Medivation, Inc.: Clinical Trials

13 trials sponsored by Medivation, Inc., newest first

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6 terminated, 5 completed, 1 unknown, 1 withdrawn. 13 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 313Terminated 6, Completed 5, Unknown 1, Withdrawn 1

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Trials (filtered) newest first · largest first

All 13 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Efficacy and Safety Study of Enzalutamide in Combination With Paclitaxel Chemotherapy or as Monotherapy Versus Placebo With Paclitaxel in Patients With Advanced, Diagnostic-Positive, Triple-Negative Breast Cancer
Enzalutamide, Placebo, Paclitaxel - Breast Cancer
Phase 3WithdrawnPfizer2016-09-012018-10-22
Enzalutamide With or Without Abiraterone and Prednisone in Treating Patients With Castration-Resistant Metastatic Prostate Cancer
enzalutamide, abiraterone, prednisone - Adenocarcinoma of the Prostate, Hormone-resistant Prostate Cancer
Phase 3UnknownAlliance for Clinical Trials in Oncology13112014-01-222023-09-28
A Study Evaluating Talazoparib (BMN 673), a PARP Inhibitor, in Advanced and/or Metastatic Breast Cancer Patients With BRCA Mutation (EMBRACA Study)
talazoparib, Physician's-Choice - Breast Neoplasms, BRCA 1 Gene Mutation
Phase 3CompletedPfizer4312013-10-142022-01-20
An Extension of the CONCERT Protocol (DIM18)
Dimebon - Alzheimer's Disease
Phase 3TerminatedMedivation, Inc.6722010-04-012016-09-27
An Extension To The B1451006 Protocol To Evaluate The Safety and Efficacy of Dimebon In Subjects With Moderate-to-Severe Alzheimer's Disease
Dimebon tablet for oral administration - Alzheimer's Disease
Phase 3TerminatedPfizer52010-04-012012-10-02
An Extension of the HORIZON Protocol Evaluating the Safety of Dimebon (Latrepirdine) in Subjects With Huntington Disease
Dimebon (latrepirdine) - Huntington Disease
Phase 3TerminatedMedivation, Inc.3622010-02-012016-10-12
A Safety and Efficacy Study Evaluating Dimebon (Latrepirdine) in Patients With Moderate to Severe Alzheimer's Disease
Dimebon (latrepirdine), Placebo - Moderate to Severe Alzheimer
Phase 3TerminatedMedivation, Inc.892009-10-012016-09-27
An Extension To The B1451027 Protocol To Evaluate The Long Term Safety And Tolerability Of Dimebon In Patients With Alzheimer's Disease
Dimebon - Alzheimer's Disease
Phase 3TerminatedPfizer6492009-09-012012-11-14
A Phase 3 Efficacy Study Of Dimebon In Patients With Moderate To Severe Alzheimer's Disease
Dimebon 20 mg po TID, Placebo po TID - Alzheimer Disease
Phase 3TerminatedPfizer862009-09-012012-10-02
A Safety and Efficacy Study of Dimebon in Patients With Huntington Disease
Dimebon, Placebo - Huntington Disease
Phase 3CompletedMedivation, Inc.4032009-07-012016-10-12
Safety and Efficacy Study Evaluating Dimebon in Patients With Mild to Moderate Alzheimer's Disease on Donepezil
Dimebon, Placebo comparator - Alzheimer's Disease
Phase 3CompletedMedivation, Inc.10032009-03-012016-09-27
A Phase 3 Study To Evaluate The Safety And Tolerability Of Dimebon Patients With Mild To Moderate Alzheimer's Disease
Dimebon, Placebo - Alzheimer's Disease
Phase 3CompletedPfizer7422009-02-012018-12-06
A Safety and Efficacy Study of Oral Dimebon in Patients With Mild-To-Moderate Alzheimer's Disease
Dimebon, Placebo - Alzheimer's Disease
Phase 3CompletedMedivation, Inc.5982008-05-012016-09-27

Conditions studied

Alzheimer Disease (7)  ·  Dementia (3)  ·  Breast Neoplasms (2)  ·  Huntington Disease (2)  ·  Memory Disorders (2)  ·  Neurodegenerative Diseases (2)  ·  Central Nervous System Diseases (1)  ·  Cognitive Dysfunction (1)  ·  Delirium (1)  ·  Mental Disorders (1)  ·  Neoplasm Metastasis (1)  ·  Nervous System Diseases (1)  ·  Prostatic Neoplasms (1)

Interventions

latrepirdine (10)  ·  enzalutamide (2)  ·  Administration, Oral (1)  ·  Paclitaxel (1)  ·  Prednisone (1)  ·  abiraterone (1)  ·  talazoparib (1)

Countries

United States (10)  ·  Canada (5)  ·  Germany (4)  ·  United Kingdom (4)  ·  Australia (3)  ·  Puerto Rico (3)  ·  Belgium (2)  ·  France (2)  ·  Italy (2)  ·  Spain (2)  ·  Sweden (2)  ·  Brazil (1)  ·  Chile (1)  ·  Denmark (1)  ·  Finland (1)

Top investigators

Lynn Seely, MD (1)  ·  Michael Morris, M.D. (1)

Results publications

PMID 23108692, PMID 30110579, PMID 30124753, PMID 35091441, PMID 36996380, PMID 39663356, PMID 41346252

NIH funding

2016 (1), U10CA031946 (1)