8 completed, 8 recruiting, 2 not yet recruiting, 1 active not recruiting. 7 Not applicable, 6 Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Recruiting 3, Not yet recruiting 2, Completed 1, Unknown 1 |
| Phase 1 | 6 | Completed 3, Recruiting 2, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Brain Tumor, Pediatric: new trials by email Literature Review of Brain Tumor, Pediatric trials Research Report on Brain Tumor, Pediatric
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Measuring Brain Changes Following Cognitive Intervention in Pediatric Patients With Brain Tumors Online computerized cognitive training intervention focused on processing speed. - Brain Tumor, Pediatric | Not applicable | Not yet recruiting | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 300 | 2026-12-30 | 2026-11-03 |
| B7-H3.CD28Z.CART in CNS Neoplasms B7-H3.CD28Z.CART, Fludarabine, Cyclophosphamide - Central Nervous System Neoplasms, Brain Tumor | Phase 1 | Recruiting | Robbie Majzner | 70 | 2026-09-01 | 2026-09-03 |
| Irradiation in Paediatrics: Neurocognition, Neuroimaging and Evaluation of Memory and Attention Neuropsychological assessments: - Brain Tumor, Pediatric | Not applicable | Recruiting | Institut Claudius Regaud | 130 | 2025-10-21 | 2026-11-03 |
| Methylphenidate in Pediatric Brain Tumor Survivors With Cancer-related Fatigue Methylphenidate (MPH), Placebo - Brain Tumor, Pediatric, Cancer-related Fatigue | Phase 3 | Recruiting | Odense University Hospital | 50 | 2025-09-02 | 2026-11-03 |
| Intensity Modulated PrOton Therapy in Pediatric BRain Tumors (IMPORT) Intensity-modulated proton therapy (IMPT), Photon-based intensity-modulated radiation therapy (IMRT). - Brain Tumor, Pediatric | Not applicable | Recruiting | Tata Memorial Centre | 94 | 2025-08-07 | 2026-01-30 |
| Utility of PET-MRI in Surveillance of Paediatric Brain Tumours PET-MRI - Brain Tumor, Pediatric | Not applicable | Recruiting | Sheffield Children's NHS Foundation Trust | 5 | 2024-02-28 | 2026-05-06 |
| GD2-CAR T Cells for Pediatric Brain Tumours GD2-CART01 (iC9-GD2-CAR T-cells) - Brain Tumor, Pediatric, Medulloblastoma, Childhood | Phase 1 | Recruiting | Bambino Gesù Hospital and Research Institute | 54 | 2023-11-09 | 2026-09-30 |
| RE-irradiation of Diffuse MIdline Glioma paTients Re-irradiation - Diffuse Midline Glioma, H3 K27M-Mutant, Diffuse Intrinsic Pontine Glioma | Not applicable | Not yet recruiting | Copenhagen University Hospital, Rigshospitalet | 59 | 2023-10-01 | 2023-10-23 |
| RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors RRx-001, Temozolomide, Irinotecan - Brain Tumor, Recurrent, Brain Tumor, Pediatric | Phase 1 | Terminated | EpicentRx, Inc. | 2 | 2023-01-26 | 2024-10-31 |
| Genetic and Molecular Risk Profiles of Pediatric Malignant Brain Tumors in China Medulloblastoma, Central Nervous System Tumor, Pediatric | Recruiting | Beijing Tiantan Hospital | 400 | 2023-01-01 | 2023-01-05 | |
| Magrolimab in Children and Adults With Recurrent or Progressive Malignant Brain Tumors Magrolimab - Brain Cancer, Malignant Brain Tumor | Phase 1 | Completed | University of California, San Francisco | 13 | 2022-04-22 | 2025-07-09 |
| Effectiveness and Impact on the Quality of Life of Ketogenic Diet in Pediatric Patients ketogenic diet (as per clinical practice) - Drug Resistant Epilepsy, Autism Spectrum Disorder | Recruiting | Danone Nutricia SpA Società Benefit | 100 | 2022-03-01 | 2025-09-03 | |
| Acceptance and Commitment Therapy for Neuro-Oncology Wellbeing Acceptance and Commitment Therapy - Brain Tumors, Quality of Life | Not applicable | Unknown | Nottingham University Hospitals NHS Trust | 72 | 2021-03-18 | 2023-08-31 |
| Neurocognitive and Psychosocial Outcomes Among Pediatric Brain Tumor Neurocognitive tools - Brain Tumor, Pediatric | Completed | Aga Khan University | 48 | 2020-11-20 | 2026-10-29 | |
| Clinical Safety Study on 5-Aminolevulinic Acid (5-ALA) in Children and Adolescents With Brain Tumors 5-Aminolevulinic Acid Hydrochloride, Oral - Brain Tumor, Pediatric | Phase 2 | Completed | Universität Münster | 78 | 2020-09-25 | 2025-12-10 |
| HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers This study does not include an intervention. - DIPG, Brain Tumor, Pediatric, Recurrent | Completed | University of Calgary | 20 | 2020-07-02 | 2026-04-15 | |
| Study of the Bromodomain (BRD) and Extra-Terminal Domain (BET) Inhibitors BMS-986158 and BMS-986378 in Pediatric Cancer BMS-986158, BMS-986378 - Solid Tumor, Childhood, Lymphoma | Phase 1 | Completed | Dana-Farber Cancer Institute | 41 | 2019-09-27 | 2024-10-02 |
| Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors Prexasertib, Cyclophosphamide, Gemcitabine - Brain Tumor, Brain Tumor, Recurrent | Phase 1 | Completed | St. Jude Children's Research Hospital | 21 | 2019-08-08 | 2025-02-07 |
| Promotion of Well-being of Young Adult Brain Cancer Survivors Brief Internet-based Behavioral Activation Intervention - Brain Tumor, Pediatric | Not applicable | Completed | University of Wisconsin, Madison | 139 | 2019-02-13 | 2020-02-05 |
| Immunomodulation Analysis of Radiation Therapy in Pediatric Malignant Brain Tumors Brain Tumor, Pediatric | Withdrawn | Capital Medical University | 2019-02-01 | 2024-02-07 |
Showing 20 of 22. Sign in to see all of them.
Brain Neoplasms (22) · Medulloblastoma (6) · Neoplasms (5) · Central Nervous System Neoplasms (4) · Diffuse Intrinsic Pontine Glioma (3) · Ependymoma (2) · Glioma (2) · Neoplasms, Germ Cell and Embryonal (2) · Social Adjustment (2) · Autism Spectrum Disorder (1) · Brain Stem Neoplasms (1) · Depression (1) · Drug Resistant Epilepsy (1) · Hematologic Neoplasms (1) · Lymphoma (1)
Brain Diseases (22) · Central Nervous System Diseases (22) · Neoplasms by Site (22) · Nervous System Diseases (22) · Nervous System Neoplasms (22) · Central Nervous System Neoplasms (18) · Neoplasms (17) · Neoplasms by Histologic Type (8) · Neoplasms, Glandular and Epithelial (8) · Neoplasms, Nerve Tissue (8) · Neoplasms, Neuroepithelial (8) · Neuroectodermal Tumors (8) · Glioma (6) · Neoplasms, Germ Cell and Embryonal (6) · Neuroectodermal Tumors, Primitive (5)
Cyclophosphamide (2) · Acceptance and Commitment Therapy (1) · Aminolevulinic Acid (1) · Diet, Ketogenic (1) · Filgrastim (1) · Gemcitabine (1) · Granulocyte Colony-Stimulating Factor (1) · Irinotecan (1) · Methylphenidate (1) · RRx-001 (1) · Radiotherapy, Intensity-Modulated (1) · Re-Irradiation (1) · Surveys and Questionnaires (1) · Temozolomide (1) · fludarabine (1)
St. Jude Children's Research Hospital (3) · Aga Khan University (1) · Bambino Gesù Hospital and Research Institute (1) · Beijing Tiantan Hospital (1) · Capital Medical University (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dana-Farber Cancer Institute (1) · Danone Nutricia SpA Società Benefit (1) · EpicentRx, Inc. (1) · Hugo W. Moser Research Institute at Kennedy Krieger, Inc. (1) · Institut Claudius Regaud (1) · Nottingham University Hospitals NHS Trust (1) · Odense University Hospital (1) · Robbie Majzner (1) · Sheffield Children's NHS Foundation Trust (1)
United States (9) · Canada (2) · China (2) · Italy (2) · United Kingdom (2) · Denmark (1) · France (1) · Germany (1) · India (1) · Netherlands (1) · Pakistan (1)
Heather Conklin, PhD (2) · Bryan Oronsky, MD (1) · Derek Tsang, MD (1) · Fiona Schulte, PhD (1) · Giles W. Robinson, MD (1) · Howard Colman, MD PhD FAAN (1) · Maja V Maraldo (1) · Mathias Rathe, Consultant, MD, PhD (1) · Nicholas Whipple, MD, MPH (1) · Ola Rominyi, MBChB (1) · Rachel K Peterson, PhD (1) · Sabine Mueller, MD, PhD (1) · Samuel Cheshier, MD, PhD (1) · Sophie Thomas, DClinPsy (1) · Stephanie Fetzko, MD (1)
PMID 34078638, PMID 38363314, PMID 39626445
2014 (1), 2023 (1)