7 recruiting, 5 completed, 1 active not recruiting, 1 terminated. 4 Phase 1, 4 Phase 2, 2 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Active not recruiting 1, Completed 1, Recruiting 1, Terminated 1 |
| Phase 2 | 4 | Completed 3, Active not recruiting 1 |
| Not applicable | 2 | Recruiting 2 |
| Phase 4 | 1 | Recruiting 1 |
Follow Appendiceal Cancer: new trials by email Literature Review of Appendiceal Cancer trials Research Report on Appendiceal Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Molecular Profiling for Risk Stratification in Appendiceal Cancer DNA Methylation Profiling, m6A Epitranscriptomic Profiling - Appendiceal Cancer, Appendiceal Adenocarcinoma | Recruiting | City of Hope Medical Center | 400 | 2026-05-01 | 2026-06-29 | |
| A Feasibility Study of Mass-Based Response Drug Screening to Guide Personalized Hyperthermic Intraperitoneal Chemotherapy for High-Grade Appendiceal and Colorectal Adenocarcinoma With Peritoneal Metastasis Mass-based response testing (MRT) - Appendiceal Cancer, Colorectal Adenocarcinoma | Not applicable | Recruiting | Yale University | 20 | 2026-02-17 | 2026-07-21 |
| Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™) CYTALUX™ (pafolacianine) - Gastrointestinal Cancer, Gastric Cancer | Phase 4 | Recruiting | Cedars-Sinai Medical Center | 15 | 2025-09-05 | 2025-09-15 |
| Molecular Characterisation of Appendiceal Cancer Retrospective tissue sample analysis - Appendiceal Cancer | Recruiting | The Christie NHS Foundation Trust | 100 | 2024-02-04 | 2025-01-01 | |
| Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG) Ablative local therapy - Small Bowel Cancer, Colorectal Cancer | Not applicable | Recruiting | University of California, Davis | 300 | 2023-10-05 | 2026-07-02 |
| Genetics of Appendix Cancer Study Genetic profiling, Retrospective tissue procurement - Appendix Cancer, Appendiceal Cancer | Recruiting | Andreana Holowatyj, PhD, MSCI | 700 | 2022-11-11 | 2025-04-18 | |
| Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis Paclitaxel, Nilotinib, ECG - Gynecologic Cancer, Gynecologic Neoplasms | Phase 2 | Completed | National Cancer Institute (NCI) | 21 | 2022-10-13 | 2026-06-25 |
| JAB-21822 in Combination With Cetuximab in Patients With Advanced CRC and Other Solid Tumors With KRAS G12C Mutation JAB-21822, Cetuximab - Advanced Colorectal Cancer, Small Intestinal Cancer | Phase 1 / Phase 2 | Active not recruiting | Allist Pharmaceuticals, Inc. | 48 | 2022-02-17 | 2026-03-16 |
| Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies Sodium Thiosulfate, 5-Fluorouracil, Oxaliplatin - Peritoneal Mesothelioma, Peritoneal Carcinomatosis | Phase 1 | Recruiting | National Cancer Institute (NCI) | 60 | 2021-10-19 | 2026-10-16 |
| Intraperitoneal Oxaliplatin in Combo w IV mFOLFIRI for Peritoneal Carcinomatosis From Colorectal & Appendiceal Cancer Oxaliplatin, mFOLFIRI - Colorectal Cancer, Appendiceal Cancer | Phase 1 | Terminated | University of Utah | 1 | 2021-03-22 | 2021-09-27 |
| Trial of Cytoreductive Surgery and HIPEC in Patients With Primary and Secondary Peritoneal Cancers HIPEC, Mitomycin c, CDDP 50 - Stomach Cancer, Colorectal Cancer | Completed | Holy Name Medical Center, Inc. | 10 | 2018-05-15 | 2022-08-03 | |
| A Study to Investigate ONCOS-102 in Combination With Durvalumab in Subjects With Advanced Peritoneal Malignancies ONCOS-102, Durvalumab, Cyclophosphamide - Colorectal Cancer, Ovarian Cancer | Phase 1 / Phase 2 | Completed | Ludwig Institute for Cancer Research | 67 | 2017-09-07 | 2022-12-22 |
| HIPEC for Peritoneal Carcinomatosis HIPEC, Mitomycin C - Peritoneal Carcinomatosis, Colorectal Cancer | Phase 2 | Completed | Albert Einstein College of Medicine | 51 | 2011-11-01 | 2024-10-24 |
| Surgical Outcome and Predictors of Overall Survival of Stage I-III Appendiceal Adenocarcinoma Partial colecctomy, Hemicolectomy - Appendiceal Cancer | Completed | Mansoura University | 2607 | 2005-01-01 | 2022-07-11 |
Appendiceal Neoplasms (14) · Colorectal Neoplasms (7) · Ovarian Neoplasms (4) · Peritoneal Neoplasms (3) · Stomach Neoplasms (3) · Adenocarcinoma, Mucinous (2) · Cholangiocarcinoma (2) · Gastrointestinal Neoplasms (2) · Biliary Tract Neoplasms (1) · Breast Neoplasms (1) · Esophageal Neoplasms (1) · Fallopian Tube Neoplasms (1) · Gallbladder Neoplasms (1) · Genital Neoplasms, Female (1) · Necrosis (1)
Cecal Diseases (14) · Cecal Neoplasms (14) · Digestive System Diseases (14) · Digestive System Neoplasms (14) · Gastrointestinal Diseases (14) · Intestinal Diseases (14) · Intestinal Neoplasms (14) · Neoplasms (14) · Neoplasms by Site (14) · Gastrointestinal Neoplasms (12) · Colonic Diseases (7) · Rectal Diseases (7) · Adenocarcinoma (5) · Carcinoma (5) · Neoplasms by Histologic Type (5)
Mitomycin (3) · Cisplatin (2) · Doxorubicin (2) · Hyperthermic Intraperitoneal Chemotherapy (2) · Oxaliplatin (2) · Cetuximab (1) · Colectomy (1) · Cyclophosphamide (1) · DNA Fingerprinting (1) · Electrocardiography (1) · Fluorouracil (1) · Laparoscopy (1) · Paclitaxel (1) · Pafolacianine (1) · durvalumab (1)
National Cancer Institute (NCI) (2) · Albert Einstein College of Medicine (1) · Allist Pharmaceuticals, Inc. (1) · Andreana Holowatyj, PhD, MSCI (1) · Cedars-Sinai Medical Center (1) · City of Hope Medical Center (1) · Holy Name Medical Center, Inc. (1) · Ludwig Institute for Cancer Research (1) · Mansoura University (1) · The Christie NHS Foundation Trust (1) · University of California, Davis (1) · University of Utah (1) · Yale University (1)
United States (12) · China (1) · United Kingdom (1)
Andrew M Blakely, M.D. (2) · Andreana N Holowatyj, PhD, MSCI (1) · Edward Kim, MD, PhD (1) · John McAuliffe, M.D. (1) · Kiran Turaga, MD (1) · Laura Lambert, MD (1) · Miguel Burch, MD (1)
P30CA093373 (1)