15 completed, 10 active not recruiting, 7 terminated, 5 unknown. 22 Phase 1, 13 Phase 2, 9 Not applicable, 3 Phase 3, 2 Early Phase 1.
Follow Advanced Malignant Neoplasm: new trials by email Literature Review of Advanced Malignant Neoplasm trials Research Report on Advanced Malignant Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Trial to Evaluate Effect of IAP0971 in Patients With Advanced Malignant Tumors IAP0971 - Advanced Malignant Neoplasm, Advanced or Metastatic Non-small Cell Lung Cancer | Phase 1 / Phase 2 | Recruiting | SUNHO（China）BioPharmaceutical CO., Ltd. | 78 | 2024-12-31 | 2025-01-15 |
| A Study to Evaluate the Efficacy and Safety of QLF31907 Combination Therapy in Patients With Advanced Malignant Tumors QLF31907, Irinotecan, Docetaxel - Advanced Malignant Neoplasm | Phase 1 / Phase 2 | Not yet recruiting | Qilu Pharmaceutical Co., Ltd. | 60 | 2024-06-15 | 2024-05-01 |
| TQB2928 Injection Combined With Penpulimab in Treatment of Advanced Malignant Tumors. TQB2928 injection, Penpulimab - Advanced Malignant Neoplasm | Phase 1 | Terminated | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 3 | 2024-05-24 | 2024-08-06 |
| A Clinical Trial of TQB3006 Tablets in Patients With Advanced Malignant Cancer TQB3006 tablets - Advanced Malignant Neoplasm | Phase 1 | Completed | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 27 | 2024-04-25 | 2025-05-22 |
| A Study to Evaluate Drug-Drug Interaction of TQB3909 Tablets TQB3909 tablets, Itraconazole capsule, Rifampicin capsule - Advanced Malignant Neoplasm | Phase 1 | Unknown | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 40 | 2023-12-01 | 2023-12-12 |
| A Clinical Trial of TQB3015 Tablets in Patients With Advanced Malignant Cancer TQB3015 tablets - Advanced Malignant Neoplasm | Phase 1 | Withdrawn | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2023-12-01 | 2023-12-29 | |
| A Phase 1 Clinical Trial of AUR106 in Patients With Relapsed Advanced Malignancies AUR106 - Relapse, Advanced Malignant Neoplasm | Phase 1 | Terminated | Aurigene Discovery Technologies Limited | 21 | 2023-08-26 | 2026-04-17 |
| A Clinical Study of TQB3912 Tablets in Patients With Advanced Malignant Tumor TQB3912 tablets - Advanced Malignant Neoplasm | Phase 1 | Completed | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 36 | 2023-08-16 | 2025-08-11 |
| Clinical Application of Lutetium [177Lu]-Catalase in Tumor Radionuclide Therapy [ Lu-177]-Catalase - Advanced Malignant Neoplasm | Early Phase 1 | Unknown | Peking University Cancer Hospital & Institute | 10 | 2023-07-06 | 2023-08-14 |
| Clinical Trial Evaluating the Safety of the TQB2103 for Injection TQB2103 for injection - Advanced Malignant Neoplasm | Phase 1 | Unknown | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | 71 | 2023-07-04 | 2023-07-10 |
| A Clinical Study of 6MW3211 Injection in the Treatment of Advanced Malignant Neoplasm Intravenous Infusion - Advanced Malignant Neoplasm | Phase 1 / Phase 2 | Unknown | Mabwell (Shanghai) Bioscience Co., Ltd. | 272 | 2021-09-27 | 2022-05-09 |
| The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE) rezatapopt, pembrolizumab - Advanced Solid Tumor, Advanced Malignant Neoplasm | Phase 1 / Phase 2 | Recruiting | PMV Pharmaceuticals, Inc | 300 | 2020-10-29 | 2026-10-02 |
| A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies AMXI-5001:Dose Escalation Phase I, AMXI-5001:Dose Expansion Phase II - Advanced Malignant Neoplasm, Breast Cancer | Phase 1 / Phase 2 | Recruiting | AtlasMedx, Incorporated | 122 | 2020-08-12 | 2025-05-01 |
| Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer Bevacizumab, Fluorouracil, Leucovorin - Advanced Malignant Neoplasm, Colorectal Carcinoma Metastatic in the Liver | Phase 1 | Terminated | M.D. Anderson Cancer Center | 38 | 2020-06-23 | 2026-07-27 |
| Cordotomy in Reducing Pain in Patients With Advanced Cancer Cordotomy, Morphine, Questionnaire Administration - Advanced Malignant Neoplasm | Not applicable | Active not recruiting | M.D. Anderson Cancer Center | 27 | 2019-09-16 | 2026-09-16 |
| First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia Ziftomenib, Midazolam, Itraconazole - Advanced Malignant Neoplasm, Acute Myeloid Leukemia | Phase 1 / Phase 2 | Active not recruiting | Kura Oncology, Inc. | 263 | 2019-09-12 | 2026-05-13 |
| Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study Biospecimen Collection - Advanced Malignant Neoplasm, Advanced Melanoma | Completed | National Cancer Institute (NCI) | 64 | 2019-07-16 | 2026-02-04 | |
| Financial Distress in Advanced Cancer Patients Medical Chart Review, Quality-of-Life Assessment, Questionnaire Administration - Advanced Malignant Neoplasm, Locally Advanced Malignant Neoplasm | Active not recruiting | M.D. Anderson Cancer Center | 141 | 2019-07-02 | 2026-10-06 | |
| Videos and Questionnaires in Assessing Patient Perception of Physician's Compassion, Communication Skills, and Professionalism During Clinic Visits Questionnaire Administration, Video - Advanced Malignant Neoplasm, Locally Advanced Malignant Neoplasm | Not applicable | Completed | M.D. Anderson Cancer Center | 125 | 2019-03-30 | 2024-09-19 |
| Caregiver Burden, Quality of Life, and Symptom Distress at Different Palliative Cancer Care Settings Quality-of-Life Assessment, Questionnaire Administration - Advanced Malignant Neoplasm, Locally Advanced Malignant Neoplasm | Completed | M.D. Anderson Cancer Center | 351 | 2019-03-26 | 2022-03-03 |
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Neoplasm Metastasis (15) · Recurrence (14) · Neoplasms (10) · Breast Neoplasms (4) · Carcinoma, Non-Small-Cell Lung (4) · Ovarian Neoplasms (4) · Prostatic Neoplasms (4) · Colorectal Neoplasms (3) · Carcinoma, Transitional Cell (2) · Endometrial Neoplasms (2) · Fatigue (2) · Head and Neck Neoplasms (2) · Lung Neoplasms (2) · Pancreatic Neoplasms (2) · Brain Neoplasms (1)
Pathological Conditions, Signs and Symptoms (21) · Pathologic Processes (19) · Disease Attributes (15) · Neoplasms (15) · Neoplastic Processes (15) · Neoplasms by Site (11) · Digestive System Diseases (6) · Digestive System Neoplasms (6) · Endocrine System Diseases (6) · Female Urogenital Diseases (6) · Female Urogenital Diseases and Pregnancy Complications (6) · Male Urogenital Diseases (6) · Neoplasms by Histologic Type (6) · Urogenital Diseases (6) · Urogenital Neoplasms (6)
Bevacizumab (2) · Disulfides (2) · Everolimus (2) · Immunoglobulin G (2) · Itraconazole (2) · Sirolimus (2) · Sorafenib (2) · temsirolimus (2) · Acetates (1) · Analgesia (1) · Calcium Dobesilate (1) · Cetuximab (1) · Chlorpromazine (1) · Clinical Trials, Phase I as Topic (1) · Clinical Trials, Phase II as Topic (1)
M.D. Anderson Cancer Center (17) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (5) · Kura Oncology, Inc. (2) · Mayo Clinic (2) · National Cancer Institute (NCI) (2) · Academic and Community Cancer Research United (1) · AtlasMedx, Incorporated (1) · Aurigene Discovery Technologies Limited (1) · Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. (1) · Chinese Medical Doctor Association (1) · Deciphera Pharmaceuticals, LLC (1) · ECOG-ACRIN Cancer Research Group (1) · Fred Hutchinson Cancer Center (1) · Mabwell (Shanghai) Bioscience Co., Ltd. (1) · PMV Pharmaceuticals, Inc (1)
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Sriram Yennu (3) · Filip Janku (2) · Sarina A Piha-Paul (2) · Ahsan Azhar (1) · Akhil Kumar, MD (1) · Ali Haider, MD (1) · Aminah Jatoi (1) · Aminah Jatoi, M.D. (1) · Angela Bradbury (1) · David Hong (1) · David Hui (1) · Eduardo Bruera (1) · Elizabeth Loggers (1) · Frances Lewis (1) · Heidi Klepin (1)
PMID 23676418, PMID 25982012, PMID 32479786, PMID 33741715, PMID 33867481, PMID 34267079, PMID 34890045, PMID 34965510, PMID 37129892, PMID 37311055, PMID 39362248, PMID 40543428, PMID 40932470, PMID 40997296, PMID 41389341, PMID 41740031
P30CA016672 (6), P30CA015083 (2), P30CA015704 (2), P30CA012197 (1), P30CA016058 (1), R01NR018481 (1), R21NR016736 (1), U01CA062461 (1), UG1CA189823 (1)