339 completed, 75 terminated, 68 recruiting, 37 unknown. 600 Phase 1, 233 Phase 2.
Follow Anemia: new trials by email Literature Review of Anemia trials Research Report on Anemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prenatal Transplantation for Fetuses With Fanconi Anemia IUHSCT for FA-affected fetuses - Fanconi Anemia, Anemia, Hypoplastic, Congenital | Phase 1 / Phase 2 | Not yet recruiting | Agnieszka Czechowicz | 12 | 2028-01-01 | 2026-06-16 |
| A Phase 1b/2a Study of Velinotamig in Adults With Relapsed/Refractory ITP and wAIHA Velinotamig specified dose on specified days. - Immune Thrombocytopenia (ITP), Warm Autoimmune Hemolytic Anemia (WAIHA) | Phase 1 / Phase 2 | Not yet recruiting | Cullinan Therapeutics Inc. | 72 | 2026-12-01 | 2026-07-31 |
| Minocycline In Neurocognitive Outcomes - Sickle Cell Disease Minocycline, Placebo - Sickle Cell Disease, Cognitive Impairment | Phase 1 | Not yet recruiting | University of Cincinnati | 30 | 2026-12-01 | 2026-05-14 |
| Research on YTS109 Cell in Patients With Recurrent/Refractory Autoimmune Hemolytic Anemia YTS109 cell - Autoimmune Hemolytic Anemia | Phase 1 | Not yet recruiting | China Immunotech (Beijing) Biotechnology Co., Ltd. | 13 | 2026-11-18 | 2026-10-22 |
| Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms pacritinib - Myelodysplastic Syndromes | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 160 | 2026-11-04 | 2026-10-30 |
| Feasibility and Acceptability of Amani Amani - Sickle Cell Disease | Phase 1 / Phase 2 | Not yet recruiting | Massachusetts General Hospital | 40 | 2026-11-01 | 2026-08-07 |
| Study of CTX001 in Adults With Anemia Due to Non-Dialysis-Dependent Chronic Kidney Disease Placebo, CTX001, Ferrous Sulfate - Chronic Kidney Disease, Anemia | Phase 1 | Not yet recruiting | Cajal Therapeutics Inc. | 24 | 2026-11-01 | 2026-10-28 |
| Safety and Tolerability of Metformin and Naproxen for Cancer Prevention in Fanconi Anemia Metformin, Naproxen Sodium - Fanconi Anemia, Head and Neck Cancer | Phase 1 | Recruiting | Rockefeller University | 80 | 2026-10-14 | 2026-10-28 |
| Phase 1 Study of F182112 in Relapsed/Refractory Autoimmune Hemolytic Anemia F182112 single-agent - Autoimmune Hemolytic Anemia | Phase 1 | Not yet recruiting | Institute of Hematology & Blood Diseases Hospital, China | 12 | 2026-10-10 | 2026-09-11 |
| Buprenorphine for the Management of Pain in Children With Sickle Cell Disease Buprenorphine Buccal Film [Belbuca] - Sickle Cell Disease (SCD), Sickle Cell Disease Vaso-occlusive Crisis | Phase 1 | Not yet recruiting | Natasha Archer | 25 | 2026-10-01 | 2026-09-02 |
| Sirolimus+Ruxolitinib+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to CNI Sirolimus, Ruxolitinib, MMF - Acute Leukemia, Myelodysplastic Syndromes | Phase 1 / Phase 2 | Not yet recruiting | Peking University People's Hospital | 40 | 2026-10-01 | 2026-09-09 |
| To Evaluate Safety, Tolerability, PK/PD & Food Effect of Single/Multiple Oral TUL321 Capsules in Healthy Participants. Part1: TUL321, Part1: Placebo, Part2: TUL321 - Paroxysmal Nocturnal Hemoglobinuria, PNH | Phase 1 | Recruiting | Zhuhai United Laboratories Co., Ltd. | 94 | 2026-08-26 | 2026-09-01 |
| A Phase 1/2 Study to Evaluate the Safety and Efficacy of Dibotatug (DR-01) in Adults With Bone Marrow Failure Syndromes Dibotatug (DR-01) - Bone Marrow Failure Syndromes, Aplastic Anemias | Phase 1 / Phase 2 | Not yet recruiting | Dren Bio | 60 | 2026-08-01 | 2026-07-24 |
| Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Sickle Cell Disease autologous bone marrow derived CD34+ HSPCs electroporated with BCL11A enhancer targeting Cas9 ribonucleoprotein, Sequencing Assay for Variant rs114518452 - Sickle Cell Disease, Sickle Cell Anemia (HbSS, or HbSβ-thalassemia0) | Phase 1 | Recruiting | Daniel Bauer | 5 | 2026-08-01 | 2026-10-21 |
| Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell Disease VAS-101 - Sickle Cell Disease, Hemolytic Anemia | Phase 1 | Recruiting | National Heart, Lung, and Blood Institute (NHLBI) | 25 | 2026-07-31 | 2026-10-21 |
| A Study of Ferric Derisomaltose Injection in Chinese Participants With Iron Deficiency Anemia Under Fasting Conditions Ferric Derisomaltose Injection, Ferric Derisomaltose Injection [MonoFer®] - Iron Deficiency Anemia | Phase 1 | Recruiting | Sichuan Huiyu Pharmaceutical Co., Ltd | 88 | 2026-07-23 | 2026-10-13 |
| High-Dose Vitamin C in G6PDA and Pyruvate Kinase Deficiency: A Safety Study Vitamin C - Pyruvate Kinase Deficiency, Glucose 6 Phosphate Dehydrogenase Deficiency | Phase 1 | Not yet recruiting | University of Utah | 3 | 2026-07-15 | 2026-05-28 |
| Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors Total Body Irradiation, Alemtuzumab, Abatacept - Sickle Cell Disease, Beta-thalassemia | Phase 1 / Phase 2 | Recruiting | National Heart, Lung, and Blood Institute (NHLBI) | 90 | 2026-07-08 | 2026-10-13 |
| HY001N for Patients With Autoimmune Hemolytic Anemia After Failure ≥3 Lines of Therapy. HY001N Cell Injection - Autoimmune Hemolytic Anemia (AIHA) | Phase 1 | Recruiting | Juventas Cell Therapy Ltd. | 9 | 2026-07-02 | 2026-08-05 |
| Phase I/II Study of Anti-CD38 Monoclonal Antibody in Refractory Severe Aplastic Anemia Isatuximab - Aplastic Anemia | Phase 1 / Phase 2 | Recruiting | Institute of Hematology & Blood Diseases Hospital, China | 32 | 2026-06-30 | 2026-09-21 |
Showing 20 of 600. Sign in to see all of them.
Anemia, Sickle Cell (182) · Anemia, Refractory, with Excess of Blasts (101) · Leukemia, Myeloid, Acute (84) · Myelodysplastic Syndromes (78) · Anemia, Aplastic (66) · Leukemia (57) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (57) · Leukemia, Myelomonocytic, Chronic (52) · Myeloproliferative Disorders (35) · beta-Thalassemia (35) · Leukemia, Lymphocytic, Chronic, B-Cell (34) · Thalassemia (33) · Blast Crisis (30) · Fanconi Anemia (30)
Hemic and Lymphatic Diseases (600) · Hematologic Diseases (580) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (291) · Anemia, Hemolytic (266) · Genetic Diseases, Inborn (252) · Bone Marrow Diseases (240) · Anemia, Hemolytic, Congenital (217) · Hemoglobinopathies (200) · Pathological Conditions, Signs and Symptoms (163) · Pathologic Processes (151) · Neoplasms (137) · Neoplasms by Histologic Type (131) · Disease Attributes (127) · Immune System Diseases (125)
Cyclophosphamide (36) · fludarabine phosphate (35) · Whole-Body Irradiation (29) · Mycophenolic Acid (25) · Cyclosporine (24) · fludarabine (24) · Sirolimus (21) · Peripheral Blood Stem Cell Transplantation (20) · Alemtuzumab (19) · Filgrastim (18) · Hydroxyurea (16) · Antilymphocyte Serum (13) · Granulocyte Colony-Stimulating Factor (11) · Tacrolimus (11) · plerixafor (11)
National Heart, Lung, and Blood Institute (NHLBI) (32) · Fred Hutchinson Cancer Center (18) · National Cancer Institute (NCI) (18) · GlaxoSmithKline (15) · Institute of Hematology & Blood Diseases Hospital, China (13) · Baylor College of Medicine (9) · Children's Hospital Medical Center, Cincinnati (7) · City of Hope Medical Center (7) · M.D. Anderson Cancer Center (7) · Masonic Cancer Center, University of Minnesota (6) · Memorial Sloan Kettering Cancer Center (6) · Pfizer (6) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (6) · Amgen (5) · Bellicum Pharmaceuticals (5)
United States (384) · China (63) · United Kingdom (37) · Canada (17) · France (17) · Italy (17) · Australia (15) · Germany (14) · Spain (10) · Brazil (8) · South Korea (8) · Japan (6) · Netherlands (6) · Thailand (6) · Lebanon (5)
John F Tisdale, M.D. (10) · Brenda Sandmaier (4) · Adrianna Vlachos, MD (3) · Carla Washington, PhD (3) · David Diemert, MD (3)
PMID 36240296, PMID 42133908, PMID 24916507, PMID 25824692, PMID 26589907, PMID 28464026, PMID 29669226, PMID 30957581, PMID 32499241, PMID 34175041, PMID 34724566, PMID 36005278, PMID 36860093, PMID 36975201, PMID 37254256, PMID 38866240, PMID 40308078, PMID 40891510, PMID 41871072, PMID 12114413, PMID 12957457, PMID 15570084, PMID 16278404, PMID 17536019, PMID 17620452, PMID 17640728, PMID 18191732, PMID 18299450, PMID 18439858, PMID 18550886, PMID 19139736, PMID 19179301, PMID 19208097, PMID 19786617, PMID 19840322, PMID 20007560, PMID 20071660, PMID 20117846, PMID 20236457, PMID 20644039, PMID 20732454, PMID 20797926, PMID 20858843, PMID 20876669, PMID 20936416, PMID 21149673, PMID 21325598, PMID 21403127, PMID 21477202, PMID 21742281
2014 (7), P30CA015704 (7), 2023 (6), U01CA062461 (6), P30CA006973 (5), 2017 (4), P01CA044991 (4), 2019 (3), P01CA015396 (3), P01CA018029 (3), P01CA078902 (2), P30CA016058 (2), P30CA016672 (2), P30CA033572 (2), R01CA067803 (2)