7 recruiting. 7 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Recruiting 7 |
| Phase 1 | 1 | Recruiting 1 |
Follow Aplastic Anemia: new trials by email Literature Review of Aplastic Anemia trials Research Report on Aplastic Anemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase I/II Study of Anti-CD38 Monoclonal Antibody in Refractory Severe Aplastic Anemia Isatuximab - Aplastic Anemia | Phase 1 / Phase 2 | Recruiting | Institute of Hematology & Blood Diseases Hospital, China | 32 | 2026-06-30 | 2026-09-21 |
| Indication of HSCT in Patients With Refractory/Relapse AA After First-line Standard Immunosuppressive Therapy Aged More Than 40 Years Allogeneic hematopoietic stem cell transplantation Stem cell source only Bone Marrow - Aplastic Anemia | Phase 2 | Recruiting | Assistance Publique - Hôpitaux de Paris | 52 | 2025-01-24 | 2026-04-28 |
| A Study of Emapalumab for Pediatric Aplastic Anemia Emapalumab - Aplastic Anemia, Cytopenia | Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 35 | 2024-05-21 | 2025-12-17 |
| Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors Nicotinamide Riboside, Placebo, Exercise Intervention - Lymphoblastic Leukemia, Cancer Survivors | Phase 2 | Recruiting | Children's Hospital of Philadelphia | 80 | 2023-02-23 | 2025-12-04 |
| Two Step Haplo With Radiation Conditioning Fludarabine, Total-Body Irradiation, Donor Lymphocyte Infusion - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 2 | Recruiting | Thomas Jefferson University | 63 | 2021-10-25 | 2025-10-30 |
| Haploidentical HCT for Severe Aplastic Anemia Anti-Thymocyte Globulin (Rabbit), Fludarabine, Cyclophosphamide - Aplastic Anemia, Bone Marrow Failure Syndrome | Phase 2 | Recruiting | St. Jude Children's Research Hospital | 21 | 2021-01-21 | 2026-09-16 |
| Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic Syndrome Anti-Thymocyte Globulin, Cyclosporine, Filgrastim - Aplastic Anemia, de Novo Myelodysplastic Syndrome | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 140 | 2012-06-25 | 2026-06-22 |
Anemia, Aplastic (7) · Myelodysplastic Syndromes (3) · Bone Marrow Failure Disorders (2) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (2) · Cytopenia (1) · Hodgkin Disease (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Leukemia, Myeloid (1) · Leukemia, Myeloid, Acute (1) · Leukemia, Myelomonocytic, Chronic (1) · Lymphoma, Non-Hodgkin (1) · Multiple Myeloma (1) · Polycythemia Vera (1) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (1)
Anemia (7) · Bone Marrow Diseases (7) · Hematologic Diseases (7) · Hemic and Lymphatic Diseases (7) · Bone Marrow Failure Disorders (5) · Immune System Diseases (2) · Immunoproliferative Disorders (2) · Leukemia (2) · Leukemia, Lymphoid (2) · Lymphatic Diseases (2) · Lymphoproliferative Disorders (2) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Pathological Conditions, Signs and Symptoms (2) · Atrophy (1)
Antilymphocyte Serum (2) · Cyclophosphamide (2) · Filgrastim (2) · Granulocyte Colony-Stimulating Factor (2) · fludarabine (2) · thymoglobulin (2) · Biopsy (1) · Cyclosporine (1) · Cyclosporins (1) · Emapalumab (1) · Hematopoietic Stem Cell Transplantation (1) · Medrol Veriderm (1) · Melphalan (1) · Mesna (1) · Methylprednisolone (1)
Assistance Publique - Hôpitaux de Paris (1) · Children's Hospital of Philadelphia (1) · Institute of Hematology & Blood Diseases Hospital, China (1) · M.D. Anderson Cancer Center (1) · Memorial Sloan Kettering Cancer Center (1) · St. Jude Children's Research Hospital (1) · Thomas Jefferson University (1)
United States (5) · China (1) · France (1)
Akshay Sharma, MBBS (1) · Amr Qudeimat, MD (1) · Andromachi Scaradavou, MD (1) · Jun Shi, PhD (1) · Sogol Mostoufi-Moab, MD, MSCE (1) · Tapan M Kadia (1) · Usama Gergis, MD (1)
R01CA254955 (1)