CAH - Congenital Adrenal Hyperplasia: Clinical Trials

4 completed, 1 not yet recruiting, 1 recruiting. 4 Phase 2.

By phase and status

Phase	Trials	Status
Phase 2	4	Completed 4

Follow CAH - Congenital Adrenal Hyperplasia: new trials by email Literature Review of CAH - Congenital Adrenal Hyperplasia trials Research Report on CAH - Congenital Adrenal Hyperplasia

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Hydrocortisone Modified-release in Adults: Real-world Monitoring of Longitudinal Outcomes in coNgenital Adrenal hYperplasia CAH - Congenital Adrenal Hyperplasia		Not yet recruiting	IRCCS San Raffaele	100	2026-07-31	2026-06-08
Adrenal Diseases in the Population of Modena: A Clinical-Epidemiological Database of Patients Referred to the Adrenal Disorders Outpatient Clinic of the Clinical Unit of Endocrinology at the Modena University Hospital (AOU Modena) Cushing s Syndrome, Cushing Disease		Recruiting	Azienda Ospedaliero-Universitaria di Modena	2000	2026-07-09	2026-11-05
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NBI-74788 (Crinecerfont) in Pediatric Participants With Congenital Adrenal Hyperplasia Crinecerfont - CAH - Congenital Adrenal Hyperplasia	Phase 2	Completed	Neurocrine Biosciences	8	2019-12-12	2024-07-18
Study to Evaluate the Safety and Efficacy of SPR001 in Subjects With Classic Congenital Adrenal Hyperplasia SPR001 - Congenital Adrenal Hyperplasia, CAH - Congenital Adrenal Hyperplasia	Phase 2	Completed	Spruce Biosciences	11	2018-09-06	2025-04-01
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NBI-74788 in Adults With Congenital Adrenal Hyperplasia NBI-74788 - CAH - Congenital Adrenal Hyperplasia	Phase 2	Completed	Neurocrine Biosciences	18	2018-04-10	2022-05-03
Study of SPR001 in Adults With Classic Congenital Adrenal Hyperplasia SPR001 - Congenital Adrenal Hyperplasia, CAH - Congenital Adrenal Hyperplasia	Phase 2	Completed	Spruce Biosciences	24	2017-07-12	2025-10-22

Narrower conditions

Adrenal Hyperplasia, Congenital (6)  ·  ACTH Syndrome, Ectopic (1)  ·  Addison Disease (1)  ·  Adrenal Cortex Neoplasms (1)  ·  Adrenal Gland Diseases (1)  ·  Adrenal Insufficiency (1)  ·  Adrenocortical Hyperfunction (1)  ·  Adrenoleukodystrophy (1)  ·  Hyperaldosteronism (1)  ·  Myelolipoma (1)  ·  Neoplasm Metastasis (1)  ·  Paraganglioma (1)  ·  Pheochromocytoma (1)  ·  Pituitary ACTH Hypersecretion (1)

Broader conditions

Adrenogenital Syndrome (6)  ·  Congenital Abnormalities (6)  ·  Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6)  ·  Disorders of Sex Development (6)  ·  Endocrine System Diseases (6)  ·  Female Urogenital Diseases (6)  ·  Female Urogenital Diseases and Pregnancy Complications (6)  ·  Genetic Diseases, Inborn (6)  ·  Gonadal Disorders (6)  ·  Male Urogenital Diseases (6)  ·  Metabolic Diseases (6)  ·  Metabolism, Inborn Errors (6)  ·  Nutritional and Metabolic Diseases (6)  ·  Steroid Metabolism, Inborn Errors (6)  ·  Urogenital Abnormalities (6)

Interventions

crinecerfont (2)

Sponsors

Neurocrine Biosciences (2)  ·  Spruce Biosciences (2)  ·  Azienda Ospedaliero-Universitaria di Modena (1)  ·  IRCCS San Raffaele (1)

Countries

United States (4)  ·  Italy (1)

Top investigators

Andrea Giustina, MD (1)  ·  Richard Auchus, MD, PhD (1)

Results publications

PMID 34146101, PMID 26121453, PMID 27479926, PMID 32266384, PMID 37216921, PMID 37318239, PMID 38151399