7 completed. 7 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 7 |
| Phase 1 | 2 | Completed 2 |
Follow Acute Undifferentiated Leukemia: new trials by email Literature Review of Acute Undifferentiated Leukemia trials Research Report on Acute Undifferentiated Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Fludarabine Phosphate - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 84 | 2015-03-23 | 2026-06-01 |
| Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia Clofarabine, Cytarabine, Dexamethasone - Acute Bilineal Leukemia, Acute Biphenotypic Leukemia | Phase 2 | Completed | M.D. Anderson Cancer Center | 16 | 2014-10-27 | 2024-03-22 |
| Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children Allogeneic Hematopoietic Stem Cell Transplantation, Fludarabine Phosphate, Laboratory Biomarker Analysis - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 20 | 2014-04-10 | 2024-03-12 |
| Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies deferasirox, laboratory biomarker analysis, enzyme-linked immunosorbent assay - Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Wake Forest University Health Sciences | 16 | 2011-01-01 | 2018-09-07 |
| Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer alemtuzumab, total-body irradiation, fludarabine phosphate - Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 12 | 2005-03-01 | 2017-05-30 |
| Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia allopurinol, cyclophosphamide, daunorubicin hydrochloride - Acute Undifferentiated Leukemia, B-cell Adult Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 302 | 2003-06-01 | 2022-05-03 |
| Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer total-body irradiation, fludarabine phosphate, cyclosporine - Acute Undifferentiated Leukemia, Adult Nasal Type Extranodal NK/T-cell Lymphoma | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 21 | 2000-05-01 | 2020-01-21 |
Leukemia, Biphenotypic, Acute (7) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (6) · Leukemia, Myeloid, Acute (5) · Burkitt Lymphoma (3) · Hodgkin Disease (3) · Immunoblastic Lymphadenopathy (3) · Intraocular Lymphoma (3) · Leukemia, Lymphocytic, Chronic, B-Cell (3) · Leukemia, Mast-Cell (3) · Lymphoma, B-Cell, Marginal Zone (3) · Lymphoma, Extranodal NK-T-Cell (3) · Lymphoma, Follicular (3) · Lymphoma, Large B-Cell, Diffuse (3) · Lymphoma, Large-Cell, Anaplastic (3) · Lymphoma, Large-Cell, Immunoblastic (3)
Hematologic Diseases (7) · Hemic and Lymphatic Diseases (7) · Immune System Diseases (7) · Immunoproliferative Disorders (7) · Leukemia (7) · Leukemia, Lymphoid (7) · Lymphatic Diseases (7) · Lymphoproliferative Disorders (7) · Neoplasms (7) · Neoplasms by Histologic Type (7) · Bone Marrow Diseases (5) · Chronic Disease (5) · Disease Attributes (5) · Leukemia, Myeloid (5) · Pathologic Processes (5)
Peripheral Blood Stem Cell Transplantation (4) · Whole-Body Irradiation (4) · fludarabine phosphate (4) · Methotrexate (3) · Mycophenolic Acid (3) · Alemtuzumab (2) · Cyclophosphamide (2) · Cyclosporine (2) · Cytarabine (2) · Dexamethasone (2) · Tacrolimus (2) · Thiotepa (2) · Vincristine (2) · merphos (2) · Acyclovir (1)
Fred Hutchinson Cancer Center (4) · M.D. Anderson Cancer Center (1) · National Cancer Institute (NCI) (1) · Wake Forest University Health Sciences (1)
United States (7) · Italy (2)
Marie Bleakley (2) · Brenda Sandmaier (1) · David Maloney (1) · Elias Jabbour (1) · Mary Ann Knovich, MD (1) · Wendy Stock (1)
P01CA018029 (3), P30CA015704 (2), R01HL121568 (2), K23CA154532 (1), P01CA078902 (1), U10CA031946 (1)