7 completed, 2 recruiting, 1 active not recruiting, 1 terminated. 7 Phase 2, 6 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 5, Active not recruiting 1, Recruiting 1 |
| Phase 3 | 6 | Completed 3, Recruiting 2, Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation Research Privosegtor, Methylprednisolone, Placebo - Optic Neuritis | Phase 3 | Recruiting | Oculis | 210 | 2026-05-28 | 2026-08-14 |
| A Clinical Study Evaluating Licaminlimab for Dry Eye Disease Artificial Tear Run-in, licaminlimab, Vehicle of licaminlimab - Dry Eye Disease (DED) | Phase 2 / Phase 3 | Recruiting | Oculis | 160 | 2026-04-16 | 2026-08-28 |
| A Pivotal Safety and Efficacy Study of OCS-01 Eye Drops in Participants With Diabetic Macular Edema (DIAMOND 2) Dexamethasone ophthalmic suspension (OCS-01), Vehicle - Diabetic Macular Edema | Phase 3 | Completed | Oculis | 401 | 2024-03-15 | 2026-05-01 |
| A Phase 3 Study Evaluating the Efficacy and Safety of OCS-01 Opthalmic Suspension Compared to Vehicle for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery OCS-01, Vehicle - Inflammation Eye Pain, Postoperative Cataract | Phase 3 | Terminated | Oculis | 117 | 2023-12-18 | 2026-07-30 |
| Safety and Efficacy of Licaminlimab Ophthalmic Solution for the Treatment of Dry Eye Disease licaminlimab, vehicle of OCS-02, Artificial tears - Dry Eye Disease | Phase 2 | Completed | Oculis | 122 | 2023-11-29 | 2025-07-02 |
| Multicenter Study on the Efficacy and Safety of OCS-01 in Subjects With Uveitis Related and Post Surgical Macular Edema OCS-01 - Uveitis Related Cystoid Macular Edema, Cystoid Macular Edema, Postoperative | Phase 2 | Active not recruiting | Quan Dong Nguyen | 28 | 2023-05-26 | 2025-05-25 |
| A Phase 3 Study Evaluating the Efficacy and Safety of OCS-01 Eyedrops Compared to Vehicle for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery OCS-01, Vehicle - Inflammation Eye Pain, Postoperative Cataract | Phase 3 | Completed | Oculis | 241 | 2022-06-24 | 2025-07-11 |
| A Pivotal Safety and Efficacy Study of OCS-01 Eye Drops in Participants With Diabetic Macular Edema (DIAMOND 1) Dexamethasone ophthalmic suspension (OCS-01), Vehicle - Diabetic Macular Edema | Phase 2 / Phase 3 | Completed | Oculis | 552 | 2021-10-19 | 2026-05-05 |
| OCS-05 in Patients With Optic Neuritis OCS-05 +SoC (corticosteroid) IV administration, Placebo + SoC (corticosteroid) IV administration - Optic Neuritis | Phase 2 | Completed | Oculis | 36 | 2021-02-10 | 2025-09-22 |
| OCS-01 in Treating Inflammation and Pain in Post-cataract Patients OCS-01 - Dexamethasone Cyclodextrin Nanoparticle Ophthalmic Suspension 1.5% mg/mL, Placebo - Inflammation Corneal, Pain, Postoperative | Phase 2 | Completed | Oculis | 153 | 2019-09-27 | 2025-09-10 |
| Efficacy and Safety of Dexamethasone Nanoparticles Eye Drops in Diabetic Macular Edema Dexamethasone nanoparticles eye drops - Diabetic Macular Edema | Phase 2 | Completed | Oculis | 144 | 2017-09-18 | 2022-06-28 |
Dry Eye Syndromes (2) · Optic Neuritis (2) · Inflammation (1) · Keratitis (1) · Macular Edema (1) · Multiple Sclerosis (1) · Optic Nerve Diseases (1) · Pain (1) · Pain, Postoperative (1) · Retinal Diseases (1) · Uveitis (1) · Vision Disorders (1)
Dexamethasone (2) · Adrenal Cortex Hormones (1) · Lubricant Eye Drops (1) · Methylprednisolone (1) · Organization and Administration (1)
United States (9) · India (2) · Argentina (1) · Denmark (1) · France (1) · Hong Kong (1) · Puerto Rico (1) · Taiwan (1)
Sharon Klier, MD, MPH (2) · Diana Do, MD (1) · Michael Larsen, MD (1) · Quan D Nguyen, MD, MSc (1) · Veeral S Sheth, MD (1)