13 completed, 7 recruiting, 3 not yet recruiting, 2 terminated. 10 Phase 2, 8 Phase 3, 5 Not applicable, 2 Phase 4, 1 Phase 1.
Follow Allergic Bronchopulmonary Aspergillosis: new trials by email Literature Review of Allergic Bronchopulmonary Aspergillosis trials Research Report on Allergic Bronchopulmonary Aspergillosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Real-World Effectiveness of Depemokimab in Allergic Bronchopulmonary Aspergillosis With Severe Eosinophilic Asthma Depemokimab - Allergic Bronchopulmonary Aspergillosis, ABPA | Not applicable | Not yet recruiting | Qianfoshan Hospital | 10 | 2026-11-01 | 2026-09-24 |
| Real-World Effectiveness of Tezepelumab in Allergic Bronchopulmonary Aspergillosis Tezepelumab - Allergic Bronchopulmonary Aspergillosis, Severe Asthma | Not applicable | Not yet recruiting | Qianfoshan Hospital | 10 | 2026-09-01 | 2026-08-11 |
| A Study of the Efficacy and Safety of Bronchoscopic Airway Clearance and Amphotericin B Spraying in Patients With ABPA The patients were treated with bronchoscopic airway clearance and amphotericin B spraying - ABPA, Allergic Bronchopulmonary Aspergillosis | Recruiting | Qianfoshan Hospital | 44 | 2026-01-10 | 2026-01-23 | |
| Real-World Effectiveness of Benralizumab in Allergic Bronchopulmonary Aspergillosis Fasenra - Allergic Bronchopulmonary Aspergillosis, Severe Asthma | Recruiting | Qianfoshan Hospital | 20 | 2025-09-01 | 2026-04-21 | |
| Fungal Status and Prognosis in ABPA ABPA, Allergic Bronchopulmonary Aspergillosis | Recruiting | Qianfoshan Hospital | 114 | 2025-07-01 | 2026-07-08 | |
| iMagIng pulmonaRy Aspergillosis Using Gallium-68-dEferoxamine Radiopharmaceutical: gallium-68-deferoxamine ([68Ga]Ga-DFO-B) - Pulmonary Aspergillosis, Chronic Pulmonary Aspergillosis | Phase 2 | Completed | Radboud University Medical Center | 10 | 2025-05-01 | 2026-08-18 |
| A Cohort Study of the Efficacy and Safety of Biologics in Patients With ABPA Biologic Agent - ABPA, Biologics | Recruiting | Qianfoshan Hospital | 50 | 2025-01-31 | 2026-04-17 | |
| Multicenter Registration Study on Allergic Bronchopulmonary Aspergillosis Allergic Bronchopulmonary Aspergillosis | Not yet recruiting | Peking University Third Hospital | 300 | 2024-10-15 | 2024-10-16 | |
| Allergic Bronchopulmonary Aspergillosis Prescreening Study Allergic Bronchopulmonary Aspergillosis, Asthma | Withdrawn | Community Pharmacology Services Ltd | 2024-01-10 | 2024-01-16 | ||
| A Randomized Trial of Prednisolone, Itraconazole, or Their Combination in Allergic Bronchopulmonary Aspergillosis Prednisolone, Itraconazole - Allergic Bronchopulmonary Aspergillosis | Phase 3 | Recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 300 | 2023-12-01 | 2025-02-28 |
| Oral Itraconazole Versus Combination of Systemic Glucorticoids and Oral Itraconazole in CPA-ABPA Overlap Syndrome Prednisone tablet and Itraconazole, Oral itraconazole - Chronic Pulmonary Aspergillosis, Allergic Bronchopulmonary Aspergillosis | Not applicable | Recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 104 | 2022-06-15 | 2026-04-07 |
| A Prospective Study on Optimizing Treatment for ABPA Prednisone tablet, itraconazole, Omalizumab - Allergic Bronchopulmonary Aspergillosis | Not applicable | Unknown | Shanghai Zhongshan Hospital | 100 | 2021-11-15 | 2021-11-22 |
| Immune Profiles in CF Fungal Infection Cystic Fibrosis, Fungal Infection | Completed | University of Alabama at Birmingham | 24 | 2021-02-10 | 2024-07-18 | |
| ML-Based ABPA Recurrence Prediction and Clinical Utility ABPA, Allergic Bronchopulmonary Aspergillosis | Recruiting | Qianfoshan Hospital | 200 | 2021-01-01 | 2026-07-20 | |
| Investigating Treatment With Dupilumab in Patients With Allergic Bronchopulmonary Aspergillosis (ABPA) (LIBERTY ABPA AIRED) dupilumab, Placebo - Allergic Bronchopulmonary Aspergillosis | Phase 2 | Completed | Regeneron Pharmaceuticals | 62 | 2020-09-15 | 2025-04-04 |
| Phase 1 Three Part SAD, MAD & Cross-Over Study of ZP-059 in Healthy and Asthmatic Subjects Voriconazole inhaled, oral voriconazole - Allergic Bronchopulmonary Aspergillosis | Phase 1 | Completed | Zambon SpA | 58 | 2020-02-11 | 2021-11-15 |
| Deflazacort Vs. Prednisolone in Acute-stage ABPA Deflazacort, Prednisolone - Allergic Bronchopulmonary Aspergillosis | Phase 2 / Phase 3 | Active not recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 150 | 2020-01-15 | 2025-02-28 |
| Benralizumab in the Treatment of Patients With Severe Asthma With ABPA Fasenra, 30 Mg/mL Subcutaneous Solution - ABPA, Severe Asthma | Phase 4 | Withdrawn | Baylor Research Institute | 2019-12-23 | 2022-02-01 | |
| Study in Adult Asthmatic Patients With Allergic Bronchopulmonary Aspergillosis PUR1900, Placebo - Allergic Bronchopulmonary Aspergillosis | Phase 2 | Terminated | Pulmatrix Inc. | 7 | 2019-07-31 | 2021-08-27 |
| Study to Evaluate the Efficacy and Safety of Ibrexafungerp in Patients With Fungal Diseases That Are Refractory to or Intolerant of Standard Antifungal Treatment Ibrexafungerp - Invasive Candidiasis, Mucocutaneous Candidiasis | Phase 3 | Completed | Scynexis, Inc. | 233 | 2017-04-01 | 2024-11-20 |
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Aspergillosis, Allergic Bronchopulmonary (30) · Asthma (7) · Cystic Fibrosis (4) · Invasive Pulmonary Aspergillosis (4) · Pulmonary Aspergillosis (2) · Aspergillosis (1) · Blastomycosis (1) · Bronchiectasis (1) · Candidiasis, Chronic Mucocutaneous (1) · Candidiasis, Invasive (1) · Candidiasis, Vulvovaginal (1) · Coccidioidomycosis (1) · Histoplasmosis (1) · Lung Diseases, Fungal (1) · Mycoses (1)
Bacterial Infections and Mycoses (30) · Hypersensitivity (30) · Hypersensitivity, Immediate (30) · Immune System Diseases (30) · Infections (30) · Lung Diseases (30) · Respiratory Hypersensitivity (30) · Respiratory Tract Diseases (30) · Respiratory Tract Infections (30) · Aspergillosis (29) · Lung Diseases, Fungal (29) · Mycoses (29) · Pulmonary Aspergillosis (28) · Bronchial Diseases (8) · Lung Diseases, Obstructive (7)
Itraconazole (6) · Prednisolone (4) · Glucocorticoids (3) · Azoles (2) · Omalizumab (2) · Prednisone (2) · Voriconazole (2) · benralizumab (2) · Biological Factors (1) · Cholecalciferol (1) · Steroids (1) · deflazacort (1) · dupilumab (1) · ibrexafungerp (1) · liposomal amphotericin B (1)
Post Graduate Institute of Medical Education and Research, Chandigarh (8) · Qianfoshan Hospital (7) · University of Pittsburgh (2) · Baylor Research Institute (1) · Community Pharmacology Services Ltd (1) · Novartis Pharmaceuticals (1) · Peking University Third Hospital (1) · Poitiers University Hospital (1) · Pulmatrix Inc. (1) · Radboud University Medical Center (1) · Regeneron Pharmaceuticals (1) · Scynexis, Inc. (1) · Shanghai Zhongshan Hospital (1) · TFF Pharmaceuticals, Inc. (1) · University of Alabama at Birmingham (1)
India (9) · China (8) · United States (7) · United Kingdom (6) · Netherlands (4) · Germany (3) · France (2) · Poland (2) · Australia (1) · Austria (1) · Belgium (1) · Bulgaria (1) · Hungary (1) · Italy (1) · Japan (1)
Jay K Kolls, MD (2) · Ritesh Agarwal, MD, DM (2) · David Denning, FRCP, FRC Path, FIDSA, FMedSci (1) · Joseph M Pilewski, MD (1) · Margaret Wasilewski, MD (1) · Meiling Jin, MD (1) · Qian Qi (1) · Sukh Dave Singh, Prof, MD, (1) · Thomas S Poore, MD (1) · William J. Calhoun, MD (1) · Yolanda Mageto, MD (1)
PMID 33027187, PMID 26302738, PMID 26585431, PMID 27011794, PMID 29331473, PMID 30049743, PMID 34764182, PMID 38387646, PMID 39918069, PMID 42845221
2019 (2), P50HL084932 (2), 2017 (1), 2023 (1)