11 completed, 6 unknown, 1 active not recruiting. 7 Not applicable, 4 Phase 4, 1 Early Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 5, Unknown 2 |
| Phase 4 | 4 | Completed 2, Unknown 2 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Unknown 1 |
| Phase 3 | 1 | Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multi-omics Study in Citrin Deficiency Citrin Deficiency | Active not recruiting | Johannes Haeberle | 100 | 2023-04-01 | 2026-06-02 | |
| An Open-label, Multicenter Study to Evaluate the Efficacy and Safety of Transitioning to Lemborexant in Japanese Subjects With Insomnia Lemborexant (LEM) 5 mg (Z-Drug-mono cohort), Lemborexant (LEM) 5 mg (SUV-mono cohort), Lemborexant (LEM) 5 mg (SUV-combination cohort) - Insomnia | Phase 4 | Completed | Kurume University | 97 | 2021-03-24 | 2023-03-15 |
| Combined Application of Electrical Stimulation and Volitional Contractions for Muscle Strengthening and Knee Pain Inhibition (Seated Study) Hybrid Training using Electrodes and Joint Motion Sensors, Isokinetic Training with Isokinetic Dynamometer - Knee Osteoarthritis | Not applicable | Completed | University of Kansas Medical Center | 42 | 2016-06-01 | 2018-05-18 |
| Combined Application of Electrical Stimulated Antagonist Contraction During Walking (Walking Study) Hybrid Training System (HTS), Sensory TENS - Knee Osteoarthritis | Not applicable | Completed | University of Kansas Medical Center | 28 | 2016-02-01 | 2018-06-15 |
| Efficacy of Olmesartan on Cerebral Glucose Metabolism, Vascular Inflammation and Adipose Tissue Olmesartan, Amlodipine - Efficacy of Olmesartan on Cerebral Glucose Metabolism in Essential Hypertension | Phase 4 | Unknown | Kurume University | 100 | 2015-12-01 | 2016-12-20 |
| Metabolic and Cardiovascular Effects of Dipeptidyl Peptidase-4 (DPP-4) or Sodium-glucose Co-transporter Type 2 (SGLT2) Inhibitors DPP-4 inhibiotors, SGLT2 inhibitors, Glimepiride - Effects of the DPP-4 Inhibitors or SGLT2 Inhibitors on the Protective Actions for Diabetic Complications | Phase 4 | Unknown | Kurume University | 100 | 2015-08-01 | 2015-08-19 |
| ENdothelial Healing Assessment With Novel Coronary tEchnology SYNERGY stent, BVS ABSORB scaffold - Coronary Artery Disease | Not applicable | Completed | University of Malaya | 13 | 2015-08-01 | 2017-05-04 |
| Ranibizumab Treatment for Age-Related Macular Degeneretion Intravitreal Lucentis 0.5mg - Visual Disorder Due to Age-related Macula Degeneration | Not applicable | Unknown | Kyushu University | 100 | 2013-12-01 | 2014-06-09 |
| DPP-IV Inhibitors Underlying Mechanism of Cancer in Diabetic Patients Sitagliptin, Alogliptin, Vildagliptin - Type 2 Diabetes Mellitus | Unknown | Nagaoka Red Cross Hospital | 500 | 2012-10-01 | 2012-10-19 | |
| Effects of Montelukast on Airway Regulatory T Cells in Asthma Montelukast - Asthma | Phase 2 / Phase 3 | Unknown | Kurume University | 15 | 2012-06-01 | 2013-09-27 |
| Pioglitazone Decreases Visceral Fat Metabolism Pioglitazone vs Glimepiride - To Evaluate the Effect of Pioglitazone on Glucose Metabolism of Fat Tissue by Using FDG-PET/CT Imaging | Not applicable | Unknown | Kurume University | 60 | 2012-03-01 | 2013-03-27 |
| Effects of Chronic Smoking on Circulating Endothelial and Platelet-derived Microparticle smoking cessation - Atherosclerosis | Early Phase 1 | Completed | Kurume University | 100 | 2008-11-01 | 2011-06-23 |
| Relation of Circulating Endothelium-derived Microparticle to Carotid Atherosclerosis Atherosclerosis | Completed | Kurume University | 154 | 2008-11-01 | 2015-03-31 | |
| Morning Hypertension and Preminent Therapy Study Preminent (losartan/hydrochlorothiazide combination drug) - Hypertension | Phase 4 | Completed | Kurume University | 216 | 2008-11-01 | 2011-06-23 |
| Anti-Inflammatory Effects of Pioglitazone Pioglitazone, Glimepiride - Impaired Glucose Tolerance, Type 2 Diabetes Mellitus | Not applicable | Completed | Kurume University | 70 | 2007-05-01 | 2012-09-27 |
| Retina Projection System Trials for Low Vision People Vision, Low | Completed | Osaka City University | 58 | 2005-01-01 | 2008-05-22 | |
| Detection of Plaque Inflammation by Positron Emission Tomography (PET)-Effects of Simvastatin on Plaque Inflammation simvastatin - Atherosclerosis | Not applicable | Completed | Kurume University | 43 | 2004-09-01 | 2015-06-01 |
| Cardiac Sarcoidosis and FDG-PET Sarcoidosis, Dilated Cardiomyopathy | Completed | Kurume University | 20 | 2004-03-01 | 2012-09-27 |
Atherosclerosis (4) · Diabetes Mellitus, Type 2 (2) · Osteoarthritis, Knee (2) · Adult-onset citrullinemia type 2 (1) · Asthma (1) · Cardiomyopathy, Dilated (1) · Coronary Artery Disease (1) · Glucose Intolerance (1) · Hypertension (1) · Inflammation (1) · Sarcoidosis (1) · Sleep Initiation and Maintenance Disorders (1) · Vision, Low (1)
glimepiride (2) · Amlodipine (1) · Losartan (1) · Pioglitazone (1) · Resistance Training (1) · Simvastatin (1) · Sitagliptin Phosphate (1) · Sodium-Glucose Transporter 2 Inhibitors (1) · Vildagliptin (1) · alogliptin (1) · hydrochlorothiazide, losartan drug combination (1) · lemborexant (1) · leukocyte endogenous mediator (1) · montelukast (1) · olmesartan (1)
Japan (15) · United States (3) · South Korea (1) · Taiwan (1) · United Kingdom (1)
Nobuhiro Tahara, MD, PhD (4) · Tsutomu Imaizumi, MD, PhD (3) · Hisashi Kai, MD, PhD (2) · Neil A Segal, MD (2) · Kunihiko Shiraki, MD (1) · Kyuzi Kamoi, MD (1) · Motohiro Ozone (1) · Wan Azman Wan Ahmad (1)
PMID 17418291, PMID 21999871, PMID 24030946, PMID 24229770, PMID 29766812, PMID 29852286, PMID 31407236, PMID 31592880, PMID 33210751, PMID 35337843, PMID 38460107, PMID 41103818