The Effects of Different Educational Methods Given to Patients Undergoing Organ Transplantation on Quality of Life, Compliance With İmmunosuppressive Therapy and Symptom Control
| Registry | NCT07288918 |
|---|---|
| Status | Recruiting |
| Phase | Not applicable |
| Study type | Interventional; randomized, parallel, masking: double, supportive care |
| Enrollment | 108 (Estimated) |
| Sponsor | Ondokuz Mayıs University (Other) |
| Conditions | Organ Transplantation, Mobile Applications, Nursing |
| Interventions | Mobile application installation, Providing teaching booklets, Control (Other) |
| Dates | start 2025-12-10, primary completion 2027-01-01 (estimated), completion 2027-05-30 (estimated), first posted 2025-12-17, last updated 2026-10-21 |
| Locations | 1 site in Turkey (Türkiye) |
Related Papers Related Patents Related Grants Related Experts
All trials for Organ Transplantation All trials for Mobile Applications All trials of Mobile application installation All trials of Providing teaching booklets
Organ transplantation is the most effective method for treating end-stage organ failure and allows patients on the verge of death to continue living. Organ transplantation involves removing all or part of an organ or tissue from the body and transplanting it to suitable patients experiencing failure. Therefore, transplants are performed to treat diseases, save lives, improve patients' quality of life, and extend their life expectancy. The World Health Organization (WHO) defines quality of life as individuals' perceptions of their goals, expectations, standards, and concerns regarding their place in life, within the context of the culture and value systems they live in. Achieving an adequate quality of life after transplantation is considered an indicator of therapeutic success, which is increasingly important to measure by the transplant care team.
Individuals who undergo transplantation and their families often perceive transplantation as a rebirth. However, 30% to 40% of patients report no better health-related quality of life after kidney transplantation compared to dialysis. This is attributed to frequent checkups and monitoring, new medications and their strict dosing schedules, and the unexpected discomfort of potential side effects.
Even after the psychological challenges of waiting and the joy of a successful transplant, transplant recipients take on new responsibilities. Problems such as accepting transplantation risks, acute and chronic organ rejection, and adherence to lifelong medication regimens can arise. Persistent side effects of various immunosuppressive agents, adaptation and maintenance of the new organ, and uncertainty about the future due to rejection of transplanted organs and the subsequent re-transplantation process can all lead to physical and psychological distress.
Immunosuppressive therapy represents a lifelong endeavor for transplant recipients. These medication regimens involve complex protocols, not only due to the number of pills required, but also due to blood level monitoring, side effects, and frequent dose adjustments to avoid rejection. Non-adherence to immunosuppressant regimens has been shown to be high in organ transplant patients. Non-adherence rates in this population are reported as high as 65%. The highest immunosuppressant non-adherence rate is found in kidney transplant recipients, with a prevalence of 36-55%, while this rate is 15-40% in liver transplant recipients. Studies have found that 16-36% of graft losses are associated with non-adherence. The ever-growing population of transplant recipients and the limited number of transplant centers, particularly those living farther away, necessitate innovative healthcare delivery models to monitor and improve the use of transplant center resources. With the advent of smartphones and mobile medical devices, mobile health has become a popular way for healthcare professionals to manage patient care. Mobile health can serve as an adjunct method for delivering health education information, sending reminders to patients to take their medications, and implementing online education. In particular, converting paper-based education to video format can significantly increase knowledge on various topics. It is necessary to address the problems and challenges patients face after discharge and the practices that can potentially address these issues. These results suggest that healthcare professionals can do more to provide comprehensive care to patients, promote successful home-based treatment regimens, symptom control, and quality of life.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| Mobile applications | Experimental | Other: Mobile application installation | |
| Teaching booklet | Experimental | Other: Providing teaching booklets | |
| Control | Active comparator | Other: Control |
Sex: All, ages: 18 Years to any
Inclusion Criteria: * Being over 18 years of age, * Having undergone a liver or kidney transplant for the first time, * Having been discharged at least three months ago, * Having access to a smartphone and internet and the ability to use them independently, Exclusion Criteria: * Having a diagnosis of a psychiatric or neurological disorder, * Having hearing or vision problems severe enough to impede communication, * Requesting to leave during the research period
| Facility | City | Country | Status |
|---|---|---|---|
| Ondokuz Mayis University | Samsun, Samsun | Turkey (Türkiye) | Recruiting |