6 recruiting, 3 completed, 2 active not recruiting, 2 not yet recruiting. 7 Not applicable, 3 Phase 2, 1 Early Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 3, Active not recruiting 2, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 3 | Recruiting 3 |
| Early Phase 1 | 1 | Not yet recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow this condition Literature Review of Adaptive Radiotherapy trials Research Report on Adaptive Radiotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Response With Interim PSMA PET in Metastatic Castration-sensitive Prostate Cancer for Optimization of Adaptive Metastasis-directed Radiotherapy Delivery Drug: 68-Ga PSMA11, Adaptive stereotactic ablative radiotherapy (SABR), 68Ga-PSMA-11 - Prostate Cancer, Castration Sensitive Prostate Cancer | Early Phase 1 | Not yet recruiting | University of Texas Southwestern Medical Center | 30 | 2026-10-01 | 2026-08-24 |
| Glioma Adaptive Radiotherapy With Development of an Artificial Intelligence Workflow Adaptive radiotherapy - Diffuse Glioma, Glioblastoma | Phase 2 | Recruiting | Tata Memorial Centre | 60 | 2026-07-27 | 2026-08-17 |
| Ultrahypofractionated, Adaptive Radiation Therapy of Prostate Cancer Prostate Cancer, Adaptive Radiotherapy | Recruiting | Jena University Hospital | 150 | 2026-04-01 | 2026-06-11 | |
| The Efficacy and Safety of the Combination of PD-1 With Chemotherapy and Adaptive Radiotherapy Strategy in the Treatment of Stage III Non-small Cell Lung Cancer Patients Experimental - NSCLC, Sintilimab | Phase 2 | Recruiting | The Third Xiangya Hospital of Central South University | 35 | 2025-08-29 | 2026-09-02 |
| the Efficacy of MR-guided Online Adaptive Radiotherapy for Locally Advanced Rectal Cancer short course radiotherapy using MR-linac - Rectal Cancer, Adaptive Radiotherapy | Not applicable | Not yet recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 49 | 2025-08-01 | 2025-07-23 |
| Moderated Hypofractionated Online Adaptive Radiotherapy in Cervical Cancer Moderated hypofractionated online adaptive radiotherapy, Conventional radiotherapy - Cervical Cancer, Adaptive Radiotherapy | Phase 3 | Recruiting | Peking Union Medical College Hospital | 440 | 2024-11-19 | 2025-03-18 |
| Efficiency of Contemporary Off-line Adaptive Radiotherapy for Lung Cancer CBCT-based adaptive radiotherapy - NSCLC (Advanced Non-small Cell Lung Cancer), Adaptive Radiotherapy | Not applicable | Active not recruiting | Universitaire Ziekenhuizen KU Leuven | 30 | 2024-06-21 | 2026-09-16 |
| Elimination of PTV Margins Based on Online Adaptive Stereotactic Radiotherapy for Early-stage Non-small Cell Lung Cancer or Pulmonary Oligometastases Online adaptive SBRT, Conventional SBRT - Adaptive Radiotherapy, Stereotactic Body Radiotherapy | Phase 2 | Recruiting | Sun Yat-sen University | 130 | 2024-05-22 | 2025-11-17 |
| Adaptive Radiotherapy in Head and Neck Tumor Patients Adaptive Radiotherapy, image guided radiotherapy without online adaptation - Head and Neck Neoplasms, Head and Neck Cancer | Not applicable | Completed | University Hospital, Essen | 30 | 2024-01-25 | 2026-10-20 |
| Adaptive Radiotherapy in Patients With Gynecological Tumors Adaptive Radiotherapy - Gynecological Tumor, Adaptive Radiotherapy | Not applicable | Completed | University Hospital, Essen | 30 | 2024-01-15 | 2026-10-20 |
| Prospective Validation of Adaptive Radiotherapy (ART) in Patients With Head and Neck Tumors Adaptive Radiotherapy - Head and Neck Cancer, Adaptive Radiotherapy | Not applicable | Completed | University Hospital, Essen | 30 | 2023-11-15 | 2026-10-20 |
| Moderately Hypofractionated Adaptive Radiotherapy for Cervical Cancer Moderately hypofractionated adaptive radiotherapy (ART)+ High-dose rate (HDR) Brachytherapy - Cervical Neoplasm, Adaptive Radiotherapy | Not applicable | Active not recruiting | Peking Union Medical College Hospital | 30 | 2023-09-19 | 2025-06-08 |
| MR-linac Guided Ultra-hypofractionated RT for Prostate Cancer (SMART-P01 and SMART-P02) MR-linac - Prostate Cancer, Radiotherapy Side Effect | Not applicable | Recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 50 | 2021-02-01 | 2025-12-11 |
Carcinoma, Non-Small-Cell Lung (3) · Prostatic Neoplasms (3) · Uterine Cervical Neoplasms (3) · Head and Neck Neoplasms (2) · Radiation Injuries (2) · Glioblastoma (1) · Neoplasm Metastasis (1) · Rectal Neoplasms (1)
Neoplasms (13) · Neoplasms by Site (12) · Genital Diseases (6) · Urogenital Diseases (6) · Urogenital Neoplasms (6) · Bronchial Neoplasms (3) · Carcinoma, Bronchogenic (3) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Genital Diseases, Female (3) · Genital Diseases, Male (3) · Genital Neoplasms, Female (3) · Genital Neoplasms, Male (3) · Lung Diseases (3) · Lung Neoplasms (3)
Brachytherapy (1) · Radiotherapy, Image-Guided (1) · gallium 68 PSMA-11 (1)
University Hospital, Essen (3) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (2) · Peking Union Medical College Hospital (2) · Jena University Hospital (1) · Sun Yat-sen University (1) · Tata Memorial Centre (1) · The Third Xiangya Hospital of Central South University (1) · Universitaire Ziekenhuizen KU Leuven (1) · University of Texas Southwestern Medical Center (1)
China (5) · Germany (4) · Belgium (1) · India (1) · United States (1)
Archya Dasgupta (1) · Fuquan Zhang, MD (1) · Hui Liu, Professor (1)