6 terminated, 5 completed, 1 unknown, 1 withdrawn. 13 Phase 3.
By phase and status
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Trials (filtered) newest first · largest first
All 13 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
Efficacy and Safety Study of Enzalutamide in Combination With Paclitaxel Chemotherapy or as Monotherapy Versus Placebo With Paclitaxel in Patients With Advanced, Diagnostic-Positive, Triple-Negative Breast Cancer Enzalutamide, Placebo, Paclitaxel - Breast Cancer | Phase 3 | Withdrawn | | 2016-09-01 | 2018-10-22 |
Enzalutamide With or Without Abiraterone and Prednisone in Treating Patients With Castration-Resistant Metastatic Prostate Cancer enzalutamide, abiraterone, prednisone - Adenocarcinoma of the Prostate, Hormone-resistant Prostate Cancer | Phase 3 | Unknown | 1311 | 2014-01-22 | 2023-09-28 |
A Study Evaluating Talazoparib (BMN 673), a PARP Inhibitor, in Advanced and/or Metastatic Breast Cancer Patients With BRCA Mutation (EMBRACA Study) talazoparib, Physician's-Choice - Breast Neoplasms, BRCA 1 Gene Mutation | Phase 3 | Completed | 431 | 2013-10-14 | 2022-01-20 |
An Extension of the CONCERT Protocol (DIM18) Dimebon - Alzheimer's Disease | Phase 3 | Terminated | 672 | 2010-04-01 | 2016-09-27 |
An Extension To The B1451006 Protocol To Evaluate The Safety and Efficacy of Dimebon In Subjects With Moderate-to-Severe Alzheimer's Disease Dimebon tablet for oral administration - Alzheimer's Disease | Phase 3 | Terminated | 5 | 2010-04-01 | 2012-10-02 |
An Extension of the HORIZON Protocol Evaluating the Safety of Dimebon (Latrepirdine) in Subjects With Huntington Disease Dimebon (latrepirdine) - Huntington Disease | Phase 3 | Terminated | 362 | 2010-02-01 | 2016-10-12 |
A Safety and Efficacy Study Evaluating Dimebon (Latrepirdine) in Patients With Moderate to Severe Alzheimer's Disease Dimebon (latrepirdine), Placebo - Moderate to Severe Alzheimer | Phase 3 | Terminated | 89 | 2009-10-01 | 2016-09-27 |
An Extension To The B1451027 Protocol To Evaluate The Long Term Safety And Tolerability Of Dimebon In Patients With Alzheimer's Disease Dimebon - Alzheimer's Disease | Phase 3 | Terminated | 649 | 2009-09-01 | 2012-11-14 |
A Phase 3 Efficacy Study Of Dimebon In Patients With Moderate To Severe Alzheimer's Disease Dimebon 20 mg po TID, Placebo po TID - Alzheimer Disease | Phase 3 | Terminated | 86 | 2009-09-01 | 2012-10-02 |
A Safety and Efficacy Study of Dimebon in Patients With Huntington Disease Dimebon, Placebo - Huntington Disease | Phase 3 | Completed | 403 | 2009-07-01 | 2016-10-12 |
Safety and Efficacy Study Evaluating Dimebon in Patients With Mild to Moderate Alzheimer's Disease on Donepezil Dimebon, Placebo comparator - Alzheimer's Disease | Phase 3 | Completed | 1003 | 2009-03-01 | 2016-09-27 |
A Phase 3 Study To Evaluate The Safety And Tolerability Of Dimebon Patients With Mild To Moderate Alzheimer's Disease Dimebon, Placebo - Alzheimer's Disease | Phase 3 | Completed | 742 | 2009-02-01 | 2018-12-06 |
A Safety and Efficacy Study of Oral Dimebon in Patients With Mild-To-Moderate Alzheimer's Disease Dimebon, Placebo - Alzheimer's Disease | Phase 3 | Completed | 598 | 2008-05-01 | 2016-09-27 |
Conditions studied
Alzheimer Disease (7) · Dementia (3) · Breast Neoplasms (2) · Huntington Disease (2) · Memory Disorders (2) · Neurodegenerative Diseases (2) · Central Nervous System Diseases (1) · Cognitive Dysfunction (1) · Delirium (1) · Mental Disorders (1) · Neoplasm Metastasis (1) · Nervous System Diseases (1) · Prostatic Neoplasms (1)
Interventions
latrepirdine (10) · enzalutamide (2) · Administration, Oral (1) · Paclitaxel (1) · Prednisone (1) · abiraterone (1) · talazoparib (1)
Countries
United States (10) · Canada (5) · Germany (4) · United Kingdom (4) · Australia (3) · Puerto Rico (3) · Belgium (2) · France (2) · Italy (2) · Spain (2) · Sweden (2) · Brazil (1) · Chile (1) · Denmark (1) · Finland (1)
Top investigators
Lynn Seely, MD (1) · Michael Morris, M.D. (1)
Results publications
PMID 23108692, PMID 30110579, PMID 30124753, PMID 35091441, PMID 36996380, PMID 39663356, PMID 41346252
NIH funding
2016 (1), U10CA031946 (1)