GX-188 vaccine: Clinical Trials

3 unknown, 2 completed. 3 Phase 2, 1 Phase 1.

By phase and status

Phase	Trials	Status
Phase 2	3	Completed 2, Unknown 1
Phase 1	1	Completed 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
The Combination of GX-188E Vaccination and Pembrolizumab in Patients With HPV 16 and/or 18+ Advanced Cervical Cancer GX-188E, KEYTRUDA® - Cervical Cancer	Phase 1 / Phase 2	Completed	Genexine, Inc.	65	2018-06-19	2025-07-30
Phase 2 Clinical Trial to Evaluate the Safety and Efficacy of Plasmid DNA Therapeutic Vaccine(GX-188E) GX-188E, Placebo - Cervical Intraepithelial Neoplasia	Phase 2	Unknown	Genexine, Inc.	134	2015-08-01	2017-07-12
Safety and Efficacy of GX-188E DNA Therapeutic Vaccine Administered by Electroporation After Observation GX-188E - Cervical Intraepithelial Neoplasia 3		Unknown	Genexine, Inc.	67	2015-03-01	2017-07-12
Dose-finding, Safety Study of Plasmid DNA Therapeutic Vaccine to Treat Cervical Intraepithelial Neoplasia GX-188E - Cervical Intraepithelial Neoplasia	Phase 2	Completed	Genexine, Inc.	72	2014-07-01	2017-07-12
Safety and Efficacy of GX-188E DNA Therapeutic Vaccine Administered by Electroporation After Observation GX-188E - Cervical Intraepithelial Neoplasia 3		Unknown	Genexine, Inc.	9	2014-02-01	2017-07-12

Conditions studied

Uterine Cervical Dysplasia (4)  ·  Papillomavirus Infections (2)  ·  Genital Diseases, Female (1)  ·  Neoplasms (1)  ·  Uterine Cervical Neoplasms (1)  ·  Uterine Diseases (1)

Sponsors

Genexine, Inc. (5)

Countries

South Korea (5)  ·  Estonia (1)  ·  Ukraine (1)

Top investigators

Aira Peri, MD (1)  ·  Chi-Heum Cho, M.D. (1)  ·  Cho Chi-heum, M.D. (1)  ·  Jae-Kwan Lee, M.D. (1)  ·  Jong-Sup Park, M.D. (1)  ·  Kersti Kukk, MD (1)  ·  Kim Tae-Jin, M.D. (1)  ·  Lee Jae-kwan, M.D. (1)  ·  Natalia Rozhkovska, MD (1)  ·  Nataliya Lutsenko, MD (1)  ·  Park Jong-Sup, M.D. (1)  ·  Sergiy Kartashov, MD (1)  ·  Soo-Young Hur, M.D (1)  ·  Tae Jin Kim, M.D. (1)  ·  Tae-Jin Kim, M.D. (1)

Results publications

PMID 33271094, PMID 38330377, PMID 39823099