) · Zhong Wang (1)
United States (8) · Canada (1) · China (1) · Japan (1)
Charles M. Morin, PhD (1) · Daniel J. Buysse, MD (1) · Edward J. Stepanski, Ph.D. (1) · Jason Carter, PhD (1) · Katie L. Stone, PhD (1) · Michael L Perlis, PhD (1) · Qing-Quan Liu, Prof. (1) · Timothy A Roehrs, PhD (1) · Yuichi Inoue, MD, Ph.D. (1) · Zhong Wang, M.D. (1)