83 completed, 32 unknown, 11 recruiting, 7 active not recruiting. 39 Not applicable, 35 Phase 2, 20 Phase 3, 13 Phase 1, 8 Phase 4.
Follow Cervical Intraepithelial Neoplasia: new trials by email Literature Review of Cervical Intraepithelial Neoplasia trials Research Report on Cervical Intraepithelial Neoplasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hexaminolevulinate Photodynamic Therapy (HAL-PDT) With Deferred Surgery Versus Surgery for High-grade Squamous Intraepithelial Lesions (HSIL) Loop Electrosurgical Excision Procedure (LEEP) or Cold Knife Conization (CKC), HAL 5% with illumination - Cervical Intraepithelial Neoplasia, Papillomavirus Infections | Phase 2 | Not yet recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 230 | 2026-07-01 | 2026-07-09 |
| PRIORITY Study in Cervical Cancer Cervical Cancer, Cervical Intraepithelial Neoplasia | Not yet recruiting | Pontificia Universidad Catolica de Chile | 700 | 2026-06-30 | 2026-05-18 | |
| Point of Care - Triage and Treatment for Cervical Pre-cancer IRIS™ Thermal Ablation Device - Cervical Precancer, Cervical Intraepithelial Neoplasia | Not applicable | Recruiting | Basic Health International, Inc. | 5000 | 2026-01-01 | 2026-08-28 |
| Human Papillomavirus Self-sampling for Enhancing Cervical Screening During the War in Ukraine HPV Self-Sampling Kit - Cervical Cancer, Cervical Cancer Screening | Not applicable | Recruiting | Karolinska Institutet | 1000 | 2025-04-01 | 2025-12-18 |
| Study on Novel Strategies for Cervical Cancer Screening Using Photoelectric Detection and Epigenetic Procotol photoelectric detection - Cervical Cancer, Cervical Intraepithelial Neoplasia | Not yet recruiting | Peking Union Medical College Hospital | 4200 | 2025-03-15 | 2025-03-10 | |
| Validation of a Lab-free Low-cost Screening Test for Prevention of Cervical Cancer HPV Test, EVA System, Visual Inspection with Acetic Acid (VIA) - Human Papillomavirus (HPV), Cervical Intraepithelial Neoplasia | Not applicable | Recruiting | DL Analytics | 10000 | 2025-02-12 | 2026-01-29 |
| A Novel, Low-Cost, Handheld 3D Imaging System for Improved Screening for Cervical Neoplasia in Resource-Limited Settings CervImage device - Cervical Intraepithelial Neoplasia | Not applicable | Active not recruiting | Carilion Clinic | 18 | 2025-01-16 | 2026-03-18 |
| Fenofibrate in Patients With Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma Fenofibrate, Cervical Conization, Hysterectomy - Cervical Intraepithelial Neoplasia, Invasive Cervical Cancer | Phase 1 | Recruiting | Lindsay Ferguson, MD | 24 | 2024-11-20 | 2026-07-27 |
| Comparisons of the Effects and Clinical Outcomes of CH2 Vaginal Gel Versus Placebo on CIN1 CH2 vaginal gel, Placebo hyaluronic acid gel - Cervical Intraepithelial Neoplasia, Human Papillomavirus | Not applicable | Active not recruiting | National Taiwan University Hospital | 50 | 2024-09-30 | 2025-11-19 |
| Cervical Intraepithelial Neoplasia Screening Using Liquid-Based Pap Smear Among Egyptian Women Liquid-Based Pap Smear (LBC) - Cervical Intraepithelial Neoplasia, Cervical Cancer (Early Detection) | Completed | Kasr El Aini Hospital | 984 | 2024-09-01 | 2025-11-28 | |
| Cervical Cytology DNA Methylation for Cervical Cancer Screening human PAX1 and JAM3 gene methylation assays (PAX1m/JAM3m) - Cervical Cancer, DNA Methylation | Unknown | Lei Li | 30000 | 2024-09-01 | 2024-08-19 | |
| Long-Term Immune Persistence After Bivalent HPV Vaccination in Females From Study 311-HPV-1005 Recombinant Human Papillomavirus Bivalent (Types 16 and 18) Vaccine (Pichia pastoris) - Human Papillomavirus Infection, Cervical Intraepithelial Neoplasia | Enrolling by invitation | Shanghai Zerun Biotechnology Co.,Ltd | 486 | 2024-08-30 | 2026-09-22 | |
| Efficacy of Topical 85% TCA in the Treatment of LSIL After Low-grade Abnormality of Screening Test: a Randomized Controlled Trial 85%TCA topical application, 3% acetic acid - Cervical Intraepithelial Neoplasia, Trichloroacetic Acid | Phase 2 | Unknown | Department of Medical Services Ministry of Public Health of Thailand | 44 | 2024-08-01 | 2024-11-14 |
| A Multicenter Randomized Controlled Study of Photoelectric Detection in Cervical Cancer Screening Detection of Cervical Lesions by Fluorescence Photoelectric Image - Uterine Cervical Cancer, Cervical Intraepithelial Neoplasia | Not applicable | Unknown | Lei Li | 4200 | 2024-08-01 | 2024-08-15 |
| Cervical Cancer Screening of Postmenopausal Women in Low- and Middle-income Countries Using HPV Self-sampling and Triage by Genotyping and Cytology Vaginal specimens for HPV test will be collected by participants themselves using flocked swabs after explanations by co-investigators. - Cervical Cancer Screening, HPV Infections | Completed | University Hospital, Geneva | 500 | 2024-06-01 | 2026-01-21 | |
| Long-term Effectiveness and Immuno-persistence Study of a Recombinant HPV 16/18 Bivalent Vaccine in Preadolescent Girls Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli), No intervention - Cervical Intraepithelial Neoplasia, Cervical Cancer | Active not recruiting | Xiamen University | 2188 | 2024-02-20 | 2025-07-31 | |
| Cervical Cancer Screening Based on First-void Urine Self-sampling to Reach un(Der)-Screened Women: ScreenUrSelf Trial Colli-Pee Small Volumes, Evalyn Brush - Cervix Cancer, Cervical Intraepithelial Neoplasia | Not applicable | Active not recruiting | Universiteit Antwerpen | 48000 | 2023-05-25 | 2025-06-13 |
| Dry Run of the ScreenUrSelf Trial Colli-Pee Small Volumes, Evalyn Brush - Cervical Cancer, Cervical Intraepithelial Neoplasia | Not applicable | Completed | Universiteit Antwerpen | 38 | 2023-04-10 | 2023-08-18 |
| Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV Human papillomavirus 9-valent vaccine, recombinant, human papillomavirus vaccine, recombinant - Papillomavirus Vaccines, Human Immunodeficiency Virus | Phase 4 | Recruiting | Louisiana State University Health Sciences Center in New Orleans | 250 | 2022-11-30 | 2025-04-18 |
| Diagnostic Cervical Conization for Persistent Infection or Integration of HPV diagnostic cervical conization - Human Papilloma Virus Infection, Human Papilloma Virus Integration | Not applicable | Not yet recruiting | Tongji Hospital | 250 | 2022-10-01 | 2022-09-08 |
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Uterine Cervical Dysplasia (150) · Uterine Cervical Neoplasms (57) · Papillomavirus Infections (22) · Persistent Infection (9) · Squamous Intraepithelial Lesions (9) · Hyperthermia (3) · Neoplasms (3) · Acquired Immunodeficiency Syndrome (2) · Condylomata Acuminata (2) · Genital Diseases, Female (2) · Genital Neoplasms, Female (2) · Infections (2) · Oropharyngeal Neoplasms (2) · Squamous Intraepithelial Lesions of the Cervix (2) · Uterine Diseases (2)
Female Urogenital Diseases (150) · Female Urogenital Diseases and Pregnancy Complications (149) · Genital Diseases (149) · Precancerous Conditions (149) · Urogenital Diseases (149) · Uterine Cervical Diseases (149) · Genital Diseases, Female (148) · Uterine Diseases (148) · Neoplasms (147) · Neoplasms by Site (58) · Urogenital Neoplasms (58) · Genital Neoplasms, Female (57) · Uterine Neoplasms (56) · Pathological Conditions, Signs and Symptoms (45) · Pathologic Processes (33)
Imiquimod (8) · Conization (7) · Vaccines (7) · Cryotherapy (4) · Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18 (4) · Papillomavirus Vaccines (4) · human papillomavirus vaccine, L1 type 16, 18 (4) · Acetic Acid (3) · Colposcopy (3) · 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone (2) · Biopsy (2) · Cisplatin (2) · GX-188 vaccine (2) · Human Papillomavirus DNA Tests (2) · Human Papillomavirus Recombinant Vaccine nonavalent (2)
GlaxoSmithKline (8) · National Cancer Institute (NCI) (8) · Jun Zhang (5) · Lei Li (5) · Barretos Cancer Hospital (4) · Universiteit Antwerpen (4) · Xiamen University (4) · Huazhong University of Science and Technology (3) · Medical University of Vienna (3) · Preventive Oncology International, Inc. (3) · Shanghai Zerun Biotechnology Co.,Ltd (3) · The Cleveland Clinic (3) · Antiva Biosciences (2) · BioLeaders Corporation (2) · Chang Gung Memorial Hospital (2)
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Ting Wu, Ph. D. (6) · Lei Li, M.D. (5) · Pierre Van Damme, MD, PhD (4) · Jerome L Belinson, MD (3) · Miriam Cremer, MD (3) · Yuemei Hu, Bachelor (3) · Alex Vorsters, Ir, PhD (2) · Beihua Kong, MD (2) · Chi-Heum Cho, MD, PhD (2) · Cynthia J Goldberg, MD (2) · Ding Ma, MD, PhD (2) · Jae-Kwan Lee, MD, PhD (2) · Jong Sup Park, MD, PhD (2) · Jun Zhang, Master (2)
PMID 22914404, PMID 24435414, PMID 28173776, PMID 10451482, PMID 10764464, PMID 10796771, PMID 14990651, PMID 15888991, PMID 16150255, PMID 16232104, PMID 16264159, PMID 1731281, PMID 17354241, PMID 17919718, PMID 17942872, PMID 17959735, PMID 19586656, PMID 19638646, PMID 19943823, PMID 20054095, PMID 20223872, PMID 20952254, PMID 21173650, PMID 21179038, PMID 21345402, PMID 21726576, PMID 22021733, PMID 22051739, PMID 22172570, PMID 22177579, PMID 22265115, PMID 22296836, PMID 22518863, PMID 22771223, PMID 23094124, PMID 23117059, PMID 23174289, PMID 23385153, PMID 23489374, PMID 23843155, PMID 24127304, PMID 24201682, PMID 24436334, PMID 24440471, PMID 24521934, PMID 24762804, PMID 24905772, PMID 25220842, PMID 25467012, PMID 25516462
2015 (2), 2008 (1), 2014 (1), 2017 (1), 2018 (1), R01CA218195 (1), R01CA285369 (1), R21CA156166 (1), R44CA247137 (1), R44CA254586 (1), UH2CA189883 (1), UH3CA189883 (1)