221 trials newly registered, first posted 2026-10-20, by therapeutic area, largest first. Existing trials that posted results or changed status in the past seven days are under their own tabs; routine edits to existing records (sites, contacts, enrollment numbers) are not listed.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
Symptoms and General Pathology 48 Cancers and Other Neoplasms 38 Nervous System Diseases 31 Heart and Blood Diseases 18 Nutritional and Metabolic Diseases 17 Behaviors and Mental Disorders 15 Skin and Connective Tissue Diseases 15 Blood and Lymph Conditions 14 Infections 14 Respiratory Tract (Lung and Bronchial) Diseases 14 Urinary Tract, Sexual Organs, and Pregnancy Conditions 14 Muscle, Bone, and Cartilage Diseases 13 Immune System Diseases 12 Digestive System Diseases 11 Diseases and Abnormalities at or Before Birth 11 Gland and Hormone Related Diseases 10 Mouth and Tooth Diseases 9 Wounds and Injuries 9 Eye Diseases 3 Substance Related Disorders 1 Other 61 Results posted this week 73 Status changes this week 723 All areas
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of LY4167586 in Participants With Obesity or Overweight With or Without Type 2 Diabetes LY4167586, Placebo - Obesity, Overweight | Phase 1 | Not yet recruiting | Eli Lilly and Company | 617 | 2026-10-01 | 2026-10-20 |
| A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacterial Sexually Transmitted Infections (STI) in Young African Women Doxycycline hyclate, Standard of Care for STI prevention - Sexually Transmitted Infection (STI), Gonorrhea | Phase 3 | Not yet recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 580 | 2026-11-30 | 2026-10-20 |
| Psychoactive Drug Use and Acute Care Use After Trauma and Out-of-Hospital Cardiac Arrest Opioids (ATC N02A), Antiepileptics (ATC N03A), Antipsychotics (ATC N05A) - Wounds and Injuries, Out-of-Hospital Cardiac Arrest | Active not recruiting | Azienda Usl di Bologna | 52720 | 2026-06-10 | 2026-10-20 | |
| This Study is the Clinical Validation Study for Validation for the Digital Pathology System 'SGi 1.0 + EPW 1.0 + Compatible Clinical Displays' Digital pathology system - Pathological Processes | Recruiting | Philips Digital & Computational Pathology | 470 | 2026-08-01 | 2026-10-22 | |
| A PHASE 2A, EXPLORATORY, RANDOMIZED, SINGLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY OF WEIGHT LOSS INDUCED BY NKS-3 IN OBESE ADULTS. Investigational product is a modified linoleic acid, named NKS-3. This non-caloric agent, synthetized from linoleic acid, is a fat taste receptors agonist, targeting CD36 with also an impact on GPR120, Placebo solution - Obesity / Overweight, Obesity (BMI Equal to or >30) | Phase 2 | Not yet recruiting | EktaH | 31 | 2026-10-20 | 2026-10-20 |
| RPM Signals in Outpatient CAR T Therapy Cytokine Release Syndrome, Immune Effector Cell-Associated Neurotoxicity Syndrome | Not yet recruiting | Current Health | 125 | 2026-12-01 | 2026-10-20 | |
| Optimizing Antibiotic Prescription in STI Clinics Using Rapid POCT cobas® Liat® CT/NG Point-of-Care Test - Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection | Not applicable | Not yet recruiting | Hospices Civils de Lyon | 404 | 2026-12-01 | 2026-10-20 |
| Energy Dose and Cardioversion Outcomes in AF Synchronized Electrical Cardioversion With Different Energy Strategies, Conventional Step-Up Energy Cardioversion - Atrial Fibrillation (AF) | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 400 | 2026-11-01 | 2026-10-20 |
| Union-LC-MPE Cohort:A Multicenter Cohort Study on Diagnosis and Prognosis of Malignant Pleural Effusion in Lung Cance Malignant Pleural Effusions (Mpe), Lung Cancer (Diagnosis) | Not yet recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 3000 | 2026-10-01 | 2026-10-20 | |
| The Effect of Bitewing Radiography on Outcomes and Costs of Treating Caries in Permanent Teeth Visual-tactile caries examination, Visual-tactile caries examination and bilateral bitewing radiography - Dental Caries, Teeth Loss | Not applicable | Not yet recruiting | Jukka Leinonen | 250 | 2027-03-01 | 2026-10-20 |
| Permanent Versus Slowly Dissolving Stitches for Non-Mesh (Shouldice) Groin Hernia Repair Polypropylene suture (Prolene), Polydioxanone suture (PDS) - Inguinal Hernia | Not applicable | Recruiting | Northwestern University | 200 | 2026-10-01 | 2026-10-20 |
| Reducing Wound Complications in Breast Surgery Using hACM Dehydrated Human Amnion Chorion Membrane - Surgical Wound Healing, Scar Tissue | Phase 4 | Not yet recruiting | Rutgers, The State University of New Jersey | 200 | 2026-11-01 | 2026-10-20 |
| Post-operative Pain and Apical Healing After Root Canal (re)Treatment With Laser-activated Irrigation Versus Sonic or no Activation sonically activated irrigation, laser activated irrigation, conventional needle irrigation - Apical Periodontitis, Post Operative Pain, Acute | Not applicable | Not yet recruiting | University Ghent | 183 | 2026-10-01 | 2026-10-20 |
| Bilateral Pecto-Intercostal Fascial Plane Block for Prevention of Chronic Poststernotomy Pain After CABG Pecto-Intercostal Fascial Plane Block, Standardized Multimodal Systemic Analgesia - Chronic Poststernotomy Pain | Not applicable | Not yet recruiting | Izmir Katip Celebi University | 180 | 2027-01-01 | 2026-10-20 |
| Intravenous Fish Oil Emulsion in Critically Ill Patients With High Inflammatory Status. Omegaven (10% fish-oil emulsion; Fresenius-Kabi) - Critical Illness | Phase 2 | Recruiting | Lee Zheng Yii | 159 | 2026-07-07 | 2026-10-20 |
| Virtual Reality for Pain and Anxiety During Intravenous Catheterization virtual reality glass - VR, Pain | Not applicable | Completed | Erzincan Binali Yildirim Universitesi | 136 | 2025-03-20 | 2026-10-20 |
| Comparison of Two Pulse Field Ablation Systems for AF Ablation Pulse Field Ablation - AF - Atrial Fibrillation | Not applicable | Recruiting | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | 120 | 2026-07-10 | 2026-10-20 |
| Oral Multi-Strain Lactobacillus Probiotic for Women With Vaginal Dysbiosis Low-dose multi-strain Lactobacillus capsule, High-dose capsule, Placebo capsule - Vaginitis, Dysbiosis | Not applicable | Completed | Soon Chun Hyang University | 119 | 2023-05-28 | 2026-10-20 |
| Closed Versus Open Endotracheal Suctioning and Ventilator-Associated Pneumonia in Severe Traumatic Brain Injury Closed endotracheal suction system, Open endotracheal suction - Ventilator-associated Pneumonia, Traumatic Brain Injury | Not applicable | Not yet recruiting | Minia University | 120 | 2026-10-04 | 2026-10-20 |
| Effect of Buzzy and Virtual Reality on Children Undergoing Venous Procedures Vein-imaging device + virtual reality headset group, Vein-imaging device + Buzzy group - Fever, Children | Not applicable | Recruiting | Bandırma Onyedi Eylül University | 105 | 2026-02-06 | 2026-10-20 |
| AI-ECG Detection of Occlusion Myocardial Infarction at Emergency Department Triage (TRIACS) Acute Coronary Syndromes, Chest Pain | Not yet recruiting | University Medical Centre Maribor | 1000 | 2026-10-19 | 2026-10-20 | |
| Haptic-Assisted Virtual Reality Upper-Limb Rehabilitation After Intracerebral Haemorrhage Haptic-assisted virtual reality training (Bimeo PRO), Conventional rehabilitation - Intracerebral Hemorrhage, Hemorrhagic Stroke | Not applicable | Not yet recruiting | University Medical Centre Maribor | 100 | 2026-11-01 | 2026-10-20 |
| Temporal Dynamics of Peripheral SpO₂ During Reoxygenation Voluntary Apnea - Healthy Vollunteer, Apnea | Not applicable | Recruiting | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 100 | 2026-08-03 | 2026-10-20 |
| Impact of Range of Motion Exercises on Pain and Functional Ability Range of Motion exercises - Impact of ROM Exercises on Pain and Functional Ability in Patients With Second -Degree Burns | Not applicable | Not yet recruiting | Al-Azhar University | 80 | 2026-11-01 | 2026-10-20 |
| IGOB131 As A GLP-1 Modulator For Metabolic Disorders In Adults With Obesity IGOB131, Dextrin - Obesity & Overweight | Phase 2 | Not yet recruiting | University of Yaounde 1 | 80 | 2026-12-01 | 2026-10-20 |
| Effects of Irrigation Activation and Obturation Techniques on Pain After Root Canal Treatment Conventional Needle Irrigation, Sonic Irrigation Activation, Cold Lateral Condensation - Symptomatic Irreversible Pulpitis (SIP), Post Operative Pain After Root Canal Therapy | Not applicable | Completed | Biruni University | 72 | 2024-11-04 | 2026-10-20 |
| Ginger-PD: Ginger as a Modifier of Ghrelin Levels and Gut Function in Parkinson's Disease Ginger - REM Sleep Behavior Disorder, Parkinson s Disease | Not applicable | Recruiting | Cambridge University Hospitals NHS Foundation Trust | 72 | 2025-12-17 | 2026-10-21 |
| Perineural Botulinum Toxin Injection Versus Oral Duloxetine in Relief of Foot Pain in Painful Peripheral Diabetic Neuropathy Botulinum Toxin Type A, Duloxetine, Oral Placebo Tablet - Diabetic Peripheral Neuropathy, Painful Diabetic Neuropathy | Phase 2 | Not yet recruiting | Assiut University | 56 | 2026-11-01 | 2026-10-20 |
| Comparison of the Effectiveness of Motor Imagery Exercises and Suboccipital Myofascial Release Techniques in Nonspecific Chronic Neck Pain Active Exercise, Motor Imagery, Suboccipital Myofascial Release - Non-specific Chronic Neck Pain | Not applicable | Not yet recruiting | Ankara Yildirim Beyazıt University | 51 | 2026-11-01 | 2026-10-20 |
| A Behavioral Circuit Breathing Training Intervention on Smoking Cessation and Respiratory Function Among Youth Who Use E-cigarettes Circuit Breathing Intervention, Diaphragmatic Breathing - E Cigarette Use | Not applicable | Recruiting | Chulalongkorn University | 45 | 2026-09-01 | 2026-10-20 |
| Bispecific Antibody-Based Holding/Bridging Therapy Before CAR-T in Aggressive B-Cell Lymphomas Glofitamab, Epcoritamab, Polatuzumab Vedotin - Aggressive B-cell Non-Hodgkin Lymphoma (aNHL), Relapsed or Refractory B-cell Lymphoma | Phase 2 | Recruiting | National Research Center for Hematology, Russia | 40 | 2026-09-01 | 2026-10-20 |
| Outcome Prediction and Recovery After Spontaneous Intracerebral Haemorrhage Intracerebral Hemorrhage, Hemorrhagic Stroke | Not yet recruiting | University Medical Centre Maribor | 300 | 2026-11-01 | 2026-10-20 | |
| Initiation Ropivacaine Dose for Labor Analgesia Via Double Dural Puncture Epidural Technique 0.1% Ropivacaine - Labor Pain | Not applicable | Not yet recruiting | General Hospital of Ningxia Medical University | 30 | 2026-11-01 | 2026-10-20 |
| 15-years Outcomes of Sleeve Gastrectomy on Weight Loss Bariatric Surgery, Sleeve Gastrectomy | Recruiting | Centre Hospitalier Universitaire, Amiens | 300 | 2026-10-06 | 2026-10-20 | |
| Quadriceps Muscle Activation and Oxygenation Responses During Usual Care Compared to Individualized Interval and Constant Work Rate Bed-cycling. An Experimental Study. usual care constant work rate bedcycling, Individualized constant work rate bedcycling, Individualized interval bedcycling - Critical Illness | Not applicable | Not yet recruiting | KU Leuven | 29 | 2026-11-01 | 2026-10-20 |
| Effects of Yerba Mate Supplementation on Metabolic Health, Physical Function, and Cognition in Older Adults With Excess Adiposity Yerba Mate, Placebo - Overweight (BMI > 25), Obesity & Overweight | Not applicable | Completed | University of North Alabama | 25 | 2025-11-15 | 2026-10-20 |
| Targeted Nutritional Intervention (HMB, Arginine, Glutamine) in Patients With Pancreatic Cancer HMB / L-Arginine / L-Glutamine oral nutritional mixture, Standard Dietary Counseling - PDAC, Pancreas Adenocarcinoma (MSI-H) | Not applicable | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 24 | 2026-12-01 | 2026-10-20 |
| Buccal Periosteal Inversion Flap vs Buccal Advancement Flap for Acute Oro-Antral Communication Closure Buccal Periosteal Inversion Flap, Buccal Advancement Flap - Acute Oroantral Communication | Not applicable | Not yet recruiting | Medical University of Graz | 22 | 2026-10-01 | 2026-10-20 |
| Multi-Omics Genetic Investigation Strategies to Enhance the Diagnostic Workflow for Rare Diseases Neurodevelopmental Disorders, Intellectual Disability | Recruiting | Istituto Giannina Gaslini | 200 | 2023-09-04 | 2026-10-20 | |
| Pain After Microsurgical Decompression LUMBAR STENOSIS | Enrolling by invitation | Aalborg University | 200 | 2026-11-01 | 2026-10-20 | |
| Postoperative Pain Trajectories After Endometriosis Surgery Perioperative quantitative sensory testing, questionnaire - Endometriosis, Postoperative Pain | Recruiting | Centre Hospitalier Universitaire, Amiens | 150 | 2026-07-07 | 2026-10-20 | |
| Phase I Safety Clinical Trial of Anti-CD19 CAR-T Therapy COL01 for the Treatment of Adults With Relapsed or Refractory B-cell Lymphoid Neoplasms: First-in-human Administration, COLIBRI. CAR-T anti-CD19 COL01 - Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia, Lymphoid Malignancies | Phase 1 | Not yet recruiting | GUSTAVO SALGUERO | 12 | 2027-04-01 | 2026-10-20 |
| Motion Capture in Box and Bloks Test Inertial Measurement Unit and Box and Block test - Healthy, Parkinson Disease | Completed | IRCCS San Raffaele Roma | 105 | 2020-01-12 | 2026-10-20 | |
| Effects of Adding Motor Imagery Training to Exercise on Pain, Fibromyalgia Impact, and Kinesiophobia in Women With Fibromyalgia: a Randomized Controlled Trial Motor imagery - Pain Management, Fibromyalgia | Completed | Ufuk University | 100 | 2021-05-01 | 2026-10-20 | |
| Powered Exoskeleton-Assisted Walking in Persons With Spinal Cord Injury Wearable Powered Exoskeleton - Spinal Cord Injuries (SCI), Muscle Spasticity as a Result of Spinal Cord Injury | Completed | IRCCS San Raffaele Roma | 74 | 2024-09-01 | 2026-10-20 | |
| Impact of Nutritional Status Before Joint Replacement on Infection Risk Periprosthetic Joint Infection (PJI), Malnutitrion | Not yet recruiting | Assiut University | 50 | 2026-12-01 | 2026-10-20 | |
| Multimodal Characterization of Movement Trajectories in Chronic Inflammatory Demyelinating Polyneuropathy Xsens motion suit - CIDP - Chronic Inflammatory Demyelinating Polyneuropathy | Not yet recruiting | Heinrich-Heine University, Duesseldorf | 50 | 2026-10-01 | 2026-10-20 | |
| Diagnostic Work-up of Nephrocalcinosis in Children Nephrocalcinosis | Not yet recruiting | Assiut University | 40 | 2026-10-20 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Development and Multi-Centre Validation of a Novel Non-Invasive Melanoma Molecular Diagnostic Test Melanoma | Recruiting | Mitra Bio | 2000 | 2026-06-10 | 2026-10-21 | |
| A Study to Evaluate Treatment Patterns and Investigate Adult Patients With B-cell Lymphoma Lymphoma, B-Cell | Not yet recruiting | AstraZeneca | 532 | 2026-11-30 | 2026-10-20 | |
| GRACE-DE: Prospective Multicenter Real-world Gastric Cancer Patients Starting AZ-developed and Approved Drugs in Germany (Umbrella Study) Gastric Cancer, Gastroesophageal Junction Cancer | Not yet recruiting | AstraZeneca | 300 | 2026-10-31 | 2026-10-20 | |
| Epcoritamab as Consolidative Therapy for Waldenstr(SqrRoot)(Delta)m Macroglobulinemia (WM) Treated With a Bruton Tyrosine Kinase Inhibitor (BTKi) epcoritamab - Waldenstrom Macroglobulinemia | Phase 2 | Not yet recruiting | National Heart, Lung, and Blood Institute (NHLBI) | 24 | 2026-10-27 | 2026-10-22 |
| RPM Signals in Outpatient CAR T Therapy Cytokine Release Syndrome, Immune Effector Cell-Associated Neurotoxicity Syndrome | Not yet recruiting | Current Health | 125 | 2026-12-01 | 2026-10-20 | |
| Role of Artificial Intelligence in Breast Cancer Screening Via Mammography Transpara software - Breast Cancer | Not applicable | Not yet recruiting | Centre Antoine Lacassagne | 1222 | 2027-01-31 | 2026-10-20 |
| Thymalfasin Combined With Chemotherapy and Immunotherapy in TNBC Neoadjuvant Treatment Thymalfasin - Breast Cancer, TNBC - Triple-Negative Breast Cancer | Phase 2 | Not yet recruiting | Fudan University | 572 | 2026-11-08 | 2026-10-20 |
| Union-LC-MPE Cohort:A Multicenter Cohort Study on Diagnosis and Prognosis of Malignant Pleural Effusion in Lung Cance Malignant Pleural Effusions (Mpe), Lung Cancer (Diagnosis) | Not yet recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 3000 | 2026-10-01 | 2026-10-20 | |
| SALI-10 Probiotic to Reduce Osteoradionecrosis and Dental Toxicity Following Radiation Therapy for Head and Neck Cancer Standard of Care (SOC), Experimental drug - Head and Neck Cancer | Phase 3 | Not yet recruiting | University Health Network, Toronto | 288 | 2026-11-01 | 2026-10-20 |
| Surgical Margin Assessment Using Intra-operative High-resolution PET/CT in Patients With Cancers Referred to Surgical Resection, an Exploratory Pilot Study FDG radiotracer - Breast Cancer, Head and Neck Cancers | Not applicable | Active not recruiting | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 250 | 2026-07-20 | 2026-10-20 |
| EXercise-induced PhysioLogical Adaptations In Neurological Disorders Acute Exercise - Epilepsy, Functional Neurological Disorder | Not applicable | Recruiting | Brigham and Women's Hospital | 240 | 2026-07-22 | 2026-10-20 |
| AI Analysis of CT Scans to Classify Ovarian Tumours as Benign, Borderline or Malignant Before Surgery Ovarian Cancer, Ovarian Tumor | Not yet recruiting | Catharina Ziekenhuis Eindhoven | 1300 | 2026-11-01 | 2026-10-20 | |
| Immunonutrition for Surgical Prehabilitation of Patients With Upper GI Cancer Oral nutritional supplements with immunonutrition (enriched with arginine, nucleotides, vitamin D and omega-3-fatty acid), Standart of care - Upper GI Cancer | Not applicable | Enrolling by invitation | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | 110 | 2026-01-01 | 2026-10-20 |
| Diagnostic Performance of an AI-Based Multi-Omics Model for Early Lung Cancer Pulmonary Nodules, Early Detection of Cancer | Not yet recruiting | Beijing Chao Yang Hospital | 1050 | 2026-10-21 | 2026-10-20 | |
| Biomarker Investigation for Early Gastric Cancer Detection Saliva sampling, Gastric juice sampling, Blood sampling - Gastro Oesophageal Cancer | Not applicable | Not yet recruiting | Centre Leon Berard | 100 | 2026-11-01 | 2026-10-20 |
| HRT-PC Trial: Hormone Recovery After Treatment for Prostate Cancer Trial. An Open-label Phase II Study of Clomiphene Citrate in Patients With Persistent Hypogonadism After ADT for Treatment of Localized Prostate Cancer Clomiphene Citrate 25mg - Prostate Cancer | Phase 2 | Not yet recruiting | University of Nebraska | 83 | 2027-01-31 | 2026-10-20 |
| Effects of Web-Based Ovarian Cancer Awareness Education on Women's Health Beliefs and Risk-Reducing Behaviors Web-Based Ovarian Cancer Awareness Education, General Reproductive Health Information - Ovarian Cancer | Not applicable | Not yet recruiting | Ege University | 82 | 2026-11-01 | 2026-10-22 |
| Podcast-Based Psychosocial Support for Women Newly Diagnosed With Breast Cancer Psychosocial Support Program - Breast Cancer | Not applicable | Not yet recruiting | Mei Man | 80 | 2026-10-15 | 2026-10-20 |
| 27-Inch Versus 55-Inch Monitors in Women Undergoing Endometrial Cancer Surgery 27-Inch Endoscopic Imaging Monitor, 55-Inch Endoscopic Imaging Monitor - Endometrial Cancer | Not applicable | Not yet recruiting | Metehan Uzundal | 70 | 2026-10-01 | 2026-10-20 |
| Effect of ACTIVE-Care on Cancer-Related Fatigue, Hope, and Psychological Resilience in Adolescents With Acute Lymphoblastic Leukemia ACTIVE-Care Integrated Physical Activity-Based Supportive Care Program - Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Adolescent | Not applicable | Completed | Selcuk University | 70 | 2026-07-01 | 2026-10-20 |
| Radiotherapy for Gynecologic Cancer With Up to 10 Active Metastatic Lesions Routine-care metastasis-directed radiotherapy - Cervical Cancer, Gynecologic Cancer | Recruiting | Affidea Nu-med Center of Oncological DIagnostics and Therapy | 500 | 2026-10-06 | 2026-10-20 | |
| Bispecific Antibody-Based Holding/Bridging Therapy Before CAR-T in Aggressive B-Cell Lymphomas Glofitamab, Epcoritamab, Polatuzumab Vedotin - Aggressive B-cell Non-Hodgkin Lymphoma (aNHL), Relapsed or Refractory B-cell Lymphoma | Phase 2 | Recruiting | National Research Center for Hematology, Russia | 40 | 2026-09-01 | 2026-10-20 |
| SBRT Combined With Iparomlimab and Tuvonralimab (QL1706) and Bevacizumab for Hepatocellular Carcinoma Stereotactic Body Radiotherapy, Bevacizumab, Iparomlimab and Tuvonralimab - Hepatocellular Carcinoma (HCC) | Phase 2 | Not yet recruiting | Peking University Cancer Hospital & Institute | 33 | 2026-10-15 | 2026-10-20 |
| Becotatug Vedotin Plus Pucotenlimab for Metastatic Colorectal Cancer Becotatug Vedotin (MRG003), Pucotenlimab - Metastatic Colorectal Cancer | Phase 2 | Recruiting | Fudan University | 31 | 2026-10-15 | 2026-10-20 |
| Iparomlimab and Tuvonralimab With With Cetuximab in Resectable OSCC iparomlimab and tuvonralimab combined with cetuximab - Head and Neck Cancer | Phase 2 | Recruiting | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 26 | 2026-10-16 | 2026-10-20 |
| Becotatug Vedotin + Pucotenlimab+Platinum Induction and Sequential CCRT for Unresectable LA NSCLC Becotatug Vedotin (MRG003)+pucotenlimab+platinum, radiotherapy - Non-Small Cell Carcinoma of Lung, Locally Advanced | Phase 2 | Not yet recruiting | Sun Yat-sen University | 24 | 2026-11-15 | 2026-10-20 |
| Improving Combined PET/CT and MRI of the Breast Using Dedicated Breast Positioning and Image Registration Prone Breast PET/CT Acquisition - Breast Cancer, Breast - Female | Not applicable | Not yet recruiting | Universität Münster | 20 | 2026-10-06 | 2026-10-20 |
| BEX101 in B-cell Non-Hodgkin's Lymphoma BEX101 injection - Non-Hodgkin's Lymphoma | Phase 1 / Phase 2 | Recruiting | Chinese PLA General Hospital | 20 | 2026-10-15 | 2026-10-22 |
| Neoadjuvant Pembrolizumab in Patients With High Risk, Stage IIB/IIC Cutaneous Melanoma: a Single Arm Proof of Concept Phase IIA Study. Pembrolizumab neoadjuvant treatment, surgery, Adjuvant treatment - Stage IIB Melanoma, Stage IIC Melanoma | Phase 2 | Not yet recruiting | Centre Hospitalier Universitaire de Besancon | 19 | 2026-11-01 | 2026-10-20 |
| Acute Effects of Ketone Monoester Co-ingestion With Dietary Protein on Whole-body Phenylalanine Oxidation, Phenylalanine Retention, and Myofibrillar Protein Breakdown Following Resistance Exercise in Young Males. Ketone Monoester + Dietary Protein (KET+PRO), Dietary Protein (PRO), Resistance Exercise - Post-exercise Period, Ketosis | Not applicable | Not yet recruiting | McGill University | 18 | 2026-10-15 | 2026-10-21 |
| Acute Effects of Ketone Monoester Co-Ingestion With Dietary Protein on Whole-Body Phenylalanine Oxidation, Phenylalanine Retention, and Myofibrillar Protein Breakdown Following Resistance Exercise in Older Males Ketone Monoester + Dietary Protein (KET+PRO), Dietary Protein (PRO), Resistance Exercise - Ketosis, Resistance Exercise | Not applicable | Not yet recruiting | McGill University | 18 | 2026-11-01 | 2026-10-20 |
| Phase I Safety Clinical Trial of Anti-CD19 CAR-T Therapy COL01 for the Treatment of Adults With Relapsed or Refractory B-cell Lymphoid Neoplasms: First-in-human Administration, COLIBRI. CAR-T anti-CD19 COL01 - Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia, Lymphoid Malignancies | Phase 1 | Not yet recruiting | GUSTAVO SALGUERO | 12 | 2027-04-01 | 2026-10-20 |
| EMBRACE (EMPA in BReast Cancer for Activity and Cardiac ProtEction) Empagliflozin - Breast Cancer, Supportive Care in Cancer | Phase 2 | Not yet recruiting | Virginia Commonwealth University | 10 | 2026-12-01 | 2026-10-20 |
| Feasibility and Acceptability of Remote Saliva Collection Salivary Cortisol Collection, Blood Biomarker Collection, Hair Cortisol Collection - Survivors of Childhood Cancer, Acute Lymphoblastic Leukemia, Childhood | Recruiting | St. Jude Children's Research Hospital | 100 | 2026-10-01 | 2026-10-20 | |
| Diagnostic Accuracy and Utility of ZTE Added to Routine MRI MRI - Breast Cancer, MRI Imaging | Not yet recruiting | Amal Ahmed Helmy | 100 | 2026-12-01 | 2026-10-20 | |
| Window of Opportunity Study of Lixumistat in Patients With Newly Diagnosed Glioblastoma Lixumistat - Cohort 1, Lixumistat - Cohort 2 - Glioblastoma | Early Phase 1 | Recruiting | Macarena De La Fuente, MD | 10 | 2026-12-01 | 2026-10-20 |
| Maternal and Fetal Outcomes in Pregnancy With Malignancy Pregnancy Disease, Malignancy | Not yet recruiting | Assiut University | 50 | 2026-10-20 | 2026-10-20 | |
| Liver Transplantation for Colorectal Cancer Liver transplantation - Colorectal Cancer, Liver Metastasis | Recruiting | Pontificia Universidad Catolica de Chile | 10 | 2026-06-01 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Psychoactive Drug Use and Acute Care Use After Trauma and Out-of-Hospital Cardiac Arrest Opioids (ATC N02A), Antiepileptics (ATC N03A), Antipsychotics (ATC N05A) - Wounds and Injuries, Out-of-Hospital Cardiac Arrest | Active not recruiting | Azienda Usl di Bologna | 52720 | 2026-06-10 | 2026-10-20 | |
| A Study of LY3873862 in Participants With Sporadic or Familial Amyotrophic Lateral Sclerosis (ALS). LY3873862, CYP450 Drug Cocktail, Placebo - Amyotrophic Lateral Sclerosis, Cytochrome P-450 Enzyme System | Phase 1 | Not yet recruiting | Eli Lilly and Company | 32 | 2026-11-01 | 2026-10-20 |
| Early Administration of Angong Niuhuang Pill for Disabling Acute Ischemic Stroke (EAGER Trial) Angong Niuhuang Pill, Angong Niuhuang Pill Matching Placebo - Acute Ischemic Stroke | Not applicable | Not yet recruiting | Xuanwu Hospital, Beijing | 1200 | 2026-10-01 | 2026-10-20 |
| SmartEnLite for Nursing Home Residents With Dementia Smart Environmental Light (SmartEnLite) - Alzheimer's Disease and Related Dementias, Alzheimer Disease and Related Dementias | Not applicable | Not yet recruiting | Penn State University | 300 | 2026-12-01 | 2026-10-20 |
| EXercise-induced PhysioLogical Adaptations In Neurological Disorders Acute Exercise - Epilepsy, Functional Neurological Disorder | Not applicable | Recruiting | Brigham and Women's Hospital | 240 | 2026-07-22 | 2026-10-20 |
| Comparing Spinal, Epidural, and Dural Puncture Epidural Anesthesia for Cesarean Delivery: Hemodynamics and Block Quality Spinal Anesthesia, Epidural Anesthesia, Dural Puncture Epidural Anesthesia - Hypotension After Neuraxial Anesthesia, Cesarean Section | Not applicable | Not yet recruiting | Bursa Yuksek Ihtisas Training and Research Hospital | 120 | 2026-12-01 | 2026-10-20 |
| Closed Versus Open Endotracheal Suctioning and Ventilator-Associated Pneumonia in Severe Traumatic Brain Injury Closed endotracheal suction system, Open endotracheal suction - Ventilator-associated Pneumonia, Traumatic Brain Injury | Not applicable | Not yet recruiting | Minia University | 120 | 2026-10-04 | 2026-10-20 |
| Utilization of Aerobic Exercise to Maintain Neurologic Health Aerobic Exercise - Parkinson's Disease | Not applicable | Not yet recruiting | The Cleveland Clinic | 100 | 2026-12-15 | 2026-10-20 |
| Haptic-Assisted Virtual Reality Upper-Limb Rehabilitation After Intracerebral Haemorrhage Haptic-assisted virtual reality training (Bimeo PRO), Conventional rehabilitation - Intracerebral Hemorrhage, Hemorrhagic Stroke | Not applicable | Not yet recruiting | University Medical Centre Maribor | 100 | 2026-11-01 | 2026-10-20 |
| Shedding Light on Dementia With Lewy Bodies: a Multimodal 'Bright Light Treatment' to Modulate Brain Functions BLT plus CBT, Sham BLT - Alzheimer Disease, Dementia | Not applicable | Completed | Azienda Usl di Bologna | 80 | 2021-06-16 | 2026-10-20 |
| Ginger-PD: Ginger as a Modifier of Ghrelin Levels and Gut Function in Parkinson's Disease Ginger - REM Sleep Behavior Disorder, Parkinson s Disease | Not applicable | Recruiting | Cambridge University Hospitals NHS Foundation Trust | 72 | 2025-12-17 | 2026-10-21 |
| Virtual Reality Vs Postural Control Training in Children With Cerebral Palsy Virtual reality, Postural control training - Children With Hemiplegic cp | Not applicable | Active not recruiting | Amira Mahmoud Abdelkader Mohamed | 70 | 2026-10-01 | 2026-10-20 |
| Perineural Botulinum Toxin Injection Versus Oral Duloxetine in Relief of Foot Pain in Painful Peripheral Diabetic Neuropathy Botulinum Toxin Type A, Duloxetine, Oral Placebo Tablet - Diabetic Peripheral Neuropathy, Painful Diabetic Neuropathy | Phase 2 | Not yet recruiting | Assiut University | 56 | 2026-11-01 | 2026-10-20 |
| Clinical Significance of Internal Carotid Artery Dolichoarteriopathy Internal Carotid Artery Dolichoarteriopathy, Carotid Artery Tortuosity | Not yet recruiting | Kuban State Medical University | 560 | 2026-10-01 | 2026-10-20 | |
| TPSAlz - Transcranial Pulse Stimulation in Alzheimer's Disease Transcranial pulse stimulation (TPS) - Alzheimer Disease, Mild Cognitive Impairment | Not applicable | Completed | IRCCS San Raffaele Roma | 52 | 2024-05-30 | 2026-10-20 |
| Comparison of the Effectiveness of Motor Imagery Exercises and Suboccipital Myofascial Release Techniques in Nonspecific Chronic Neck Pain Active Exercise, Motor Imagery, Suboccipital Myofascial Release - Non-specific Chronic Neck Pain | Not applicable | Not yet recruiting | Ankara Yildirim Beyazıt University | 51 | 2026-11-01 | 2026-10-20 |
| Impact of Continuous Positive Airway Pressure Therapy on Bilateral Local Hippocampal Gray Matter Volume in Elderly Patients With Obstructive Sleep Apnea - Study BBBSAS Continuous Positive Airway Pressure (CPAP) therapy, Multimodal brain MRI with Gadolinium injection - Hypopnea Syndrome, Apnea, Obstructive Sleep | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Saint Etienne | 50 | 2026-11-01 | 2026-10-20 |
| Outcome Prediction and Recovery After Spontaneous Intracerebral Haemorrhage Intracerebral Hemorrhage, Hemorrhagic Stroke | Not yet recruiting | University Medical Centre Maribor | 300 | 2026-11-01 | 2026-10-20 | |
| Comparing Pre-adaptation of In-stock Mesh Over In-house 3D Patient Specific Model to Reconstruct Unilateral Primary Orbital Fracture With and Without Intraoperative Navigation vs Conventional Intraoperative Free-hand Mesh Bending 3D printed patient specific model, Conventional, Brainlab navigation system - Orbital Fractures, Unilateral | Not applicable | Recruiting | Ain Shams University | 30 | 2025-06-01 | 2026-10-20 |
| Comparative Study Of Combined Recession-Resection And Fenestration of Superior Rectus Muscle for Treatment of Dissociated Vertical Deviation resection of superior rectus muscle - Dissociated Vertical Deviation | Not applicable | Not yet recruiting | Assiut University | 30 | 2026-11-01 | 2026-10-20 |
| Targeted Nutritional Intervention (HMB, Arginine, Glutamine) in Patients With Pancreatic Cancer HMB / L-Arginine / L-Glutamine oral nutritional mixture, Standard Dietary Counseling - PDAC, Pancreas Adenocarcinoma (MSI-H) | Not applicable | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 24 | 2026-12-01 | 2026-10-20 |
| Advanced Multi-omics and -System Approaches to Identify Novel Biomarkers for SMA Spinal Muscular Atrophy (SMA) | Recruiting | Istituto Giannina Gaslini | 200 | 2025-02-05 | 2026-10-20 | |
| Multi-Omics Genetic Investigation Strategies to Enhance the Diagnostic Workflow for Rare Diseases Neurodevelopmental Disorders, Intellectual Disability | Recruiting | Istituto Giannina Gaslini | 200 | 2023-09-04 | 2026-10-20 | |
| Analysis of Electroencephalogram (EEG) Changes in Subacute Stroke Patients Stroke, Electroencephalogram (EEG) | Recruiting | Bundang CHA Hospital | 200 | 2021-04-21 | 2026-10-20 | |
| Motion Capture in Box and Bloks Test Inertial Measurement Unit and Box and Block test - Healthy, Parkinson Disease | Completed | IRCCS San Raffaele Roma | 105 | 2020-01-12 | 2026-10-20 | |
| Effects of Adding Motor Imagery Training to Exercise on Pain, Fibromyalgia Impact, and Kinesiophobia in Women With Fibromyalgia: a Randomized Controlled Trial Motor imagery - Pain Management, Fibromyalgia | Completed | Ufuk University | 100 | 2021-05-01 | 2026-10-20 | |
| Antiseizure Medications and CBC in Children With Epilepsy Epilepsy | Not yet recruiting | Assiut University | 80 | 2026-10-20 | 2026-10-20 | |
| Powered Exoskeleton-Assisted Walking in Persons With Spinal Cord Injury Wearable Powered Exoskeleton - Spinal Cord Injuries (SCI), Muscle Spasticity as a Result of Spinal Cord Injury | Completed | IRCCS San Raffaele Roma | 74 | 2024-09-01 | 2026-10-20 | |
| Remote Digital Assessments for Cognitive Disorders Mild Cognitive Impairment (MCI), Alzheimer Disease (AD) | Not yet recruiting | Centre for Addiction and Mental Health | 60 | 2026-11-01 | 2026-10-20 | |
| Multimodal Characterization of Movement Trajectories in Chronic Inflammatory Demyelinating Polyneuropathy Xsens motion suit - CIDP - Chronic Inflammatory Demyelinating Polyneuropathy | Not yet recruiting | Heinrich-Heine University, Duesseldorf | 50 | 2026-10-01 | 2026-10-20 | |
| Concussion Goody Bag Study Sports Related Concussion | Withdrawn | Ann & Robert H Lurie Children's Hospital of Chicago | 2015-10-01 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Psychoactive Drug Use and Acute Care Use After Trauma and Out-of-Hospital Cardiac Arrest Opioids (ATC N02A), Antiepileptics (ATC N03A), Antipsychotics (ATC N05A) - Wounds and Injuries, Out-of-Hospital Cardiac Arrest | Active not recruiting | Azienda Usl di Bologna | 52720 | 2026-06-10 | 2026-10-20 | |
| The First-in-Human Study of GW906 Injection GW906 injection, Placebo - Hypertension | Phase 1 | Completed | Shenzhen Salubris Pharmaceuticals Co., Ltd. | 40 | 2025-03-29 | 2026-10-20 |
| Epcoritamab as Consolidative Therapy for Waldenstr(SqrRoot)(Delta)m Macroglobulinemia (WM) Treated With a Bruton Tyrosine Kinase Inhibitor (BTKi) epcoritamab - Waldenstrom Macroglobulinemia | Phase 2 | Not yet recruiting | National Heart, Lung, and Blood Institute (NHLBI) | 24 | 2026-10-27 | 2026-10-22 |
| Early Administration of Angong Niuhuang Pill for Disabling Acute Ischemic Stroke (EAGER Trial) Angong Niuhuang Pill, Angong Niuhuang Pill Matching Placebo - Acute Ischemic Stroke | Not applicable | Not yet recruiting | Xuanwu Hospital, Beijing | 1200 | 2026-10-01 | 2026-10-20 |
| Long-term Safety Study Following to JRM-001 Treatment in Pediatric Patients With Congenital Heart Disease Single Ventricle, Hypoplastic Left Heart Syndrome (HLHS) | Recruiting | Metcela Inc. | 40 | 2026-09-01 | 2026-10-20 | |
| Energy Dose and Cardioversion Outcomes in AF Synchronized Electrical Cardioversion With Different Energy Strategies, Conventional Step-Up Energy Cardioversion - Atrial Fibrillation (AF) | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 400 | 2026-11-01 | 2026-10-20 |
| Development and Evaluation of a Disease-oriented Scenario Game to Promote ACP Among Older Adults and Family Caregivers tabletop game, ACP Exercise Book - Heart Failure, Older Adults (65 Years and Older) | Not applicable | Not yet recruiting | Taipei Veterans General Hospital, Taiwan | 164 | 2026-10-15 | 2026-10-20 |
| Comparison of Two Pulse Field Ablation Systems for AF Ablation Pulse Field Ablation - AF - Atrial Fibrillation | Not applicable | Recruiting | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | 120 | 2026-07-10 | 2026-10-20 |
| AI-ECG Detection of Occlusion Myocardial Infarction at Emergency Department Triage (TRIACS) Acute Coronary Syndromes, Chest Pain | Not yet recruiting | University Medical Centre Maribor | 1000 | 2026-10-19 | 2026-10-20 | |
| Haptic-Assisted Virtual Reality Upper-Limb Rehabilitation After Intracerebral Haemorrhage Haptic-assisted virtual reality training (Bimeo PRO), Conventional rehabilitation - Intracerebral Hemorrhage, Hemorrhagic Stroke | Not applicable | Not yet recruiting | University Medical Centre Maribor | 100 | 2026-11-01 | 2026-10-20 |
| Effect of ACTIVE-Care on Cancer-Related Fatigue, Hope, and Psychological Resilience in Adolescents With Acute Lymphoblastic Leukemia ACTIVE-Care Integrated Physical Activity-Based Supportive Care Program - Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Adolescent | Not applicable | Completed | Selcuk University | 70 | 2026-07-01 | 2026-10-20 |
| Clinical Significance of Internal Carotid Artery Dolichoarteriopathy Internal Carotid Artery Dolichoarteriopathy, Carotid Artery Tortuosity | Not yet recruiting | Kuban State Medical University | 560 | 2026-10-01 | 2026-10-20 | |
| Outcome Prediction and Recovery After Spontaneous Intracerebral Haemorrhage Intracerebral Hemorrhage, Hemorrhagic Stroke | Not yet recruiting | University Medical Centre Maribor | 300 | 2026-11-01 | 2026-10-20 | |
| A First-in-Human Study to Evaluate the Safety and Efficacy of Left Ventricular Assist Device Combined With Exosome Therapy for Patients With Heart Failure（RESTORATION） Exosome Preparation, Placebo - Heart Failure | Early Phase 1 | Not yet recruiting | Yining Yang | 24 | 2027-01-15 | 2026-10-20 |
| Validation of Cor-IS Impedance Spectroscopy Against Ultrasound Flow-Mediated Dilation Cor-IS FMD, Ultrasound FMD - Endothelial Dysfunction, Acute Myocardial Infarction (AMI) | Completed | Aristotle University Of Thessaloniki | 208 | 2021-09-01 | 2026-10-20 | |
| Analysis of Electroencephalogram (EEG) Changes in Subacute Stroke Patients Stroke, Electroencephalogram (EEG) | Recruiting | Bundang CHA Hospital | 200 | 2021-04-21 | 2026-10-20 | |
| Prospective Study Protocol for Multiparametric PCCT Assessment of Early Ventricular Outcomes After CABG Coronary Artery Bypass Grafting (CABG) Surgery, Coronary Artery Disease | Recruiting | Xin Lou | 150 | 2025-10-10 | 2026-10-20 | |
| Motion Capture in Box and Bloks Test Inertial Measurement Unit and Box and Block test - Healthy, Parkinson Disease | Completed | IRCCS San Raffaele Roma | 105 | 2020-01-12 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of LY4167586 in Participants With Obesity or Overweight With or Without Type 2 Diabetes LY4167586, Placebo - Obesity, Overweight | Phase 1 | Not yet recruiting | Eli Lilly and Company | 617 | 2026-10-01 | 2026-10-20 |
| A Two-Part, Open-Label, Phase 3 Study Evaluating the Efficacy and Safety of WS016 for the Treatment of Hyperkalemia WS016 - Hyperkalemia | Phase 3 | Recruiting | Waterstone Pharmaceutical (Wuhan) Co., LTD. | 300 | 2026-09-25 | 2026-10-20 |
| Safety and Efficacy of Iron Prophylaxis With on Iron Homeostasis in Healthy Pregnant Women Iron plus folic acid, Folic acid - Iron Deficiency Anemia in Pregnancy, Iron Deficiency in Pregnancy | Not applicable | Recruiting | IBSA Farmaceutici Italia Srl | 162 | 2026-05-18 | 2026-10-20 |
| Effects of a 12-Week Solid Beverage Intervention on Suboptimal Health Status Meta Solid Beverage A, Meta Solid Beverage B - Metabolic Disorder, Sub-health Status | Not applicable | Recruiting | ChinaNorm | 70 | 2026-07-12 | 2026-10-20 |
| A Study of LY3873862 in Participants With Sporadic or Familial Amyotrophic Lateral Sclerosis (ALS). LY3873862, CYP450 Drug Cocktail, Placebo - Amyotrophic Lateral Sclerosis, Cytochrome P-450 Enzyme System | Phase 1 | Not yet recruiting | Eli Lilly and Company | 32 | 2026-11-01 | 2026-10-20 |
| A PHASE 2A, EXPLORATORY, RANDOMIZED, SINGLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY OF WEIGHT LOSS INDUCED BY NKS-3 IN OBESE ADULTS. Investigational product is a modified linoleic acid, named NKS-3. This non-caloric agent, synthetized from linoleic acid, is a fat taste receptors agonist, targeting CD36 with also an impact on GPR120, Placebo solution - Obesity / Overweight, Obesity (BMI Equal to or >30) | Phase 2 | Not yet recruiting | EktaH | 31 | 2026-10-20 | 2026-10-20 |
| Immunonutrition for Surgical Prehabilitation of Patients With Upper GI Cancer Oral nutritional supplements with immunonutrition (enriched with arginine, nucleotides, vitamin D and omega-3-fatty acid), Standart of care - Upper GI Cancer | Not applicable | Enrolling by invitation | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | 110 | 2026-01-01 | 2026-10-20 |
| IGOB131 As A GLP-1 Modulator For Metabolic Disorders In Adults With Obesity IGOB131, Dextrin - Obesity & Overweight | Phase 2 | Not yet recruiting | University of Yaounde 1 | 80 | 2026-12-01 | 2026-10-20 |
| AI-CARE: A Novel AI-Driven Mobile Insulin Calculator Integrating Image- Based Carbohydrate Estimation and CGM AI-CARE, Usual Care Group - Diabetes Mellitus | Not applicable | Not yet recruiting | Tan Tock Seng Hospital | 48 | 2026-10-01 | 2026-10-20 |
| Effects of Yerba Mate Supplementation on Metabolic Health, Physical Function, and Cognition in Older Adults With Excess Adiposity Yerba Mate, Placebo - Overweight (BMI > 25), Obesity & Overweight | Not applicable | Completed | University of North Alabama | 25 | 2025-11-15 | 2026-10-20 |
| Acute Effects of Ketone Monoester Co-ingestion With Dietary Protein on Whole-body Phenylalanine Oxidation, Phenylalanine Retention, and Myofibrillar Protein Breakdown Following Resistance Exercise in Young Males. Ketone Monoester + Dietary Protein (KET+PRO), Dietary Protein (PRO), Resistance Exercise - Post-exercise Period, Ketosis | Not applicable | Not yet recruiting | McGill University | 18 | 2026-10-15 | 2026-10-21 |
| Acute Effects of Ketone Monoester Co-Ingestion With Dietary Protein on Whole-Body Phenylalanine Oxidation, Phenylalanine Retention, and Myofibrillar Protein Breakdown Following Resistance Exercise in Older Males Ketone Monoester + Dietary Protein (KET+PRO), Dietary Protein (PRO), Resistance Exercise - Ketosis, Resistance Exercise | Not applicable | Not yet recruiting | McGill University | 18 | 2026-11-01 | 2026-10-20 |
| Effects of Adding a Registered Dietitian to Rural Community Healthy Behavior Support Services for Management of Type 2 Diabetes Medical Nutrition Therapy Intervention - Type 2 Diabetes | Not applicable | Completed | Indiana University | 14 | 2023-05-16 | 2026-10-20 |
| Milk Beta Caseins on Digestive Discomfort, Gastric Emptying A1/A2 milk with oral naloxone, A1PF milk with oral naloxone - Lactose Intolerants, Lactose Malabsorption | Not applicable | Completed | Purdue University | 10 | 2025-01-30 | 2026-10-20 |
| Tenapanor in Maintenance Hemodialysis Patients Tenapanor - Hyperphosphatemia, Maintenance Hemodialysis | Not yet recruiting | Huashan Hospital | 70 | 2026-09-23 | 2026-10-20 | |
| Native T1 Mapping and ECV in Chronic Hemolytic Anemia Hemolytic Anemia, Thalassemia | Not yet recruiting | Assiut University | 54 | 2026-10-20 | 2026-10-20 | |
| Diagnostic Work-up of Nephrocalcinosis in Children Nephrocalcinosis | Not yet recruiting | Assiut University | 40 | 2026-10-20 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SmartEnLite for Nursing Home Residents With Dementia Smart Environmental Light (SmartEnLite) - Alzheimer's Disease and Related Dementias, Alzheimer Disease and Related Dementias | Not applicable | Not yet recruiting | Penn State University | 300 | 2026-12-01 | 2026-10-20 |
| EXercise-induced PhysioLogical Adaptations In Neurological Disorders Acute Exercise - Epilepsy, Functional Neurological Disorder | Not applicable | Recruiting | Brigham and Women's Hospital | 240 | 2026-07-22 | 2026-10-20 |
| Virtual Reality for Pain and Anxiety During Intravenous Catheterization virtual reality glass - VR, Pain | Not applicable | Completed | Erzincan Binali Yildirim Universitesi | 136 | 2025-03-20 | 2026-10-20 |
| Cognitive Behavioral Therapy for Substance Use and Mental Health in University Students Cognitive-Behavioral Therapy (CBT)-Based Group Intervention, Group Counseling Program - Substance Use Behavior | Not applicable | Completed | Mehmet Akif Ersoy University | 90 | 2026-01-12 | 2026-10-20 |
| Shedding Light on Dementia With Lewy Bodies: a Multimodal 'Bright Light Treatment' to Modulate Brain Functions BLT plus CBT, Sham BLT - Alzheimer Disease, Dementia | Not applicable | Completed | Azienda Usl di Bologna | 80 | 2021-06-16 | 2026-10-20 |
| Ginger-PD: Ginger as a Modifier of Ghrelin Levels and Gut Function in Parkinson's Disease Ginger - REM Sleep Behavior Disorder, Parkinson s Disease | Not applicable | Recruiting | Cambridge University Hospitals NHS Foundation Trust | 72 | 2025-12-17 | 2026-10-21 |
| Applying Comfort Theory to an AI-Assisted Group Music Intervention: Psychosocial and Physiological Outcomes and Feasibility in Long-Term Care Residents. Group music intervention, AI-assisted monitoring system - Comfort Theory, AI-Assisted Group Music Intervention | Not applicable | Not yet recruiting | Yu Chia Chang | 60 | 2026-10-01 | 2026-10-20 |
| Clinical Significance of Internal Carotid Artery Dolichoarteriopathy Internal Carotid Artery Dolichoarteriopathy, Carotid Artery Tortuosity | Not yet recruiting | Kuban State Medical University | 560 | 2026-10-01 | 2026-10-20 | |
| TPSAlz - Transcranial Pulse Stimulation in Alzheimer's Disease Transcranial pulse stimulation (TPS) - Alzheimer Disease, Mild Cognitive Impairment | Not applicable | Completed | IRCCS San Raffaele Roma | 52 | 2024-05-30 | 2026-10-20 |
| Developing Virtual Reality Programs to Address Social Skills Deficits in Youth With ADHD VIP Suite - Attention-Deficit/Hyperactivity Disorder (ADHD) | Not applicable | Not yet recruiting | Indiana University | 48 | 2026-11-01 | 2026-10-20 |
| Individualized Parent-Based Nutrition Education in Preschool Children With Autism Spectrum Disorder Individualized Parent-Based Nutrition Education Programme - Autism Spectrum Disorder | Not applicable | Completed | Firat University | 45 | 2020-12-15 | 2026-10-20 |
| Effects of Tadalafil on Cognition and Cerebral Hemodynamics in Elderly Patients With Mild Cognitive Impairment Tadalafil 5 mg - Mild Cognitive Impairment (MCI) | Phase 2 | Not yet recruiting | Los Angeles Brain Science Project | 44 | 2026-09-01 | 2026-10-20 |
| Multi-Omics Genetic Investigation Strategies to Enhance the Diagnostic Workflow for Rare Diseases Neurodevelopmental Disorders, Intellectual Disability | Recruiting | Istituto Giannina Gaslini | 200 | 2023-09-04 | 2026-10-20 | |
| Expression Intensity Modulates Social Intention Understanding in ASD Children Autism Spectrum Disorder (ASD) | Not yet recruiting | University of Electronic Science and Technology of China | 90 | 2026-10-10 | 2026-10-20 | |
| Remote Digital Assessments for Cognitive Disorders Mild Cognitive Impairment (MCI), Alzheimer Disease (AD) | Not yet recruiting | Centre for Addiction and Mental Health | 60 | 2026-11-01 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Development and Multi-Centre Validation of a Novel Non-Invasive Melanoma Molecular Diagnostic Test Melanoma | Recruiting | Mitra Bio | 2000 | 2026-06-10 | 2026-10-21 | |
| Safety and Systemic Exposure of YCANTH (VP-102) in Subjects With Common Warts (Verruca Vulgaris) (COVE-5) VP-102 - Common Warts, Common Warts (Verruca Vulgaris) | Phase 2 | Not yet recruiting | Verrica Pharmaceuticals Inc. | 30 | 2026-10-01 | 2026-10-20 |
| Role of Artificial Intelligence in Breast Cancer Screening Via Mammography Transpara software - Breast Cancer | Not applicable | Not yet recruiting | Centre Antoine Lacassagne | 1222 | 2027-01-31 | 2026-10-20 |
| Thymalfasin Combined With Chemotherapy and Immunotherapy in TNBC Neoadjuvant Treatment Thymalfasin - Breast Cancer, TNBC - Triple-Negative Breast Cancer | Phase 2 | Not yet recruiting | Fudan University | 572 | 2026-11-08 | 2026-10-20 |
| Surgical Margin Assessment Using Intra-operative High-resolution PET/CT in Patients With Cancers Referred to Surgical Resection, an Exploratory Pilot Study FDG radiotracer - Breast Cancer, Head and Neck Cancers | Not applicable | Active not recruiting | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 250 | 2026-07-20 | 2026-10-20 |
| Comparison of Topical Clascoterone 1% Cream Versus Adapalene 0.1% Cream in the Treatment of Mild-to-Moderate Acne Vulgaris Clascoterone 1% cream, Adapalene 0.1% cream - Acne Vulgaris | Not applicable | Recruiting | Pak Emirates Military Hospital | 130 | 2026-10-08 | 2026-10-22 |
| Podcast-Based Psychosocial Support for Women Newly Diagnosed With Breast Cancer Psychosocial Support Program - Breast Cancer | Not applicable | Not yet recruiting | Mei Man | 80 | 2026-10-15 | 2026-10-20 |
| Effect of ACTIVE-Care on Cancer-Related Fatigue, Hope, and Psychological Resilience in Adolescents With Acute Lymphoblastic Leukemia ACTIVE-Care Integrated Physical Activity-Based Supportive Care Program - Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Adolescent | Not applicable | Completed | Selcuk University | 70 | 2026-07-01 | 2026-10-20 |
| Improving Combined PET/CT and MRI of the Breast Using Dedicated Breast Positioning and Image Registration Prone Breast PET/CT Acquisition - Breast Cancer, Breast - Female | Not applicable | Not yet recruiting | Universität Münster | 20 | 2026-10-06 | 2026-10-20 |
| Neoadjuvant Pembrolizumab in Patients With High Risk, Stage IIB/IIC Cutaneous Melanoma: a Single Arm Proof of Concept Phase IIA Study. Pembrolizumab neoadjuvant treatment, surgery, Adjuvant treatment - Stage IIB Melanoma, Stage IIC Melanoma | Phase 2 | Not yet recruiting | Centre Hospitalier Universitaire de Besancon | 19 | 2026-11-01 | 2026-10-20 |
| Development of a Multidimensional Prediction Model for the Course and Outcome of Early-Onset Juvenile Idiopathic Arthritis (JIA) Juvenile Idiopathic Arthritis (JIA) | Recruiting | Istituto Giannina Gaslini | 130 | 2024-07-30 | 2026-10-20 | |
| EMBRACE (EMPA in BReast Cancer for Activity and Cardiac ProtEction) Empagliflozin - Breast Cancer, Supportive Care in Cancer | Phase 2 | Not yet recruiting | Virginia Commonwealth University | 10 | 2026-12-01 | 2026-10-20 |
| Diagnostic Accuracy and Utility of ZTE Added to Routine MRI MRI - Breast Cancer, MRI Imaging | Not yet recruiting | Amal Ahmed Helmy | 100 | 2026-12-01 | 2026-10-20 | |
| Traditional Chinese Medicine Treatment for Capecitabine-Related Hand-Foot Syndrome Twelve-Ingredient Prepared Sichuan Aconite Hand and Foot Bath, Standard Basic Nursing Interventions - Palmar and Plantar Erythema, Numbness of the Four Limbs | Early Phase 1 | Not yet recruiting | Emeishan Hospital of Traditional Chinese Medicine | 7 | 2026-10-01 | 2026-10-20 |
| Pulmonary Involvement in Children With Systemic JIA Systemic Juvenile Idiopathic Arthritis, Lung Diseases | Not yet recruiting | Assiut University | 30 | 2026-10-20 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of Iron Prophylaxis With on Iron Homeostasis in Healthy Pregnant Women Iron plus folic acid, Folic acid - Iron Deficiency Anemia in Pregnancy, Iron Deficiency in Pregnancy | Not applicable | Recruiting | IBSA Farmaceutici Italia Srl | 162 | 2026-05-18 | 2026-10-20 |
| A Study to Evaluate Treatment Patterns and Investigate Adult Patients With B-cell Lymphoma Lymphoma, B-Cell | Not yet recruiting | AstraZeneca | 532 | 2026-11-30 | 2026-10-20 | |
| Epcoritamab as Consolidative Therapy for Waldenstr(SqrRoot)(Delta)m Macroglobulinemia (WM) Treated With a Bruton Tyrosine Kinase Inhibitor (BTKi) epcoritamab - Waldenstrom Macroglobulinemia | Phase 2 | Not yet recruiting | National Heart, Lung, and Blood Institute (NHLBI) | 24 | 2026-10-27 | 2026-10-22 |
| RPM Signals in Outpatient CAR T Therapy Cytokine Release Syndrome, Immune Effector Cell-Associated Neurotoxicity Syndrome | Not yet recruiting | Current Health | 125 | 2026-12-01 | 2026-10-20 | |
| Effect of ACTIVE-Care on Cancer-Related Fatigue, Hope, and Psychological Resilience in Adolescents With Acute Lymphoblastic Leukemia ACTIVE-Care Integrated Physical Activity-Based Supportive Care Program - Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Adolescent | Not applicable | Completed | Selcuk University | 70 | 2026-07-01 | 2026-10-20 |
| Effect of Aerobic Training Supported by AI-Based Monitoring on Functional Performance in University Students With Anemia Aerobic Treadmill Training, AI-Supported Adaptive Cognitive Training, Standard Care for Anemia - Anemia | Not applicable | Not yet recruiting | Cairo University | 60 | 2026-10-30 | 2026-10-20 |
| Bispecific Antibody-Based Holding/Bridging Therapy Before CAR-T in Aggressive B-Cell Lymphomas Glofitamab, Epcoritamab, Polatuzumab Vedotin - Aggressive B-cell Non-Hodgkin Lymphoma (aNHL), Relapsed or Refractory B-cell Lymphoma | Phase 2 | Recruiting | National Research Center for Hematology, Russia | 40 | 2026-09-01 | 2026-10-20 |
| BEX101 in B-cell Non-Hodgkin's Lymphoma BEX101 injection - Non-Hodgkin's Lymphoma | Phase 1 / Phase 2 | Recruiting | Chinese PLA General Hospital | 20 | 2026-10-15 | 2026-10-22 |
| Phase I Safety Clinical Trial of Anti-CD19 CAR-T Therapy COL01 for the Treatment of Adults With Relapsed or Refractory B-cell Lymphoid Neoplasms: First-in-human Administration, COLIBRI. CAR-T anti-CD19 COL01 - Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia, Lymphoid Malignancies | Phase 1 | Not yet recruiting | GUSTAVO SALGUERO | 12 | 2027-04-01 | 2026-10-20 |
| Neonatal Thrombocytopenia in the NICU Thrombocytopenia, Neonatal Thrombocytopenia | Not yet recruiting | Assiut University | 120 | 2026-10-20 | 2026-10-20 | |
| An Exploratory Study on the Use of Gecacitinib in Patients With Myeloid Malignancies and Myelofibrosis During the Peri-transplant Period Following Allogeneic Hematopoietic Stem Cell Transplantation gecacitinib Hydrochloride Tablets - Myeloid Neoplasms With Myelofibrosis | Phase 1 / Phase 2 | Not yet recruiting | Ruijin Hospital | 10 | 2026-10-15 | 2026-10-20 |
| Feasibility and Acceptability of Remote Saliva Collection Salivary Cortisol Collection, Blood Biomarker Collection, Hair Cortisol Collection - Survivors of Childhood Cancer, Acute Lymphoblastic Leukemia, Childhood | Recruiting | St. Jude Children's Research Hospital | 100 | 2026-10-01 | 2026-10-20 | |
| Anxiety and Depression in Patients With Hematologic Malignancies Baseline Anxiety and/or Depression - Hematologic Disease | Recruiting | The First Affiliated Hospital of Xiamen University | 100 | 2026-10-20 | 2026-10-20 | |
| Native T1 Mapping and ECV in Chronic Hemolytic Anemia Hemolytic Anemia, Thalassemia | Not yet recruiting | Assiut University | 54 | 2026-10-20 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 2/3 Clinical Trial to Evaluate the Immunogenicity and Safety of GC3114B in Adults Aged 65 Years or Older vaccination of GC3114B, Vaccination of Efluelda - Influenza A, Influenza B, Influenza Vaccination | Phase 2 / Phase 3 | Not yet recruiting | GC Biopharma Corp | 1806 | 2026-10-01 | 2026-10-20 |
| A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacterial Sexually Transmitted Infections (STI) in Young African Women Doxycycline hyclate, Standard of Care for STI prevention - Sexually Transmitted Infection (STI), Gonorrhea | Phase 3 | Not yet recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 580 | 2026-11-30 | 2026-10-20 |
| A Study of Updated mRNA Seasonal Influenza Vaccines mRNA-1010, Licensed High-Dose Seasonal Influenza Vaccine - Seasonal Influenza | Phase 4 | Not yet recruiting | ModernaTX, Inc. | 200 | 2026-10-15 | 2026-10-20 |
| Individualized Management of Plaque-Related Gingival Inflammation in Routine Dental Practice Structured Preventive Care Workflow (iMGi) - Plaque-Induced Gingivitis | Not applicable | Not yet recruiting | Curaden AG | 100 | 2026-12-01 | 2026-10-20 |
| Phase 2 Study of SYH2066 Tablets Compared With Placebo in Chinese Adult Patients With Respiratory Syncytial Virus Infection. SYH2066, Placebo - Respiratory Syncytial Virus Infections | Phase 2 | Not yet recruiting | CSPC Ouyi Pharmaceutical Co., Ltd. | 80 | 2026-11-13 | 2026-10-20 |
| Safety and Systemic Exposure of YCANTH (VP-102) in Subjects With Common Warts (Verruca Vulgaris) (COVE-5) VP-102 - Common Warts, Common Warts (Verruca Vulgaris) | Phase 2 | Not yet recruiting | Verrica Pharmaceuticals Inc. | 30 | 2026-10-01 | 2026-10-20 |
| Expanded Diagnostic Strategy in Older Adults Hospitalized With Community-Acquired Acute Respiratory Infection Expanded Diagnostic Strategy, Conventional Diagnostic Strategy - Acute Respiratory Infection | Not applicable | Not yet recruiting | Santiago Lopez Gil | 406 | 2026-10-01 | 2026-10-20 |
| Optimizing Antibiotic Prescription in STI Clinics Using Rapid POCT cobas® Liat® CT/NG Point-of-Care Test - Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection | Not applicable | Not yet recruiting | Hospices Civils de Lyon | 404 | 2026-12-01 | 2026-10-20 |
| Assessment of the Acceptability of, and Factors Associated With, Recommended Vaccinations During Pregnancy in Maternity Units in the Ile-de-France Region Vaccination Coverage Among Pregnant Women | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 1605 | 2026-11-01 | 2026-10-20 | |
| Immunogenicity of Standard-Dose Versus High-Dose Influenza Vaccines in Older Adults in Singapore High-dose influenza vaccine, Standard-dose influenza vaccine - Influenza | Phase 4 | Not yet recruiting | Tan Tock Seng Hospital | 150 | 2026-11-01 | 2026-10-20 |
| Closed Versus Open Endotracheal Suctioning and Ventilator-Associated Pneumonia in Severe Traumatic Brain Injury Closed endotracheal suction system, Open endotracheal suction - Ventilator-associated Pneumonia, Traumatic Brain Injury | Not applicable | Not yet recruiting | Minia University | 120 | 2026-10-04 | 2026-10-20 |
| Alpha-Lipoic Acid as an Adjunct to Non-Surgical Periodontal Treatment in Gingivitis Placebo Administration, Alpha-Lipoic Acid 200 mg, Alpha-Lipoic Acid 600 mg - Gingivitis and Periodontal Diseases | Not applicable | Recruiting | Biruni University | 80 | 2026-08-05 | 2026-10-20 |
| St. John's Wort Oil Versus Chlorhexidine Mouthwash for Gingival Problems After Rapid Maxillary Expansion St. John's Wort Oil, Chlorhexidine - Gingivitis, Maxillary Transversal Deficiency | Not applicable | Completed | Yuzuncu Yil University | 60 | 2019-06-10 | 2026-10-20 |
| Phase I Safety Clinical Trial of Anti-CD19 CAR-T Therapy COL01 for the Treatment of Adults With Relapsed or Refractory B-cell Lymphoid Neoplasms: First-in-human Administration, COLIBRI. CAR-T anti-CD19 COL01 - Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia, Lymphoid Malignancies | Phase 1 | Not yet recruiting | GUSTAVO SALGUERO | 12 | 2027-04-01 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 2/3 Clinical Trial to Evaluate the Immunogenicity and Safety of GC3114B in Adults Aged 65 Years or Older vaccination of GC3114B, Vaccination of Efluelda - Influenza A, Influenza B, Influenza Vaccination | Phase 2 / Phase 3 | Not yet recruiting | GC Biopharma Corp | 1806 | 2026-10-01 | 2026-10-20 |
| A Study of Updated mRNA Seasonal Influenza Vaccines mRNA-1010, Licensed High-Dose Seasonal Influenza Vaccine - Seasonal Influenza | Phase 4 | Not yet recruiting | ModernaTX, Inc. | 200 | 2026-10-15 | 2026-10-20 |
| Expanded Diagnostic Strategy in Older Adults Hospitalized With Community-Acquired Acute Respiratory Infection Expanded Diagnostic Strategy, Conventional Diagnostic Strategy - Acute Respiratory Infection | Not applicable | Not yet recruiting | Santiago Lopez Gil | 406 | 2026-10-01 | 2026-10-20 |
| Union-LC-MPE Cohort:A Multicenter Cohort Study on Diagnosis and Prognosis of Malignant Pleural Effusion in Lung Cance Malignant Pleural Effusions (Mpe), Lung Cancer (Diagnosis) | Not yet recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 3000 | 2026-10-01 | 2026-10-20 | |
| Surgical Margin Assessment Using Intra-operative High-resolution PET/CT in Patients With Cancers Referred to Surgical Resection, an Exploratory Pilot Study FDG radiotracer - Breast Cancer, Head and Neck Cancers | Not applicable | Active not recruiting | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 250 | 2026-07-20 | 2026-10-20 |
| Assessment of the Acceptability of, and Factors Associated With, Recommended Vaccinations During Pregnancy in Maternity Units in the Ile-de-France Region Vaccination Coverage Among Pregnant Women | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 1605 | 2026-11-01 | 2026-10-20 | |
| Immunogenicity of Standard-Dose Versus High-Dose Influenza Vaccines in Older Adults in Singapore High-dose influenza vaccine, Standard-dose influenza vaccine - Influenza | Phase 4 | Not yet recruiting | Tan Tock Seng Hospital | 150 | 2026-11-01 | 2026-10-20 |
| Closed Versus Open Endotracheal Suctioning and Ventilator-Associated Pneumonia in Severe Traumatic Brain Injury Closed endotracheal suction system, Open endotracheal suction - Ventilator-associated Pneumonia, Traumatic Brain Injury | Not applicable | Not yet recruiting | Minia University | 120 | 2026-10-04 | 2026-10-20 |
| Diagnostic Performance of an AI-Based Multi-Omics Model for Early Lung Cancer Pulmonary Nodules, Early Detection of Cancer | Not yet recruiting | Beijing Chao Yang Hospital | 1050 | 2026-10-21 | 2026-10-20 | |
| Temporal Dynamics of Peripheral SpO₂ During Reoxygenation Voluntary Apnea - Healthy Vollunteer, Apnea | Not applicable | Recruiting | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 100 | 2026-08-03 | 2026-10-20 |
| Impact of Continuous Positive Airway Pressure Therapy on Bilateral Local Hippocampal Gray Matter Volume in Elderly Patients With Obstructive Sleep Apnea - Study BBBSAS Continuous Positive Airway Pressure (CPAP) therapy, Multimodal brain MRI with Gadolinium injection - Hypopnea Syndrome, Apnea, Obstructive Sleep | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Saint Etienne | 50 | 2026-11-01 | 2026-10-20 |
| A Behavioral Circuit Breathing Training Intervention on Smoking Cessation and Respiratory Function Among Youth Who Use E-cigarettes Circuit Breathing Intervention, Diaphragmatic Breathing - E Cigarette Use | Not applicable | Recruiting | Chulalongkorn University | 45 | 2026-09-01 | 2026-10-20 |
| Becotatug Vedotin + Pucotenlimab+Platinum Induction and Sequential CCRT for Unresectable LA NSCLC Becotatug Vedotin (MRG003)+pucotenlimab+platinum, radiotherapy - Non-Small Cell Carcinoma of Lung, Locally Advanced | Phase 2 | Not yet recruiting | Sun Yat-sen University | 24 | 2026-11-15 | 2026-10-20 |
| Pulmonary Involvement in Children With Systemic JIA Systemic Juvenile Idiopathic Arthritis, Lung Diseases | Not yet recruiting | Assiut University | 30 | 2026-10-20 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacterial Sexually Transmitted Infections (STI) in Young African Women Doxycycline hyclate, Standard of Care for STI prevention - Sexually Transmitted Infection (STI), Gonorrhea | Phase 3 | Not yet recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 580 | 2026-11-30 | 2026-10-20 |
| Optimizing Antibiotic Prescription in STI Clinics Using Rapid POCT cobas® Liat® CT/NG Point-of-Care Test - Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection | Not applicable | Not yet recruiting | Hospices Civils de Lyon | 404 | 2026-12-01 | 2026-10-20 |
| Efficacy of a Video-based, Parent-centered Home Developmental Intervention for Infants at High Risk for Developmental Delay: a Multicenter Randomized Controlled Trial Family-centered developmental training intervention - Preterm | Not applicable | Not yet recruiting | Seoul National University Hospital | 170 | 2026-12-01 | 2026-10-20 |
| AI Analysis of CT Scans to Classify Ovarian Tumours as Benign, Borderline or Malignant Before Surgery Ovarian Cancer, Ovarian Tumor | Not yet recruiting | Catharina Ziekenhuis Eindhoven | 1300 | 2026-11-01 | 2026-10-20 | |
| Oral Multi-Strain Lactobacillus Probiotic for Women With Vaginal Dysbiosis Low-dose multi-strain Lactobacillus capsule, High-dose capsule, Placebo capsule - Vaginitis, Dysbiosis | Not applicable | Completed | Soon Chun Hyang University | 119 | 2023-05-28 | 2026-10-20 |
| HRT-PC Trial: Hormone Recovery After Treatment for Prostate Cancer Trial. An Open-label Phase II Study of Clomiphene Citrate in Patients With Persistent Hypogonadism After ADT for Treatment of Localized Prostate Cancer Clomiphene Citrate 25mg - Prostate Cancer | Phase 2 | Not yet recruiting | University of Nebraska | 83 | 2027-01-31 | 2026-10-20 |
| Effects of Web-Based Ovarian Cancer Awareness Education on Women's Health Beliefs and Risk-Reducing Behaviors Web-Based Ovarian Cancer Awareness Education, General Reproductive Health Information - Ovarian Cancer | Not applicable | Not yet recruiting | Ege University | 82 | 2026-11-01 | 2026-10-22 |
| 27-Inch Versus 55-Inch Monitors in Women Undergoing Endometrial Cancer Surgery 27-Inch Endoscopic Imaging Monitor, 55-Inch Endoscopic Imaging Monitor - Endometrial Cancer | Not applicable | Not yet recruiting | Metehan Uzundal | 70 | 2026-10-01 | 2026-10-20 |
| Parent-Facilitated Early Oral-Sensory Experience in the NICU for Feeding Outcomes Parent-Facilitated Early Oral-Sensory Experience (PEOE) - Premature Birth, Infant, Premature | Not applicable | Not yet recruiting | Boston College | 60 | 2026-11-01 | 2026-10-20 |
| Transcutaneous Genital Nerves Stimulation for the Treatment of Refractory Chronic Pelvic and Genital Pain in Women. Transcutaneous Genital Nerves Stimulation - Refractory Visceral Pelvic Pain, Refractory Genital Pain | Not applicable | Not yet recruiting | Prof. Dr. med. Marc Possover | 50 | 2026-12-01 | 2026-10-20 |
| Radiotherapy for Gynecologic Cancer With Up to 10 Active Metastatic Lesions Routine-care metastasis-directed radiotherapy - Cervical Cancer, Gynecologic Cancer | Recruiting | Affidea Nu-med Center of Oncological DIagnostics and Therapy | 500 | 2026-10-06 | 2026-10-20 | |
| Platelet Rich Plasma Versus Mitomycin C Injection Following Visual Internal Urethrotomy in Urethral Stricture Visual internal urethrotomy followed by submucosal intralesional mitomycin C injection, Visual internal urethrotomy followed by submucosal Platlet Rich Plasma injection - Urethral Stricture | Phase 3 | Completed | Ain Shams University | 50 | 2025-08-01 | 2026-10-20 |
| Postoperative Pain Trajectories After Endometriosis Surgery Perioperative quantitative sensory testing, questionnaire - Endometriosis, Postoperative Pain | Recruiting | Centre Hospitalier Universitaire, Amiens | 150 | 2026-07-07 | 2026-10-20 | |
| Diagnostic Work-up of Nephrocalcinosis in Children Nephrocalcinosis | Not yet recruiting | Assiut University | 40 | 2026-10-20 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Post-Market Clinical Follow-up of Intra-Articular Hyaluronic Acid in Hip Osteoarthritis Hip OA | Recruiting | Meiji Pharma Spain S.A. | 40 | 2026-01-29 | 2026-10-20 | |
| Ultrasound-Guided Injections for Plantar Heel Pain Ultrasound-Guided Baxter Nerve Injection, Ultrasound-Guided Flexor Digitorum Brevis Origin Injection, Combined Ultrasound-Guided Baxter Nerve and Flexor Digitorum Brevis Injections - Plantar Heel Pain, Plantar Fasciosis, Calcaneal Spur | Not applicable | Completed | Kutahya Health Sciences University | 210 | 2023-12-15 | 2026-10-20 |
| Comparative Effectiveness of Ultrasound-Guided Tenoxicam and Corticosteroid Injections for Lateral Epicondylitis methylprednisolone acetate, tenoxicam - Lateral Epicondylitis | Not applicable | Not yet recruiting | Ankara Etlik City Hospital | 72 | 2026-10-01 | 2026-10-20 |
| Aquatic Exercise in Patients With Knee Osteoarthritis Standard physical therapy, Hydrotherapy - Central Sensitization, Knee Osteoarthristis | Not applicable | Recruiting | Kirsehir Ahi Evran Universitesi | 60 | 2026-06-01 | 2026-10-20 |
| Plyometric vs. Intrinsic Foot Muscle Training in Pediatric Flatfoot Plyometric Training - Flatfoot, Flexible | Not applicable | Completed | Faculty of Medicine, Sousse | 36 | 2025-11-15 | 2026-10-20 |
| Comparison of Bracing and Eccentric Loading Exercises on Pain Modulation and Functional Improvement in Acute Pes Anserine Bursitis Patients Medial-Support Knee Brace, Eccentric Loading Exercise - Pes Anserine Bursitis | Not applicable | Completed | Dr Aneeqa Sultan | 32 | 2025-10-20 | 2026-10-20 |
| Preoperative Multimorbidity and Functional Recovery After Total Knee Arthroplasty Knee Osteoarthritis, Multimorbidity | Recruiting | Balikesir Ataturk City Hospital | 230 | 2026-06-26 | 2026-10-20 | |
| Development of a Multidimensional Prediction Model for the Course and Outcome of Early-Onset Juvenile Idiopathic Arthritis (JIA) Juvenile Idiopathic Arthritis (JIA) | Recruiting | Istituto Giannina Gaslini | 130 | 2024-07-30 | 2026-10-20 | |
| Cartilage Biomarker Response to Acute Mechanical Loading in Women With Knee Osteoarthritis: Comparison by Antiresorptive Treatment Status Knee Osteoarthritis | Recruiting | Sisli Hamidiye Etfal Training and Research Hospital | 105 | 2026-05-08 | 2026-10-20 | |
| Effects of Adding Motor Imagery Training to Exercise on Pain, Fibromyalgia Impact, and Kinesiophobia in Women With Fibromyalgia: a Randomized Controlled Trial Motor imagery - Pain Management, Fibromyalgia | Completed | Ufuk University | 100 | 2021-05-01 | 2026-10-20 | |
| The Effectiveness of Extracorporeal Shock Wave Therapy for Elbow Osteochondritis Dissecans (OCD) Extracorporeal Shock Wave Therapy, Extracorporeal Shock Wave Therapy(no-energy) - Elbow Osteochondritis Dissecans | Not applicable | Completed | Chang Gung Memorial Hospital | 9 | 2020-02-12 | 2026-10-21 |
| Powered Exoskeleton-Assisted Walking in Persons With Spinal Cord Injury Wearable Powered Exoskeleton - Spinal Cord Injuries (SCI), Muscle Spasticity as a Result of Spinal Cord Injury | Completed | IRCCS San Raffaele Roma | 74 | 2024-09-01 | 2026-10-20 | |
| Pulmonary Involvement in Children With Systemic JIA Systemic Juvenile Idiopathic Arthritis, Lung Diseases | Not yet recruiting | Assiut University | 30 | 2026-10-20 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate Treatment Patterns and Investigate Adult Patients With B-cell Lymphoma Lymphoma, B-Cell | Not yet recruiting | AstraZeneca | 532 | 2026-11-30 | 2026-10-20 | |
| Epcoritamab as Consolidative Therapy for Waldenstr(SqrRoot)(Delta)m Macroglobulinemia (WM) Treated With a Bruton Tyrosine Kinase Inhibitor (BTKi) epcoritamab - Waldenstrom Macroglobulinemia | Phase 2 | Not yet recruiting | National Heart, Lung, and Blood Institute (NHLBI) | 24 | 2026-10-27 | 2026-10-22 |
| RPM Signals in Outpatient CAR T Therapy Cytokine Release Syndrome, Immune Effector Cell-Associated Neurotoxicity Syndrome | Not yet recruiting | Current Health | 125 | 2026-12-01 | 2026-10-20 | |
| Prophylactic Treatment of Graves Ophthalmopathy (GO) in Newly Diagnosed Graves' Disease (GD) With Atorvastatin (ATORGO) Atorvastatin - Graves Disease, Graves Disease (Basedow's Disease) | Phase 2 | Not yet recruiting | Region Skane | 554 | 2026-11-01 | 2026-10-20 |
| Effect of ACTIVE-Care on Cancer-Related Fatigue, Hope, and Psychological Resilience in Adolescents With Acute Lymphoblastic Leukemia ACTIVE-Care Integrated Physical Activity-Based Supportive Care Program - Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Adolescent | Not applicable | Completed | Selcuk University | 70 | 2026-07-01 | 2026-10-20 |
| Bispecific Antibody-Based Holding/Bridging Therapy Before CAR-T in Aggressive B-Cell Lymphomas Glofitamab, Epcoritamab, Polatuzumab Vedotin - Aggressive B-cell Non-Hodgkin Lymphoma (aNHL), Relapsed or Refractory B-cell Lymphoma | Phase 2 | Recruiting | National Research Center for Hematology, Russia | 40 | 2026-09-01 | 2026-10-20 |
| BEX101 in B-cell Non-Hodgkin's Lymphoma BEX101 injection - Non-Hodgkin's Lymphoma | Phase 1 / Phase 2 | Recruiting | Chinese PLA General Hospital | 20 | 2026-10-15 | 2026-10-22 |
| Development of a Multidimensional Prediction Model for the Course and Outcome of Early-Onset Juvenile Idiopathic Arthritis (JIA) Juvenile Idiopathic Arthritis (JIA) | Recruiting | Istituto Giannina Gaslini | 130 | 2024-07-30 | 2026-10-20 | |
| Phase I Safety Clinical Trial of Anti-CD19 CAR-T Therapy COL01 for the Treatment of Adults With Relapsed or Refractory B-cell Lymphoid Neoplasms: First-in-human Administration, COLIBRI. CAR-T anti-CD19 COL01 - Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia, Lymphoid Malignancies | Phase 1 | Not yet recruiting | GUSTAVO SALGUERO | 12 | 2027-04-01 | 2026-10-20 |
| Feasibility and Acceptability of Remote Saliva Collection Salivary Cortisol Collection, Blood Biomarker Collection, Hair Cortisol Collection - Survivors of Childhood Cancer, Acute Lymphoblastic Leukemia, Childhood | Recruiting | St. Jude Children's Research Hospital | 100 | 2026-10-01 | 2026-10-20 | |
| Multimodal Characterization of Movement Trajectories in Chronic Inflammatory Demyelinating Polyneuropathy Xsens motion suit - CIDP - Chronic Inflammatory Demyelinating Polyneuropathy | Not yet recruiting | Heinrich-Heine University, Duesseldorf | 50 | 2026-10-01 | 2026-10-20 | |
| Pulmonary Involvement in Children With Systemic JIA Systemic Juvenile Idiopathic Arthritis, Lung Diseases | Not yet recruiting | Assiut University | 30 | 2026-10-20 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| GRACE-DE: Prospective Multicenter Real-world Gastric Cancer Patients Starting AZ-developed and Approved Drugs in Germany (Umbrella Study) Gastric Cancer, Gastroesophageal Junction Cancer | Not yet recruiting | AstraZeneca | 300 | 2026-10-31 | 2026-10-20 | |
| SIMBA in Irritable Bowel Syndrome (IBS) Rifaximin (drug), fluid biopsy capsule - Irritable Bowel Syndrome (IBS), Microbiome | Phase 1 | Not yet recruiting | University of Calgary | 180 | 2026-11-01 | 2026-10-20 |
| Impact of Ultra-Processed Food Reduction on Remission Duration in Pediatric Crohn's Disease Ultra-Processed Food Reduction Counseling, Standard Dietary Counseling - Crohn Disease (CD) | Not applicable | Recruiting | University Hospital, Motol | 124 | 2026-08-01 | 2026-10-20 |
| Immunonutrition for Surgical Prehabilitation of Patients With Upper GI Cancer Oral nutritional supplements with immunonutrition (enriched with arginine, nucleotides, vitamin D and omega-3-fatty acid), Standart of care - Upper GI Cancer | Not applicable | Enrolling by invitation | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | 110 | 2026-01-01 | 2026-10-20 |
| Biomarker Investigation for Early Gastric Cancer Detection Saliva sampling, Gastric juice sampling, Blood sampling - Gastro Oesophageal Cancer | Not applicable | Not yet recruiting | Centre Leon Berard | 100 | 2026-11-01 | 2026-10-20 |
| Effect of ACTIVE-Care on Cancer-Related Fatigue, Hope, and Psychological Resilience in Adolescents With Acute Lymphoblastic Leukemia ACTIVE-Care Integrated Physical Activity-Based Supportive Care Program - Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Adolescent | Not applicable | Completed | Selcuk University | 70 | 2026-07-01 | 2026-10-20 |
| Microencapsulated Sodium Propionate in IBD Microbiota Modulation Microencapsulated sodium propiolate, Microencapsulated sodium Butyrate - Crohn Disease | Not applicable | Recruiting | University of Padova | 50 | 2026-10-01 | 2026-10-20 |
| SBRT Combined With Iparomlimab and Tuvonralimab (QL1706) and Bevacizumab for Hepatocellular Carcinoma Stereotactic Body Radiotherapy, Bevacizumab, Iparomlimab and Tuvonralimab - Hepatocellular Carcinoma (HCC) | Phase 2 | Not yet recruiting | Peking University Cancer Hospital & Institute | 33 | 2026-10-15 | 2026-10-20 |
| Becotatug Vedotin Plus Pucotenlimab for Metastatic Colorectal Cancer Becotatug Vedotin (MRG003), Pucotenlimab - Metastatic Colorectal Cancer | Phase 2 | Recruiting | Fudan University | 31 | 2026-10-15 | 2026-10-20 |
| Milk Beta Caseins on Digestive Discomfort, Gastric Emptying A1/A2 milk with oral naloxone, A1PF milk with oral naloxone - Lactose Intolerants, Lactose Malabsorption | Not applicable | Completed | Purdue University | 10 | 2025-01-30 | 2026-10-20 |
| Liver Transplantation for Colorectal Cancer Liver transplantation - Colorectal Cancer, Liver Metastasis | Recruiting | Pontificia Universidad Catolica de Chile | 10 | 2026-06-01 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| STUDY OF THE EFFECTS OF L. CASEI DG® (ENTEROLACTIS BABY) IN HEALTHY PRETERM AND FULL-TERM INFANTS. Enterolactis Baby® drops, Placebo - Gut Microbiota Modulation | Not applicable | Completed | Alfasigma S.p.A. | 61 | 2018-11-02 | 2026-10-20 |
| Prophylactic Treatment of Graves Ophthalmopathy (GO) in Newly Diagnosed Graves' Disease (GD) With Atorvastatin (ATORGO) Atorvastatin - Graves Disease, Graves Disease (Basedow's Disease) | Phase 2 | Not yet recruiting | Region Skane | 554 | 2026-11-01 | 2026-10-20 |
| Long-term Safety Study Following to JRM-001 Treatment in Pediatric Patients With Congenital Heart Disease Single Ventricle, Hypoplastic Left Heart Syndrome (HLHS) | Recruiting | Metcela Inc. | 40 | 2026-09-01 | 2026-10-20 | |
| The Effect of Bitewing Radiography on Outcomes and Costs of Treating Caries in Permanent Teeth Visual-tactile caries examination, Visual-tactile caries examination and bilateral bitewing radiography - Dental Caries, Teeth Loss | Not applicable | Not yet recruiting | Jukka Leinonen | 250 | 2027-03-01 | 2026-10-20 |
| Plyometric vs. Intrinsic Foot Muscle Training in Pediatric Flatfoot Plyometric Training - Flatfoot, Flexible | Not applicable | Completed | Faculty of Medicine, Sousse | 36 | 2025-11-15 | 2026-10-20 |
| Multi-Omics Genetic Investigation Strategies to Enhance the Diagnostic Workflow for Rare Diseases Neurodevelopmental Disorders, Intellectual Disability | Recruiting | Istituto Giannina Gaslini | 200 | 2023-09-04 | 2026-10-20 | |
| Acute Effects of Ketone Monoester Co-ingestion With Dietary Protein on Whole-body Phenylalanine Oxidation, Phenylalanine Retention, and Myofibrillar Protein Breakdown Following Resistance Exercise in Young Males. Ketone Monoester + Dietary Protein (KET+PRO), Dietary Protein (PRO), Resistance Exercise - Post-exercise Period, Ketosis | Not applicable | Not yet recruiting | McGill University | 18 | 2026-10-15 | 2026-10-21 |
| Acute Effects of Ketone Monoester Co-Ingestion With Dietary Protein on Whole-Body Phenylalanine Oxidation, Phenylalanine Retention, and Myofibrillar Protein Breakdown Following Resistance Exercise in Older Males Ketone Monoester + Dietary Protein (KET+PRO), Dietary Protein (PRO), Resistance Exercise - Ketosis, Resistance Exercise | Not applicable | Not yet recruiting | McGill University | 18 | 2026-11-01 | 2026-10-20 |
| Neonatal Thrombocytopenia in the NICU Thrombocytopenia, Neonatal Thrombocytopenia | Not yet recruiting | Assiut University | 120 | 2026-10-20 | 2026-10-20 | |
| Milk Beta Caseins on Digestive Discomfort, Gastric Emptying A1/A2 milk with oral naloxone, A1PF milk with oral naloxone - Lactose Intolerants, Lactose Malabsorption | Not applicable | Completed | Purdue University | 10 | 2025-01-30 | 2026-10-20 |
| Native T1 Mapping and ECV in Chronic Hemolytic Anemia Hemolytic Anemia, Thalassemia | Not yet recruiting | Assiut University | 54 | 2026-10-20 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Individualized Management of Plaque-Related Gingival Inflammation in Routine Dental Practice Structured Preventive Care Workflow (iMGi) - Plaque-Induced Gingivitis | Not applicable | Not yet recruiting | Curaden AG | 100 | 2026-12-01 | 2026-10-20 |
| The Effect of Bitewing Radiography on Outcomes and Costs of Treating Caries in Permanent Teeth Visual-tactile caries examination, Visual-tactile caries examination and bilateral bitewing radiography - Dental Caries, Teeth Loss | Not applicable | Not yet recruiting | Jukka Leinonen | 250 | 2027-03-01 | 2026-10-20 |
| Post-operative Pain and Apical Healing After Root Canal (re)Treatment With Laser-activated Irrigation Versus Sonic or no Activation sonically activated irrigation, laser activated irrigation, conventional needle irrigation - Apical Periodontitis, Post Operative Pain, Acute | Not applicable | Not yet recruiting | University Ghent | 183 | 2026-10-01 | 2026-10-20 |
| This Feasibility Study Will Evaluate the Study Protocols for Treatment and Follow-up Controls of Primary Molars With Caries in Children Treated With Stainless Steel Crowns or Conventional Fillings. Treatment Success and Potential Failures Will be Followed at 3, 6 and 12 Months Post Treatment. Stainless steel crowns, Conventional fillings - Dental Caries, Early Childhood Caries (ECC) | Not applicable | Not yet recruiting | Marie Norman | 100 | 2026-10-05 | 2026-10-20 |
| Alpha-Lipoic Acid as an Adjunct to Non-Surgical Periodontal Treatment in Gingivitis Placebo Administration, Alpha-Lipoic Acid 200 mg, Alpha-Lipoic Acid 600 mg - Gingivitis and Periodontal Diseases | Not applicable | Recruiting | Biruni University | 80 | 2026-08-05 | 2026-10-20 |
| St. John's Wort Oil Versus Chlorhexidine Mouthwash for Gingival Problems After Rapid Maxillary Expansion St. John's Wort Oil, Chlorhexidine - Gingivitis, Maxillary Transversal Deficiency | Not applicable | Completed | Yuzuncu Yil University | 60 | 2019-06-10 | 2026-10-20 |
| Bioceramic Repair Materials in Apexogenesis of Immature Permanent Molars Bioceramic Repair Pulpotomy (BIO-C® REPAIR), Mineral Trioxide Aggregate Pulpotomy (Biofactor MTA) - Apexogenesis, Pulp Exposure, Dental | Not applicable | Completed | Tanta University | 30 | 2024-05-03 | 2026-10-20 |
| Buccal Periosteal Inversion Flap vs Buccal Advancement Flap for Acute Oro-Antral Communication Closure Buccal Periosteal Inversion Flap, Buccal Advancement Flap - Acute Oroantral Communication | Not applicable | Not yet recruiting | Medical University of Graz | 22 | 2026-10-01 | 2026-10-20 |
| Dental Anxiety in Children Attending Emergency Versus Routine Dental Care Dental Anxiety, Dental Fear | Completed | Marmara University | 47 | 2025-03-15 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Psychoactive Drug Use and Acute Care Use After Trauma and Out-of-Hospital Cardiac Arrest Opioids (ATC N02A), Antiepileptics (ATC N03A), Antipsychotics (ATC N05A) - Wounds and Injuries, Out-of-Hospital Cardiac Arrest | Active not recruiting | Azienda Usl di Bologna | 52720 | 2026-06-10 | 2026-10-20 | |
| EXercise-induced PhysioLogical Adaptations In Neurological Disorders Acute Exercise - Epilepsy, Functional Neurological Disorder | Not applicable | Recruiting | Brigham and Women's Hospital | 240 | 2026-07-22 | 2026-10-20 |
| Closed Versus Open Endotracheal Suctioning and Ventilator-Associated Pneumonia in Severe Traumatic Brain Injury Closed endotracheal suction system, Open endotracheal suction - Ventilator-associated Pneumonia, Traumatic Brain Injury | Not applicable | Not yet recruiting | Minia University | 120 | 2026-10-04 | 2026-10-20 |
| Impact of Range of Motion Exercises on Pain and Functional Ability Range of Motion exercises - Impact of ROM Exercises on Pain and Functional Ability in Patients With Second -Degree Burns | Not applicable | Not yet recruiting | Al-Azhar University | 80 | 2026-11-01 | 2026-10-20 |
| Prehospital Transfusion Outcomes in Traumatic Hemorrhage: a Prospective Cohort Study Trauma Associated Hemorrhage | Not yet recruiting | Erasmus Medical Center | 750 | 2026-10-01 | 2026-10-20 | |
| Comparative Effectiveness of Ultrasound-Guided Tenoxicam and Corticosteroid Injections for Lateral Epicondylitis methylprednisolone acetate, tenoxicam - Lateral Epicondylitis | Not applicable | Not yet recruiting | Ankara Etlik City Hospital | 72 | 2026-10-01 | 2026-10-20 |
| Comparing Pre-adaptation of In-stock Mesh Over In-house 3D Patient Specific Model to Reconstruct Unilateral Primary Orbital Fracture With and Without Intraoperative Navigation vs Conventional Intraoperative Free-hand Mesh Bending 3D printed patient specific model, Conventional, Brainlab navigation system - Orbital Fractures, Unilateral | Not applicable | Recruiting | Ain Shams University | 30 | 2025-06-01 | 2026-10-20 |
| Powered Exoskeleton-Assisted Walking in Persons With Spinal Cord Injury Wearable Powered Exoskeleton - Spinal Cord Injuries (SCI), Muscle Spasticity as a Result of Spinal Cord Injury | Completed | IRCCS San Raffaele Roma | 74 | 2024-09-01 | 2026-10-20 | |
| Concussion Goody Bag Study Sports Related Concussion | Withdrawn | Ann & Robert H Lurie Children's Hospital of Chicago | 2015-10-01 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prophylactic Treatment of Graves Ophthalmopathy (GO) in Newly Diagnosed Graves' Disease (GD) With Atorvastatin (ATORGO) Atorvastatin - Graves Disease, Graves Disease (Basedow's Disease) | Phase 2 | Not yet recruiting | Region Skane | 554 | 2026-11-01 | 2026-10-20 |
| Comparative Study Of Combined Recession-Resection And Fenestration of Superior Rectus Muscle for Treatment of Dissociated Vertical Deviation resection of superior rectus muscle - Dissociated Vertical Deviation | Not applicable | Not yet recruiting | Assiut University | 30 | 2026-11-01 | 2026-10-20 |
| Efficacy and Safety of Minimally Invasive Suprachoroidal Drainage Neovascular Glaucoma | Completed | Zhongnan Hospital | 50 | 2024-07-01 | 2026-10-20 |
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing AI and Standard Pregnancy Chatbots Scripted maternal health chatbot, MATRI retrieval-augmented maternal health chatbot - Pregnancy, Prenatal Care | Not applicable | Not yet recruiting | Nivi, Inc. | 2500 | 2026-10-30 | 2026-10-20 |
| A Study of RO7821657 in Participants With Solid Tumors RO7821657 - Locally Advanced or Metastatic Solid Tumors | Phase 1 | Not yet recruiting | Hoffmann-La Roche | 405 | 2026-10-26 | 2026-10-20 |
| RBD1119 in Coronary Artery Disease (CAD) RBD1119, Placebo - Stable Coronary Artery Disease | Phase 2 | Not yet recruiting | Ribocure Pharmaceuticals AB | 200 | 2026-10-16 | 2026-10-20 |
| Metabolic Impact of VLCPUFA-Rich Fish Oil: A Clinical Study on Omega-3 Index Enhancement in Healthy Individuals VLCPUFA-rich fish oil, DHA-rich fish oil - Fatty Acids, Omega-3, Fish Oils | Not applicable | Recruiting | National Heart, Lung, and Blood Institute (NHLBI) | 200 | 2026-10-27 | 2026-10-22 |
| A Study to Evaluate the Efficacy and Safety of AK139 in Patients With Prurigo Nodularis. AK139, Placebo - Prurigo Nodularis (PN) | Phase 2 | Not yet recruiting | Akeso | 132 | 2026-10-01 | 2026-10-20 |
| A Clinical Study to Evaluate the Effects of a Supplement on Cognitive Function Necternal Supplement, Placebo - Cognition Improvement, Cognition Function | Not applicable | Active not recruiting | Necternal LLC | 128 | 2026-08-01 | 2026-10-20 |
| Microneedle-based ISF Sampling Technique PELSA System - No Condition, Healthy Individuals | Not applicable | Not yet recruiting | Ascilion AB | 110 | 2026-11-01 | 2026-10-21 |
| Milk Free From A1-Type β-Casein With Human Milk Oligosaccharides on Gut Health, Immunity, Cognitive Development, and Temperament in Toddlers a2 toddler milk with HMOs, Conventional toddler milk with HMOs - Healthy Volunteers | Not applicable | Not yet recruiting | a2 Milk Company Ltd. | 80 | 2026-11-01 | 2026-10-20 |
| Evaluation of MD60002 Device for Facial Skin Aging Device: MD60002 - Facial Wrinkles, Skin Aging | Not applicable | Not yet recruiting | Promoitalia Group Spa | 43 | 2026-11-20 | 2026-10-20 |
| A Single Ascending Dose Study of DTI-117 Given Intramuscularly in Healthy Participants. DTI-117, Placebo - Healthy Adult | Phase 1 | Not yet recruiting | Dignify Therapeutics | 40 | 2026-10-01 | 2026-10-22 |
| Stigma Healing Inventory Evaluation Pediatric Stigma Education, Pediatric Stigma Standard Education and Adapted Stigma Intervention - Stigma | Not applicable | Not yet recruiting | St. Jude Children's Research Hospital | 2980 | 2026-11-01 | 2026-10-20 |
| A Study to Assess Nicotine Uptake From a Menthol Electronic Nicotine Delivery System Product Menthol 5%, Combustible cigarette - Smoking Behaviors, Smoking ( Cigarette) | Not applicable | Not yet recruiting | RAI Services Company | 28 | 2026-11-15 | 2026-10-20 |
| A Descriptive Analysis of the Physiological and Behavioral Profiles of Elite Female Athletes Female Athletes, Healthy Women | Enrolling by invitation | PepsiCo Global R&D | 50 | 2026-10-01 | 2026-10-20 | |
| Acceptance-based Self-care Intervention for Older Adults With Multimorbidity Acceptance-based activities, Self-care activities - Older Adults (60 - 85 Years Old), Self-care | Not applicable | Not yet recruiting | Chinese University of Hong Kong | 306 | 2027-01-01 | 2026-10-22 |
| Improving Implementation of Guideline-Recommended LDL-C Management in High-Risk Cardiovascular Patients ASCVD | Not yet recruiting | Cardiology Consultants of Philadelphia | 2500 | 2026-10-01 | 2026-10-20 | |
| Prophylaxis for Emetogenic radioTherapy With Akynzeo Akynzeo - Palliative Cancer | Phase 2 | Not yet recruiting | University Health Network, Toronto | 188 | 2026-11-01 | 2026-10-20 |
| Comparison of HPI-guided Norepinephrine Boluses, ClearSight-guided Norepinephrine Infusion, and Oscillometric-guided Norepinephrine Infusion for Blood Pressure Stability During Cesarean Delivery Hypotension Prediction Index derived from the noninvasive arterial waveform, Continuous noninvasive arterial pressure monitoring (HPI blinded), Norepinephrine intermittent bolus - Hypotension During Cesarean Delivery, Blood Pressure Monitoring | Not applicable | Not yet recruiting | National Taiwan University Hospital | 180 | 2026-10-15 | 2026-10-20 |
| Parsing the Impact of Calories Versus Sweet Taste on Beverage Brand Conditioning 3-week daily beverage intervention - Neuropsychology, Ingestive Behavior | Not applicable | Not yet recruiting | Monell Chemical Senses Center | 176 | 2027-03-01 | 2026-10-20 |
| A Climate Change Education Program for 7th and 8th Grade Students in Istanbul Schools: Does It Improve Climate Knowledge and Health-Protective Behaviors? a climate change education for students in secondary school. - Climate Change, Adolescent | Not applicable | Not yet recruiting | Berk Öngider | 154 | 2026-10-20 | 2026-10-20 |
| Nurse-Led Self-Compassion Intervention for Women With Induced Menopause Nurse-Led Self-Compassion Intervention - Induced Menopause | Not applicable | Completed | Aya Ibrahim | 150 | 2026-01-15 | 2026-10-20 |
| Benmelstobart Plus Anlotinib Versus Sunitinib as First-Line Treatment for Advanced Non-Clear Cell Renal Cell Carcinoma Benmelstobart, Anlotinib, Sunitinib - Non-Clear Cell Renal Cell Carcinoma | Phase 3 | Active not recruiting | Sun Yat-sen University | 126 | 2025-06-01 | 2026-10-20 |
| Application of Chain Management Based on the IMB Model in Patients With Kinesiophobia Following Lumbar Fusion Surgery Basic Postoperative Care, chain management based on the Information-Motivation-Behavioral Skills model - Information-motivation-behavior Skills Model | Not applicable | Recruiting | Jiawei Jiang | 104 | 2024-02-01 | 2026-10-20 |
| Development of the '1 Situation-5 Minutes' Game and Evaluation of Its Impact on Care Awareness and Empathy: A Mixed-Methods Study "1 Situation-5 Minutes" game - Nursing Students' Care Awareness and Empathy | Not applicable | Not yet recruiting | Muş Alparslan University | 100 | 2026-10-01 | 2026-10-20 |
| Cognitive Effects of Hyperbaric Oxygen Therapy (HBOT) After a Traumatic Brain Injury Hyperbaric Oxygen Therapy - HBOT - Adults Who Sustained a Traumatic Brain Injury (TBI), Adults Who Treated With a Course of Hyperbaric Oxygen Therapy | Not yet recruiting | Assaf-Harofeh Medical Center | 1000 | 2026-10-01 | 2026-10-20 | |
| HMD-Based Virtual Reality Simulation in Nursing Skills Education Intervention 1 - Experimental Intervention, Intervention 2 - Control Intervention - Nursing Education Research, Nursing Education | Not applicable | Not yet recruiting | Giresun University | 90 | 2026-11-02 | 2026-10-20 |
| Immediate vs Conventional Loading With Different Crown Materials on Immediately Placed Single Implants Conventional loading, Monolithic zirconia crown, Permanent 3D-printed PMMA crown - Partial Edentulism, Dental Implant | Not applicable | Not yet recruiting | Ain Shams University | 80 | 2026-11-25 | 2026-10-20 |
| Pudendal Nerve Block for Pain Relief During Episiotomy Repair: A Randomized Controlled Trial Pudendal Nerve Block, Conventional Local Perineal Infiltration - Episiotomy , Perineal Pain | Not applicable | Not yet recruiting | Shaheed Zulfiqar Ali Bhutto Medical University | 80 | 2026-10-31 | 2026-10-20 |
| Home-Based Exercise Program for Diastasis Recti in Early Postpartum Women Standard Postpartum Education, 6-Week Home-Based Abdominal Exercise Program - Diastasis Recti Abdominis (Postpartum) | Not applicable | Completed | Medical University of Gdansk | 78 | 2025-07-01 | 2026-10-20 |
| The Effect of QR Code-Based Video Training on Knowledge Level, Self-Management, and Self-Efficacy in Patients With Urinary Catheters: A Randomized Controlled Study Patient education - Urinary Catheters, Nursing Care | Not applicable | Active not recruiting | Saglik Bilimleri Universitesi | 70 | 2026-09-01 | 2026-10-20 |
| Effect of Mannequin-Assisted Breast Examination Training on Midwifery Students Mannequin-Assisted Breast Examination Training, Routine Theoretical Breast Examination Education - Breast Examination Skills Training in Midwifery Students | Not applicable | Completed | Sinop University | 71 | 2025-10-01 | 2026-10-20 |
| Stereotactic Body Radiotherapy (SBRT) Induced Pancreatic Atrophy for Prevention of Post Operative Pancreatic Fistulae (POPF) After Pancreatoduodenectomy in Very High-Risk Patients (STEREOPANC) Remnant pancreas SBRT - Pancreatic Surgery, Prophylactic SBRT | Not applicable | Recruiting | Oulu University Hospital | 70 | 2026-03-02 | 2026-10-20 |
| Dynamic Versus Traditional Core Strengthening Exercises in Patients With Chronic Non-specific Low Back Pain Routine Physiotherapy, Dynamic Core Strengthening Exercises, Traditional Core Strengthening Exercises - Chronic Non-Specific Low Back Pain | Not applicable | Completed | University of Lahore | 70 | 2025-12-15 | 2026-10-20 |
| Prophylactic Ondansetron and Maternal Haemodynamics During Spinal Anaesthesia for Elective Caesarean Section Ondansetron 4 MG (Kemoset 4mg), Placebo - Hypotension Bradycardia Anesthesia, Spinal Cesarean Section | Not applicable | Completed | Aydin Adnan Menderes University | 66 | 2021-04-16 | 2026-10-20 |
| A Phase 1 Multiple Dose Trial in Healthy Adult Participants to Evaluate the Safety, Tolerability, Drug-Drug Interactions, and Pharmacokinetics of TBD11 TBD11 (300 mg), Placebo, Itraconazole (200 mg) - Healthy Adult Participants | Phase 1 | Recruiting | Gates Medical Research Institute | 66 | 2026-10-21 | 2026-10-22 |
| Effect of Vitamin D3 Supplementation on Serum Sphingosine-1-Phosphate Levels and Dental Implant Osseointegration: A Prospective Study Vitamin D3 ( Colecalciferol) - Dental Implant | Not applicable | Not yet recruiting | Air Force Military Medical University, China | 60 | 2026-10-30 | 2026-10-20 |
| Intervention Program for Psychological Well-Being in Institutionalized Older Adults Through Virtual Reality Active IVR Group, Passive IVR Goup - Healthy Volunteers, Aging, Healthy | Not applicable | Not yet recruiting | Francisco Antonio Nieto Escámez | 60 | 2026-10-15 | 2026-10-20 |
| Transesophageal Echocardiography in Conductive System Pacing in Pediatric Patients Left Bundle Branch Pacing - Left Bundle Branch Area Pacing | Not applicable | Not yet recruiting | Assiut University | 56 | 2026-12-01 | 2026-10-20 |
| PliaFX Flo Subtalar Fusion Study PliaFX Flo Allograft - Subtalar Arthrodesis | Early Phase 1 | Not yet recruiting | St. Paul's Hospital, Canada | 50 | 2026-10-01 | 2026-10-20 |
| Treating Barton Fracture-Dislocation Combined With Soft Tissue Compromise Fixation - Mayo Wrist Score | Not applicable | Completed | Xu Zhang | 48 | 2020-01-10 | 2026-10-20 |
| Classical Music, Pain, and Physiological Parameters in Children Undergoing Two Aspiration Procedures Classical Music Group - Endotracheal Aspiration, Tracheostomy Patients | Not applicable | Recruiting | Bandırma Onyedi Eylül University | 44 | 2025-11-02 | 2026-10-20 |
| Modified Thoracolumbar Interfascial Plane Block vs Retrolaminar Block for Pain in Lumbar Spine Surgeries Morphine, Bupivacaine, Dexamethasone - Postoperative Pain After Spinal Surgery | Not applicable | Recruiting | Zagazig University | 42 | 2025-10-01 | 2026-10-20 |
| Clinical Evaluation of Bioflx Crowns in Restoring Primary Anterior Teeth Bioflx Crown Restoration (Group I), Celluloid Strip Crown Restoration (Group II) - Clinical, Primary Teeth | Not applicable | Recruiting | Tanta University | 40 | 2025-11-09 | 2026-10-22 |
| Effects of Tele-rehabilitation-Guided Qigong on Children and Adolescents With Asthma Tele-rehabilitation-guided Qigong - Asthma Childhood | Not applicable | Not yet recruiting | Antalya Health Sciences University | 40 | 2026-10-15 | 2026-10-20 |
| Comparison of Fractional CO2 Laser Monotherapy and Its Combination With Either Topical Vitamin C or Topical Timolol in the Treatment of Post-Acne Erythema: A Split Face Study topical Timolol maleate 0.5% eye drops, topical Vitamin C 15%, Fractional CO2 laser - Post-acne Erythema | Phase 2 | Completed | Cairo University | 40 | 2023-08-30 | 2026-10-20 |
| Effect of Probiotics on Immunosuppressant Therapy in Kidney Transplant Recipients Probiotic formulation, Placebo - Kidney Transplantation, Kidney Transplantation Recipients | Not applicable | Completed | Federico II University | 40 | 2025-06-18 | 2026-10-20 |
| Chidamide, Lenalidomide, and Rituximab in Newly Diagnosed Elderly/unFit DE-DLBCL Chidamide in combination with Lenalidomide and Rituximab (CR2) - Double Expressor DLBCL, ELDERLY PEOPLE | Phase 2 | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 38 | 2024-03-11 | 2026-10-20 |
| Impact of Diabetes on Patients With Osteoporotic Vertebral Compression Fractures After Vertebral Augmentation: A Retrospective Cohort Study Percutaneous Vertebroplasty (PVP), Percutaneous Kyphoplasty (PKP) - Osteoporotic Vertebral Compression Fractures | Completed | The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine | 360 | 2024-09-01 | 2026-10-20 | |
| Comparison of Operative Hysteroscopy and Vacuum Aspiration for Terminating First-trimester Pregnancy With Intrauterine Adhesions Vacuum Aspiration Group, Hysteroscopy adhesiolysis combined with vacuum aspiration - Pregnancy Complicated With Intrauterine Adhesion | Recruiting | Women's Hospital School Of Medicine Zhejiang University | 360 | 2026-12-01 | 2026-10-20 | |
| Comparison of Three Osteotomy Techniques in Temporomandibular Joint Ankylosis Surgery Piezoelectric Surgical Device, Ultrasonic Bone Scalpel, Conventional Reciprocating Saw - Temporomandibular Joint Ankylosis | Not applicable | Completed | Ankara University | 32 | 2022-04-20 | 2026-10-20 |
| Autogenous and Xenograft Bone Mix in Alveolar Ridge Reconstruction 25% Autogenous + 75% Xenograft, 50% Autogenous + 50% Xenograft - Horizontal Alveolar Ridge Deficiency | Not applicable | Not yet recruiting | salah mohamed mohamed ibrahim ibrahim | 30 | 2026-10-01 | 2026-10-20 |
| Clinical and Radiographic Evaluation of E-IodoCal in Primary Molar Pulpectomy E-IodoCal Root Canal Obturation (Group I), Zinc Oxide-Eugenol Root Canal Obturation (Group II) - Pulpectomy, Pulpitis - Irreversible | Not applicable | Recruiting | Tanta University | 30 | 2025-11-25 | 2026-10-22 |
| Expanding the Spectrum of Adenosine Deaminase 2 (ADA2) Deficiency: Towards a Gene Therapy Approach bone marrow aspiration and biopsy - Adenosine Deaminase Deficiency | Not applicable | Completed | Istituto Giannina Gaslini | 29 | 2021-05-31 | 2026-10-20 |
| Study With Batten-1 (Miglustat Liquid Formulation) to Treat Ceroid Lipofuscinosis Neuronal 3 (CLN3) Disease Miglustat oral liquid formulation (250 mg/mL) - CLN3 | Phase 3 | Not yet recruiting | Beyond Batten Disease Foundation | 27 | 2026-12-01 | 2026-10-20 |
| AYUrvedic Foot Massage for Symtoms of Taxane-induced Peripheral nEuroPathy Manual manipulation of the feet. - Chemotherapy-induced Peripheral Neuropathy (CIPN) | Not applicable | Not yet recruiting | European Institute of Oncology | 20 | 2026-10-01 | 2026-10-20 |
| Fiber Soda on Postprandial Risk Factors Prebiotic soda followed by high-fat meal, Control beverage followed by high-fat meal - Healthy Participants | Not applicable | Recruiting | Ball State University | 20 | 2026-05-01 | 2026-10-20 |
| Transabdominal Versus Transvaginal Ultrasound at 9-14 Weeks in High-Risk Pregnancies Pregnancy at Increased Risk of Fetal Congenital Anomalies | Recruiting | Mohamed Mahrous Ahmed | 200 | 2026-07-01 | 2026-10-21 | |
| Evaluating the Effectiveness of an Adapted-Dialectical Behavior Therapy (A-DBT) Adapted Dialectical Behavioral Therapy (A-DBT) - Treatment | Not applicable | Completed | International Islamic University, Islamabad | 16 | 2025-03-01 | 2026-10-20 |
| Horizontal Ridge Augmentation in Atrophic Posterior Mandible With Delayed Implant Placement atrophied ridge augmentation - Atrophic Mandible | Not applicable | Completed | Mansoura University | 15 | 2023-11-01 | 2026-10-20 |
| Effects of Sedation Agents on Optic Nerve Sheath Diameter Procedural Sedation | Completed | Alanya Alaaddin Keykubat University | 73 | 2023-11-01 | 2026-10-20 | |
| Unraveling Dynamics and Clinical Impact of Tregs in Allogeneic HSCT With PTCy HSCT | Not yet recruiting | Ciceri Fabio | 70 | 2026-11-01 | 2026-10-20 | |
| AI-CLINIC: A Prospective Multisite Feasibility and Safety Study of AI-Assisted Pre-Consultation History-Taking in Outpatient Cardiology AI Interview - Symptom Tracking, Cardiology | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 60 | 2026-10-01 | 2026-10-20 |
Trials whose results were posted on ClinicalTrials.gov between 2026-10-15 to 2026-10-21.
| Trial | Posted | Phase | Sponsor |
|---|---|---|---|
| Building Resilience and Appropriate Independence in Young Adults With Autism Life Skills and Resilience Program | 2026-10-21 | Not applicable | University of California, San Francisco |
| Connect TF - An Investigation of Function and Usability of a New Adaptable Socket System CONNECT TF adaptable socket system, Any conventional handmade socket | 2026-10-21 | Not applicable | Össur Iceland ehf |
| Switching Individuals in Treatment for Opioid Use Disorder Who Smoke Cigarettes to the SREC Standardized research e-cigarette (SREC) | 2026-10-21 | Not applicable | Massachusetts General Hospital |
| Neurofeedback During Naturalistic Stimuli to Reduce Craving in Heroin Addiction Real-time fMRI Neurofeedback, Sham Real-time fMRI Neurofeedback | 2026-10-21 | Not applicable | Icahn School of Medicine at Mount Sinai |
| A Study to Evaluate the Efficacy and Safety of CBL-514 in Participants With EFP; Cellulite (Stage 1) 40 mg CBL-514, 60 mg CBL-514, 80 mg CBL-514 | 2026-10-21 | Phase 2 | Caliway Biopharmaceuticals Co., Ltd. |
| To Assess the Safety and Tolerability of Tafasitamab Alone or in Combination With Other Drugs in Japanese Participants With Non-Hodgkins Lymphoma (NHL) tafasitamab, lenalidomide, parsaclisib | 2026-10-21 | Phase 1 / Phase 2 | Incyte Biosciences Japan GK |
| Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma 1064 nm long-pulse Nd:YAG laser | 2026-10-21 | Not applicable | Christopher Zachary |
| Intravenous Methadone Versus Intrathecal Morphine for Analgesia Following Cesarean Delivery Intravenous line (IV) Methadone, Intrathecal Morphine | 2026-10-21 | Phase 4 | Mayo Clinic |
| Effects of Sleep Disruption on Drug Response Within-Subject test of blinded study medication | 2026-10-21 | Phase 2 | Johns Hopkins University |
| Sorafenib Induced Autophagy Using Hydroxychloroquine in Hepatocellular Cancer Sorafenib (SOR), Hydroxychloroquine (HCQ) | 2026-10-21 | Phase 2 | The University of Texas Health Science Center at San Antonio |
| FOLFIRINOX With Digoxin in Patients With Resectable Pancreatic Cancer Digoxin, 5Fluorouracil, Calcium Leucovorin | 2026-10-21 | Phase 2 | University of Nebraska |
| Randomized Evaluation of Patients Who Have Had Laparoscopic Partial Nephrectomy Hemostatic Agent, No Hemostatic Agent | 2026-10-21 | Not applicable | University of Chicago |
| Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax in Combination With Intravenous (IV) Obinutuzumab or Oral Ibrutinib in Adult Participants With Untreated Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) Venetoclax, Ibrutinib, Obinutuzumab | 2026-10-21 | Phase 2 | AbbVie |
| This Study Will Collect Clinical and Patient Reported Satisfaction Data From Males Requiring Urine Output Management Overnight in the Home Setting. PureWick® Urine Collection System, UltraFlex™ Self-Adhering Male External Catheter | 2026-10-21 | Not applicable | C. R. Bard |
| Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen (ARTISTRY-1) Bictegravir, Lenacapavir, BIC/LEN FDC | 2026-10-21 | Phase 2 / Phase 3 | Gilead Sciences |
| Cortical Network Modulation by Subthalamic Nucleus DBS Deep Brain Stimulation | 2026-10-21 | Not applicable | Washington University School of Medicine |
| Video Images About Decisions for Ethical Outcomes in the Emergency Department (VIDEO-ED) video decision aid, control arm ACP information sheet | 2026-10-21 | Not applicable | Massachusetts General Hospital |
| Electronic SBI(RT) for MSM in Argentina electronic screening and brief intervention., Phase 2: Assessment Only | 2026-10-21 | Not applicable | Florida State University |
| Electronic Quitline Referral With Enhanced Academic Detailing for the Promotion of Smoking Cessation Enhanced Academic Detailing, Informational Intervention | 2026-10-21 | Not applicable | OHSU Knight Cancer Institute |
| A Study Investigating the Efficacy and Safety of Intravitreal Injections of ANX007 in Patients With Geographic Atrophy ANX007, Sham comparator | 2026-10-21 | Phase 2 | Annexon, Inc. |
| Efficacy of a Vented Liner and Socket System for Individuals With Trans-femoral Amputation Vented suspension system, Non-vented suspension system | 2026-10-21 | Not applicable | Jóna Valgerður Kristjánsdóttir |
| A Study of Romosozumab (EVENITY®) in Postmenopausal Women in India With Osteoporosis at a High Risk of Fracture. Romosozumab | 2026-10-21 | Phase 4 | Amgen |
| Home-based tDCS in Frontotemporal Dementia or Alzheimer's Disease Computerized Cognitive Training, Active tDCS (tDCS) on DLPFC | 2026-10-21 | Not applicable | Johns Hopkins University |
| Lenvatinib, Pembrolizumab, and Paclitaxel for Treatment of Recurrent Endometrial, Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Lenvatinib, Paclitaxel, Pembrolizumab | 2026-10-21 | Phase 2 | Floor Backes, MD |
| Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL Brentuximab vedotin, Rituximab, Lenalidomide | 2026-10-21 | Phase 3 | Seagen, a wholly owned subsidiary of Pfizer |
| Biofeedback Based Virtual Reality Intervention to Manage Postoperative Pain Technology Based Intervention Group 1, Technology Based Intervention Group 2 | 2026-10-20 | Not applicable | Vanessa Olbrecht |
| Atezolizumab, Guadecitabine, and CDX-1401 Vaccine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Atezolizumab, DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Guadecitabine | 2026-10-20 | Phase 1 / Phase 2 | National Cancer Institute (NCI) |
| Examining the Role of the Orexin System in Sleep and Stress in Persons With Opioid Use Disorder Suvorexant, Placebos | 2026-10-20 | Phase 2 | Johns Hopkins University |
| Neoadjuvant PD-1 Inhibitor Dostarlimab (TSR-042) vs. Combination of Tim-3 Inhibitor Cobolimab (TSR-022) and PD-1 Inhibitor Dostarlimab (TSR-042) in Melanoma Dostarlimab (TSR-042) (singly), Dostarlimab (TSR-042) and TSR-022 (combination) | 2026-10-20 | Phase 2 | Diwakar Davar |
| Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers Nivolumab, Ipilimumab | 2026-10-20 | Phase 2 | Dana-Farber Cancer Institute |
| ElderTree Via a Voice Activated Device for Managing Chronic Health Conditions (NHLBI) ET-Text (Laptop), ET-Voice (Smart System) | 2026-10-20 | Not applicable | University of Wisconsin, Madison |
| Ketamine and Kidney Injury in Cardiac Surgery Ketamine, Propofol | 2026-10-20 | Phase 4 | Mayo Clinic |
| The Kentucky Viral Hepatitis Treatment Study Sofosbuvir/velpatasvir (Epclusa®) | 2026-10-20 | Phase 4 | Jennifer Havens |
| Translating Scientific Evidence Into Practice Using Digital Medicine and Electronic Patient Reported Outcomes Digital Transformation Network (DTN) Program | 2026-10-20 | Not applicable | Icahn School of Medicine at Mount Sinai |
| SELUTION SLR™ 014 In-stent Restenosis SELUTION SLR 014 DEB, Standard of Care | 2026-10-20 | Not applicable | M.A. Med Alliance S.A. |
| Anti-VEGF Therapy for Acute Thyroid Eye Disease Sub-tenon injection of saline followed by a sub-tenon injection of aflibercept, Sub-tenon injection of hyaluronidase (HA) followed by a sub-tenon injection of aflibercept, Sub-tenon injection of hyaluronidase (HA) alone | 2026-10-20 | Phase 2 | Massachusetts Eye and Ear Infirmary |
| A Clinical Study of Enlicitide in Participants With Severe Renal Impairment (MK-0616-032) Enlicitide | 2026-10-20 | Phase 1 | Merck Sharp & Dohme LLC |
| Study Assessing QBS72S For Treating Brain Metastases QBS72S | 2026-10-20 | Phase 2 | Melanie Hayden Gephart |
| Effects of Osteopathic Manipulative Treatment on Neuromuscular Control of the Head-neck System Osteopathic manipulative treatment, No intervention | 2026-10-20 | Not applicable | Michigan State University |
| A Study To Evaluate Hypofractionated Proton Therapy Or IMRT For Recurrent, Oligometastatic Prostate Cancer Intensity-Modulated Radiation Therapy, Proton Beam Radiation Therapy, Quality-of-Life Assessment | 2026-10-20 | Phase 2 | Mayo Clinic |
| A Study to Evaluate a Computerized Stethoscope Called ©Voqx to Diagnose Heart Disease ©VoqX stethoscope | 2026-10-20 | Not applicable | Mayo Clinic |
| Impact of Metformin on Immuno-virologic Parameters in HIV Metformin | 2026-10-20 | Phase 2 / Phase 3 | University of Hawaii |
| Corona Mortis in Patients Undergoing TEP for Inguinal Hernia TEP | 2026-10-20 | Sofia Med Hospital | |
| Suicide Prevention Integration Into Task-shifted Mental Health Interventions KPZ Program (KPZ), Enhanced Usual Care (EUC) | 2026-10-20 | Not applicable | Yale University |
| Outcomes of Partial Pulpotomy Treatment in Cariously Exposed Teeth Biodentine (calcium silicate-based cement) (Septodont, Saint Maur de Fossés, France), Theracal PT (resin modified calcium silicate-based cement) (Bisco Inc., Schaumburg, IL, USA) | 2026-10-20 | Phase 4 | Firat University |
| Testing a Barbershop-based HIV Prevention Initiative Among Men General, status-neutral HIV education, HIV self-test kits, Information about where to receive HIV prevention services | 2026-10-20 | Not applicable | HIV Prevention Trials Network |
| Neurocognitive Factors in EdTech Intervention Response GraphoLearn reading intervention, Math control intervention | 2026-10-20 | Not applicable | University of Connecticut |
| Confirming the Efficacy/Mechanism of Family Therapy for Children With Low Weight ARFID Family-based Treatment for ARFID, Manualized Non-Specific Usual Care for ARFID | 2026-10-20 | Not applicable | Stanford University |
| A Study of Ustekinumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis (UC) Ustekinumab Dose Based on BSA and Body Weight, Matching Placebo | 2026-10-20 | Phase 3 | Janssen Research & Development, LLC |
| Dynamic Airway CT is Diagnostic for Tracheomalacia in Children Dynamic Airway CT scan (DA-CT) | 2026-10-20 | Not applicable | NYU Langone Health |
| Prepare for Your Diabetes Care Prepare for Your Diabetes Care, Usual Care | 2026-10-20 | Not applicable | Kaiser Permanente |
| Golimumab and Apalutamide for the Treatment of Castration-Resistant Prostate Cancer, TRAMP Study Apalutamide, Biopsy, Biospecimen Collection | 2026-10-19 | Phase 2 | University of Washington |
| Families Becoming Healthy Together FBT, FBT+Variety | 2026-10-19 | Not applicable | The University of Tennessee, Knoxville |
| Blood-Brain Barrier Disruption Using Transcranial MRI-Guided Focused Ultrasound Transcranial ExABlate | 2026-10-19 | Not applicable | InSightec |
| Feasibility and Acceptability of the Propeller Monitoring System in Children With Persistent Asthma Propeller EMD | 2026-10-19 | Connecticut Children's Medical Center | |
| The Breakfast Study Breakfast | 2026-10-19 | Not applicable | University of Michigan |
| Study With Afuresertib and Paclitaxel in Platinum Resistant Ovarian Paclitaxel, Afuresertib | 2026-10-19 | Phase 2 | Laekna Limited |
| A Communication Tool to Improve Communication in the ICU Best Case/Worst Case-ICU Communication Tool | 2026-10-19 | Not applicable | University of Wisconsin, Madison |
| A Study of Rusfertide in Adults With Polycythemia Vera (PV) Rusfertide, Placebo | 2026-10-19 | Phase 3 | Protagonist Therapeutics, Inc. |
| IBIS Megastudy- Pilot Risk assessment messaging, U=U messaging, Healthy Living messaging | 2026-10-19 | Not applicable | University of California, San Francisco |
| A First in Human (FIH) Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DR10624 DR10624 for injection, Placebo | 2026-10-19 | Phase 1 | Zhejiang Doer Biologics Co., Ltd. |
| PortionSize Study 3: Assessment in Free-living Conditions | 2026-10-19 | Pennington Biomedical Research Center | |
| Evaluation of Aqueous Humor DEL-1 and IL-17 Levels in Diabetic Cataract Patients Observational Study Procedure | 2026-10-19 | Uşak University | |
| Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery CX 4945 | 2026-10-19 | Phase 1 / Phase 2 | Pediatric Brain Tumor Consortium |
| Nivolumab and BMS986205 in Treating Patients With Stage II-IV Squamous Cell Cancer of the Head and Neck Nivolumab, IDO1 Inhibitor BMS-986205, Therapeutic Conventional Surgery | 2026-10-19 | Phase 2 | Thomas Jefferson University |
| Clinical Study to Investigate the Ability of a Stannous Fluoride Toothpaste to Protect From Dentine Hypersensitivity Sensodyne Rapid Relief, Colgate Cavity Protection | 2026-10-19 | Not applicable | HALEON |
| A Study to Investigate Natural Killer Cell Engager (SAR443579) With Different Agents in Participants With Hematological Malignancies SAR443579, venetoclax, azacitidine | 2026-10-19 | Phase 1 / Phase 2 | Sanofi |
| Treating Primary Progressive Aphasia (PPA) Using High-definition tDCS high-definition transcranial direct current stimulation, modified constraint-induced language therapy | 2026-10-19 | Phase 2 | University of Pennsylvania |
| EO4010 in Previously Treated Metastatic Colorectal Carcinoma EO4010 | 2026-10-19 | Phase 1 / Phase 2 | Enterome |
| Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism anastrozole (1 mg/day), Placebo | 2026-10-19 | Phase 4 | Baylor College of Medicine |
| Phase 2B Study Assessing Pain Relief After Replacement of the Knee ATX101, bupivacaine hydrochloride, saline placebo | 2026-10-19 | Phase 2 | Allay Therapeutics, Inc. |
| A Drug-Drug Interaction Study to Assess the Pharmacokinetics of DC-806 When Orally Administered Alone, When Coadministered With Itraconazole, and When Coadministered With Carbamazepine in Healthy Adult Participants DC-806, Itraconazole, Carbamazepine | 2026-10-19 | Phase 1 | DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company |
| A Drug-Drug Interaction Study Evaluating the Perpetrator Potential of DC-806 on Cocktails of CYP450 Enzyme and Transporter Substrates in Healthy Participants DC-806, Midazolam, Repaglinide | 2026-10-19 | Phase 1 | DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company |
Trials whose overall status changed between 2026-10-15 to 2026-10-21 (started recruiting, completed, suspended, terminated, withdrawn...), with the reason when one was given.
| Trial | Change | Phase | Sponsor |
|---|---|---|---|
| Building Resilience and Appropriate Independence in Young Adults With Autism Life Skills and Resilience Program | Unknown → Completed | Not applicable | University of California, San Francisco |
| Effect of TECAR Therapy on Balance and Quality of Life in Elderly Men With Knee Osteoarthritis True TECAR Therapy, Sham TECAR, Traditional Physiotherapy | Not yet recruiting → Completed | Not applicable | Middle East University |
| Study to Investigate the Efficacy and Safety of Regimens Containing BRII-179, BRII-835, and PEG-IFNα Treating Chronic Hepatitis B Virus (HBV) Infection (ENRICH) BRII-179, BRII-835 (VIR-2218), PEG-IFNα | Active not recruiting → Completed | Phase 2 | Brii Biosciences Limited |
| Quality of Life in Children After Multisystem Inflammatory Syndrome in Children | Enrolling by invitation → Completed | Kristina Lah Tomulić | |
| Garlic Product Impact on Periodontitis (GPIP) Aged Garlic Extract | Unknown → Completed | Not applicable | Hadassah Medical Organization |
| "Machine Learning Analysis of Lingual Colorimetry and MADRS Anxiety-Depression Score in Acupuncture Patients" | Recruiting → Completed | Dr Benoit Bataille | |
| A Study to Test Experimental Blood Stage Malaria Vaccine in Burkina Faso. Rabies vaccine, RH5.1 10μg adjuvated with 50μg Matrix-M, RH5.2 5μg adjuvated with 50μg Matrix-M | Recruiting → Completed | Phase 1 / Phase 2 | University of Oxford |
| AMBULAPSE STUDY Feasibility Study on Laparoscopic Double-mesh Sacrocolpopexy With or Without Robotic Assistance, in Female Patients Presenting With Symptomatic Pelvic Organ Prolapse, Based on an Outpatient Treatment Model. outpatient laparoscopic | Recruiting → Completed | Not applicable | Centre Hospitalier Universitaire de Nice |
| Resistance Exercise With Blood Flow Restriction by Vascular Occlusion on Myocardial Function in Heart Failure With Reduced Ejection Fraction Application of a vascular restriction device during resistance training | Not yet recruiting → Recruiting | Not applicable | Centre Hospitalier Universitaire de Nīmes |
| Changes in Periodontal Pocket Depth After Periodontal Treatment Periodontal Treatment | Recruiting → Completed | Not applicable | Necmettin Erbakan University |
| Mechanisms of Anaphylaxis Biomarkers (platelet activating factor [PAF], anaphylatoxins) and basophil activation test (BAT) | Unknown → Active not recruiting | Haukeland University Hospital | |
| Exploratory Study on Bio-signal Telemonitoring Using Electronic Textiles in a Pediatric Acute and Critical Care Setting Skiin pediatric band and Skiin biometric pod | Unknown → Recruiting | The Hospital for Sick Children | |
| Peer Support in Alcohol Dependence Quality life questionnaire AQoLS, Quality life questionnaire Euroqol EQ-5D-5L, Peer support consultations | Not yet recruiting → Recruiting | Not applicable | Hospices Civils de Lyon |
| Evaluation of the Effectiveness of Patient Therapeutic Education on Chronic Insomnia therapeutic education, Actimetry | Recruiting → Completed | Not applicable | Centre Hospitalier Universitaire de Nīmes |
| Just-in-Time Coping Prompts for Reactive Digital Behavior in College Students Momentary coping prompt, Active control message | Not yet recruiting → Recruiting | Not applicable | University of Florida |
| Myofunctional Therapy for Children With OSA Myofunctional therapy | Not yet recruiting → Recruiting | Not applicable | Chinese University of Hong Kong |
| Laser Therapy for Dentin Hypersensitivity Er,Cr;YSGG Laser, Waterlase, Biolase Technology Inc., Irvine, CA, ABD, Remin Pro (VOCO, Cuxhaven, Germany) | Active not recruiting → Completed | Not applicable | Hacettepe University |
| A Study to Investigate the Effects of Zovaglutide (ZT002 Injection) on QTc Interval in Healthy Adults ZT002 injection, ZT002 injection matching placebo | Not yet recruiting → Active not recruiting | Phase 1 | Beijing QL Biopharmaceutical Co.,Ltd |
| BaLloon-based PFA Ablation poST Approval Outcomes for PAF and PersAF Pulsed Field Ablation | Recruiting → Active not recruiting | Not applicable | Abbott Medical Devices |
| Preterm Infants on Early Solid Foods Early intervention group, Late intervention group | Unknown → Completed | Not applicable | Medical University of Vienna |
| TRIFORMIS RESILIA Real-world Study Assessing Safety and Performance (TRIBLAZE Study) Edwards TRIFORMIS RESILIA heart valve | Not yet recruiting → Recruiting | Edwards Lifesciences | |
| Respiratory Virus Metagenomics After COVID-19 | Recruiting → Active not recruiting | Chinese University of Hong Kong | |
| SPSIP Block in Shoulder Artroscopy SPSIPB block | Not yet recruiting → Recruiting | ULSS6 - Ospedale di Piove di Sacco | |
| Development of a Precision Nutrition Expert System Combining AI Dietary Image Recognition and Big Data Analysis: A Case Study on Kidney Disease CKDcare | Active not recruiting → Completed | Not applicable | China Medical University Hospital |
| Point-of-Care Troponin Testing in the Emergency Department Point-of-Care high-sensitivity troponin testing | Recruiting → Active not recruiting | Not applicable | KU Leuven |
| Glucose Disturbances in Premature Infants and Quality of Life | Unknown → Completed | Clinical Hospital Center Rijeka | |
| Evaluation of Balance Using the Biodex Balance System Among Different Subcategories of Low Back Pain Assessment of balance will be measured by The Biodex Balance System (BBS) which computes Postural Stability key indices: the medial-lateral stability index (MLSI), anterior-posterior stability index | Not yet recruiting → Completed | Not applicable | Cairo University |
| Aging Stereotypes and Prodromal Alzheimer's Disease Diagnosis of MCI versus No MCI (SCI or healthy patient) | Unknown → Completed | Not applicable | Assistance Publique Hopitaux De Marseille |
| Adolescents and Young Adults With Cancer: Their Preferred Involvement in Decision Making Clinical Decision-Making Scenarios and Preferences Assessment | Recruiting → Completed | Not applicable | Stanford University |
| The Effect of Blood Carboxyhemoglobin Levels on NF-kB, NRF2 and PGC-1α During Low-flow and Normal-flow Anesthesia low-flow anasthesia, Normal akımlı anestezi | Recruiting → Completed | Not applicable | Ataturk Training and Research Hospital |
| Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation JDQ443, trametinib, Ribociclib | Active not recruiting → Terminated Business reasons and not based on any safety concerns. | Phase 1 / Phase 2 | Novartis Pharmaceuticals |
| Study of PN20 in Adult Patients With Primary Immune Thrombocytopenia (ITP) PN20 treatment | Recruiting → Completed | Phase 1 | Chongqing Peg-Bio Biopharm Co., Ltd. |
| Correlation and Clinical Utility of Urinary Biomarker in Membranous Glomerulonephritis urinary markers | Unknown → Recruiting | Chinese University of Hong Kong | |
| Aortic Dissection Detection Risk Score With D-dimer to Rule-Out Acute Aortic Syndrome D-dimer test | Not yet recruiting → Recruiting | Chinese University of Hong Kong | |
| Effects of Reflexology and Cold Application Before Chest Tube Removal in CABG Patients Reflexology, Cryotherapy alone | Recruiting → Completed | Not applicable | Ankara University |
| REDUCTION ACCURACY IN NASO-ORBITO-ETHMOIDAL FRACTURES AFTER VIRTUAL REDUCTION AND FIXATION USING PRE-ADAPTED MINIPLATES pre-adapted titanium miniplates based on a virtually reduced 3D model | Recruiting → Completed | Phase 4 | Alexandria University |
| Investigating The Potential Of A Hay-Aged Cheese To Reduce Cholesterol As Mediated By Changes In The Gut Microbiome Hay-aged cheese, Cheddar control | Recruiting → Active not recruiting | Not applicable | Anisha Wijeyesekera |
| A Prospective Study of Cardiovascular Risk of Patients Admitted for Acute Exacerbation of COPD Intervention Group, Usual Care | Not yet recruiting → Recruiting | Not applicable | Chinese University of Hong Kong |
| EFFECT OF MULLIGAN CERVICAL SUSTAINED NATURAL APOPHYSEAL GLIDE ON POSTURAL STABILITY IN PATIENTS WITH CHRONIC NECK PAIN 1- The Biodex Balance System (BBS), 2-The Numerical Pain Rating Scale (NPRS), 3- The Neck Disability Index (Arabic version) for functional disability | Not yet recruiting → Recruiting | Not applicable | Menna Allah Ahmed Marei Elnaggar |
| Pharmacokinetic, Safety and Immunogenicity Study of New Process CMAB015 and Cosentyx in Healthy Volunteers Secukinumab 150mg s.c. | Active not recruiting → Completed | Phase 1 | Taizhou Mabtech Pharmaceutical Co.,Ltd |
| EFFICACY OF ARTIFICIAL INTELLIGENCE DRIVEN PROGRAM VERSUS TRADITIONAL PHYSICAL THERAPY PROGRAM IN PATIENTS WITH LOW BACK DYSFUNCTION AI-Driven Rehabilitation Program, Traditional Physical Therapy Program | Not yet recruiting → Recruiting | Not applicable | Cairo University |
| Smoking Relapse Prevention in Patients With Cancer Standardized Brief Relapse-Prevention Counseling, Add-on One-Session Structured CBT-Based Relapse-Prevention Counseling | Not yet recruiting → Recruiting | Not applicable | Vietnam National Cancer Hospital |
| Contribution of a Virtual Reality Program in the Treatment of Dysmorphophobia for Adolescent Female With Anorexia Nervosa self-evaluation of the Body Mass Index, Cognitive-behavioral psychotherapies | Unknown → Completed | Not applicable | Assistance Publique Hopitaux De Marseille |
| Clinical Cohorts for Validation of New Digital Biomarkers | Unknown → Completed | Atrial Fibrillation Network | |
| Down Sizing Strategy (HANGZHOU Solution) vs Standard Sizing Strategy TAVR in Bicuspid Aortic Stenosis (Type 0) TAVR for BAV Using Down Sizing with the Evolut Pro platform, TAVR for BAV Using Traditional Sizing strategy with the Evolut Pro platform | Recruiting → Active not recruiting | Not applicable | Second Affiliated Hospital, Zhejiang University, School of Medicine |
| A Phase I/II, First-in-Human Study to Evaluate TJ102 in Participants With Advanced or Metastatic Ovarian Cancer and Other Solid Tumors. TJ102 | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | Phrontline Biopharma |
| Effectiveness of Positive Deviance/Hearth in Treating Uncomplicated Moderate Acute Malnutrition in Children 6-59 Months in Mymensingh Division, Bangladesh PD/Hearth is a behavioral change program that teaches caregivers how to cook and feed their children. A nutrient-dense meal using local ingredients will be fed to children during Hearth sessions., Standard of Care (Investigator Selected) | Not yet recruiting → Enrolling by invitation | Not applicable | World Vision US |
| Biomarkers in Apical Periodontitis laser activation, PUI, CSI | Not yet recruiting → Completed | Not applicable | Kırıkkale University |
| Aleniglipron Phase 2 in Type 2 Diabetes Mellitus Aleniglipron, Placebo | Active not recruiting → Completed | Phase 2 | Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics |
| Robotic Systems Evaluation for Peripheral Pulmonary Lesions (RISE Trial) RAB via the Monarch platform, RAB via the ION platform | Not yet recruiting → Recruiting | Not applicable | Case Comprehensive Cancer Center |
| Personalized Analgesia Through Central Nervous System Engagement to Unlock Performance Duloxetine, Placebo | Not yet recruiting → Recruiting | Phase 4 | Benedict Alter |
| Recovery, Analgesia And Delirium Profiles At Laparoscopic Abdominal and Gynecologic Surgeries With Processed EEG Monitoring Bispectral index monitoring | Not yet recruiting → Completed | Not applicable | Cukurova University |
| Virtual hIStology of Crohn's Disease Ex-vivo Resected Anatomical Lesions | Not yet recruiting → Recruiting | Central Hospital, Nancy, France | |
| The Combined Effect of N-Acetyl Cysteine and Metformin in Polycystic Ovary Syndrome Patients N-acetyl cysteine, Metfomin | Recruiting → Completed | Phase 3 | Cairo University |
| A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative Colitis SAR441566, SAR441566 matching Placebo | Active not recruiting → Terminated Business decision | Phase 2 | Sanofi |
| Preeclampsia Research on Vitamin D, Inflammation, & Depression mental health screening, education and referral program | Unknown → Active not recruiting | Not applicable | Cedars-Sinai Medical Center |
| Quantification of Motor Compensation Following Biomechanical, Proprioceptive and Physiological Alterations Post-lower Limb Amputation. Biomechanics, Physiological, Proprioceptive | Recruiting → Completed | Centre Hospitalier Universitaire de Nīmes | |
| Grafting of the Peri-implant Bony Defects Around Immediate Implants Using Xenogenic Versus Alloplastic Sticky Grafts Immediate dental implant with filling the peri implant gap with xenogenic sticky bone | Recruiting → Completed | Not applicable | Cairo University |
| Improve Muscle Weakness in Patient With COPD Aerobic Exercise Combined with Blood Flow Restriction, Aerobic exercise | Not yet recruiting → Withdrawn no participant enrolled | Not applicable | Al-Zaytoonah University of Jordan |
| Fetal Treatment of Galenic Malformations Fetal embolization of vein of Galen malformation using Target XL and XXL Detachable Coils | Active not recruiting → Completed | Not applicable | Darren Orbach |
| The Food Network Effect Food Related Visual Stimuli Exposure | Not yet recruiting → Recruiting | Not applicable | Casey Morehouse, DO |
| Circadian Rhythm and Cardiovascular Recovery After Submaximal Exercise | Not yet recruiting → Recruiting | Saglik Bilimleri Universitesi | |
| Prevalence of Sleep Apnoea in Adolescents | Unknown → Completed | Chinese University of Hong Kong | |
| HD Patients' Depression and Happiness | Unknown → Completed | Chang Gung University of Science and Technology | |
| Normal Saline Versus Heparin Intermittent Flushing for the Prevention of Occlusion in Port-a-Cath Normal Saline Flush 20 ml, Normal Saline Flush 10 ml, Heparin Flush (1000 USP, 10ml) | Unknown → Completed | Not applicable | Chang Gung Memorial Hospital |
| The Vitamin D in Pediatric Crohn's Disease ( ViDiPeC-2 ) vitamin D3 | Unknown → Terminated Enrollment stopped at 55 of 316 planned participants due to recruitment challenges related to the COVID-19 pandemic and funding constraints. All enrolled participants completed 52-week follow-up. | Phase 3 | Jantchou Prevost |
| The Effect of Education on Quality of Life, Adherence to Immunosuppressive Therapy and Symptom Control in Organ Transplant Patients Mobile application installation, Providing teaching booklets, Control | Not yet recruiting → Recruiting | Not applicable | Ondokuz Mayıs University |
| PICNIC Study - PatIent Centered aNtIbiotic Courses in Children With Medical Complexity Clinical Stability Assessment | Recruiting → Completed | Not applicable | Boston Children's Hospital |
| Ultrasound Guided Combined Adductor Canal, Superior Genicular Nerves and Anterior Femoral Cutaneous Nerves Blocks in Comparison With Periarticular Local Anesthesia Infiltration in Primary Total Knee Arthroplasty Periarticular Infiltration, Ultrasound-Guided Triple Block Technique | Completed → Not yet recruiting | Not applicable | SAMEH ELSHERBINI |
| Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis Vamifeport, Placebo | Recruiting → Active not recruiting | Phase 2 | CSL Behring |
| Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer Merck 3475 Pembrolizumab, Intraoperative radiation therapy (IORT) | Unknown → Completed | Phase 1 | Columbia University |
| Continuous Glucose Monitoring in Patients With Diabetes on Peritoneal Dialysis | Unknown → Recruiting | Coordinación de Investigación en Salud, Mexico | |
| Safe and Timely Antithrombotic Removal (STAR) Registry CytoSorb | Recruiting → Active not recruiting | CytoSorbents, Inc | |
| Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder Kenetik, magnetic resonance imaging scan, Alcohol bar lab | Not yet recruiting → Recruiting | Phase 2 / Phase 3 | University of Pennsylvania |
| Online-Delivered Core Stability Exercises in Postpartum Women online core stability exercise group, an education-only control group | Not yet recruiting → Enrolling by invitation | Not applicable | Prince Sattam Bin Abdulaziz University |
| Barriers Limiting OCT Penetration in Clinical Practice | Recruiting → Completed | Consorzio Futuro in Ricerca | |
| Frailty and Ultrasound-Guided Central Venous Catheterization Difficulty in Adult Cardiac Surgery Patients Ultrasound-Guided Internal Jugular Vein Catheterization | Not yet recruiting → Recruiting | Ankara City Hospital Bilkent | |
| Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma 1064 nm long-pulse Nd:YAG laser | Active not recruiting → Completed | Not applicable | Christopher Zachary |
| A Study to Learn How Different Preparations of Osivelotor Taste and Enter the Blood With Food or Liquids or With an Antacid in Healthy Adults Osivelotor, Famotidine | Not yet recruiting → Recruiting | Phase 1 | Pfizer |
| Breathwork and Stress: Investigating the Mechanisms of Action and Effectiveness of Breathing Interventions in Modulating the Psychophysiological Response to Acute Stress Test Coherent Breathing (6 bpm), Sham Breathing (15 bpm) | Active not recruiting → Completed | Not applicable | Medical University of Bialystok |
| Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy (PROTECT-2) Mechanical thrombectomy combined with ischemic post-conditioning, Mechanical thrombectomy alone | Recruiting → Completed | Phase 2 | Capital Medical University |
| Bisacodyl Oral for Lowering Dysfunction (of Tenckhoff Catheter) Bisacodyl 5 mg | Not yet recruiting → Recruiting | Phase 4 | Chinese University of Hong Kong |
| Ventilator Trigger Sensitivity Adjustment Versus Threshold Inspiratory Muscle Training on Arterial Blood Gases Threshold inspiratory muscle trainer or ventilator pressure setting inspiratory muscle training techniques | Recruiting → Completed | Not applicable | Cairo University |
| The Effect of Mobile Application-Based Education Developed According to Orem's Self-Care Model in Multiple Myeloma Patients Mobile App Education | Active not recruiting → Completed | Not applicable | Ozlem |
| Neuropsychological Care for Maintaining Quality of Life After Radiation Therapy in Patients With Brain Metastases Best Practice, Neuropsychological Assessment, Quality-of-Life Assessment | Active not recruiting → Completed | Phase 2 | Ohio State University Comprehensive Cancer Center |
| Efficacy and Safety of Budesonide MMX® vs. Budesonide CR for Induction of Remission in Microscopic Colitis Budesonide MMX®, Budesonide controlled ileal release (CR) capsules | Not yet recruiting → Active not recruiting | Phase 2 | University of Calgary |
| Autoantibodies on Spinal Cord Injury Blood collection | Unknown → Completed | Hospital Nacional de Parapléjicos de Toledo | |
| Effect of Tiotropium on Airway Remodeling in Patients With Early Stage COPD Accessed by Optical Coherence Tomography Tiotropium Inhalation Powder [Spiriva] 0.018mg, Salbutamol sulphate aerosol (Ventolin) 0.1mg | Unknown → Completed | Not applicable | Guangzhou Institute of Respiratory Disease |
| Improving Outcome of Selected Patients With Non-resectable Hepatic Metastases From Colo-rectal Cancer With Liver Transplantation Liver transplant, Chemotherapy | Unknown → Completed | Phase 2 | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
| Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors PF-07220060, Letrozole, Fulvestrant | Active not recruiting → Recruiting | Phase 1 / Phase 2 | Pfizer |
| Thailand Birth and Infant Outcomes Study | Not yet recruiting → Active not recruiting | Mead Johnson Nutrition | |
| Motor Performance Improvement After Visual Rehabilitation Virtual Reality rehabilitation | Recruiting → Completed | Not applicable | Instituto de Investigación Sanitaria Aragón |
| Investigation of the Effects of Tele-Yoga Training in Individuals With Lung Cancer Undergoing Lung Resection Surgery Tele-Yoga Training | Recruiting → Completed | Not applicable | Istanbul University |
| Psoas Tenotomy Under Ultrasound Psoas tenotomy under ultrasound | Recruiting → Terminated Failure of the surgical procedure under investigation to achieve satisfactory results. | Not applicable | Centre Hospitalier Universitaire de Nice |
| SINUS WASH Pilot Study in Adults Testing Positive for COVID-19 Povidone-Iodine, Normal saline | Unknown → Completed | Phase 1 | Hampshire Hospitals NHS Foundation Trust |
| Positional Therapy for Childhood Obstructive Sleep Apnoea Positional device, Rematee Bumper Belt or Night Shift | Recruiting → Completed | Not applicable | Chinese University of Hong Kong |
| A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 Combined With R21/Matrix-M (a "Multi-stage" Malaria Vaccine) R21, RH5.1, R78C | Recruiting → Active not recruiting | Phase 1 | University of Oxford |
| A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™ R21/Matrix M™ (Group 1), R21/Matrix M™ (Group 2), R21/Matrix M™ (Group 3) | Active not recruiting → Completed | Phase 1 | University of Oxford |
| Expanded Studies on the SCAPIS Stockholm Reexamination Cohort Coronary computer tomography (CCTA), Echocardiograhy and aortic ultrasound, Liver elastography | Recruiting → Active not recruiting | Danderyd Hospital | |
| MENA Regional Endovascular Intervention for Venous Cerebral Venous Sinus Thrombosis Endovascular Thrombectomy, Anticoagulation Therapy | Not yet recruiting → Recruiting | Not applicable | Middle East North Africa Stroke and Interventional Neurotherapies Organization |
| ACT-GLOBAL IA Thrombolysis(ACT-REACT-004)Domain Within the ACT-GLOBAL Adaptive Platform Trial-NCT06352632 Tenecteplase or Alteplase- depending upon availability at each treating centre, Control | Not yet recruiting → Recruiting | Phase 3 | University of Calgary |
| Accuracy Testing of Validated and Non-validated Home BP Devices Sold on the Online Market. awake ABPM | Recruiting → Completed | Not applicable | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal |
| Handheld US Device to Verify Vascular Cannulation Sonosite, Lumify® | Enrolling by invitation → Active not recruiting | Not applicable | Alok Moharir |
| RESOLUTE ONYX China RCT Study Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System, Resolute Integrity™ Zotarolimus-Eluting Coronary Stent System | Active not recruiting → Completed | Not applicable | Medtronic Vascular |
| Exploring the Effects of Transcutaneous Electrical Acupoint Stimulation Therapy on Patients After Video-Assisted Thoracoscopic Surgery Standard Analgesia, Transcutaneous Electrical Nerve Stimulation (TENS), Transcutaneous Electrical Acupoint Stimulation (TEAS) | Enrolling by invitation → Completed | Not applicable | Buddhist Tzu Chi General Hospital |
| IV-X Medical Peripheral Intravascular Lithotripsy Study for PAD IV-X Medical IVL System | Withheld → Not yet recruiting | Not applicable | IVX Medical |
| To Evaluate Whether IVUS-guided Drug-eluting Stent (DES) Implantation Leads to Better Clinical Outcomes Compared to Conventional Angiography in the Treatment of Chronic Complete Occlusion (CTO) Disease. The guidewire successfully passed the CTO lesion | Recruiting → Active not recruiting | Not applicable | CCRF Inc., Beijing, China |
| Pembrolizumab + MRGOO3 as Neoadjuvant in NPC Pembrolizumab & MRG003 | Not yet recruiting → Active not recruiting | Phase 2 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology |
| Post-operative Medium Chain Triglyceride Diet May Reduce Hospital Stay Following Lung Resection MCT Diet | Recruiting → Not yet recruiting | Not applicable | Chinese University of Hong Kong |
| Prevention of COVID-19 Infection to Severe Pneumonia or ARDS EC-18, Placebo | Withdrawn → Not yet recruiting | Phase 2 | Enzychem Lifesciences Corporation |
| Site of Tracheal Extubation and Operating Room Efficiency During Robot-assisted Surgery Extubation in post-anesthesia care unit (PACU), Extubation in operating room (OR) | Recruiting → Completed | Not applicable | Peking University First Hospital |
| A Study of SHR-2906 Injection in Healthy Subjects With a Single Dose and in Obese Patients With Multiple Doses SHR-2906 Injection, SHR-2906 Injection Placebo | Recruiting → Active not recruiting | Phase 1 | Beijing Suncadia Pharmaceuticals Co., Ltd |
| A Clinical Trial Comparing the Efficacy and Safety of Different Doses of BL0175 Injection in Treating Postmenopausal Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Locally Advanced or Metastatic Breast Cancer BL0175 Injection | Not yet recruiting → Recruiting | Phase 2 | Shanghai Best-Link Bioscience, LLC |
| Research on Key Interventional Technologies for Controlling the Epidemic in High-prevalence Areas of Tuberculosis in Guangxi, China Active case finding | Recruiting → Completed | Not applicable | University of Toronto |
| A Study of MK-1484 as Monotherapy and in Combination With Pembrolizumab (MK-3475) In Advanced or Metastatic Solid Tumors (MK-1484-001) MK-1484, Pembrolizumab | Active not recruiting → Terminated Business Reasons | Phase 1 | Merck Sharp & Dohme LLC |
| Effectiveness and Cost-Effectiveness of a Digital Care Pathway and Asynchronous Communication for Patients With Hypertension Digital care pathway for hypertension, Asynchronous communication with nurse | Not yet recruiting → Recruiting | Not applicable | Wellbeing Services County of Pirkanmaa |
| A Study to Compare Pharmacokinetics, Efficacy and Safety of Subcutaneous CT-P44 and Darzalex Faspro in Combination With Lenalidomide and Dexamethasone in Patients With Refractory or Relapsed Multiple Myeloma CT-P44(Daratumumab), Darzalex Faspro(Daratumumab) | Recruiting → Active not recruiting | Phase 3 | Celltrion |
| Factor In the Initial Resuscitation of Severe Trauma 2 Patients Fibrinogen + PCC, Frozen Plasma | Unknown → Terminated Upon IDSMC's review of interim data, they recommended the trial be stopped based on futility. | Phase 4 | University Health Network, Toronto |
| Randomized Evaluation of Patients Who Have Had Laparoscopic Partial Nephrectomy Hemostatic Agent, No Hemostatic Agent | Active not recruiting → Completed | Not applicable | University of Chicago |
| Effectiveness of Ultrasound-guided Scalp Block for Supratentorial Craniotomy Ultrasound-guided scalp block with ropivacaine 0.375% | Unknown → Completed | Not applicable | University Malaysia Sarawak |
| Atopy Network - Comprehensive Allergy Centers: Medical Care of Patients With Moderate to Severe Allergic Diseases not applicable, observational study | Unknown → Recruiting | Charite University, Berlin, Germany | |
| Quit2Heal Smartphone App in Helping Cancer Patients Quit Smoking Quit2Heal, QuitGuide, Survey Administration | Active not recruiting → Completed | Not applicable | Fred Hutchinson Cancer Center |
| Intelligent Sports Injury Prevention and Training System Lower extremity and core muscle training | Unknown → Recruiting | Not applicable | National Taiwan University Hospital |
| Microbiome and Metabolomics Profiling in Children With OSA | Unknown → Recruiting | Chinese University of Hong Kong | |
| Efficacy and Safety of Methylene Blue in the Treatment of Severe Septic Shock Methylene Blue Intervention Group, Normal Saline Control Group | Unknown → Recruiting | Not applicable | First Affiliated Hospital of Zhejiang University |
| Backward Walking and Related Factors in Individuals With Stroke Assesment | Not yet recruiting → Completed | Gaziantep Islam Science and Technology University | |
| Early Temporal Dynamics of Optic Nerve Sheath Diameter After Therapy in GCA Optic Nerve Sheath Ultrasound, Temporal artery ultrasound, Bloodwork : CRP and ESR | Not yet recruiting → Recruiting | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | |
| Bed Bridge Test in Acute Stroke Patients Assesment test for Validity and Reliability | Not yet recruiting → Completed | Gaziantep Islam Science and Technology University | |
| Comparison of Exergaming Training With Visual Feedback Training on Upper Limb Functions in Post Stroke Patients Exergaming Training, Visual Feedback Training | Unknown → Completed | Not applicable | Riphah International University |
| A Real-world Study of the Effectiveness of Angiotensin Receptor-Neprilysin Inhibitor Therapy in Hypertensive Patients in the United Arab Emirates | Not yet recruiting → Recruiting | Novartis Pharmaceuticals | |
| Hyperangulated vs Macintosh Blades for Intubation With Videolaryngoscopy in ICU Hyperangulated blade videolaryngoscope, Macintosh blade videolaryngoscope | Recruiting → Completed | Not applicable | Hospital Clinico Universitario de Santiago |
| Comparison of Two Methods of Immunoprophylaxis Against RSV in Term Newborns to compare vaccine and monoclonal antibody | Active not recruiting → Completed | Jean-Michel HASCOET | |
| Shade Matching and Patient Satisfaction of Yttria Stabilized Multilayered Zirconia and Lithium Disilicate Restorations Yttria stabilized multilayered (YML) zirconia restorations, Lithium disilicate restorations | Unknown → Completed | Not applicable | Cairo University |
| Peripheral Nerve Stimulation Therapy for Atrial Fibrillation Wrist Device, Ear Device, Sham Device | Unknown → Terminated The Sponsor and Principal Investigator have mutually agreed to initiate study closure due to prolonged recruitment challenges that have prevented the trial from meeting its enrollment milestones within the projected study timeline. | Not applicable | Cala Health, Inc. |
| Efficacy of Diacylglycerol Oil on Metabolic Risk Factors in Prediabetes Diacylglycerol oil, Colza Oil | Not yet recruiting → Recruiting | Not applicable | The First Affiliated Hospital of Guangdong Pharmaceutical University |
| Evaluation of the Use of a Biodegradable Endoprothesis in the Prevention of Post-Endoscopic Retrograde CholoangioPancreatography Pancreatitis Placement of ARCHIMEDES fast biodegradable stent during the Endoscopic Retrograde CholoangioPancreatography | Recruiting → Completed | Not applicable | Institut Paoli-Calmettes |
| Comparison of Two Different Dual-Task Training Methods in Patients With Parkinson's Disease Single Task Exercise Training, Motor-Motor Dual Task Exercise Training, Cognitive-Motor Dual Task Exercise Training | Recruiting → Completed | Not applicable | Saglik Bilimleri Universitesi |
| Robotic RVO Trial: Robot-assisted Retinal Vein Cannulation in Patients With Retinal Vein Occlusions Surgery with Preceyes Robot plus NHS standard of care | Active not recruiting → Recruiting | Not applicable | University of Oxford |
| A Phase 1, Open-Label, Dose-Escalation Study to Evaluate Safety, Tolerability, and Clinical Activity of CBX-663 in Participants With Relapsed or Refractory Myeloid Malignancies, Advanced Solid Tumors, or Recurrent or Progressive Glioblastoma. CBX-663 | Not yet recruiting → Recruiting | Phase 1 | Crossbow Therapeutics, Inc. |
| Treatment of Olecranon Fractures in the Elderly Tension band wiring or plate fixation, Active non-operative treatment with optional plaster cast | Recruiting → Active not recruiting | Not applicable | Oslo University Hospital |
| 68Ga-NYM207 PET/CT Imaging in Hepatocellular Carcinoma 68Ga-NYM207 PET/CT | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | Peking Union Medical College Hospital |
| Study to Evaluate the Safety, Pharmacology and Efficacy of WIN378 in Adults With Moderate or Severe Asthma WIN378, Placebo | Active not recruiting → Recruiting | Phase 2 | Windward Bio |
| Real-time Symptom Monitoring Using ePROs to Prevent Adverse Events During Care Transitions ePRO Application | Recruiting → Terminated Grant Terminated by Sponsor | Phase 1 / Phase 2 | Brigham and Women's Hospital |
| A Study to Assess the Adverse Events and How Intravenously Infused Livmoniplimab in Combination With Budigalimab Moves Through the Bodies of Adult Chinese Participants With Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) Livmoniplimab, Budigalimab | Active not recruiting → Terminated Strategic considerations | Phase 1 | AbbVie |
| Electroacupuncture for Generalized Anxiety Disorder: Clinical Efficacy and Neuroimaging Mechanisms Electroacupuncture (EA), Sham Electroacupuncture (SEA), Medication | Not yet recruiting → Recruiting | Not applicable | Lishu Gao |
| Cervical Stiffness in Women With Threatened Preterm Labor Pregnolia System | Not yet recruiting → Recruiting | Pregnolia AG | |
| The FDR (Femoral Derotaton) Trail. Adolescent Lateral Entry Femoral Nail, Pediatric LCP Hip Plate System | Recruiting → Completed | Not applicable | Oslo University Hospital |
| Comparison of the Effect of Testosterone Administered for Micropenis Hypospadias Surgery With Bispectral Index Bispectral index (BIS) | Unknown → Completed | Namik Kemal University | |
| A Study of Single and Multiple Subcutaneous or Intravenous Doses of ADX-001 in Healthy Adults to Assess Safety, Effects, and Immune Response ADX-001, Placebo | Not yet recruiting → Recruiting | Phase 1 | Adaxion Therapeutics |
| Relationship Between Interoception and Postural Control in Constipation-Predominant Irritable Bowel Syndrome | Not yet recruiting → Recruiting | Saglik Bilimleri Universitesi | |
| Drug-drug Interaction Study of ZT002 Injection in Overweight and Obese Participants ZT002 injection, metformin, warfarin, ZT002 injection, rosuvastatin, digoxin | Recruiting → Active not recruiting | Phase 1 | Beijing QL Biopharmaceutical Co.,Ltd |
| Home Visitation Enhancing Linkages Project in Kansas e-SBI main session, e-SBI Booster Session, Text messaging | Not yet recruiting → Recruiting | Not applicable | The National Center on Addiction and Substance Abuse at Columbia University |
| Group-based Stabilization and Skill Training for Patients With Lasting Posttraumatic Reactions in Mental Health Care Group-based stabilization and skill training in addition to individual treatment, Treatment as usual | Recruiting → Active not recruiting | Not applicable | St. Olavs Hospital |
| A Study of Zovaglutide (ZT002 Injection) in Participants With Impaired Kidney Function and Healthy Participants Zovaglutide | Recruiting → Active not recruiting | Phase 1 | Beijing QL Biopharmaceutical Co.,Ltd |
| Autologous Serum Obtained by a Closed-Circuit Collection Device Autologous Serum 20% | Not yet recruiting → Active not recruiting | Phase 2 | GIANCARLO FATOBENE |
| NT-NOA - Novel Treatment of Some Men With Non-Obstructive Azoospermia Denosumab (Prolia), Letrozole (Aromatase Inhibitors) | Active not recruiting → Completed | Phase 1 / Phase 2 | Martin Blomberg Jensen |
| Dosimetry and Preliminary Clinical Application Study of a Novel Probe Targeting CD73 68Ga-dPNE, 18F-FDG | Recruiting → Completed | Early Phase 1 | First Affiliated Hospital of Fujian Medical University |
| Video Images About Decisions for Ethical Outcomes in the Emergency Department (VIDEO-ED) video decision aid, control arm ACP information sheet | Active not recruiting → Completed | Not applicable | Massachusetts General Hospital |
| China Treatment Trial for Tumor in Sellar Region With Unruptured Intracranial Aneurysm Tumor resection followed by aneurysm treatment, Aneurysm treatment followed by tumor resection, Observation | Not yet recruiting → Active not recruiting | Cheng sen | |
| A Study of SKB264 Versus Investigator's Choice Chemotherapy in Patients With Unresectable Recurrent or Metastatic Triple-Negative Breast Cancer SKB264, Paclitaxel, Nab-paclitaxel | Recruiting → Active not recruiting | Phase 3 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. |
| The Role of Mandala Painting Before Surgery Mandala | Recruiting → Completed | Not applicable | Niran Çoban |
| AI Telemedicine Support for Primary Care Physicians in El Salvador DoctorSV AI Assistant, Standard Telemedicine Workflow (No AI) | Not yet recruiting → Completed | Not applicable | Hospital El Salvador |
| Effect of Video -Based vs Standard ınformation on Maternal Anxiety and Procedure Decision in Pregnant Woman Offered Amniocentesis or Cvs Multilingual Video-Based Patient Education, Standard Verbal Informed Consent | Not yet recruiting → Recruiting | Not applicable | Ankara City Hospital Bilkent |
| A Study of a Weight Loss Intervention in People With Endometrial Cancer Tirzepatide | Recruiting → Active not recruiting | Early Phase 1 | Memorial Sloan Kettering Cancer Center |
| Cold Stored Whole Blood in Cardiothoracic Surgery Whole Blood transfusion | Unknown → Withdrawn Withdrawn because of recruitment and protocol issues. | Not applicable | Haukeland University Hospital |
| Malaria Molecular Surveillance in Mozambique (Phase 2) LDH-based malaria rapid diagnostic test, Malaria rapid diagnostic test | Recruiting → Active not recruiting | Centro de Investigacao em Saude de Manhica | |
| A Clinical Study to Compare Functional Outcomes After Surgery Using a Transverse or Longitudinal Surgical Incision in the Skin. Longitudinal incision, Transverse incision | Unknown → Recruiting | Not applicable | Corporacion Parc Tauli |
| Assessment of the Ocular Microbiome in Health and Disease Eye swab | Recruiting → Completed | Vanderbilt University Medical Center | |
| NIRS and BIS Monitoring During Cerebral Aneurysm Coiling Near-Infrared Spectroscopy (NIRS) and Bispectral Index (BIS) Monitoring | Not yet recruiting → Recruiting | Dokuz Eylul University | |
| Efficacy and Safety of Digital Therapeutics for Improving Shoulder Function After Rotator Cuff Repair digital therapeutics, usual care | Recruiting → Active not recruiting | Not applicable | Samsung Medical Center |
| Child's Behavior Using Single Rotary File System Versus Manual Instrumentation in Pulpectomy of Primary Molars Fanta AF F one rotary files 20 taper 4, Manual files (k files ,Mani, Inc., Japan). | Not yet recruiting → Recruiting | Not applicable | Cairo University |
| Norepinephrine With Ephedrine Versus Norepinephrine Alone During Spinal Anesthesia for Cesarean Delivery Ephedrine and Norepinephrine infusion, Norepinephrine infusion | Not yet recruiting → Recruiting | Phase 4 | Cairo University |
| Telerehabilitation Exercise Program for Postoperative Recovery in Lung Cancer. Therapeutic Exercise-Based Telerehabilitation, Usual Postoperative Care | Not yet recruiting → Recruiting | Not applicable | University of Seville |
| PEMF Therapy in Shoulder Tendinopathy Nanopulsed Electromagnetic Field Therapy (SIS), Balneophysiotherapy | Recruiting → Completed | Not applicable | Balnear and Rehabilitation Sanatorium Techirghiol |
| POCUS Screening for TAA in Hypertensive Patients in the ED Point-of-care ultrasound | Not yet recruiting → Completed | Chinese University of Hong Kong | |
| Electronic SBI(RT) for MSM in Argentina electronic screening and brief intervention., Phase 2: Assessment Only | Terminated → Completed | Not applicable | Florida State University |
| A Novel Aromatase Inhibitor, Leflutrozole, for Treatment of Non-Obstructive Azoospermia Leflutrozole, Dose 2 | Recruiting → Active not recruiting | Phase 1 / Phase 2 | Martin Blomberg Jensen |
| Short-term Effects of Osteopathic Manipulations on Heart Rate Variability in Lung Cancer Patients - A Randomized Pilot Study Osteopathic treatment, Quality of life assessment, Anxiety assessment | Not yet recruiting → Recruiting | Not applicable | Centre Hospitalier Henri Duffaut - Avignon |
| High-Power Short-Duration Radiofrequency Ablation in Patients With Typical Atrial Flutter Conventional cavotricuspid isthmus ablation, High-power short-duration ablation | Unknown → Completed | Not applicable | Jose Luis Ibañez Criado |
| A Study Comparing the Effect and Safety of Linaprazan Glurate to Lansoprazole in Participants With Erosive Esophagitis (EE) Due to Gastroesophageal Reflux Disease (GERD) Linaprazan glurate 50 mg Twice Daily (BID), Linaprazan Glurate 50 mg Once Daily (QD), Lansoprazole 30 mg Once Daily (QD) | Active not recruiting → Completed | Phase 3 | Cinclus Pharma Holding AB |
| Clinical Evaluation of a Novel Trifocal IOL LPYWT0, PXYWT0, Cataract Surgery | Not yet recruiting → Recruiting | Not applicable | Alcon Research |
| Electronic Quitline Referral With Enhanced Academic Detailing for the Promotion of Smoking Cessation Enhanced Academic Detailing, Informational Intervention | Active not recruiting → Completed | Not applicable | OHSU Knight Cancer Institute |
| Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study | Recruiting → Completed | Brigham and Women's Hospital | |
| PREMEDICAL is a Clinical Investigation Aiming to Create a Data Basis That Can be Used to Enrich Information Collected in the Course of the Classic Patient Journey. Patients in the Emergency Department Will be Asked to Answer Patient-related and Symptom-oriented Questions. Minimum Age is 18 Years | Recruiting → Terminated Funding issues, recruitment targets not met | XUND Solutions GmbH | |
| Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Sickle Cell Disease autologous bone marrow derived CD34+ HSPCs electroporated with BCL11A enhancer targeting Cas9 ribonucleoprotein, Sequencing Assay for Variant rs114518452 | Not yet recruiting → Recruiting | Phase 1 | Daniel Bauer |
| Pharmacist-Led Treat-to-Target Urate Lowering Therapy in Patients With Gout Pharmacist-Led | Not yet recruiting → Recruiting | Not applicable | VA Office of Research and Development |
| Efficacy and Safety of Myopic Macular Hole Closure Surgery Without Endotamponade Agent ILM flap with no endotamponade technique | Active not recruiting → Completed | Not applicable | Chinese University of Hong Kong |
| A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease VHB937, Placebo | Recruiting → Active not recruiting | Phase 2 | Novartis Pharmaceuticals |
| Pharmacokinetics of Apixaban in Peritoneal Dialysis Apixaban | Unknown → Completed | Chinese University of Hong Kong | |
| Efficacy of a Vented Liner and Socket System for Individuals With Trans-femoral Amputation Vented suspension system, Non-vented suspension system | Withheld → Completed | Not applicable | Jóna Valgerður Kristjánsdóttir |
| RESOLUTE ONYX China Single Arm Study Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System | Active not recruiting → Completed | Not applicable | Medtronic Vascular |
| MediPD: An Online Mediterranean Diet Program for People Living With Parkinson's Disease MediPD Online Mediterranean Diet Program | Not yet recruiting → Recruiting | Not applicable | Queen's University, Belfast |
| Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers | Active not recruiting → Completed | National Institute of Mental Health (NIMH) | |
| Acceptance and Commitment Therapy for Depressed People With Spinal Cord Injuries Acceptance and commitment therapy (ACT) | Active not recruiting → Completed | Not applicable | University of South Florida |
| Effects of Clinical Pilates on Pain and Quality of Life in Women With Dyspareunia Clinical Pilates Exercise | Not yet recruiting → Completed | Not applicable | Okan University |
| Scheduled or as Needed Pain Regimen? Motrin and narcotic | Recruiting → Active not recruiting | Phase 4 | Cape Fear Valley Health System |
| Trial for Surgical Treatment of Reducible Atlantoaxial Dislocation Intra-articular Cages | Unknown → Recruiting | Not applicable | Xuanwu Hospital, Beijing |
| Assessment of Physical Performance in Children | Active not recruiting → Completed | Afyonkarahisar Health Sciences University | |
| Effect Of Brain Gym Exercises On Balance And Quality Of Life In Children With Spastic Diplegia Brain gym exercises, Conventional physical therapy program | Recruiting → Completed | Not applicable | Cairo University |
| BHV-7000 Responsive Neurostimulation System (RNS) Study BHV-700 | Active not recruiting → Completed | Phase 1 | Yale University |
| An Open-label DDI Study to Investigate the Effect of Rilzabrutinib on P-gp, BCRP, OATP1B1 and OATP1B3 Inhibition Rilzabrutinib, Rosuvastatin, Digoxin | Recruiting → Active not recruiting | Phase 1 | Sanofi |
| Rise & Thrive: Community-Engagement Intervention for Stress and Depression in Youth. Rise Together: Community Engagement Intervention, Adulting 101: Life Skills | Not yet recruiting → Recruiting | Not applicable | Ann & Robert H Lurie Children's Hospital of Chicago |
| Helpline Pilot Factorial Trial Standard Helpline (SH), Motivational Interviewing (MI), Coping Skills Training (CST) | Not yet recruiting → Recruiting | Not applicable | The National Center on Addiction and Substance Abuse at Columbia University |
| Arterial Stiffness and Endothelial Function in Heart Failure Study Assessment | Not yet recruiting → Recruiting | Coventry University | |
| Factors Associated With Occluding the Upper Esophagus by Paratracheal Force | Unknown → Completed | SMG-SNU Boramae Medical Center | |
| Efficacy of PErioperative PEmbrolizumab Treatment in Patients With Resectable Metastases From Kidney Cancer Pembrolizumab injection plus metastasis directed treatment (surgery or RT), Tumor resection or RT | Unknown → Active not recruiting | Phase 2 | Consorzio Oncotech |
| Pulmonary Hypertension (PH) Biorepository for Translational Research | Not yet recruiting → Recruiting | National Institutes of Health Clinical Center (CC) | |
| The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients With Opioid Use Disorder Seen In Primary Care MOUD "Plus" Intervention (treatment as usual + coordinated counseling and referral to community based peer), Treatment As Usual (primary care with low threshold MOUD prescribing) | Recruiting → Active not recruiting | Not applicable | Oregon Health and Science University |
| Digital Lifestyle Intervention for Lung Cancer Survivors Lifestyle | Recruiting → Completed | Not applicable | Kai-Uwe Schmitt, PhD, MEng, ICID |
| Serum Neurofilament-light Chain and GFAP Levels in Patients From the OFSEP Cohort at Different Landmarks of Multiple Sclerosis Blood sample | Recruiting → Active not recruiting | Centre Hospitalier Universitaire de Nīmes | |
| A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Recurrent or Metastatic Urothelial Carcinoma(PANKU-Bladder01) BL-B01D1, Docetaxel or Paclitaxel | Recruiting → Active not recruiting | Phase 3 | Sichuan Baili Pharmaceutical Co., Ltd. |
| This Study Evaluates the Impact of the Sodium Management Tool (SMT) on Hemodialysis Patient Outcomes Compared to Standard Care dialysis assisted with the sodium management tool | Not yet recruiting → Completed | Not applicable | Luzerner Kantonsspital |
| Daunorubicin, Cytarabine, and Midostaurin in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia cytarabine, daunorubicin, midostaurin | Unknown → Completed | Phase 3 | Alliance for Clinical Trials in Oncology |
| A Phase III, Multicentre Study to Evaluate Consolidation Treatment With AZD0120 Compared With ASCT, in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible (DURGA-6). AZD0120, Cyclophosphamide, Fludarabine | Not yet recruiting → Recruiting | Phase 3 | AstraZeneca |
| The Patient and Family Centered I-PASS LISTEN Study: Language, Inclusion, Safety, and Teamwork for Equity Now PFC I-PASS Intervention, PFC I-PASS+ Intervention | Recruiting → Active not recruiting | Not applicable | Boston Children's Hospital |
| Comparison of the Breast Tumor Microenvironment Breast tissue collection, Blood sample collection | Active not recruiting → Completed | Columbia University | |
| CITE: Clinical Inference Tethered to Evidence - a Retrieve-and-verify Layer for AI Care Plans CITE evidence-grounding retrieve-and-verify layer, AI care plan with safety guardrails | Not yet recruiting → Completed | Not applicable | Waymark |
| Cervical Spinal Cord Signal Abnormalities in Patients With Cervical Radicular Pain Clinical and Cervical MRI Assessment | Not yet recruiting → Recruiting | Ankara City Hospital Bilkent | |
| Preoperative Sleep Quality and Postoperative Outcomes in Breast Surgery Preoperative Sleep Quality Assessment (PSQI) | Recruiting → Completed | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital | |
| A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Robotic Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS Trial Neuronavigated robotic-enabled TMS, NRX-101, Sham TMS | Not yet recruiting → Recruiting | Phase 2 / Phase 3 | NeuroRx, Inc. |
| Bronchoscopic Airway Clearance for Improving Lung Aeration in Mechanically Ventilated Patients With Atelectasis Flexible Bronchoscopy-Guided Airway Clearance, Usual Airway Care | Not yet recruiting → Recruiting | Not applicable | Southeast University, China |
| The European Robotic Spinal Instrumentation (EUROSPIN) Study Transpedicular Instrumentation | Active not recruiting → Completed | Marc Schröder | |
| A Study to Evaluate the Long-term Safety and Efficacy of Lunsekimig in Adult Participants With Chronic Obstructive Pulmonary Disease (COPD) Lunsekimig | Recruiting → Enrolling by invitation | Phase 3 | Sanofi |
| China Glomerulonephritis Kidney Transplant Recipient Cohort: A Prospective Multicenter Observational Study | Not yet recruiting → Recruiting | AstraZeneca | |
| Navigation Interventions for Patients With Breast Cancer and High-risk Social Determinants of Health Patient navigator | Not yet recruiting → Recruiting | Not applicable | Washington University School of Medicine |
| Automating Tobacco Cessation in Primary Care Tobacco counseling resources | Not yet recruiting → Recruiting | Not applicable | University of Pennsylvania |
| Feasibility and Effects of Noninvasive Brain Stimulation on Pain Perception in People With Fibromyalgia Primary Motor Cortex Stimulation, Occipital Lobe Stimulation | Not yet recruiting → Recruiting | Not applicable | Pulkit Grover |
| Contribution of 7 Tesla MRI of the Hypothalamus in the Diagnosis of Type 1 Narcolepsy 7T MRI | Unknown → Completed | Not applicable | Assistance Publique Hopitaux De Marseille |
| Improving Maternal Nutrition in Matlab In-home, intensive nutrition counseling | Unknown → Completed | Not applicable | International Centre for Diarrhoeal Disease Research, Bangladesh |
| Dose Low Dose Ketamine in Casesarian Application of ketamine and midazolam or ketamine alone to patients undergoing cesarean section under spinal anesthesia | Unknown → Completed | Inonu University | |
| Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Transcatheter Aortic Valve Implantation Patients No preoperative dental screening | Unknown → Recruiting | Odense University Hospital | |
| IV-X Medical First-in-Human Peripheral Intravascular Lithotripsy Study for PAD IV-X Medical IVL System | Not yet recruiting → Active not recruiting | Not applicable | IVX Medical |
| Turkish Validity and Reliability of the Behavioral Indicators of Pain Scale(ESCID) The ESCID scale | Recruiting → Completed | Not applicable | Saglik Bilimleri Universitesi |
| RCT of Combination Effect of Vibration Treatment and HMB Supplementation on Myosteatosis and NMJ Degeneration Low-magnitude High-frequency Vibration, β-hydroxy β-methylbutyrate (HMB) supplement, Protein supplement | Recruiting → Completed | Not applicable | Chinese University of Hong Kong |
| CareCOPD - COPD Home Monitoring Study CareCOPD Platform | Unknown → Active not recruiting | Cognita Labs LLC | |
| Oxygen Toxicity: Mechanisms in Humans Sleep Deprivation, Caffeine, Methylphenidate | Suspended → Recruiting | Not applicable | Duke University |
| Trial in Healthy Volunteers to Evaluate 150 mg Subcutaneous CIT-013 CIT-013 high dose, Placebo | Not yet recruiting → Completed | Phase 1 | Citryll BV |
| Optimizing the Follow-Up Journey in Interstitial Lung Disease: The OPTIMIZE-ILD-2 Trial Standard ILD Follow-Up Pathway, Optimized One-Day ILD Follow-Up Circuit | Recruiting → Active not recruiting | Not applicable | Hospital de Granollers |
| Refugee Mental Health and Wellness Pilot Study Wellbeing Program | Unknown → Withdrawn Investigator has left UCLA and the study is closed without enrollment | Not applicable | University of California, Los Angeles |
| SIM0718 Treatment of Asthma Clinical Study SIM0718 injection, SIM0718 injection of placebo | Recruiting → Active not recruiting | Phase 3 | Simcere Pharmaceutical Co., Ltd |
| Evaluation of Metformin Effect on the Fertility of Women Treated With 131I for Thyroid Cancer metformin, Radioactive iodine (I-131) | Unknown → Recruiting | Phase 3 | Medical University of Bialystok |
| Whole-Body Vibration in Patients With Patellofemoral Pain Syndrome Whole body vibration, Sham Whole Body Vibration | Not yet recruiting → Completed | Not applicable | Pamukkale University |
| Evaluation of the Effect of Adding Sodium Bicarbonate to Lidocaine in the Treatment of Myofascial Pain Syndrome Lidocaine 2 %, Lidocaine + Sodium Bicarbonate | Not yet recruiting → Recruiting | Not applicable | Cairo University |
| Antimicrobial Photodynamic Therapy With ICG-Loaded Nanoparticles for Periodontitis Management Non- surgical periodontal therapy followed by photodynamic therapy with ICG-loaded nanoparticles, Non- surgical periodontal therapy followed by photodynamic therapy with ICG-loaded macroparticles, Non- surgical periodontal therapy only | Recruiting → Completed | Phase 2 | Nada Mahmoud Soliman |
| A Pilot Study to Evidence Improved Cranial Flap Fixation With a Bioresorbable Bone Adhesive Tetranite for Cranial Flap Fixation (TN-CFF) | Active not recruiting → Completed | Not applicable | RevBio |
| Palmitoylethanolamide vs Ibuprofen for Pain After ESWL Palmitoylethanolamide (PEA), Ibuprofen (Brufen®) | Not yet recruiting → Completed | Not applicable | Benha University |
| Evaluation of the Efficacy and Safety of Befotertinib Combined With Bevacizumab as First-Line Treatment for EGFR-Positive Non-Small Cell Lung Cancer With Brain Metastases: A Single-Arm, Open-Label, Prospective Phase II Clinical Study The treatment regimen is Befotertinib combined with Bevacizumab. | Recruiting → Active not recruiting | Phase 2 | Li-kun Chen |
| Investigating Baby Behavior and Family Technology Use Study Technology Use during Feeding Conditions | Recruiting → Active not recruiting | Not applicable | California Polytechnic State University-San Luis Obispo |
| Clinical Study Evaluating the Anticancer Effect of Pentoxiphylline in Patients With Metastatic Colorectal Cancer Pentoxifylline, FOLFOX, XELOX | Unknown → Completed | Phase 4 | Tanta University |
| Healthy Lifetime - Phase 2 Nurse-led health coaching | Recruiting → Completed | Not applicable | University of Michigan |
| BEhavioral and Adherence Model for Improving Quality, Health Outcomes and Cost-Effectiveness of healthcaRe B-COMPASS implementation | Recruiting → Completed | Not applicable | Technical University of Madrid |
| Combined Effect of Biofeedback and Scapular Stabilization Exercises in Children With Swimmer's Shoulder Designed scapular stabilization using pressure biofeedback, Designed physical therapy program | Not yet recruiting → Completed | Not applicable | Cairo University |
| CAMELLIA Cohort: A Longitudinal Study to Understand Sexual Health and Prevention Among Women in Alabama Camelia Cohort | Enrolling by invitation → Active not recruiting | Not applicable | University of Alabama at Birmingham |
| CT-Based Scoring System to Predict Surgical Need in Tracheal Stenosis (TSMAS Study) CT-Based Morphologic and Attenuation Scoring | Not yet recruiting → Completed | Ondokuz Mayıs University | |
| Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People Virtual Reality Tool | Recruiting → Active not recruiting | Not applicable | Medical University of South Carolina |
| Hemoglobin Levels for Blood Transfusions During and After Surgery Restrictive Transfusion, Liberal transfusion | Recruiting → Active not recruiting | Not applicable | Ottawa Hospital Research Institute |
| The Effects of Claudication Severity on Functional Outcomes Pain Free Exercise (PF), Moderate Claudication Pain Exercise (MOD-P), Maximal Claudication Pain Exercise (MAX-P) | Unknown → Completed | Not applicable | University of Central Lancashire |
| Chewing Gum and Cold Gargle on Post-Bronchoscopy Symptoms Chewing Gum, Cold Water Gargle | Recruiting → Completed | Not applicable | Ankara University |
| MIECC vs Conventional Cardiopulmonary Bypass and Systemic Inflammation in CABG Minimally Invasive Extracorporeal Circulation, Conventional Cardiopulmonary Bypass | Active not recruiting → Completed | Bursa Yuksek Ihtisas Training and Research Hospital | |
| First in Human Study of YB1-X7 Injection YB1-X7 Injection (IT), YB1-X7 Injection (IV), PD-1 inhibitor | Not yet recruiting → Recruiting | Not applicable | Shanghai Salvectors Biotechnology LTD. |
| A Preliminary Clinical Study on the Efficacy of Cyclophosphamide and Sirolimus Combined With VIC-1911 in Preventing Graft-versus-Host Disease After Haploidentical Stem Cell Transplantation in Children 1mg /kg VIC-1911 | Not yet recruiting → Recruiting | Phase 1 | Shanghai Jiao Tong University School of Medicine |
| Add-on Therapy With Low Dose Fenfluramine in Lennox Gastaut Epilepsy Fenfluramine | Unknown → Completed | Phase 2 | KU Leuven |
| When to INDuce for OverWeight? (WINDOW) Elective induction of labor at 39 gestational weeks and 0 to 3 days | Recruiting → Completed | Not applicable | University of Aarhus |
| Capillary Leak Index Versus Conventional Biomarkers in Predicting Sepsis-Related Outcomes Capillary Leak Index Versus | Recruiting → Completed | Benha University | |
| Validity and Reliability of 6 Minute Stepper Test in Kidney Transplant Recipients | Recruiting → Completed | Hacettepe University | |
| Effect of Opioid-free Anesthesia on Sleep Quality, Cognitive Function and Recovery Quality After General Anesthesia in Elderly Patients Opioid-free Analgesics, Opioid group | Unknown → Not yet recruiting | Not applicable | Beijing Friendship Hospital |
| Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease Anti-TNF therapy | Recruiting → Active not recruiting | Phase 4 | Connecticut Children's Medical Center |
| Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease Physiology-guided NCL PCI, Angiography-guided NCL PCI | Recruiting → Active not recruiting | Not applicable | Population Health Research Institute |
| Evaluation of the Predictors of Clinical and Radiological Response to Gamma-Knife Radiosurgery in the Treatment of Intermediate Ventral Nucleus of the Thalamus (VIM) Thalamotomy Tremor. gamma knife radiosurgery | Unknown → Completed | Assistance Publique Hopitaux De Marseille | |
| Promoting Active Living Among People With Advanced Cancer Acceptance- and mindfulness-based physical activity promotion | Active not recruiting → Completed | Not applicable | University of Oklahoma |
| Effect of Serotonergic Stimulation on the Gut-brain Axis serotonergic stimulation, no serotonergic stimulation | Active not recruiting → Completed | Not applicable | Örebro University, Sweden |
| Critical Appraisals at Play Competition based Education Format | Enrolling by invitation → Completed | Not applicable | Community Medical Center, Toms River, NJ |
| Advancing Clinical Heart Failure Outcomes Leveraging Defibrillation Lead Implant System for Left Bundle Branch Area Pacing LBBAP Therapy, LOT-CRT, ICD | Not yet recruiting → Recruiting | Not applicable | Medtronic Cardiac Rhythm and Heart Failure |
| Acceptability and Feasibility of an In-person 8-week Mindfulness-Based Cognitive Therapy Program Among Undergraduates Mindfulness in Students | Recruiting → Completed | Not applicable | Universidad de los Andes, Chile |
| Acceptability and Feasibility of a Universal Preventive Intervention "Universal preventive intervention for depression and anxiety for university students" | Unknown → Completed | Not applicable | Universidad de los Andes, Chile |
| The GRoceries Aimed at Increasing Nutrition Study Marketing Nudges Only, Marketing Nudges + Dynamically Adapted Financial Incentives | Recruiting → Active not recruiting | Not applicable | University of Pennsylvania |
| A Digital Twin for Exoskeleton Pilot A Digital Twin for Exoskeleton Pilot | Recruiting → Completed | Not applicable | National Taiwan University Hospital |
| Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer Trifluridine/tipiracil, Oxaliplatin | Recruiting → Suspended Interim Analysis | Phase 2 | Case Comprehensive Cancer Center |
| Residual Gastric Content and GLP-1 | Recruiting → Terminated The study was Terminated by primary investigator | University of Arkansas | |
| Post-marketing Surveillance Study for the Safety of Efluelda® Pre-filled Syringe Efluelda® Pre-filled syringe | Not yet recruiting → Recruiting | Sanofi | |
| Atezolizumab, Guadecitabine, and CDX-1401 Vaccine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Atezolizumab, DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Guadecitabine | Completed → Terminated The study was terminated due to a shortage of the drug supply. | Phase 1 / Phase 2 | National Cancer Institute (NCI) |
| Clinical Utility of Residual Hearing in the Cochlear Implant Ear Electrocochleography | Recruiting → Active not recruiting | Not applicable | Ohio State University |
| HILT vs ESWT in Supraspinatus Tendinitis High-Intensity Laser Therapy, Extracorporeal Shock Wave Therapy, Conventional Physical Therapy | Not yet recruiting → Recruiting | Not applicable | Kafrelsheikh University |
| A Pragmatic Trial With Optimized Dose of Rifampicin and Moxifloxacin for the Treatment of Drug Susceptible Pulmonary Tuberculosis Optimised rifamycin | Unknown → Completed | Phase 3 | Stellah Mpagama |
| Assessment of a Robotic Distal Gastrectomy on Non-inferiority of N2 Area Nodal Dissection Distal Gastrectomy with D2 LND | Unknown → Completed | Phase 2 | National Cancer Center, Korea |
| Testing the Youth Physical Activity Promotion Model (YPAP) in Brazilian Adolescents | Not yet recruiting → Active not recruiting | Hospital Universitario Pedro Ernesto | |
| A Study to Investigate Pharmacokinetics (PK), Safety, and Tolerability of VH4367310 in Healthy Adult Participants VH4367310, Placebo | Not yet recruiting → Recruiting | Phase 1 | ViiV Healthcare |
| Effects of Magnesium L-Threonate on Sleep, Recovery, and Athletic Performance in Collegiate Athletes Magnesium L-Threonate, Placebo | Active not recruiting → Completed | Not applicable | University of California, Los Angeles |
| HOme PElvic Floor Improvement Trainer Trial Home Pelvic Floor Trainer | Not yet recruiting → Recruiting | Not applicable | University of Colorado, Denver |
| Can Dapagliflozin Preserve Structure and Function in Transplanted Kidneys? Dapagliflozin 10mg Tab, Placebo | Recruiting → Active not recruiting | Phase 4 | Oslo University Hospital |
| A Study to Evaluate Single-dose of HB0056 in Healthy Adult Participants HB0056, Placebo | Recruiting → Completed | Phase 1 | Shanghai Huaota Biopharmaceutical Co., Ltd. |
| Pembrolizumab in the Treatment of Advanced, Progressive Adrenocortical Carcinoma. Pembrolizumab 25 MG/ML [Keytruda] | Recruiting → Active not recruiting | Phase 2 | Maria Sklodowska-Curie National Research Institute of Oncology |
| Efficacy and Safety of Baricitinib in the Post-intracerebral Hemorrhage Pulmonary Injury Baricitinib | Unknown → Active not recruiting | Phase 1 / Phase 2 | Tianjin Medical University General Hospital |
| Real-World Outcomes of Drug-Coated Balloon Angioplasty in Coronary Artery Disease Coronary Drug-Coated Balloon | Not yet recruiting → Recruiting | Kristian Rivera | |
| Feasibility Study Comparing One vs Two Probes for Thermal Ablation Among Cervical Cancer Screen Positive WLWH in C1001P-CS9 South Africa Thermal ablation (TA) with 1 probe, Thermal ablation (TA) with 2 probes | Not yet recruiting → Recruiting | Not applicable | Fred Hutchinson Cancer Center |
| Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Sinusitis) Amoxicillin, Amoxi Clavulanate, Amoxicillin Placebo | Not yet recruiting → Recruiting | Phase 4 | Nader Shaikh |
| A Phase I Study of VC005 Tablets in Adolescent Subjects With Severe Alopecia Areata VC005 tablets | Not yet recruiting → Recruiting | Phase 1 | Jiangsu vcare pharmaceutical technology co., LTD |
| FlexWave Trial: Efficacy of Extracorporeal Shock Wave Therapy in Post-Stroke Upper Limb Spasticity focused extracorporeal shock wave therapy (ESWT) | Recruiting → Active not recruiting | Not applicable | National Taiwan University Hospital |
| Exosomal microRNAs as a Biomarker in Panic Disorder and in Response to CBT CBT- both internet and face to face, No intervention | Unknown → Completed | Not applicable | Hebrew University of Jerusalem |
| Single-Sided Deafness and Asymmetric Hearing Loss MED-EL Cochlear Implant System | Recruiting → Active not recruiting | Not applicable | Med-El Corporation |
| Intravenous N-acetylcysteine and Oseltamivir Versus Oseltamivir in Adults Hospitalized With Influenza and Pneumonia N-acetyl cysteine, 5% Dextrose | Unknown → Recruiting | Phase 3 | Chinese University of Hong Kong |
| Identifying Individuals at Risk of Glucocorticoid-Induced Impairment of Bone Disease Prednisolone, Placebo | Active not recruiting → Completed | Phase 2 | Odense University Hospital |
| ExAblate Transcranial MRgFUS for Unilateral Pallidotomy for the Treatment of Parkinson's Disease Transcranial ExAblate | Active not recruiting → Completed | Not applicable | InSightec |
| Evaluation of the Safety and Efficacy of a Full-Body Electrostimulation Garment for Individuals With Neurological and Neuromuscular Conditions That Cause Spasticity, Hyperreflexia, and Pain Active full-body stimulation, Sham full-body stimulation | Recruiting → Active not recruiting | Not applicable | Shirley Ryan AbilityLab |
| Mineral-Infused Clothing for Recovery From Muscle Soreness and Muscle Damage After Exercise Mineral-infused garment, Non-infused control garment, Muscle-damaging eccentric exercise (drop jumps) | Not yet recruiting → Recruiting | Not applicable | StudySetGo |
| Clinical Study to Evaluate Remineralization Using an in Situ Model. Fluoride toothpaste containing 750 ppm MFP in a Dical base, Fluoride toothpaste containing 1450 ppm MFP in a Dical base, Fluoride-free toothpaste in a Dical base | Not yet recruiting → Enrolling by invitation | Phase 3 | Colgate Palmolive |
| Leveraging Interventions for Caregiver Growth, Health, Training, Empowerment and Navigation: Comparing Group Behavioral Interventions to Improve Dementia Caregiver Strain Caring Together, Savvy Caregiver | Not yet recruiting → Recruiting | Not applicable | Massachusetts General Hospital |
| The Digestion of Protein Powders in Healthy Participants Using SIMBA and LIMBA Capsule Milk Protein Concentrate, Micellar Casein Isolate | Active not recruiting → Completed | Not applicable | Nimble Science Ltd. |
| Treatment of a Single Patient With CRD-TMH-001 CRD-TMH-001 | Unknown → Completed | Phase 1 | Cure Rare Disease, Inc |
| Decentralization of Hepatitis B Care in Sub-Saharan Africa: a Pilot Program in Ethiopia Tenofovir Disoproxil Fumarate | Recruiting → Active not recruiting | Oslo University Hospital | |
| Framework for Optimizing, Refining, and Unifying Management of HSCT in Pediatric ALL Total Body Irradiation 8 Gy, Ruxolitinib, Blinatumomab | Not yet recruiting → Recruiting | Phase 2 / Phase 3 | Bambino Gesù Hospital and Research Institute |
| Inpatient Stroke Recovery Using Sensors Wearable sensors | Recruiting → Enrolling by invitation | Shirley Ryan AbilityLab | |
| SMART GOALS for Youth With Prediabetes SMART GOALS Setting Tool/ Protocol | Unknown → Recruiting | Not applicable | Northwell Health |
| Autus Valve Continued Access Study (CAS) Pulmonary Valve Replacement Surgery | Recruiting → Active not recruiting | Not applicable | Edwards Lifesciences |
| Motor Control Retraining Exercises on Shoulder Dysfunction Post Mastectomy motor control retraining exercises, traditional physical therapy for shoulder dysfunction | Recruiting → Completed | Not applicable | Cairo University |
| An Exploratory Study to Evaluate Skin Brightening Effects of Different Cosmetic Formulations on UV Irradiated Tanning Model SMR 1, SMR 2, SMR 3 | Not yet recruiting → Active not recruiting | Not applicable | Unilever R&D |
| A Trial of the Safety and Tolerability of SEP-363856 in Adults With Generalized Anxiety Disorder SEP-363856 | Not yet recruiting → Recruiting | Phase 3 | Otsuka Pharmaceutical Development & Commercialization, Inc. |
| The Efficacy of Non-invasive Brain Stimulation (NIBS) on Cognitive Functions in Patients With Chronic Obstructive Pulmonary Disease (COPD) Non-invasive brain stimulation, Sham Non-Invasive brain stimulation | Not yet recruiting → Active not recruiting | Not applicable | Ministry of Health, Kuwait |
| Combing a Deep Learning-Based Radiomics With Liquid Biopsy for Preoperative and Non-invasive Diagnosis of Glioma Prediction of glioma grading and molecular subtype | Unknown → Completed | Second Affiliated Hospital of Nanchang University | |
| COordiNated CommuNication, Education, and Care Transitions After Acute Kidney Injury (CONNECT-AKI) AKI Discharge Summary Template, Chat-Based Educational Messaging Program | Not yet recruiting → Recruiting | Not applicable | Northwell Health |
| The Mobile Health and Wellness Program Remote Health Study Remote patient monitoring, Telephone | Enrolling by invitation → Completed | Not applicable | Virginia Commonwealth University |
| Extensively Hydrolyzed Formula Growth Monitioring Study (GMS) Extensively hydrolyzed casein formula (C-eHCF), commercially available, Extensively hydrolyzed casein formula (INV-eHCF) | Not yet recruiting → Recruiting | Not applicable | Mead Johnson Nutrition |
| Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis Nemolizumab | Active not recruiting → Completed | Phase 3 | Galderma R&D |
| Histotripsy in Biliary Tract Cancer Gemcitabine, Cisplatin, Durvalumab | Not yet recruiting → Recruiting | Not applicable | NYU Langone Health |
| MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors LY3962673, Cetuximab, Gemcitabine | Recruiting → Active not recruiting | Phase 1 | Eli Lilly and Company |
| Phase 1 Single Ascending Doses (SAD) of M5542 in Healthy Participants M5542, Placebo | Recruiting → Suspended The study is currently paused pending a potential amendment. | Phase 1 | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany |
| Cardiometabolic Effects of Non-Nutritive Sweeteners (NNS) in Type 1 Diabetes (T1D) Cherry Sports Drink | Not yet recruiting → Recruiting | Not applicable | Medical College of Wisconsin |
| A Study of ImmunoPet Imaging Using 89Zr-DFO-REGN5054 in Adult Participants With Solid Cancers Treated With Cemiplimab 89Zr˗DFO˗REGN5054, cemiplimab | Recruiting → Active not recruiting | Phase 1 | Regeneron Pharmaceuticals |
| Rituximab for Treatment of Checkpoint Inhibitor Induced Immune-related Adverse Events Rituximab (RTX) | Not yet recruiting → Recruiting | Phase 1 | Inge Marie Svane |
| Clinical Investigation of Oral Malodor for Max Fresh Toothpaste Containing Zinc Citrate Versus a Commercially Available Regular Fluoride Toothpaste Max Fresh Toothpaste, Colgate Cavity Protection Toothpaste | Active not recruiting → Completed | Phase 3 | Colgate Palmolive |
| Add-on Clioquinol in Drug-resistant Childhood Epilepsy: an Exploratory Study Clioquinol | Unknown → Completed | Phase 2 | KU Leuven |
| Exploratory Clinical Research for the Evaluation of Human GMP (Good Manufacturing Practice) Collagen Implants (Humabiologics) in the Treatment of Corneal Melting (RCJ-COL3D-MC-01-2026) 3D collagen implant printed under GMP conditions. | Not yet recruiting → Recruiting | Not applicable | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal |
| 8-Chloroadenosine in Combination With Venetoclax for the Treatment of Patients With Relapsed/Refractory Acute Myeloid Leukemia 8-Chloroadenosine, Venetoclax | Recruiting → Suspended Safety Issues, status is being updated per PI due to safety issues. Study is now Temporarily Closed to Accrual. | Phase 1 | City of Hope Medical Center |
| Feasibility of Integrating Olfactory Stimuli Into Virtual Reality Cue Exposure for Patients With Alcohol Dependence VR Cue-Exposure Including Olfactory Stimuli | Recruiting → Completed | Not applicable | Charite University, Berlin, Germany |
| A Study to Learn About the Single Dose Pharmacokinetics of Study Medicine Called Tilrekimig in Healthy Adults When Co-Mixed With rHuPH20 tilrekimig and rHuPH20 | Recruiting → Active not recruiting | Phase 1 | Pfizer |
| Intraoperative Monitoring to Predict Postoperative Complications After Thyroidectomy | Recruiting → Completed | Central Hospital, Nancy, France | |
| Clinical Trial of TQB3126 for Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy in Breast Cancer Subjects TQB3126 | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
| Validation of Insulin Dose Prediction Model Based on Artificial Intelligence Algorithm CSII in the prediction model group, CSII in the empirical group | Recruiting → Terminated Recruitment was stopped early because hospital length-of-stay constraints limited protocol delivery. The PI's decision also took account of the available non-inferiority results. | Not applicable | Sun Yat-sen University |
| Acceptability and Feasibility of Reframe-IT+U for Suicidality in University Students. Indicated Prevention for suicidality | Not yet recruiting → Completed | Not applicable | Universidad de los Andes, Chile |
| Enhancing Referral Decision-making for Advanced Treatment in Parkinson's Disease Through Objective Measurements and Patient Reported Outcomes. Neptune, Standard clinical care | Unknown → Active not recruiting | Not applicable | Copenhagen University Hospital, Rigshospitalet |
| The Study to Evaluate the Plaque Control and Anti-Gingivitis Efficacy of a Toothpaste in Chinese Population Test Toothpaste, Regular Fluoride Toothpaste | Not yet recruiting → Recruiting | Not applicable | HALEON |
| A Randomised Control Clinical Trial Investigating the Effect of H-PRF on Implant Stability and Marginal Bone Levels Horizontal platelet-rich fibrin (H-PRF) | Unknown → Completed | Not applicable | University of Dublin, Trinity College |
| Comparison of Kinesio Taping Techniques in Ulnar Nerve Entrapment Kinesio Taping with Space-Correction Technique, Kinesio Taping with Neural Technique, Sham/Placebo Taping | Not yet recruiting → Recruiting | Not applicable | Antalya Training and Research Hospital |
| Assessment of Biomarkers in Patients With Decompensated Heart Failure and Underlying Coronary Artery Disease Biomarker Assessment | Unknown → Completed | CirQuest Labs, LLC | |
| Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain SL1002, Normal Saline | Recruiting → Active not recruiting | Phase 3 | Saol Therapeutics Inc |
| Mediators of Loin Pain in IgA Nephropathy | Not yet recruiting → Enrolling by invitation | University of Leicester | |
| Anti-VEGF Therapy for Acute Thyroid Eye Disease Sub-tenon injection of saline followed by a sub-tenon injection of aflibercept, Sub-tenon injection of hyaluronidase (HA) followed by a sub-tenon injection of aflibercept, Sub-tenon injection of hyaluronidase (HA) alone | Completed → Terminated Funding prematurely ended | Phase 2 | Massachusetts Eye and Ear Infirmary |
| Whole Body HER2 Quantification With 89Zr-Trastuzumab PET/CT to Asses Zr-trastuzumab Accumulation in HER2-mutated and HER2-overexpressing Metastatic Non-small Cell Lung Cancer PET imaging with ⁸⁹Zr-trastuzumab, Blood sampling for pharmacokinetics | Not yet recruiting → Recruiting | Phase 1 | The Netherlands Cancer Institute |
| Contingency Management to Improve Medication for Opioid Use Disorder Continuation After the Emergency Department Contingency Management, Usual care as prescribed by the ED physicians | Recruiting → Completed | Not applicable | University of Vermont |
| Improving HPV Vaccination Coverage Among Adolescent Girls in Mali and Côte d'Ivoire Through Community Health Worker Follow-up HPV vaccination pro-active community-based follow-up model, Standard community mobilization | Active not recruiting → Completed | Not applicable | Arsène Brunelle Sandie |
| Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Otitis Media) Amoxicillin, Amoxicillin-Clavulanate, Amoxicillin Placebo | Not yet recruiting → Recruiting | Phase 4 | Nader Shaikh |
| A Study of SHR-1918 In Participants With Hypertriglyceridemia SHR-1918/ SHR-1918 placebo | Recruiting → Active not recruiting | Phase 3 | Beijing Suncadia Pharmaceuticals Co., Ltd |
| Dual Tasking Training to Enhance Self-Efficacy in Individuals With Parkinson's Disease dual tasking training | Not yet recruiting → Recruiting | Not applicable | Alvaro Reyes |
| Digital Intervention for Adults With Misophonia Acceptance and commitment therapy | Recruiting → Completed | Not applicable | Utah State University |
| Quality of Recovery After Day Care Surgery With App Controlled Remote Monitoring: a Randomized Controlled Trial Remote monitoring | Unknown → Completed | Not applicable | Onze Lieve Vrouwe Gasthuis |
| Mastering Diabetes Study Mastering Diabetes | Active not recruiting → Completed | Not applicable | Ohio University |
| Longitudinal Identity Study of Childhood Cancer Survivors Questionnaire bundle, Obtaining information from survivors' medical file | Unknown → Completed | KU Leuven | |
| The Effect of a Micro-Appreciation Intervention (Three-Things Journal Application) on Caregiver Burden, Family Functioning, and Happiness Levels for Mothers of Children With Autism Spectrum Disorder Positive Event Writing Intervention | Recruiting → Completed | Not applicable | Cukurova University |
| Evaluation of Amblyopia Protocols Using a Dichoptic Gabor Videogame Program Visionary: computer exercises using dichoptic Gabor Patches and band-filtered noise masks, Patching | Unknown → Completed | Not applicable | Hospital de Merida |
| Maxillary Arch Distalization With Infrazygomatic Crest Miniscrews for Class II Malocclusion Infrazygomatic Crest Miniscrews | Not yet recruiting → Recruiting | Not applicable | Mansoura University |
| EffecT of eARly analGesia With Erector Spinae Plane Block to Reduce Ventilation After Severe Chest Trauma ESP block | Recruiting → Completed | Not applicable | University Hospital, Grenoble |
| A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study AAA617, Gonadotropin-releasing hormone (GnRH) analogues, Gonadotropin-releasing hormone (GnRH) antagonists | Recruiting → Active not recruiting | Phase 1 | Novartis Pharmaceuticals |
| Gastric US in ICU Patient Gastric Ultrasound | Unknown → Withdrawn Not enough resources (time and manpower) to run study. | Not applicable | Dartmouth-Hitchcock Medical Center |
| Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for CKD AlloRx | Recruiting → Terminated Inadequate treatment response observed in preliminary data did not justify enrolling further study participants | Phase 1 | The Foundation for Orthopaedics and Regenerative Medicine |
| Morphine or Ketamine for Analgesia Ketamine hydrochloride, Morphine sulphate | Not yet recruiting → Recruiting | Phase 3 | Columbia University |
| A Study to Learn More About the Treatment of People With Congenital Thrombotic Thrombocytopenic Purpura (cTTP) Who Received Recombinant ADAMTS13 (rADAMTS13) as Part of the Early Access Program No Intervention | Not yet recruiting → Recruiting | Takeda | |
| An Open-label, Uncontrolled Study of ONO-4578 and ONO-4538 in Combination With Standard-of-care Docetaxel and Ramucirumab as Second-line Therapy in Patients With Advanced or Recurrent Non-small Cell Lung Cancer ONO-4578, ONO-4538, Docetaxel | Active not recruiting → Completed | Phase 1 | Ono Pharmaceutical Co., Ltd. |
| IMProving Adherence to Colonoscopy Through Teams and Technology BPB, No PIN, BPB, PIN, No BPB, PIN | Enrolling by invitation → Active not recruiting | Not applicable | University of California, San Francisco |
| Observational Small Intestine and Blood Fingerprint (SmIle) Study in Parkinson's Disease Fluid biopsy capsule, Levodopa-Carbidopa Immediate Release | Active not recruiting → Terminated Study recruitment phase exceeded the time allotted | Nimble Science Ltd. | |
| Comparison Between the Effects of Implantable Gestrinone and Oral Dienogest in the Treatment of Endometriosis Implantable gestrinone, Oral Dienogest | Unknown → Recruiting | Phase 4 | Bio Meds Pharmaceutica Ltda |
| A Clinical Study to Assess the Effectiveness of Use of Three Experimental Denture Adhesives Compared to Using No-Adhesive Experimental Denture Adhesive 1, Experimental Denture Adhesive 2, Experimental Denture Adhesive 3 | Recruiting → Completed | Not applicable | HALEON |
| Ovarian Cancer Screening and AI ChatGPT - Control, ChatGPT - Evidence-Based Screening Discussion | Not yet recruiting → Completed | Not applicable | Charite University, Berlin, Germany |
| Impact of Live Streaming Exercise on Liver Health in MASLD Pregnant Women Live Streaming Exercise | Not yet recruiting → Completed | Not applicable | Peking University |
| Safety of Cultured Allogeneic Adult Umbilical Cord Stem Cells for Peyronie's Disease, ED, and Interstitial Cystitis AlloRx | Recruiting → Terminated Inadequate treatment response observed in preliminary data did not justify enrolling further study participants | Phase 1 | The Foundation for Orthopaedics and Regenerative Medicine |
| Comparison of Whole Body DWI to FDG PET Fluorodeoxyglucose F18, Positron Emission Tomography combined with Magnetic resonance imaging (PET/MRI), Whole Body Magnetic Resonance Imaging with Diffusion-Weighted Imaging (WB-MRI-DWI) | Recruiting → Active not recruiting | Not applicable | University of California, San Francisco |
| Adjunctive Sirolimus and Oseltamivir Versus Oseltamivir Alone for Treatment of Influenza sirolimus and oseltamivir, Oseltamivir | Unknown → Active not recruiting | Phase 3 | Chinese University of Hong Kong |
| Lung US for PEEP Optimization in Robotic Radical Prostatectomy or Cystectomy Patients Lung Ultrasound - guided Stepwise PEEP, Standard Ventilation Protocol | Active not recruiting → Completed | Not applicable | Nazmy Edward Seif |
| A Novel Multiplex ELISA Assay for Evaluating Patients With Gross Hematuria for Bladder Cancer | Active not recruiting → Completed | Cedars-Sinai Medical Center | |
| Family Intervention to Prevent Childhood Obesity Family-Based Childhood Obesity Intervention | Recruiting → Enrolling by invitation | Not applicable | University of California, Los Angeles |
| HIFU for Treatment of Non-nodular and Recurrent BCC TOOsonix system ONE-M | Active not recruiting → Completed | Not applicable | Joergen Serup |
| A Digital Health Intervention to Improve Symptoms and Physical Activity During Breast Radiation IM@Home Program, Medical Device Usage and Evaluation, Questionnaire Administration | Active not recruiting → Completed | Not applicable | University of Washington |
| Anesthetic Sensitivity Assessed by Alpha Band Power and Its Association With Emergence Time From Sevoflurane General Anesthesia in Young Adults. Intraoperative EEG Recording | Not yet recruiting → Recruiting | University of Chile | |
| Comparison of Two Postoperative Care Strategies After Breast Surgery Patient Education, Paracetamol, Dexketoprofen | Not yet recruiting → Recruiting | Not applicable | Moumtzidou Maria Aikaterini |
| Stem Cell Therapy for Intracerebral Hemorrhage Device: Phase Ⅰ Dose Level 1, Device: Phase Ⅰ Dose Level 2, Device: Phase Ⅰ Dose Level 3 | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | Tang Zhouping |
| Self-Concept Reinforcement for Early School Readiness Self-Concept Reinforcement for Early School Readiness, Reach Out and Read | Recruiting → Not yet recruiting | Not applicable | Children's Hospital Los Angeles |
| Comparison of Intertransverse Process and Erector Spinae Plane Blocks in Acute Postoperative Analgesia Management for Laparoscopic Cholecystectomy Patients Intertransverse Process Block, Erector Spinae Plane Block | Recruiting → Active not recruiting | Not applicable | Konya City Hospital |
| Invasive Decoding and Stimulation of Altered Reward Computations in Depression Patients Brain stimulation | Recruiting → Completed | Not applicable | Icahn School of Medicine at Mount Sinai |
| Sleep Quality in Adolescents With Idiopathic Scoliosis | Not yet recruiting → Recruiting | Bezmialem Vakif University | |
| Statistical Learning as a Novel Intervention for Cortical Blindness Vision Training and Learning Task | Enrolling by invitation → Active not recruiting | Not applicable | University of Rochester |
| Virtual Reality-Assisted Intraoperative Sensory Modulation on Postpartum Depression and the Kynurenine Pathway | Active not recruiting → Completed | Duzce University | |
| Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia MRF with neurocognative studies | Suspended → Recruiting | Not applicable | Case Comprehensive Cancer Center |
| A Study of Trastuzumab Deruxtecan in People With Non-Small Cell Lung Cancer Trastuzumab Deruxtecan | Recruiting → Withdrawn sponsor closed study | Phase 2 | Memorial Sloan Kettering Cancer Center |
| Cisplatin-induced Cochlear and Vestibular Damage in Head and Neck Cancer | Not yet recruiting → Recruiting | Simon Jäger | |
| A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome zorevunersen, Sham Comparator | Recruiting → Active not recruiting | Phase 3 | Stoke Therapeutics, Inc |
| The Effect of the Developed Psychological Resilience Program on Phubbing Behaviors and Communication Skills Psychological Resilience Development Program for Phubbing | Not yet recruiting → Completed | Not applicable | Eastern Mediterranean University |
| Efficacy and Safety of Oral Nicotinamide as an Adjunctive Therapy in Patients With Sepsis Nicotinamide 1000 mg | Not yet recruiting → Completed | Phase 4 | Ain Shams University |
| Effectiveness of Intraligament vs IANB Anesthesia in Children Using Electronic Syringe Electronic Syringe Intraligament Technique, Electronic syringe IANB Technique | Recruiting → Completed | Not applicable | Latakia University |
| The BALANCE Study - Improving Glucose Control Through Prebiotic Gut Health Drink in Postmenopausal Women ió everyday (a prebiotic- enriched gut health drink containing inulin), Placebo Comparator | Not yet recruiting → Completed | Not applicable | University of Roehampton |
| Treatment of Rotator Cuff Tears With Platelet Rich Plasma Platelet Rich Plasma (PRP) | Withdrawn → Completed | Not applicable | The Foundation for Orthopaedics and Regenerative Medicine |
| Evaluating the Response of the Immune System of People With Long COVID (Post SARS-CoV-2) | Unknown → Completed | Huntington Memorial Hospital | |
| FMT for Pediatric SR-aGVHD Fecal Microbial Transplantation | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | Bambino Gesù Hospital and Research Institute |
| Effectiveness and Implementation Evaluation of NeoMayor for Improving Cardiovascular Health in Chilean Older Adults NeoMayor App, Wearable Device Support, Human Health Coach Support | Not yet recruiting → Recruiting | Not applicable | University of Chile |
| Evaluation of Structural and Functional Integrity of the Rotator Cuff After Total Shoulder Arthroplasty CT scan of the shoulders | Recruiting → Terminated low enrollment | Not applicable | Milton S. Hershey Medical Center |
| RAD 1802: Pilot Trial of Five Fraction Stereotactic Body Radiotherapy for Early Stage Breast Cancer Patients Eligible for Post-Operative Accelerated Partial Breast Irradiation (APBI) 5 Fraction Stereotactic Body Radiation Therapy | Recruiting → Active not recruiting | Not applicable | University of Alabama at Birmingham |
| 225 IU Versus 300 IU Starting FSH Dose in PPOS for Good-Prognosis Women Follitropin Alfa (Follitrope) | Not yet recruiting → Recruiting | Not applicable | Vietnam Military Medical University |
| Development of Endoscopic Treatment for Achalasia POEM | Active not recruiting → Completed | Not applicable | Karolinska Institutet |
| Telaglenastat + Talazoparib In Prostate Cancer Telaglenastat, Talazoparib | Unknown → Withdrawn Calithera pulled out of this trial. | Phase 2 | Massachusetts General Hospital |
| Durvalumab as Consolidation Therapy in Patients With LS-SCLC Following sCRT | Recruiting → Completed | The First Affiliated Hospital with Nanjing Medical University | |
| Effect of Food-derived Active Components on Digestive Tract Health in Adults With Irritable Bowel Syndrome Prebiotic_L, resveratrol_L, Prebiotic_M | Not yet recruiting → Completed | Not applicable | Peking University |
| Impact of Metformin on Immuno-virologic Parameters in HIV Metformin | Recruiting → Terminated During the COVID pandemic, our IRB halted enrollment into the study among other changes. Post COVID it was decided that too long an interval between patient enrollment was problematic for the study and a discussion was made to terminate. | Phase 2 / Phase 3 | University of Hawaii |
| Effects of Blood Flow Restriction Training on Physical Function, Muscle Adaptations, and Performance in Roller Skaters Blood Flow Restriction Roller Skating Training, Standardized Roller Skating Training | Not yet recruiting → Active not recruiting | Not applicable | Shanghai University of Sport |
| A Study of of HOT1030 in Patients With Advanced Solid Tumors HOT-1030 | Unknown → Completed | Phase 1 | Huabo Biopharm Co., Ltd. |
| Sodium Oxybate for Postoperative Sleep Disturbance After Thoracic Surgery sodium oxybate, Placebo | Not yet recruiting → Recruiting | Not applicable | Jingsheng Lou |
| A Study Evaluating the Safety of Inavolisib and Fulvestrant With or Without Palbociclib in Participants With Advanced Breast Cancer (ABC) and Type 2 Diabetes Inavolisib, Fulvestrant, Palbociclib | Not yet recruiting → Recruiting | Phase 2 | Hoffmann-La Roche |
| Acceptability and Feasibility of an 8-week Online Mindfulness-Based Cognitive Therapy Program Among Undergraduate Students Mindfulness-Based Cognitive Therapy | Unknown → Completed | Not applicable | Universidad de los Andes, Chile |
| Bexmarilimab + Azacitidine Versus Placebo + Azacitidine in Participants With Treatment-naïve Higher-risk Myelodysplastic Syndromes bexmarilimab (1mg/kg), azacitidine, Placebo | Not yet recruiting → Recruiting | Phase 2 | Faron Pharmaceuticals Ltd |
| Evaluating a School-based Social and Material Needs Identification System to Prevent Youth Violence Involvement Pathways to Potential | Active not recruiting → Completed | University of Michigan | |
| Study of the Effect of Haemodialysis on the Pharmacokinetics, Safety, and Tolerability of Balcinrenone/Dapagliflozin Balcinrenone/dapagliflozin | Recruiting → Completed | Phase 1 | AstraZeneca |
| Effect of Ice Pack and Warm Gel Pad Use During Drain Removal on Anxiety, Comfort, Physiological Parameters, and Patient Satisfaction Undergoing Open Urological Surgery Ice Pack, Warm Gel Pad Group | Recruiting → Completed | Not applicable | Tarsus University |
| Pilot Study of Anesthesiologists' Preoperative Prediction of Postoperative Intensive Care Unit Admission Preoperative Clinical Prediction of Postoperative ICU Admission | Recruiting → Completed | Van Training and Research Hospital | |
| IgG Binding Protein LT in Support of a Healthy Gut on the Go IgG Binding Protein LT, Placebo | Not yet recruiting → Recruiting | Not applicable | Bactolife A/S |
| A Trial of HRS-1780 in Participants With Uncontrolled Hypertension or Resistant Hypertension. HRS-1780 tablet, HRS-1780 tablet placebo | Not yet recruiting → Recruiting | Phase 2 / Phase 3 | Shandong Suncadia Medicine Co., Ltd. |
| The TearAD Study: Tear Biomarkers for Alzheimer's Disease (AD) Screening and Diagnosis Tear Fluid collection (Schirmer's strip), Retinal imaging | Unknown → Completed | Maastricht University Medical Center | |
| Neurocognitive Factors in EdTech Intervention Response GraphoLearn reading intervention, Math control intervention | Active not recruiting → Completed | Not applicable | University of Connecticut |
| PROACT AYA: Preventing Overweight/Obesity-Associated Cardiotoxicity With Tirzepatide In Adolescent And Young Adult Cancer Survivors - A Phase 2 Single-Arm, Single-Center Feasibility Study Tirzepatide | Not yet recruiting → Recruiting | Phase 2 | M.D. Anderson Cancer Center |
| Measuring Corneal Parameters Investigational device, Comparator device | Recruiting → Completed | Not applicable | Icare Finland Oy |
| Multinational Phase II Trial to Compare Safety and Efficacy of SIRT (Y-90 Resin Microspheres) Followed by Atezolizumab Plus Bevacizumab, vs SIRT (SIRT-Y90) Followed by Placebo in Locally Advanced HCC Patients SIRT-Y90 with Atezolizumab + Bevacizumab, SIRT-Y90 with Placebo (IV) | Recruiting → Active not recruiting | Phase 2 | National Cancer Centre, Singapore |
| Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study 18-F FDG | Recruiting → Completed | Not applicable | University Health Network, Toronto |
| An Observational, Prospective, Multicenter Study to Evaluate the Biologic Use and Outcomes in Chinese Asthma Patients | Active not recruiting → Completed | AstraZeneca | |
| Transcranial Ultrasonography for the Management of Patients With Mild TBI Transcranial Doppler (TCD) | Active not recruiting → Completed | Not applicable | University Hospital, Grenoble |
| CEB-01 in Pediatrics With Locally Resectable Abdominal Tumors Standard surgery, CEB-01 | Recruiting → Active not recruiting | Phase 2 | CEBIOTEX |
| Prevalence of Non-alcoholic Fatty Liver Disease Among Non-obese Obstructive Sleep Apnea by Using Transient Elastography | Unknown → Completed | Chinese University of Hong Kong | |
| A Study of RO7830698 in Healthy Participants and Participants With Chronic Obstructive Pulmonary Disease RO7830698, Placebo | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | Hoffmann-La Roche |
| Nirogacestat in Patients With Kaposi Sarcoma Biospecimen Collection, Chest Radiography, Computed Tomography | Not yet recruiting → Recruiting | Phase 2 | AIDS Malignancy Consortium |
| PrEcision Pacing in HFpEF: the PEP-HFpEF Trial Individualized myPACE pacemaker programming | Not yet recruiting → Recruiting | Not applicable | Tufts Medical Center |
| A Bifido Bacteria to Improve Lactose Digestion and Tolerance Bifidobacterium adolescentis IVS-1 capsule, Placebo cellulose capsule | Unknown → Completed | Not applicable | Purdue University |
| A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease GDC-6988 | Recruiting → Terminated Sponsor's Decision | Phase 1 | Genentech, Inc. |
| eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer Pre-Test Intervention, Standard of Care, Post-Test Intervention | Recruiting → Active not recruiting | Not applicable | Abramson Cancer Center at Penn Medicine |
| A Study to Evaluate INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor Naive INCB099280 | Active not recruiting → Terminated This was a strategic business decision. There were no safety concerns contributing to this decision. | Phase 2 | Incyte Corporation |
| Improving Speech in Noise Perception for Individuals With Age-related Hearing Loss transcutaneous auricular vagus nerve stimulation, Sham Control | Recruiting → Completed | Not applicable | University of Florida |
| A Study to Evaluate INCB099280 in Participants With Advanced Cutaneous Squamous Cell Carcinoma INCB099280 | Active not recruiting → Terminated This was a strategic business decision. There were no safety concerns contributing to this decision. | Phase 2 | Incyte Corporation |
| Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015) Tulisokibart, Placebo | Recruiting → Active not recruiting | Phase 2 | Merck Sharp & Dohme LLC |
| Functional Cure Rate of Peg-IFNα-2b Combined With TAF in HBeAg Negative CHB Patients PEG IFN α-2b; TAF | Unknown → Completed | Not applicable | Huashan Hospital |
| Efficacy and Safety of Fruquintinib in Combination With Sintilimab in Advanced Renal Cell Carcinoma (FRUSICA-2) fruquintinib+sintilimab, axitinib / everolimus, fruquintinib | Active not recruiting → Completed | Phase 2 / Phase 3 | Hutchmed |
| Retrospective Observational Study of Implant-supported Restorations With Dental Implants. Dental Implants installed in an grafted area (sinus lifting), Dental Implants installed in an grafted area (ridge augmentation), Dental Implants installed in an grafted area (extraction sites) | Unknown → Terminated The study was not terminated because we changed the methodology of the patient recruitment | Not applicable | M3 Health |
| CM for Patients With ALD After Liver Transplant Contingency Management | Active not recruiting → Completed | Not applicable | Arpan A. Patel, MD |
| Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer Biopsy Procedure, Biospecimen Collection, Computed Tomography | Recruiting → Suspended Other - DSMB decision | Phase 1 / Phase 2 | National Cancer Institute (NCI) |
| Assessment of PK Similarity of FYB206 in Comparison With Keytruda in Resected Stage II or III Melanoma Patients FYB206, Keytruda | Active not recruiting → Completed | Phase 1 | Formycon AG |
| Cross-sectional Study of Sleep Disturbance in Hong Kong Children With Cancer Comparing With Healthy Counterparts and Children With Other Chronic Diseases | Recruiting → Completed | Chinese University of Hong Kong | |
| A Study of ES102 in Combination With Toripalimab in Subjects With Advanced Non-small Cell Lung Cancer ES102, Toripalimab | Recruiting → Active not recruiting | Phase 2 | Elpiscience (Suzhou) Biopharma, Ltd. |
| Exploring the Relationship Between Caring Experience, Perceived Behavioral Control, and Caring Intention Among Students | Recruiting → Completed | Chiu Shu-Ching | |
| Neuroscience-Based Exercise Training in Female Volleyball Players Exercise | Recruiting → Completed | Not applicable | Özge Ecem Şenel |
| Hyperlipoproteinemia A as a Marker of Cardiovascular Risk in Patients With Stage 4 Chronic Kidney Disease lipoprotein A level dosing | Not yet recruiting → Recruiting | Centre Hospitalier Universitaire de Nīmes | |
| Two Tutorial Action Programs, Incidental and Structured, on the General Welfare of Elementary School Students. Structured emotional education program (PEE), Incidental tutorial action based on the school's regular curriculum (PCO) | Unknown → Completed | Not applicable | OIHANA SAGASTI ARRIEN |
| Cytomegalovirus Reactivation in ICU Patients Requiring Prolong Mechanical Ventilation | Unknown → Completed | Sanjay Gandhi Postgraduate Institute of Medical Sciences | |
| Feasibility Study Comparing Use of One Or Two Probes for Thermal Ablation Among Screen Positive Women Living With HIV in C1001P-CS2 Kenya Thermal ablation (TA) with 1 probe, Thermal ablation (TA) with 2 probes | Not yet recruiting → Recruiting | Not applicable | Fred Hutchinson Cancer Center |
| Narrow Excision Versus Wide Excision for the Treatment of Adults With Invasive Cutaneous Melanoma, ICEMAN Trial Biospecimen Collection, Excision, Survey Administration | Recruiting → Suspended Pending coordinating center transition | Not applicable | OHSU Knight Cancer Institute |
| Acute Effects of a Urate-lowering Bacterial Therapeutic on Small Intestinal Transcriptomics and Glycomics in Healthy Subjects BEO001 Probiotic, BEO001 Probiotic + Beta-Glucan, Placebo | Not yet recruiting → Active not recruiting | Not applicable | Örebro University, Sweden |
| Investigate the Efficacy and Safety of BRII-835 (VIR-2218) and PEG-IFNα Combination Therapy in Chronic HBV Patients PEG-IFNα, BRII-835 | Active not recruiting → Completed | Phase 2 | Brii Biosciences Limited |
| Clinical Study on Circadian Genes Dysregulation in Patients With Glucocorticoid Disorders circadian gene expression evaluation | Unknown → Recruiting | Not applicable | University of Roma La Sapienza |
| A Study of IBI362 in Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH) Placebo, IBI362 | Recruiting → Active not recruiting | Phase 2 | Innovent Biologics (Suzhou) Co. Ltd. |
| TNF-α Treatment of Blast-Induced Tinnitus Etanercept, Saline | Recruiting → Active not recruiting | Phase 2 | Wayne State University |
| Safety of CRT100 on Treatment Spinal Cord Injury CRT100 | Not yet recruiting → Recruiting | Phase 1 | Cristália Produtos Químicos Farmacêuticos Ltda. |
| Effect of Stress Ball Application During Coronary Angiography on Anxiety, Procedure-related Fear, Physiological Parameters, and Comfort Stress ball | Not yet recruiting → Recruiting | Not applicable | Tarsus University |
| Hospital Airway Resuscitation Trial A strategy of first choice supraglottic airway, A strategy of first choice endotracheal intubation | Recruiting → Completed | Not applicable | Montefiore Medical Center |
| A Study to Learn How the Study Medicine Called Etrasimod is Taken up Into Blood and Breastmilk of Healthy Breastfeeding Women Etrasimod | Active not recruiting → Completed | Phase 1 | Pfizer |
| Bicuspid Aortic Valve (BAV) Registry | Recruiting → Enrolling by invitation | University of Michigan | |
| Outpatient Management of Primary Spontaneous Pneumothorax: Pigtail Catheter With Unidirectional Valve vs. Exsufflation, Randomized Prospective Study Fuhrman catheter insertion, Three-way stopcock open, Manual aspiration | Recruiting → Active not recruiting | Not applicable | Rennes University Hospital |
| Radical Prostatectomy Without Prior Biopsy Transperineal Fusion-Targeted Prostate Biopsy With Intraoperative Frozen Section Examination, Robot-Assisted Radical Prostatectomy With Pelvic Lymph Node Dissection, Standard Transperineal Fusion Prostate Biopsy | Not yet recruiting → Recruiting | Not applicable | Botkin Hospital |
| Effect of Music Therapy Applied During Lumbar Puncture on Infants' Pain Perception music | Enrolling by invitation → Completed | Not applicable | Erzurum Technical University |
| Managed Access Programs for TQJ230, Pelacarsen Pelacarsen | Available → No longer available | Novartis Pharmaceuticals | |
| Atezolizumab + Cabozantinib in Patients w/ Metastatic, Refractory Pancreatic Cancer Cabozantinib + Atezolizumab | Active not recruiting → Completed | Phase 2 | University of Arizona |
| Guided Bone Regeneration Using Polydioxanone (PDO) Membrane in Sockets After Tooth Extraction Plenum® Guide, Plenum® Oss, Tooth extraction | Unknown → Recruiting | Not applicable | M3 Health |
| The Impact of Soft Contact Lenses on the Corneal Neuromediators and Optical Quality in High Myopia Prior to SMILE This study does not involve any interventions | Recruiting → Completed | yuhao shao | |
| Ultrasound-Guided Repeated Saline Injections to Prevent and Treat Tendon Adhesions After Hand Tendon Repair Ultrasound-Guided Repeated Normal Saline Injections | Not yet recruiting → Recruiting | Not applicable | Kai Wang |
| Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for IPF AlloRx | Recruiting → Terminated Inadequate treatment response observed in preliminary data did not justify enrolling further study participants | Phase 1 | The Foundation for Orthopaedics and Regenerative Medicine |
| Primary Prevention of Cardiovascular Disease Among Female Hospital Employees: The Heart Smart for Women Intervention Heart Smart Interventional Program | Unknown → Completed | Not applicable | Northwell Health |
| Comparing the Adaptation of Commercial Milk and A2 Milk in Lactose Maldigesters Milk containing A1 and A2 beta-casein, Milk containing only A2 beta-casein | Unknown → Completed | Not applicable | Purdue University |
| A Study to Assess Intravenous ABBV-1480 Combined With Chemotherapy Versus Pembrolizumab Combined With Chemotherapy for the First Line Treatment of Locally Advanced/Metastatic Non-Small Cell Lung Cancer in Adult Participants ABBV-1480, Pembrolizumab, Carboplatin | Not yet recruiting → Recruiting | Phase 3 | AbbVie |
| In Vivo Imaging of the Olfactory Epithelium Using Confocal Laser Endomicroscopy CONVIVO system, Fluorescein injection, USP 10% | Active not recruiting → Not yet recruiting | Early Phase 1 | Dartmouth-Hitchcock Medical Center |
| Pulsed Lavage in Implant-Based Breast Reconstruction Pulsed Lavage Washout, Implant-based breast reconstruction, Bilateral or unilateral mastectomy | Recruiting → Terminated Changes in personnel | Not applicable | University of Alabama at Birmingham |
| Multimodal Intervention for Weight Management and Health in the Elderly Population Nutritional guidance focused on adopting a high-protein diet., Group Cognitive Behavioral Therapy Intervention, Resistance Training Program | Not yet recruiting → Recruiting | Not applicable | Universidade Cesumar (UNICESUMAR) |
| Plenum® Osshp in Maxillary Sinus Elevation Surgery Group 1: Autogenous bone graft, Group 2: Plenum® Osshp, Group 3: Plenum® Osshp; + i-PRF | Unknown → Completed | Not applicable | M3 Health |
| Is Our Microbiome a Predictor of Cardiac Risk | Enrolling by invitation → Suspended Reorganizing study personnel and funding | Mayo Clinic | |
| Safety and Efficacy Study of Safusidenib in Participants With IDH1-Mutant Glioma Who Discontinued Vorasidenib Treatment Due to Progressive Disease Safusidenib | Not yet recruiting → Recruiting | Phase 2 | Nuvation Bio Inc. |
| PSMA PET Combined With MRI for the Detection of PCa 68Ga-PSMA-11 | Recruiting → Active not recruiting | Phase 3 | Telix Pharmaceuticals (Innovations) Pty Limited |
| Therapeutic Support to Strengthen Dignity, Mental Well-being and Quality of Life in Acute Palliative Care Patients. Therapeutic support, Standard Specialized Palliative Consultation Service | Unknown → Completed | Not applicable | University Hospital, Basel, Switzerland |
| Prospective Validation of Adaptive Radiotherapy (ART) in Patients With Head and Neck Tumors Adaptive Radiotherapy | Recruiting → Completed | Not applicable | University Hospital, Essen |
| Adaptive Radiotherapy in Head and Neck Tumor Patients Adaptive Radiotherapy, image guided radiotherapy without online adaptation | Recruiting → Completed | Not applicable | University Hospital, Essen |
| Dynamic Airway CT is Diagnostic for Tracheomalacia in Children Dynamic Airway CT scan (DA-CT) | Recruiting → Completed | Not applicable | NYU Langone Health |
| Celiac Disease in Childhood-Adulthood Transition CeliCAT form | Enrolling by invitation → Active not recruiting | Not applicable | Tampere University Hospital |
| THE IMPACT OF WHATSAPP BASED EX-PLISSIT MODEL SEXUAL COUNSELING ON THE SEXUAL LIVES OF BREAST CANCER SURVIVORS Sexual counseling group based on the EX-PLISSIT Model | Active not recruiting → Completed | Not applicable | Karamanoğlu Mehmetbey University |
| Clinical Evaluation of Short Dentin Etching Resin composite restoration bonded using universal adhesive in etch and rinse mode (15 seconds etching), Resin composite restoration bonded using universal adhesive in etch and rinse mode (5 seconds etching), Resin composite restoration bonded using universal adhesive in self-etch mode | Recruiting → Active not recruiting | Not applicable | Mansoura University |
| Antegrade Autologous Blood Reinfusion After CPB Antegrade Pump Blood Reinfusion, No Anterograde Pump Blood Reinfusion | Recruiting → Completed | Kocaeli City Hospital | |
| EHR Precision Drug Treatment in Neonates | Unknown → Completed | Children's Hospital Medical Center, Cincinnati | |
| The Critical Link Between Gut Microbiome Dysfunction, Cravings and Relapse: RECLAIM-GUT TRIAL Personalized prebiotic dietary Formulation 2, Personalized prebiotic dietary Formulation 3, Personalized prebiotic dietary Formulation 1 | Active not recruiting → Completed | Not applicable | University of Roehampton |
| Effectiveness of the Self-Control Module of a Positive Mental Health Promotion Programme for Adult Informal Caregivers of People With Dementia: Protocol for a Randomised Controlled Trial Mentis Plus+ Caregivers | Recruiting → Active not recruiting | Not applicable | University Rovira i Virgili |
| Effect of Preoperative Diet on Perioperative Gut Microbiome high-fiber, fermented | Unknown → Completed | Not applicable | Stanford University |
| Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell IV Infusion for Systemic Sclerosis AlloRx | Recruiting → Terminated Inadequate treatment response observed in preliminary data did not justify enrolling further study participants | Phase 1 | The Foundation for Orthopaedics and Regenerative Medicine |
| Prevention of Functional and Cognitive Impairment Through a Multicomponent Exercise Program in Hospitalized Older Adults Exercise | Recruiting → Completed | Not applicable | Fundacion Miguel Servet |
| Volume Kinetics of Fluid Resuscitation in Early Sepsis Ringer's Lactate | Recruiting → Completed | Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu | |
| Berzosertib and Irinotecan in Treating Patients With Progressive, Metastatic, or Unresectable TP53 Mutant Gastric or Gastroesophageal Junction Cancer Berzosertib, Computed Tomography Assisted Biopsy, Endoscopic Biopsy | Active not recruiting → Completed | Phase 2 | National Cancer Institute (NCI) |
| Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas Biospecimen Collection, Computed Tomography, Incomplete Freund''s Adjuvant | Suspended → Not yet recruiting | Phase 2 | Roswell Park Cancer Institute |
| Improving Medication Management in World Trade Center Responders Educational brochure for deprescribing | Recruiting → Active not recruiting | Not applicable | Icahn School of Medicine at Mount Sinai |
| Surgical Ergonomics in OBGYN Surgical Ergonomics Lecture, Pre-Incision Surgical Ergonomics Time Out, Intra-operative stretch breaks | Not yet recruiting → Recruiting | Not applicable | University Hospitals Cleveland Medical Center |
| Transcranial Doppler as a Predictor of Postoperative Cognitive Dysfunction Following Cardiopulmonary Bypass Transcranial Doppler measurement of the middle cerebral artery | Recruiting → Completed | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | |
| Baroloop Multicenter Trial (Baroloop MCT) baroloop system | Recruiting → Terminated Terminated following a device deficiency in 1 subject. Benefit-risk and development assessments did not support continuation within the planned framework. Root cause analysis pending. | Not applicable | neuroloop GmbH |
| Optimization of Surgical Treatment of Patients With Incisional Ventral Hernias A new method of repair of the abdominal wall of mid-lateral postoperative ventral hernias | Recruiting → Completed | Not applicable | Samara State Medical University |
| Genetic and Physical Study of Childhood Nerve and Muscle Disorders | Active not recruiting → Completed | National Institute of Neurological Disorders and Stroke (NINDS) | |
| Adaptive Radiotherapy in Patients With Gynecological Tumors Adaptive Radiotherapy | Recruiting → Completed | Not applicable | University Hospital, Essen |
| A Comprehensive Group Intervention for Psychosocial Personnel at Risk of Stress and Moral Injury CARE MI, TAU: Treatment as usual | Enrolling by invitation → Completed | Not applicable | Universidad Complutense de Madrid |
| A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies Inlexisertib, Ripretinib | Recruiting → Active not recruiting | Phase 1 / Phase 2 | Deciphera Pharmaceuticals, LLC |
| HRS-7450 Injection Phase II Clinical Trial for Acute Ischemic Stroke. HRS-7450 Injection, HRS-7450 Injection Placebo | Active not recruiting → Completed | Phase 2 | Fujian Shengdi Pharmaceutical Co., Ltd. |
| A Phase 2 Trial to Investigate Efficacy and Safety of Vipoglanstat in Women With Endometriosis Vipoglanstat, Placebo | Recruiting → Active not recruiting | Phase 2 | Gesynta Pharma AB |
| The Effect of Yoga Applied to Primiparous Pregnant Women on Postpartum Depression and Maternal Attachment prenatal yoga | Active not recruiting → Completed | Not applicable | Muş Alparslan University |
| Administration of High Doses of Antiretroviral Drugs to Eliminate the Latent HIV-1 Reservoir Standardised triple antiretroviral therapy, High doses Triple therapy antiretroviral drugs | Recruiting → Active not recruiting | Phase 2 | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal |
| NMR Based Metabolomics Kinetics in ARDS Patients | Recruiting → Completed | Sanjay Gandhi Postgraduate Institute of Medical Sciences | |
| First-in-Human Safety and Tolerability Study of OPF-110 in Healthy Adults OPF-110, SMOFLIPID | Recruiting → Active not recruiting | Phase 1 | Otsuka Pharmaceutical Factory, Inc. |
| TMS + Exposure Therapy for Pediatric OCD: Second Phase Transcranial Magnetic Stimulation: continuous theta burst to pre supplementary motor area, Transcranial Magnetic Stimulation: Sham, Exposure with Response Prevention | Not yet recruiting → Recruiting | Not applicable | Bradley Hospital |
| Nurse-supported Mobile App for Self-help CBT-I in Informal Cancer Caregivers Nurse-Supported Mobile App for Self-Help CBT-I, Sleep hygiene education | Recruiting → Completed | Not applicable | The University of Hong Kong |
| A Study of Daily Rifapentine Combined With Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age With and Without HIV Rifapentine, Isoniazid, Dolutegravir | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | National Institute of Allergy and Infectious Diseases (NIAID) |
| Prospective Trial of [18F]AlF-FAPI-74 for PET Imaging of Fibroblast Activation Protein in Patients With Endometriosis [18F]AlF-FAPI-74 PET/CT | Not yet recruiting → Recruiting | Not applicable | Universitaire Ziekenhuizen KU Leuven |
| Golimumab and Apalutamide for the Treatment of Castration-Resistant Prostate Cancer, TRAMP Study Apalutamide, Biopsy, Biospecimen Collection | Active not recruiting → Terminated The trial was ended sooner than expected due to a combination of factors, including slow accrual, lower than anticipated benefit to patients, and loss of funding from the study sponsor. | Phase 2 | University of Washington |
| Blood-Brain Barrier Disruption Using Transcranial MRI-Guided Focused Ultrasound Transcranial ExABlate | Active not recruiting → Completed | Not applicable | InSightec |
| The Effect of Exercise on Motion Perception and Fear in Low Back Pain Exercises | Unknown → Completed | Not applicable | Suleyman Demirel University |
| Neuro-MoD: Neuroplasticity With Motor Development Constraint-Induced Movement Therapy (CIMT), Transcutaneous auricular vagus nerve stimulation (taVNS) | Not yet recruiting → Recruiting | Not applicable | University of Wisconsin, Madison |
| Study Evaluating the Safety and Feasibility of Panitumumab-IRDye800 and [18F]NOTA-ABY-030 for Targeted Dual-Modality Imaging (TDMI) in Head and Neck Squamous Cell Carcinoma Panitumumab-IRDye800, [18F]NOTA-ABY-030 | Not yet recruiting → Recruiting | Phase 1 | Vanderbilt-Ingram Cancer Center |
| TMS + Exposure Therapy for Pediatric OCD Transcranial Magnetic Stimulation: intermittent theta burst to dorsolateral prefrontal cortex, Exposure with Response Prevention, Transcranial Magnetic Stimulation: Sham | Recruiting → Completed | Not applicable | Bradley Hospital |
| Balance Rehabilitation Based on Serious Games Experimental: Interactive balance rehabilitation based on serious games., Active Comparator: conventional balance rehabilitation without the use of technological devices. | Recruiting → Completed | Not applicable | IRCCS San Raffaele Roma |
| Improving Student Mental Health Through a Universal Trauma-Informed Intervention RAP Club Delivered by a School Clinician, RAP Club Delivered by a Teacher, Standard Supervision | Not yet recruiting → Recruiting | Not applicable | Johns Hopkins Bloomberg School of Public Health |
| Radial Versus Femoral Secondary Access in Patients Undergoing TAVI Radial TAVI, femoral TAVI | Recruiting → Active not recruiting | Not applicable | University Heart Center Freiburg - Bad Krozingen |
| Evaluation of Diagnostic Accuracy of MCG(Magnetocardiography) Scan in Suspected Coronary Artery Disease Rest/Stress MCG scan, Rest MCG scan | Unknown → Completed | AMCG | |
| Distribution of the Homologous Recombination-related (HRR) Genesmutationsand HRD in Breast Cancer Standard Management | Recruiting → Active not recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| Access to EyeGlasses for School-aged Children Fitz Frames 3-D Printed Glasses | Unknown → Terminated Funding was stopped from source before project could start intervention phase of trial | Not applicable | Boston Children's Hospital |
| Evaluate Pathogens and Immunity to Acute Otitis Media in Healthy Children. procedures | Unknown → Active not recruiting | Rochester General Hospital | |
| Pyronaridine in Acute Myeloid Leukemia (AML) Pyronaridine Tetraphosphate | Unknown → Suspended Change of protocol | Phase 2 | Armaceutica, Inc. |
| OMNI 3.1 Surgical System in Subjects With Primary Open-Angle Glaucoma OMNI 3.0 Surgical System | Recruiting → Active not recruiting | Not applicable | Sight Sciences, Inc. |
| GnRH for Luteal Support in IVF/ICSI/FET Cycles GnRH, placebo | Recruiting → Active not recruiting | Phase 4 | University Reproductive Associates |
| Examining Digital Health Care Delivery Models Through Medicaid Collaborative digital health delivered multicomponent intervention | Recruiting → Active not recruiting | OSF Healthcare System | |
| Impact of B. Adolescentis iVS-1 Probiotic on Gastrointestinal Outcomes Probiotic, Placebo | Active not recruiting → Completed | Not applicable | Synbiotic Health |
| Registry Study of Assistive Devices, Medicines and Healthcare Measures in ALS, SMA and Other Neurological Diseases. | Recruiting → Completed | Ambulanzpartner Soziotechnologie APST GmbH | |
| Study in Human iPSCs-derived RPE Cells Transplantation for Advanced (Late-stage) AMD hiPSC-RPEs | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | The First Affiliated Hospital with Nanjing Medical University |
| The Role of Peripheral Afferents in Modulating Post-stroke Central Pain Lidocaine 20mg/ml, Levobupivacaine Hydrochloride 1.25 MG/ML, Sodium Chloride 0.9% Inj | Recruiting → Completed | Phase 3 | Institut National de la Santé Et de la Recherche Médicale, France |
| Nellcor™ Investigational Device Sitting-Walking Study | Not yet recruiting → Recruiting | Medtronic - MITG | |
| Time-restricted Eating Acceptability, Efficacy and Safety in Obesity Time Restricted Eating | Recruiting → Completed | Not applicable | University of Mississippi, Oxford |
| Opioid Treatment and Peer Recovery Support Core Intervention, Peer Support Specialists (PSS), Treatment as Usual (TAU) | Recruiting → Completed | Not applicable | Brown University |
| Evaluating the Community Drum Circle Communal Drumming, Communal drumming recordings | Enrolling by invitation → Completed | Not applicable | Yale University |
| Improving Jail Response to the Overdose Crisis: A Hybrid Trial of Jail ECHO to Improve MOUD Implementation and Public Health Outcomes Project ECHO | Not yet recruiting → Recruiting | Not applicable | University of Massachusetts, Worcester |
| Application of Remimazolam Combined With Esketamine in Painless Gastroscopy and Colonoscopy in Elderly Patients remimazolam-remifentanil, remimazolam-esketamine | Recruiting → Active not recruiting | Not applicable | Harbin Medical University |
| Upper Limb Rehabilitation in People With Parkinson's Disease: Experimental Group, control group | Recruiting → Completed | Not applicable | IRCCS San Raffaele Roma |
| Drum Circle Synchrony Study 2c.a. Communal drumming recordings | Enrolling by invitation → Completed | Not applicable | Yale University |
| Mindfulness in a College Physiology Course Biology Course with Integrated Mindfulness | Enrolling by invitation → Completed | Not applicable | Trustees of Dartmouth College |
| Effect of Sensorimotor Training on Pain and Gait Performance in Patients With Discogenic Sciatica Standard physical therapy, Sensorimotor Training | Not yet recruiting → Recruiting | Not applicable | Cairo University |
| Antiviral Long Acting Drugs Landing in People Living With HIV Surveys completion, Home administration of CAB+RPV, Hospital administration of CAB+RPV | Active not recruiting → Completed | Not applicable | IRCCS San Raffaele |
| Premixed Glucagon/Insulin Solution for Faster Insulin Absorption in Type 1 Diabetes Lyumjev 100 UNT/ML Injectable Solution, Premixed Lyumjev | Suspended → Terminated The study was terminated due toa combination of: 1. At best minimal effect on insulin absorption 2. Withdrawal of funding as the patent application for using glucagon to enhance subcutaneous insulin absorption was not approved. | Phase 1 / Phase 2 | St. Olavs Hospital |
| Novel Approach to Conduction System Pacing With Use of Ultrasound Ultrasound guidance, Fluoroscopy guided | Active not recruiting → Recruiting | Not applicable | Habib Khan |
| Beta-1 Adrenergic Inhibition to Reduce Cardiac Injury and Inflammation After Subarachnoid Hemorrhage (BADCATS) Metoprolol, Placebo | Recruiting → Active not recruiting | Phase 4 | Madeleine Puissant |
| Neoadjuvant Ipilimumab/Nivolumab for Patients With Recurrent, High Risk, Resectable Melanoma Ipilimumab, Nivolumab | Recruiting → Withdrawn Low Accrual | Phase 2 | University of Utah |
| A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD WVE-006 | Active not recruiting → Recruiting | Phase 1 / Phase 2 | Wave Life Sciences USA, Inc. |
| Axelopran and Nivolumab in PD-1-Refractory Metastatic Melanoma Axelopran, Nivolumab | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | John Kirkwood |
| Evaluation of Aqueous Humor DEL-1 and IL-17 Levels in Diabetic Cataract Patients Observational Study Procedure | Recruiting → Completed | Uşak University | |
| Advancing Strategies to Optimize the PerIopeRativE Management of PostOperative Nausea and Vomiting (ASPIRE-PONV) Trial AW-D Clinical Decision Support Tool | Recruiting → Active not recruiting | Not applicable | Vanderbilt University Medical Center |
| Evaluating the Impact of Social Music Music | Recruiting → Completed | Not applicable | Yale University |
| Telerehabilitation in People With Parkinson's Disease VRRS Tablet (Khymeia s.r.l., Noventa Padovana, Italy), Conventional rehabilitation | Recruiting → Completed | Not applicable | IRCCS San Raffaele Roma |
| Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BGM1812 Injection Following Single and Multiple Subcutaneous Administration in Normal to Overweight or Obese But Otherwise Healthy Men and Women BGM1812, Placebo | Completed → Active not recruiting | Phase 1 | BrightGene Bio-Medical Technology Co., Ltd. |
| Integrated Clinical Decision Support for Empiric Antibiotic Selection in Sepsis Clinical Decision Support Algorithm for Empiric Antibiotics in Sepsis | Recruiting → Terminated Funding. | Not applicable | Ottawa Hospital Research Institute |
| Impact of a Multiplex Respiratory PCR Test on Outcomes for Patients Presenting With Respiratory Illness in the Urgent Care Setting: A Hybrid-Effectiveness Quasi-Experimental Trial SPOTFIRE R/ST Diagnostic Test | Recruiting → Completed | Not applicable | BioMérieux |
| A Phase 3 Clinical Study of QL2106 Injection QL2106 injection, Tremfya® | Recruiting → Active not recruiting | Phase 3 | Qilu Pharmaceutical Co., Ltd. |
| A Study With CIT-013 in HS Patients CIT-013 high dose, CIT-013 medium dose, Placebo | Recruiting → Active not recruiting | Phase 2 | Citryll BV |
| A Study of Caregiver Connections Via Technology in Dementia Algorithm, Random Match | Active not recruiting → Completed | Not applicable | Mayo Clinic |
| A Study of SPY072 in Adults With Moderate to Severe Hidradenitis Suppurativa (The SKYLIGHT Trial) SPY072, Placebo, bimekizumab | Not yet recruiting → Recruiting | Phase 2 | Spyre Therapeutics, Inc. |
| Oral Switch in Pediatric Bloodstream Infections Oral antibiotic therapy, Standard IV antibiotic therapy | Not yet recruiting → Recruiting | Phase 4 | Ulrikka Nygaard |
| A Multi-centre Trial to Assess the Efficacy and Safety of the Omnipod 5 System in People With Type 2 Diabetes Undergoing Haemodialysis Omnipod 5, Insulin injections | Not yet recruiting → Recruiting | Not applicable | Imperial College London |
| Optimizing Outcomes for Young Autistic Children Social Communication, Disruptive Behavior, Social Communication + Reduce Frequency | Recruiting → Active not recruiting | Phase 2 | Northwestern University |
| Lipopolysaccharide Adsorption (Efferon LPS NEO) in Children With Thermal Burns Efferon LPS NEO | Recruiting → Withdrawn No patients meeting the study eligibility criteria were identified | Efferon JSC | |
| Physical Activity Intervention Among Older Women With Gynecologic Cancers (Fit4Treatment) Fit4Treatment | Recruiting → Active not recruiting | Not applicable | Northwestern University |
| Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) Livmoniplimab, Budigalimab, Pembrolizumab | Recruiting → Active not recruiting | Phase 2 / Phase 3 | AbbVie |
| Developing a Decision Tool for Diverticulitis in the Emergency Department Using Ultrasound Ultrasound | Unknown → Completed | Northwell Health | |
| Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes Inhaled Technosphere Insulin | Recruiting → Completed | Phase 2 / Phase 3 | Jaeb Center for Health Research |
| Observatory of Prolymphocytic Leukemia T Molecular caracterization | Recruiting → Active not recruiting | French Innovative Leukemia Organisation | |
| Cooling of the Knee After Total Knee Arthroplasty Cool Down Liquid with Bandage ( CoolDown, CH), Ice package cooling system, Standard Postoperative Protocol Without Cooling | Not yet recruiting → Completed | Not applicable | Clinical Center of Vojvodina |
| Evaluation of Pulpotomy, Partial Pulpotomy, and Direct Pulp Capping Using Mineral Trioxide Aggregate. pulp capping with MTA | Active not recruiting → Completed | Not applicable | Delta University for Science and Technology |
| Pediatric Orotracheal Suctioning Training Using a Benner Model-Based Augmented Reality Application Benner Model-Based Augmented Reality Training, Conventional Mannequin-Based Training | Unknown → Completed | Not applicable | Medipol University |
| Extended Access Program With Lorcaserin For The Treatment of Dravet Syndrome and Other Refractory Epilepsies Lorcaserin | Available → No longer available | Eisai Inc. | |
| EMPOWER 3: Improving Palliative Care Health Literacy and Utilization Multimedia Psychoeducational Intervention, Enhanced Usual Care | Active not recruiting → Completed | Not applicable | Tulane University |
| Telehealth Interventions for Cardiac Surgery Telehealth Monitoring | Active not recruiting → Completed | Not applicable | Liverpool Heart and Chest Hospital NHS Foundation Trust |
| Impact of Early ADL Participation on Outcomes Post DRF ADL/Cast Care instruction, Cast Care Instruction | Recruiting → Completed | Phase 1 | George Washington University |
| Driving After Shoulder Surgery Driving simulator | Unknown → Recruiting | Not applicable | The Hawkins Foundation |
| Hedonic and Homeostatic Appetite Control in Obesity and Type 2 Diabetes in the Context of Meal and Exercise Timing Exercise, Control | Active not recruiting → Completed | Not applicable | Steno Diabetes Center Copenhagen |
| Nivolumab and BMS986205 in Treating Patients With Stage II-IV Squamous Cell Cancer of the Head and Neck Nivolumab, IDO1 Inhibitor BMS-986205, Therapeutic Conventional Surgery | Active not recruiting → Terminated Study was terminated early due to toxicity concerns by the Sponsor. | Phase 2 | Thomas Jefferson University |
| Fibrinogen in Liver Transplant Intercept Fibrinogen Complex (IFC), Cryoprecipitate Antihemophilic Factor (AHF) | Not yet recruiting → Recruiting | Phase 4 | Trauma Hemostatis and Oxygenation Research (THOR) Network |
| Pancoronavirus Vaccine Study in Healthy Adults CoV-RBD-scNP-001 and 3M-052-AF | Active not recruiting → Terminated Adjuvant stability not extended | Phase 1 | Duke University |
| Sleeve Gastrectomy With Jejuno-ileal Bypass Versus Single Anastomosis Sleeve Jejunal Bypass SGJIB, SAS-JB | Unknown → Completed | Not applicable | Minia University |
| Study of HS-20093 Versus Gemcitabine in Combination With Docetaxel in Treatment of Osteosarcoma After Previous Second-line Treatment Failure HS-20093, Gemcitabine combined with docetaxel | Active not recruiting → Completed | Phase 3 | Hansoh BioMedical R&D Company |
| A Phase II Clinical Study of SHR-7787 Injection Combined With SHR-1316 Injection in Patients With LS-SCLC SHR-7787 Injection, SHR-1316 | Not yet recruiting → Recruiting | Phase 2 | Shanghai Hengrui Pharmaceutical Co., Ltd. |
| Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI) Mindfulness-Based Intervention, Organizational Skills Training | Recruiting → Completed | Not applicable | Duke University |
| ADP-A2M4CD8 Monotherapy and in Combination With Nivolumab in HLA-A2+ Subjects With MAGE-A4 Positive Ovarian Cancer (SURPASS-3) Autologous genetically modified ADP-A2M4CD8 cells, Autologous genetically modified ADP-A2M4CD8 cells in combination with Nivolumab | Active not recruiting → Terminated Enrollment was halted following withdrawal of the U.S. IND. Previously enrolled participants completed treatment and follow-up, after which the study was closed. | Phase 2 | USWM CT, LLC |
| Study to Explore the Safety, Tolerability, and Pharmacokinetics of AMG 305 in Subjects With Advanced Solid Tumors AMG 305 | Completed → Terminated Sponsor decision | Phase 1 | Amgen |
| Study to Provide Continued Access to Treatment for Patients Completing a Previous Trial With Efanesoctocog Alfa Efanesoctocog alfa | Recruiting → Active not recruiting | Phase 3 | Swedish Orphan Biovitrum |
| Feasibility Study Comparing One vs Two Probes for TA Among Cervical Cancer Screen Positive WLWH in C1001P-CS5 Rwanda Thermal ablation (TA) with 1 probe, Thermal ablation (TA) with 2 probes | Not yet recruiting → Recruiting | Not applicable | Fred Hutchinson Cancer Center |
| The Effects of Footplate Stiffness on Foot Loading Within Carbon Fiber Custom Dynamic Orthoses Carbon Fiber Custom Dynamic Orthosis, Carbon Fiber Footplate | Recruiting → Completed | Not applicable | Jason Wilken |
| Multi-site Trial of a Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung Cancer Dyspnea Intervention, Enhanced Usual Care | Not yet recruiting → Recruiting | Not applicable | Massachusetts General Hospital |
| Prospective Human Study Evaluating Changes in Markers of Detoxification, Overall Physical and Mental Health, and Fatigue Following Supplementation With CellCore Protocols CellCore Foundational Protocol, CellCore - BioToxin Binder & Drainage Activator | Not yet recruiting → Recruiting | Not applicable | OvationLab |
| A Study to Test How Much BI 3034701 Gets Into the Blood in Healthy People When Given in Two Different Ways BI3034701 formulation II, BI3034701 formulation C1 | Not yet recruiting → Recruiting | Phase 1 | Boehringer Ingelheim |
| Walking Rehabilitation After Spinal Cord Injury: Locomotor Training Using Adaptive Robotics Hybrid Assistive Limb (HAL) | Unknown → Active not recruiting | Not applicable | Brooks Rehabilitation |
| Lipopolysaccharide Adsorption (Efferon LPS) in Patients With Thermal Burns Efferon LPS | Recruiting → Withdrawn No patients meeting the study eligibility criteria were identified | Efferon JSC | |
| A Randomized, Placebo Controlled Trial of L Max in Healthy Adult Athletes L Max, Placebo | Active not recruiting → Completed | Not applicable | Climatic, Inc. |
| Functional Near-infrared Spectroscopy in Unconscious Patients single-center prospective pilot study | Recruiting → Completed | Not applicable | Emanuela Keller |
| GUT-FEELINGS: Using Citizen Science for Large-Scale Prebiotic Clinical Trials for Mental Wellness in Adults Active Gut Feeling Product 1, Active Gut Feeling Product 2, Placebo Gut Feeling Control Product | Not yet recruiting → Recruiting | Not applicable | Holobiome, Inc. |
| A Hybrid Effectiveness/Implementation Trial of the International Guide for Monitoring Child Development International Guide for Monitoring Child Development | Active not recruiting → Completed | Not applicable | Brigham and Women's Hospital |
| Activity for Diabetic Polyneuropathy Standard Care Counseling, Supervised Exercise and Counseling | Unknown → Completed | Not applicable | University of Utah |
| Real-world Evaluation of the Implementation of LC-OCT in Daily Clinical Practice | Not yet recruiting → Recruiting | Maastricht University Medical Center | |
| ANRS0268s POSTCOVIET | Unknown → Completed | ANRS, Emerging Infectious Diseases | |
| Open Label Safety Study of Tradipitant in Idiopathic and Diabetic Gastroparesis Tradipitant | Recruiting → Completed | Phase 3 | Vanda Pharmaceuticals |
| Gait Training Through a Novel Over-ground Wearable Robotic System in People With Pyramidal Hemisyndromes Indego Therapy | Unknown → Active not recruiting | Not applicable | IRCCS San Raffaele Roma |
| Reducing Chronic Pain Following Cesarean Delivery Empowered Relief | Not yet recruiting → Recruiting | Not applicable | Stanford University |
| Evaluating Social Perception Dynamics Social perception tasks | Enrolling by invitation → Completed | Not applicable | Yale University |
| Sub-symptom Threshold Aerobic Exercise After Mild Traumatic Brain Injury Sub-symptom threshold aerobic exercise | Active not recruiting → Completed | Not applicable | Oslo University Hospital |
| Bundle Branch Pacing to Preserve Ejection Fraction in Atrial Fibrillation Trial LBBA pacing, Conventional pacing | Not yet recruiting → Recruiting | Not applicable | Poitiers University Hospital |
| Mindfulness-based Neurofeedback to Augment Psychotherapy for Adults With Borderline Personality Disorder mindfulness-based Neurofeedback, control Neurofeedback | Recruiting → Active not recruiting | Phase 2 | Yale University |
| Lacticaseibacillus Rhamnosus LRa05 for Alleviating Allergic Rhinitis probiotic product, Maltodextrin | Not yet recruiting → Completed | Not applicable | Wecare Probiotics Co., Ltd. |
| Research on the Use of Probiotics in the Prevention and Treatment of Inflammatory Bowel Disease Probiotic | Recruiting → Completed | Not applicable | Wecare Probiotics Co., Ltd. |
| A Study of Botensilimab (AGEN1181) for the Treatment of Advanced Melanoma Botensilimab, Balstilimab | Active not recruiting → Terminated Sponsor decision | Phase 2 | Agenus Inc. |
| Intranasal Insulin and Olanzapine Study in Healthy Volunteers OLANZapine 2.5 MG, Placebo, Insulin Lispro 100 UNT/ML | Active not recruiting → Completed | Phase 1 | Centre for Addiction and Mental Health |
| A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202) cyclosporine, Matched Unrelated Donor Hematopoetic Stem Cell Transplant, horse anti-thymocyte globulin (ATG) | Active not recruiting → Terminated Funding terminated | Phase 3 | Boston Children's Hospital |
| 24VA021; VATCH Trametinib for Ras/MAPK Pathway VAs Trametinib | Active not recruiting → Recruiting | Phase 2 | Children's Hospital of Philadelphia |
| Ketamine Biomarker Validation Ketamine (0.25 mg/kg), Ketamine (0.5 mg/kg), Ketamine (0.75 mg/kg) | Not yet recruiting → Withdrawn Funding was not provided | Phase 1 | Soterix Medical |
| Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy Anticoagulant Therapy, Catheter-Directed Therapy | Recruiting → Active not recruiting | Phase 3 | NYU Langone Health |
| Evaluating Simplified Layered Consent for Clinical Trials Simplified layered consent form, Full-length consent form | Recruiting → Completed | Not applicable | Sunnybrook Health Sciences Centre |
| Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases Lumoral Treatment, Standard, personalized oral health care | Recruiting → Completed | Not applicable | Wellbeing Services County of Pirkanmaa |
| MRG003 Induction and Capecitabine Maintenance With PD-1 in Locally Recurrent NPC MRG003, Tislelizumab, Capecitabine | Not yet recruiting → Recruiting | Phase 2 | Fujian Cancer Hospital |
| The Norwegian Trial of Physical Exercise After Myocardial Infarction Physical exercise, Standard care, Observation group | Enrolling by invitation → Active not recruiting | Not applicable | Norwegian University of Science and Technology |
| Study of the Efficacy of Dietary Supplementation in Targeting Sleep Quality (NutriSom-01B) 21 days of intervention with Placebo Product (PP), 21 days of intervention with Active Control (AC), 21 days of intervention with Test Product (TP) | Not yet recruiting → Completed | Not applicable | Institute of Nutrition, Slovenia (Nutris) |
| Ultrasound for Diagnosing Costochondral Joint Separation Ultrasound (USG) | Not yet recruiting → Completed | Not applicable | Caner İşevi, MD |
| Lupus Nephritis Care Pathway Lupus Nephritis (LN) Care Pathway | Not yet recruiting → Recruiting | Not applicable | Duke University |
| Educational Eczema Video Intervention in-clinic video intervention, at home video intervention | Not yet recruiting → Withdrawn never obtained funding | Not applicable | Boston Children's Hospital |
| A Study to Evaluate the Safety,Pharmacokinetics,Pharmacodynamics,and Efficacy of TJ037130 in Adult Participants With Advanced Solid Tumors TJ037130 | Not yet recruiting → Recruiting | Phase 1 | TJ Biopharma Co., Ltd. |
| ACB With S-ESPB Versus ACB With iPACK for Knee Arthroplasty Adductor Canal Block, Sacral Erector Spinae Plane Block, iPACK Block | Recruiting → Completed | Not applicable | Poznan University of Medical Sciences |
| SHAPE Test for Preoperative Risk Stratification Shape II | Recruiting → Active not recruiting | Yale University | |
| Effects of the 4-7-8 Breathing Technique on Postoperative Pain Scores, Anxiety, and Sleep Quality in Patients 4-7-8 Breathing Technique | Not yet recruiting → Completed | Not applicable | Konya Beyhekim Training and Research Hospital |
| Pilot Investigation to Evaluate FlowOx2.0™ for Experimental Treatment of Spasticity FlowOx™ | Unknown → Completed | Not applicable | Otivio AS |
| Effects of 8 Weeks of Turmeric Ingestion on Physiology and Wellbeing in Healthy Older Adults Raw turmeric shots, Placebo | Recruiting → Completed | Not applicable | Nottingham Trent University |
| Feasibility Study Comparing One vs Two Probes for Thermal Ablation Among Cervical Cancer Screen Positive Women Living With HIV in C1001P-CS7 Zimbabwe Thermal ablation (TA) with 1 probe, Thermal ablation (TA) with 2 probes | Not yet recruiting → Recruiting | Not applicable | Fred Hutchinson Cancer Center |
| Immunotherapy and Nodal-Sparing Irradiation for T-Cell Induction and Unmasking of Tumor Antigenicity in the Microenvironment for Head and Neck Cancer Pembrolizumab, Radiotherapy, ENI | Not yet recruiting → Recruiting | Phase 2 | Medical College of Wisconsin |
| Slow Wave Sleep as a Biomarker of Rehabilitation-induced Cognitive Improvement in PD Progressive Resistance Training (PRT), Delayed Exercise Training (DE), Endurance Training (ET) | Unknown → Active not recruiting | Not applicable | University of Colorado, Denver |
| Prophylactic Transfusion In Pregnant in Women With Sickle Cell Disease Prophylactic Transfusion Intervention group: Transfusion, Control group | Recruiting → Withdrawn The study was withdrawn due to no enrollment | Phase 4 | Emory University |
| An Observational Study to Learn How Mirena and Other Progestogen Treatments Are Used for Endometrial Protection in Women 40+ With a Uterus in the United States Receiving Estrogen Therapy, and Their Respective Health Outcomes Estrogen therapy, Mirena levonorgestrel-releasing intrauterine system, Other progestogen therapy | Not yet recruiting → Active not recruiting | Bayer | |
| A Study of IBI3046 in Participants With Overweight or Obesity IBI3046, placebo | Not yet recruiting → Recruiting | Phase 1 | Innovent Biologics (Suzhou) Co. Ltd. |
| Performance and Long-term Safety of FlowOx2.0™ in Patients With Multiple Sclerosis - Impact on Spasticity and Pain FlowOx 2.0, FlowOx2.0 (Sham) | Unknown → Completed | Not applicable | Otivio AS |
| AVEIR DR Coverage With Evidence Development (CED) Study Aveir DR Leadless Pacemaker System, Dual Chamber Transvenous Pacemaker | Recruiting → Active not recruiting | Abbott Medical Devices | |
| Super Chef - an Online Program Promoting the Mediterranean Dietary Pattern to Lower Income Families Super Chef: Family Fun in the Kitchen! | Active not recruiting → Completed | Not applicable | Baylor College of Medicine |
| A Preliminary Study on the Efficacy of Danggui Shaoyao San and Cuscuta Chinensis in Patients With Primary Dysmenorrhea Danggui Shaoyao San (DSS), Cuscuta Chinensis (Tu Si Zi), Combination Therapy (DSS + Tu Si Zi) | Unknown → Terminated The study was stopped early before reaching the planned enrollment of 200 participants because the allocated research budget was exhausted and additional study medication could not be funded. Enrollment will not resume. | Not applicable | Taichung Tzu Chi Hospital |
| Effectiveness of a Home-Based Exercise Program Supported by Self-Management Education in People With Parkinson Disease Self-Management Education and Home Exercise Program, Parkinson Disease Educational Booklet | Not yet recruiting → Active not recruiting | Not applicable | Istanbul University |
| Personal Health Train for Radiation Oncology in India and The Netherlands | Active not recruiting → Completed | Maastricht Radiation Oncology | |
| Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer Domvanalimab, Zimberelimab, Carboplatin | Active not recruiting → Completed | Phase 2 | Arcus Biosciences, Inc. |
| Nebulized Ketamine Plus Standard Care vs. Standard Care Alone in Moderate to Severe Asthma Exacerbations Nebulized ketamine (0.5 mg/kg in normal saline to a total volume of 5ml) plus standard asthma excaerbationcare, Placebo nebulization (5 mL normal saline) plus standard asthma care | Not yet recruiting → Recruiting | Phase 2 | Oman Medical Speciality Board |
| Continuous Versus Intermittent Enteral Feeding and Gastric Residual Volume in Critically Ill Patients Continuous Enteral Feeding, Intermittent Enteral Feeding | Not yet recruiting → Recruiting | Not applicable | Viet Duc University Hospital |
| Scapular Stabilization Versus Proprioceptive Neuromuscular Facilitation Technique in Scapular Dyskinesis Scapular Stabilization Exercises+ Proprioceptive Neuromuscular Facilitation, Patient engagement through warm-up and Scapular Stabilization exercises | Enrolling by invitation → Active not recruiting | Not applicable | University of Lahore |
| Leniolisib for Immune Dysregulation in PIDs Leniolisib | Active not recruiting → Completed | Phase 2 | Pharming Technologies B.V. |
| Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53) WVE-N531 | Recruiting → Active not recruiting | Phase 1 / Phase 2 | Wave Life Sciences USA, Inc. |
| ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency INZ-701 | Active not recruiting → Terminated The study was terminated by the sponsor prior to planned completion based on a review of the data across indications and overall program considerations. Study termination was not related to participant safety. | Phase 2 | Inozyme Pharma |
| RESET-COPD Cohort: Real-Time Monitoring and Early Warning in COPD Patients Receiving Home NPPV Not applicable- observational study | Enrolling by invitation → Recruiting | Beijing Chao Yang Hospital | |
| A Phase 1b/2 Multisite Dose-finding and Expansion Study of WTX-330 in Adult Patients With Selected Advanced or Metastatic Solid Tumors or Lymphoma WTX-330 | Active not recruiting → Completed | Phase 1 / Phase 2 | Werewolf Therapeutics, Inc. |
| Piloting a School-Based Distress Tolerance Skills Program for Adolescents Distress Tolerance Skills Training | Active not recruiting → Completed | Not applicable | Oregon Health and Science University |
| Evaluation of a Supervised Clinical Feeding Intervention Supervised feeding intervention, Handout | Not yet recruiting → Withdrawn no funding | Not applicable | Boston Children's Hospital |
| Pediatrics Mobile CT Mobile CT | Recruiting → Completed | Not applicable | Duke University |
| Medication Use and Quality of Life Among Older People Deprescribing intervention | Active not recruiting → Completed | Not applicable | Odense University Hospital |
| 24VA022; VATCH Alpelisib for TIE2/PIK3CA Pathway VAs alpelisib (BYL719) | Active not recruiting → Recruiting | Phase 2 | Children's Hospital of Philadelphia |
| Effects of Cytotoxic Chemotherapy and PARP Inhibition on the Genomic Contexture of Ovarian Cancer | Unknown → Completed | Hellenic Cooperative Oncology Group | |
| Previfenon® as Chemoprophylaxis of COVID-19 in Health Workers Previfenon®, Placebo | Unknown → Withdrawn The protocol was withdrawn because enrollment did not begin. | Phase 2 / Phase 3 | MELISA Institute Genomics & Proteomics Research SpA |
| Bedside Spirometry for Acute Lung Injury Hand-held spirometer, NIV | Not yet recruiting → Recruiting | Not applicable | Centre Hospitalier Departemental Vendee |
| Smart Underwear to Measure Diet-Induced Hydrogen Sulfide Production High Cysteine Diet, Low Cysteine Diet | Recruiting → Completed | Not applicable | University of Colorado, Denver |
| Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer PET-directed Local Therapy using Surgery, PET-directed Local Therapy using Radiation, Salvage Local Therapy for locally recurrent disease | Recruiting → Active not recruiting | Phase 2 / Phase 3 | VA Office of Research and Development |
| Mortality and Muscle Mass Loss in Critically Ill Patients. | Not yet recruiting → Recruiting | Brno University Hospital | |
| Naturally Banded Versus Synthetic Banding of Sleeve Gastrectomy natural band, silicone band | Unknown → Completed | Not applicable | Minia University |
| Light Therapy in End Stage Kidney Disease Bright light, Dim Light | Active not recruiting → Completed | Not applicable | University of Pennsylvania |
| BXCL701 Phase 1 R/R Acute Myeloid Leukemia or Myelodysplastic Syndrome BXCL701 | Recruiting → Active not recruiting | Phase 1 | Eric Stephen Winer, MD |
| Video Education With Result Dependent dIsclosure Video Education, Genetic Counseling | Recruiting → Completed | Not applicable | Dana-Farber Cancer Institute |
| A Study to Evaluate the Cariostatic Efficacy of Nano Silver Fluoride (NSF) vs. Silver Diamine Fluoride (SDF) in Children Nano Silver Fluoride / NSF | Not yet recruiting → Recruiting | Not applicable | A.T. Still University of Health Sciences |
| Ambient AI for Reducing Nursing Staff Documentation Time Artificial Intelligence | Recruiting → Active not recruiting | Not applicable | University of Wisconsin, Madison |
| QLS31905 in Combination With CAPOX Versus Sintilimab in Combination With CAPOX as First-line Treatment in Patients With GC/GEJ QLS31905, Sintilimab, Oxaliplatin | Not yet recruiting → Recruiting | Phase 3 | Qilu Pharmaceutical Co., Ltd. |
| Consumer Health Study Aims to Evaluate the Safety, Tolerability and Impact of ED02 Probiotic Supplement on Gastrointestinal Outcomes Bifidobacterium pseudocatenulatum, Placebo | Active not recruiting → Completed | Not applicable | Synbiotic Health |
| A Study Of Auricular Transcutaneous Vagus Nerve Stimulation In Chronic Dizziness Sham Device, Auricular transcutaneous vagus nerve stimulation | Recruiting → Enrolling by invitation | Not applicable | Mayo Clinic |
| Efficacy of Genicular Block on Total Knee Arthroplasty Surgery Genicular blocks (bupivakain), placebo injection with 0.9% sodium chloride, Paracetamol (acetaminophen)+diclofenac | Not yet recruiting → Completed | Not applicable | Mersin University |
| A Study to Learn How Men With Advanced Prostate Cancer Respond to Treatment With Darolutamide and Hormone Therapy, With or Without Chemotherapy, in Real-world Medical Practice Darolutamide (BAY 1841788), ADT, Docetaxel | Active not recruiting → Recruiting | Bayer | |
| 3rd Generation Resorbable Magnesium Scaffolds vs Biodegradable Polymer Stents in NSTE/ACS Percutaneous coronary intervention | Not yet recruiting → Withdrawn No funding | Not applicable | Konstantinos Toutouzas |
| Software as a Medical Device for the Treatment of Patients With PTSD Software as a Medical Device | Recruiting → Active not recruiting | Phase 2 / Phase 3 | Otsuka Medical Devices Co., Ltd. Japan |
| Melanoma: Genomic Profiles, Molecular Markers and Therapeutic Implications | Unknown → Active not recruiting | Hellenic Cooperative Oncology Group | |
| Trastuzumab Rezetecan and Adebrelimab as Neoadjuvant Therapy for HER2-Positive Muscle-Invasive Bladder Cancer Trastuzumab Rezetecan Combined with Adebelizumab | Not yet recruiting → Active not recruiting | Phase 2 | Harbin Medical University |
| The RIPPLE AT-PLUS Study Catheter ablation of atrial tachycardia: Ripple Mapping guided., Catheter ablation of atrial tachycardia: Conventional mapping guided. | Active not recruiting → Completed | Not applicable | Liverpool Heart and Chest Hospital NHS Foundation Trust |
| CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER) CB-010, Cyclophosphamide, Fludarabine | Unknown → Active not recruiting | Phase 1 | Caribou Biosciences, Inc. |
| Dupilumab De-escalation in Pediatric Atopic Dermatitis Dupilumab - Discontinuation, Dupilumab - Dose Reduction, Dupilumab - Standard Dose | Recruiting → Terminated Poor accrual | Phase 4 | Johns Hopkins University |
| Aveir VR Coverage With Evidence Development Post-Approval Study Aveir VR Leadless Pacemaker System, Single-Chamber Transvenous Pacemaker | Recruiting → Active not recruiting | Abbott Medical Devices | |
| Unmet Needs, Barriers and Facilitators to Vision Services for Children and Adolescents With Special Vision observational study, no intervention | Enrolling by invitation → Completed | National Taiwan University Hospital | |
| Effects of Ankle Evertor Fatigue on Perturbed Gait Muscle fatigue | Recruiting → Completed | University of Ljubljana | |
| Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) Immune Kidney Transplant Study (COVID-19) SARS-CoV-2 vaccine | Unknown → Completed | Oslo University Hospital | |
| Music Mindfulness Study 2a. in person meditation, in person meditation using headphones, virtual meditation | Recruiting → Completed | Not applicable | Yale University |
| A Study With CIT-013 in RA Patients CIT-013 low dose, CIT-013 high dose, Placebo | Recruiting → Completed | Phase 2 | Citryll BV |
| KN035 for dMMR/MSI-H Advanced Solid Tumors KN035 | Recruiting → Active not recruiting | Phase 2 | 3D Medicines (Sichuan) Co., Ltd. |
| Comparison of the Effects of External Oblique Intercostal Plane Block and Subcostal Transversus Plane Block Methods With Ultrasound Guidance on Postoperative Analgesia in Laparoscopic Sleeve Gastrectomy Operations Ultrasound-guided external oblique intercostal plane block, Local anesthetic infiltration, Subcostal Transversus Abdominis Plane Block (s-TAP) | Not yet recruiting → Completed | Not applicable | Sanliurfa Education and Research Hospital |
| A Study to Learn About the Safety of BIIB147 and Its Effects in Adults With Amyotrophic Lateral Sclerosis (ALS) BIIB147, Placebo | Not yet recruiting → Recruiting | Phase 1 / Phase 2 | Biogen |
| CARdiAc Mri and BiOLogical samplEs at the Acute Phase of a Myocardial Infarction (CARAMBOLE) Blood, urinary and feces collection, Cardiac MRI, Quality of life and cognitive status questionnaire | Active not recruiting → Completed | Not applicable | Poitiers University Hospital |
| Effect of Periumbilical Vibration on Pain Perception During Intrauterine Device Insertion: A Randomized Controlled Trial Periumbilical Vibration during Intrauterine Device Placement | Not yet recruiting → Recruiting | Not applicable | Duke University |
| Performance and Long-term Safety of FlowOx2.0™, Multiple Sclerosis, Spasticity and Pain FlowOx 2.0 | Unknown → Completed | Not applicable | Otivio AS |
| Prescribed Knee Brace Treatments for Osteoarthritis of the Knee (Knee OA) This is a non interventional registry | Enrolling by invitation → Recruiting | Össur Iceland ehf | |
| Window Trial of Intratumoral (IT) Neoadjuvant Fluorescently Labelled Nivolumab (nivo800) in Head and Neck Squamous Cell Carcinoma (HNSCC) Nivolumab-IRDye800 | Not yet recruiting → Recruiting | Early Phase 1 | Vanderbilt-Ingram Cancer Center |
| Effects of Ankle Evertor Fatigue on Force Sense and Neuromuscular Activation in Subjects With Chronic Ankle Instability | Recruiting → Completed | University of Ljubljana | |
| Neurophysiological Benefits of Live Music for Early Alzheimer's Patients and Their Caregivers Pre-recorded Music Session, Live Music Session | Active not recruiting → Completed | Not applicable | Yale University |
| A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes Orforglipron, Dulaglutide | Not yet recruiting → Recruiting | Phase 3 | Eli Lilly and Company |
| Basal Cell Carcinoma Chemoprevention Trial 5% Imiquimod cream, Placebo Vehicle Control Cream | Not yet recruiting → Recruiting | Phase 3 | VA Office of Research and Development |
| A Study to Learn About How a New Nurandociguat Tablet is Absorbed and Processed in the Body Compared to an Old Tablet and How Food Affects the Way the New Tablet is Absorbed and Processed in the Body Nurandociguat (BAY3283142) old tablet - SD, Nurandociguat (BAY3283142) new tablet - SD, Nurandociguat (BAY3283142) old tablet | Recruiting → Completed | Phase 1 | Bayer |
| CREDE Study: Intraoperative Crede Manoeuver Compared to Preoperative Prolapse Reduction Stress Test to Predict Postoperative de Novo Stress Urinary Incontinence (PONSUI) at the Time of Pelvic Organ Prolapse (POP) Surgery Intraoperative Crede manoeuver, Preoperative prolapse reduction cough stress test | Unknown → Terminated Prolonged slow recruitment | Not applicable | McGill University Health Centre/Research Institute of the McGill University Health Centre |
| Real World Data Analysis of PARP Inhibitors Use in Patients With Ovarian Cancer PARP inhibitor | Unknown → Completed | Hellenic Cooperative Oncology Group | |
| Finnish Venous Ulcer Study (FINNULCER Study) Endothermal Ablation, Foam Sclerotherapy | Recruiting → Completed | Not applicable | Oulu University Hospital |
| A Phase 1 Relative Bioavailability Study of a VX-581 Tablet Formulation VX-581 | Not yet recruiting → Recruiting | Phase 1 | Vertex Pharmaceuticals Incorporated |
| Hearing Outcomes With the Nucleus® 8 Sound Processor and Nucleus® 7 Sound Processor in Adult Veteran and Non-veteran Cochlear Implant Recipients Nucleus 7 Sound Processor, Nucleus 8 Sound Processor | Not yet recruiting → Completed | Not applicable | Cochlear |
| PET-Based Imaging of Radiolabeled CIT-013 [89Zr]Zr-CIT | Recruiting → Completed | Phase 2 | Citryll BV |
| Cannabis Association With Sleep Study Manipulation of Sleep Duration | Not yet recruiting → Recruiting | Not applicable | Oregon Health and Science University |
| MagnetisMM-3: Study Of Elranatamab (PF-06863135) Monotherapy in Participants With Multiple Myeloma Who Are Refractory to at Least One PI, One IMiD and One Anti-CD38 mAb Elranatamab (PF-06863135) | Active not recruiting → Completed | Phase 2 | Pfizer |
| Photobiomodulation for the Prevention of Radiation Induced Oral Mucositis Photobiomodulation | Unknown → Active not recruiting | Not applicable | Ottawa Hospital Research Institute |
| Immunogenicity and Safety Study of an Investigational Quadrivalent Meningococcal Conjugate Vaccine Administered in Healthy Children and Adolescents in China MenACYW conjugate vaccine, MenACYW135 polysaccharide vaccine, MenAC conjugate vaccine | Active not recruiting → Completed | Phase 3 | Sanofi |
| The Effect of Dexamethasone Administration Route and Local Anesthetic Concentration on Pain, Inflammatory Response, and Neuromonitoring in Children Undergoing Scoliosis Correction perineural Dexamethasone, intravenous Dexamethasone | Recruiting → Completed | Phase 4 | Poznan University of Medical Sciences |
| Body-oriented Psychotherapy for Individuals With a History of Child Maltreatment and Trauma-related Symptoms SE-group, Control | Recruiting → Active not recruiting | Not applicable | Monique Pfaltz |
A trial with several areas is listed under each.