5 completed, 2 terminated, 1 not yet recruiting, 1 recruiting. 10 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 5, Terminated 2, Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Phase 2 | 4 | Completed 2, Recruiting 1, Terminated 1 |
Follow Brain Neoplasm: new trials by email Literature Review of Brain Neoplasm trials Research Report on Brain Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of SRN-101 Administered Prior to Surgical Resection in Adults With Recurrent High-Grade Glioma. SRN-101, Blood Specimen Collection, Surgical Resection - Recurrent High-Grade Gliomas, Brain Neoplasm | Phase 1 | Not yet recruiting | Nicholas Butowski | 6 | 2026-11-15 | 2026-10-27 |
| Fractionated Stereotactic Radiosurgery With Concurrent Bevacizumab for Brain Metastases: A Phase I Dose-escalation Trial Fractionated stereotactic radiosurgery, bevacizumab - Brain Neoplasm | Phase 1 | Unknown | National Taiwan University Hospital | 36 | 2018-01-01 | 2017-08-18 |
| Cetuximab-IRDye 800CW in Detecting Tumors in Patients With Malignant Glioma Undergoing Surgery Cetuximab, Cetuximab-IRDye 800CW, Tumor resection - Brain Neoplasm, Malignant Glioma | Phase 1 / Phase 2 | Terminated | Eben Rosenthal | 3 | 2016-10-01 | 2020-03-31 |
| Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma Intra-arterial Cetuximab, Intra-arterial Mannitol - Glioblastoma, Brain Cancer | Phase 1 / Phase 2 | Recruiting | Northwell Health | 33 | 2016-06-01 | 2026-06-01 |
| An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma IL13-PE38QQR - Brain Neoplasm, Glioma | Phase 1 | Terminated | National Institute of Neurological Disorders and Stroke (NINDS) | 7 | 2009-04-07 | 2018-07-05 |
| Monteris AutoLITT™ FIM Safety Trial for Recurrent/Progressive Brain Tumors AutoLITT system - Brain Tumor, Brain Tumor, Recurrent | Phase 1 | Completed | Monteris Medical | 10 | 2008-08-01 | 2021-08-24 |
| Safety and Tolerability Study of 131I-TM-601 to Treat Adult Patients With Recurrent Glioma. 131I-TM-601 - Glioma, Brain Neoplasm | Phase 1 / Phase 2 | Completed | TransMolecular | 18 | 2002-06-01 | 2009-03-31 |
| Clinical Study on 5-aminolevulinic Acid Hydrochloride (5-ALA) for Fluorescence-guided Resection of Malignant Gliomas Gliolan - Brain Neoplasm | Phase 1 / Phase 2 | Completed | medac GmbH | 21 | 2000-02-01 | 2016-05-23 |
| Gene Therapy for the Treatment of Brain Tumors Cytovene (Ganciclovir Sodium), G1TKSVNa.53 Producer Cell Line - Brain Neoplasm, Neoplasm Metastasis | Phase 1 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 15 | 1992-08-21 | 2017-07-02 |
| A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas Motexafin Gadolinium Injection - Glioma, Glioblastoma | Phase 1 | Completed | Pharmacyclics LLC. | 24 | 2009-04-03 |
Brain Neoplasms (10) · Glioma (5) · Glioblastoma (3) · Astrocytoma (1) · Multiple Acyl Coenzyme A Dehydrogenase Deficiency (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Oligodendroglioma (1)
Brain Diseases (10) · Central Nervous System Diseases (10) · Central Nervous System Neoplasms (10) · Neoplasms by Site (10) · Nervous System Diseases (10) · Nervous System Neoplasms (10) · Neoplasms (9) · Neoplasms by Histologic Type (7) · Neoplasms, Germ Cell and Embryonal (7) · Neoplasms, Glandular and Epithelial (7) · Neoplasms, Nerve Tissue (7) · Neoplasms, Neuroepithelial (7) · Neuroectodermal Tumors (7) · Astrocytoma (2) · Glioma (2)
Aminolevulinic Acid (1) · Antibodies, Monoclonal (1) · Bevacizumab (1) · Blood Specimen Collection (1) · Cetuximab (1) · Chlorotoxin (1) · Ganciclovir (1) · IL13-PE38 (1) · Magnetic Resonance Spectroscopy (1) · Transurethral Resection of Bladder (1) · motexafin gadolinium (1)
National Institute of Neurological Disorders and Stroke (NINDS) (2) · Eben Rosenthal (1) · Monteris Medical (1) · National Taiwan University Hospital (1) · Nicholas Butowski (1) · Northwell Health (1) · Pharmacyclics LLC. (1) · TransMolecular (1) · medac GmbH (1)
United States (8) · Taiwan (1)
Andrew Sloan, MD (1) · Chia-Chun Wang (1) · Diana M Hablitz, MSNCRNP (1) · Eben Rosenthal, MD (1) · Gene Barnett, MD (1) · Gordon Li, MD (1) · John D Heiss, M.D. (1) · Nicholas Butowski, MD (1)
PMID 23560574, PMID 24410126, PMID 24792486
P30CA124435 (1)