Aplastic Anemia: Clinical Trials

25 trials for Aplastic Anemia, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

12 completed, 6 unknown, 3 terminated, 2 recruiting. 25 Phase 1, 16 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 125Completed 12, Unknown 6, Terminated 3, Recruiting 2, Active not recruiting 1, Not yet recruiting 1
Phase 216Completed 7, Unknown 4, Recruiting 2, Active not recruiting 1, Not yet recruiting 1, Terminated 1

Follow Aplastic Anemia: new trials by email Literature Review of Aplastic Anemia trials Research Report on Aplastic Anemia

Trials (filtered) newest first · largest first

All 25 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Phase I/II Study of Anti-CD38 Monoclonal Antibody in Refractory Severe Aplastic Anemia
Isatuximab - Aplastic Anemia
Phase 1 / Phase 2RecruitingInstitute of Hematology & Blood Diseases Hospital, China322026-06-302026-09-21
The Safety and Efficacy of Daratumumab in Patients With Refractory Aplastic Anemia
Daratumumab - Aplastic Anemia, Refractory
Phase 1 / Phase 2RecruitingInstitute of Hematology & Blood Diseases Hospital, China372025-12-172026-11-06
Study of CM313(SC) Injection in Subjects With Relapsed/Refractory Aplastic Anemia
CM313(SC) injection - Aplastic Anemia
Phase 1 / Phase 2Not yet recruitingKeymed Biosciences Co.Ltd1252025-03-012025-02-18
Efficacy of Daratumumab to Overcome Platelet Transfusion Refractoriness in Patients with Aplastic Anemia
Daratumumab - Aplastic Anemia, Platelet Transfusion Refractoriness
Phase 1CompletedInstitute of Hematology & Blood Diseases Hospital, China102023-04-172025-01-03
Autologous Tregs for Aplastic Anaemia
Expanded autologous T regulatory cells - Aplastic Anemia
Phase 1UnknownKing's College Hospital NHS Trust122022-07-142023-10-05
Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization
Best Practice, Ibrutinib - Aplastic Anemia, Hematopoietic and Lymphoid Cell Neoplasm
Phase 1CompletedJennifer Woyach102020-10-232023-12-26
Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant
Anti-Thymocyte Globulin, Cyclophosphamide, Cytokine-treated Veto Cells - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Phase 1 / Phase 2Active not recruitingM.D. Anderson Cancer Center162019-08-082026-06-11
Engineered Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies
Cyclophosphamide, Filgrastim, Fludarabine Phosphate - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Phase 1CompletedM.D. Anderson Cancer Center112017-01-182023-02-16
Umbilical Cord Derived Mesenchymal Stem Cells Therapy in Aplastic Anemia
mesenchymal stem cells - Aplastic Anemia
Phase 1UnknownHebei Medical University102017-01-012017-04-07
Nandrolone Decanoate in the Treatment of Telomeropathies
Nandrolone Decanoate - Aplastic Anemia, Bone Marrow Failure Syndromes
Phase 1 / Phase 2CompletedUniversity of Sao Paulo202014-02-012023-08-31
Open-label Clinical Trial to Investigate the Safety and Tolerability of Allogeneic B-cell Concentrates for Immune Reconstitution After Allogeneic Stem Cell Transplantation Measured as Response to a Antedated Single Vaccination
allogeneic donor derived B-lymphocytes - Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia
Phase 1 / Phase 2UnknownUniversity of Erlangen-Nürnberg Medical School152013-11-012014-03-26
Danazol for Genetic Bone Marrow and Lung Disorders
Danazol - Aplastic Anemia
Phase 1 / Phase 2CompletedNational Heart, Lung, and Blood Institute (NHLBI)272011-07-192018-08-15
Alefacept in Patients With Relapsed/Refractory Aplastic Anemia
Alefacept - Aplastic Anemia
Phase 1TerminatedThe Cleveland Clinic42011-05-012018-01-26
Mesenchymal Stem Cells in the Treatment of Relapsed/Refractory Severe Acquired Aplastic Anemia
Intravenous bone marrow mesenchymal stem cells infusion - Aplastic Anemia
Phase 1 / Phase 2CompletedUniversity of Sao Paulo92011-02-012014-02-04
Mesenchymal Stem Cells Transplantation to Patients With Relapsed/Refractory Aplastic Anemia.
bone marrow derived mesenchymal stem cells - Aplastic Anemia
Phase 1 / Phase 2UnknownGuangzhou General Hospital of Guangzhou Military Command502011-02-012011-03-01
Cyclophosphamide Plus Cyclosporine in Treatment-Naive Severe Aplastic Anemia
Cyclophosphamide, Cyclosporine - Aplastic Anemia, Neutropenia
Phase 1 / Phase 2CompletedNational Heart, Lung, and Blood Institute (NHLBI)222010-08-012017-05-22
A Pilot Study of Fludarabine Plus Cyclophosphamide in Refractory Severe Aplastic Anemia
Cyclophosphamide, Fludarabine - Aplastic Anemia, Neutropenia
Phase 1 / Phase 2CompletedNational Heart, Lung, and Blood Institute (NHLBI)12010-08-012021-07-02
Human Leukocyte Antigen (HLA)-Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Aplastic Anemia
anti-thymocyte globulin, filgrastim, Fludarabine - Aplastic Anemia
Phase 1 / Phase 2CompletedAsan Medical Center122009-07-012013-01-03
Study of Fludarabine + Cyclophosphamide + TBI Conditioning Regimen for Double Units Cord Blood Transplantation(CBT)in Severe Aplastic Anemia(SAA)
Cyclophosphosphamide, TBI - Aplastic Anemia
Phase 1 / Phase 2UnknownThe Korean Society of Pediatric Hematology Oncology52008-11-012012-03-26
Treatment of Menorrhagia in Women With Thrombocytopenia Using Platelets or Platelets and Hormones
Lo-Ovral Oral Contraceptive Pills, Placebo - sugar pill - Aplastic Anemia, Menorrhagia
Phase 1 / Phase 2TerminatedEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)12007-11-012013-07-19

Showing 20 of 25. Sign in to see all of them.

Narrower conditions

Anemia, Aplastic (25)  ·  Myelodysplastic Syndromes (5)  ·  Bone Marrow Failure Disorders (3)  ·  Hodgkin Disease (3)  ·  Leukemia, Myeloid, Acute (3)  ·  Lymphoma, Non-Hodgkin (3)  ·  Multiple Myeloma (3)  ·  Pancytopenia (3)  ·  Precursor Cell Lymphoblastic Leukemia-Lymphoma (3)  ·  Hematologic Neoplasms (2)  ·  Leukemia, Lymphocytic, Chronic, B-Cell (2)  ·  Leukemia, Myelogenous, Chronic, BCR-ABL Positive (2)  ·  Myeloproliferative Disorders (2)  ·  Neutropenia (2)  ·  Amenorrhea (1)

Broader conditions

Anemia (25)  ·  Bone Marrow Diseases (25)  ·  Hematologic Diseases (25)  ·  Hemic and Lymphatic Diseases (25)  ·  Bone Marrow Failure Disorders (22)  ·  Pathologic Processes (6)  ·  Pathological Conditions, Signs and Symptoms (6)  ·  Immune System Diseases (5)  ·  Neoplasms (5)  ·  Blood Protein Disorders (4)  ·  Cytopenia (4)  ·  Disease Attributes (4)  ·  Immunoproliferative Disorders (4)  ·  Paraproteinemias (4)  ·  Cardiovascular Diseases (3)

Interventions

Cyclophosphamide (6)  ·  Whole-Body Irradiation (4)  ·  Antilymphocyte Serum (3)  ·  Filgrastim (3)  ·  Granulocyte Colony-Stimulating Factor (3)  ·  fludarabine (3)  ·  Cyclosporine (2)  ·  Cyclosporins (2)  ·  Peripheral Blood Stem Cell Transplantation (2)  ·  daratumumab (2)  ·  Alefacept (1)  ·  Blood Component Removal (1)  ·  CT-P10 (1)  ·  Cord Blood Stem Cell Transplantation (1)  ·  Danazol (1)

Sponsors

National Heart, Lung, and Blood Institute (NHLBI) (5)  ·  Institute of Hematology & Blood Diseases Hospital, China (3)  ·  M.D. Anderson Cancer Center (2)  ·  University of Sao Paulo (2)  ·  Asan Medical Center (1)  ·  Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1)  ·  Fred Hutchinson Cancer Center (1)  ·  Guangzhou General Hospital of Guangzhou Military Command (1)  ·  Hebei Medical University (1)  ·  Jennifer Woyach (1)  ·  Joanne Kurtzberg, MD (1)  ·  Keymed Biosciences Co.Ltd (1)  ·  King's College Hospital NHS Trust (1)  ·  The Cleveland Clinic (1)  ·  The Korean Society of Pediatric Hematology Oncology (1)

Countries

United States (12)  ·  China (6)  ·  Brazil (2)  ·  Germany (2)  ·  South Korea (2)  ·  Austria (1)  ·  United Kingdom (1)

Top investigators

Danielle M Townsley, M.D. (2)  ·  Ana Beatriz Hortense, MD (1)  ·  Ann Woolfrey (1)  ·  Baoyong Yan, Doctor (1)  ·  Bing Ma, Master (1)  ·  Bojian Sun, Master (1)  ·  Dan Zhao, Master (1)  ·  Fan Zhang, Bachelor (1)  ·  Ghulam Mufti (1)  ·  Ho Joon Im, MD & PhD (1)  ·  Hyo Seop Ahn, M.D, Ph.D (1)  ·  Jennifer A Woyach, MD (1)  ·  Joanne Kurtzberg, MD (1)

Results publications

PMID 22055111, PMID 23731760, PMID 25185712, PMID 25310303, PMID 26589752, PMID 27192671, PMID 34724566, PMID 36579443, PMID 38467031, PMID 40331918, PMID 41742894