4 completed, 3 active not recruiting, 3 not yet recruiting, 3 recruiting. 12 Not applicable, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 4, Not yet recruiting 3, Recruiting 3, Active not recruiting 2 |
| Early Phase 1 | 1 | Active not recruiting 1 |
Follow Asymptomatic Apical Periodontitis: new trials by email Literature Review of Asymptomatic Apical Periodontitis trials Research Report on Asymptomatic Apical Periodontitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Intracanal Cryotherapy on Biomarkers and Postoperative Pain in Apical Periodontitis Temperature-Controlled Intracanal Irrigation - Asymptomatic Apical Periodontitis | Not applicable | Not yet recruiting | Medipol University | 120 | 2026-10-01 | 2026-09-30 |
| Sonic Irrigation Activation for Postoperative Pain After Root Canal Treatment Sonic Irrigation Activation Using EndoActivator, Conventional Syringe Irrigation - Asymptomatic Apical Periodontitis | Not applicable | Not yet recruiting | Saidu College of Dentistry | 176 | 2026-09-25 | 2026-09-29 |
| Cryotherapy, PGE2, NGF Levels and Pain After Endodontic Retreatment Intracanal cryotherapy, Room-temperature saline irrigation - Asymptomatic Apical Periodontitis, Endodontic Retreatment | Not applicable | Not yet recruiting | Alanya Alaaddin Keykubat University | 100 | 2026-08-01 | 2026-07-29 |
| Postoperative Pain and Quality of Life Following Root Canal Treatment With Two Different Sealers AH Plus, BioRoot Flow - Asymptomatic Apical Periodontitis | Not applicable | Completed | Karadeniz Technical University | 58 | 2026-04-01 | 2026-10-21 |
| Effect of Calcium-Based Bioceramic Sealer and Resin-Based Sealer on Postoperative Pain Resin-based sealer obturation technique, Bioceramic sealer obturation - Asymptomatic Apical Periodontitis | Not applicable | Recruiting | Fatima Memorial Hospital | 60 | 2025-12-01 | 2025-12-24 |
| Effect of Rotary File Number on MB2 Canal Negotiation and Postoperative Pain One Curve Rotary File, Perfect Super System Minimal Invasive Kit, VDW Rotate - Postoperative Pain, Asymptomatic Apical Periodontitis | Not applicable | Completed | Mehmet Adıgüzel | 168 | 2025-07-29 | 2026-09-09 |
| Non-Surgical Single Visit Endodontic Retreatment in Cases With Asymptomatic Apical Periodontitis Using Bioceramic Sealer Bioceramic sealer root canal obturation, resin sealer root canal obturation - Asymptomatic Apical Periodontitis, Root Canal Retreatment | Not applicable | Active not recruiting | Saly Nazeer | 70 | 2025-06-01 | 2026-08-06 |
| Evaluation of Postoperative Pain After Using Resin-Based and Bioceramic Sealers in Mandibular Molars With Asymptomatic Apical Periodontitis BioRoot RCS, AH Plus - Asymptomatic Apical Periodontitis | Not applicable | Completed | AZİZ ŞAHİN ERDOĞAN | 70 | 2025-03-12 | 2025-12-17 |
| Comparison of the Effects of Bio Ceramic and Epoxy Resin-based Sealers on Postoperative Pain After Root Canal Treatment AH plus sealer, Bioceramic sealer - Asymptomatic Apical Periodontitis | Not applicable | Recruiting | Primary Health Care Corporation, Qatar | 40 | 2024-10-28 | 2024-11-25 |
| Evaluation of Postoperative Pain and Success Rate Between Lateral Condensation and Warm Vertical Obturation Techniques Warm Vertical Condensation (WVO), Cold Lateral Condensation (CLC) - Necrotic Pulp, Asymptomatic Apical Periodontitis | Not applicable | Recruiting | University of Jordan | 80 | 2024-10-17 | 2026-04-02 |
| Antimicrobial Effect of Calcium Silicate and Pectin as Intracanal Medications in Necrotic Teeth With Periapical Lesions Calcium Hydroxide Intracanal medication, Calcium silicate based intracanal medication, Pectin - Asymptomatic Apical Periodontitis | Early Phase 1 | Active not recruiting | Suez Canal University | 63 | 2024-09-01 | 2026-02-20 |
| Effects of Irrigation Activation Systems on Postoperative Pain and Lesion Healing in Single-Visit Retreatment Ultrasonic Activation Group, Sonic Activation Group, Laser Activation Group - Retreatment, Asymptomatic Apical Periodontitis | Not applicable | Active not recruiting | Ege University | 75 | 2024-08-01 | 2026-09-14 |
| Effect of EDDY Sonic Irrigation on Root Canal Microbiota and Pain in Asymptomatic Apical Periodontitis EDDY Sonic Activation, Conventional Syringe Irrigation - Asymptomatic Apical Periodontitis, Root Canal Infection | Not applicable | Completed | Abdulkadir Tiftik,DDS | 40 | 2021-11-20 | 2026-02-20 |
Pain, Postoperative (7) · Dental Pulp Necrosis (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Periapical Diseases (1) · Periapical Periodontitis (1) · Toothache (1)
Pathologic Processes (8) · Pathological Conditions, Signs and Symptoms (8) · Neurologic Manifestations (7) · Pain (7) · Postoperative Complications (7) · Signs and Symptoms (7) · Stomatognathic Diseases (2) · Tooth Diseases (2) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Dental Pulp Diseases (1) · Facial Pain (1) · Genetic Diseases, Inborn (1) · Heredodegenerative Disorders, Nervous System (1) · Jaw Diseases (1)
epoxy resin-based root canal sealer (2) · Pectins (1)
AZİZ ŞAHİN ERDOĞAN (1) · Abdulkadir Tiftik,DDS (1) · Alanya Alaaddin Keykubat University (1) · Ege University (1) · Fatima Memorial Hospital (1) · Karadeniz Technical University (1) · Medipol University (1) · Mehmet Adıgüzel (1) · Primary Health Care Corporation, Qatar (1) · Saidu College of Dentistry (1) · Saly Nazeer (1) · Suez Canal University (1) · University of Jordan (1)
Turkey (Türkiye) (7) · Egypt (2) · Jordan (1) · Pakistan (1) · Qatar (1)
Abdulkadir Tiftik, DDS, DDS (1) · Dareen Azzouz (1) · Nehal Lehita, Phd (1) · Omar Montaser, M.D.Sc (1) · Sybel M Moussa, Phd (1)