3 completed, 2 recruiting, 2 terminated, 2 withdrawn. 10 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 3, Recruiting 2, Terminated 2, Withdrawn 2, Unknown 1 |
| Phase 1 | 4 | Completed 2, Recruiting 1, Terminated 1 |
Follow Brain Neoplasm: new trials by email Literature Review of Brain Neoplasm trials Research Report on Brain Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ferumoxytol in Magnetic Resonance Imaging of Pediatric Patients With Brain Tumors Ferumoxytol, Magnetic Resonance Imaging - Brain Neoplasm | Phase 2 | Withdrawn | OHSU Knight Cancer Institute | 2017-10-20 | 2021-11-10 | |
| Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects DNX-2401, pembrolizumab - Brain Cancer, Brain Neoplasm | Phase 2 | Completed | DNAtrix, Inc. | 49 | 2016-10-06 | 2021-07-15 |
| Cetuximab-IRDye 800CW in Detecting Tumors in Patients With Malignant Glioma Undergoing Surgery Cetuximab, Cetuximab-IRDye 800CW, Tumor resection - Brain Neoplasm, Malignant Glioma | Phase 1 / Phase 2 | Terminated | Eben Rosenthal | 3 | 2016-10-01 | 2020-03-31 |
| Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma Intra-arterial Cetuximab, Intra-arterial Mannitol - Glioblastoma, Brain Cancer | Phase 1 / Phase 2 | Recruiting | Northwell Health | 33 | 2016-06-01 | 2026-06-01 |
| Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA Intra-arterial Cetuximab, Intra-arterial Mannitol, Hypofractionated re-irradiation - Glioblastoma, Anaplastic Astrocytoma | Phase 2 | Recruiting | Northwell Health | 37 | 2016-05-01 | 2026-04-13 |
| 18F-FET PET in Childhood Brain Tumours FET-PET - Brain Neoplasm | Phase 2 | Unknown | Charite University, Berlin, Germany | 160 | 2015-07-01 | 2017-07-21 |
| Bevacizumab With or Without Surgery for Adult Glioblastomas Craniotomy - Glioblastoma, Brain Neoplasm | Phase 2 | Withdrawn | National Institute of Neurological Disorders and Stroke (NINDS) | 2011-07-15 | 2017-07-02 | |
| Temozolomide as a Prophylaxis Against Brain Recurrence in Participants With Metastatic Breast Cancer (P05225 AM2) temozolomide - Breast Neoplasm, Brain Neoplasm | Phase 2 | Terminated | Merck Sharp & Dohme LLC | 6 | 2008-10-02 | 2017-06-14 |
| Safety and Tolerability Study of 131I-TM-601 to Treat Adult Patients With Recurrent Glioma. 131I-TM-601 - Glioma, Brain Neoplasm | Phase 1 / Phase 2 | Completed | TransMolecular | 18 | 2002-06-01 | 2009-03-31 |
| Clinical Study on 5-aminolevulinic Acid Hydrochloride (5-ALA) for Fluorescence-guided Resection of Malignant Gliomas Gliolan - Brain Neoplasm | Phase 1 / Phase 2 | Completed | medac GmbH | 21 | 2000-02-01 | 2016-05-23 |
Brain Neoplasms (10) · Glioblastoma (4) · Glioma (4) · Astrocytoma (1) · Breast Neoplasms (1) · Disease (1) · Gliosarcoma (1) · Neoplasms (1) · Neoplasms, Nerve Tissue (1) · Neoplasms, Neuroepithelial (1) · Neoplasms, Second Primary (1) · Nervous System Diseases (1) · Neuroectodermal Tumors (1)
Brain Diseases (10) · Central Nervous System Diseases (10) · Central Nervous System Neoplasms (10) · Neoplasms by Site (10) · Nervous System Neoplasms (10) · Neoplasms (9) · Nervous System Diseases (9) · Neoplasms by Histologic Type (6) · Neoplasms, Germ Cell and Embryonal (6) · Neoplasms, Glandular and Epithelial (6) · Neoplasms, Nerve Tissue (5) · Neoplasms, Neuroepithelial (5) · Neuroectodermal Tumors (5) · Astrocytoma (3) · Glioma (2)
Antibodies, Monoclonal (2) · Aminolevulinic Acid (1) · Cetuximab (1) · Chlorotoxin (1) · Craniotomy (1) · Ferrosoferric Oxide (1) · Magnetic Resonance Spectroscopy (1) · Oncolytic Virotherapy (1) · Temozolomide (1) · Transurethral Resection of Bladder (1) · pembrolizumab (1)
Northwell Health (2) · Charite University, Berlin, Germany (1) · DNAtrix, Inc. (1) · Eben Rosenthal (1) · Merck Sharp & Dohme LLC (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · OHSU Knight Cancer Institute (1) · TransMolecular (1) · medac GmbH (1)
United States (5) · Canada (1) · Germany (1)
Diana M Hablitz, MSNCRNP (1) · Eben Rosenthal, MD (1) · Edward A Neuwelt (1) · Gordon Li, MD (1) · John Boockvar, MD (1) · John K Park, M.D. (1) · Michail Plotkin, MD (1) · Nancy Gady, BS (1)
2008 (1), P30CA124435 (1)