15 completed, 9 unknown, 2 not yet recruiting, 1 recruiting. 19 Not applicable, 4 Phase 1, 2 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 19 | Completed 10, Unknown 7, Recruiting 1, Withdrawn 1 |
| Phase 1 | 4 | Completed 2, Not yet recruiting 1, Unknown 1 |
| Phase 2 | 2 | Completed 1, Not yet recruiting 1 |
| Phase 3 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Psychological and Lifestyle Factors That Predict Adherence of Multi-domain Interventions for Promoting Brain Health Generic Lifestyle Education, ToBrainHealth Personalised Digital Intervention, ToBrainHealth Personalised Digital Intervention with Coaching - Brain Health Activities, Cognition | Not applicable | Completed | Institut Guttmann | 120 | 2026-02-15 | 2026-07-07 |
| Guttmann NeuroRecovery - Viability, Safety, and Efficacy of Intrathecal Wharton's Jelly Mesenchymal Stem Cells and Transcutaneous Spinal Cord Stimulation in Chronic Spinal Cord Injury Rehabilitation Allogeneic Wharton's jelly mesenchymal stem cells (WJ-MSCs) - Spinal Cord Injuries (SCI), Spinal Cord Injury | Phase 1 / Phase 2 | Not yet recruiting | Institut Guttmann | 10 | 2025-09-01 | 2025-05-25 |
| Acquired Brain Injury and Neurorehabilitation: the Influence of Psychological Characteristics Neurorehabilitation program - Brain Injury, Stroke Patients | Not yet recruiting | Institut Guttmann | 200 | 2024-11-01 | 2024-10-28 | |
| Machine-Learning Based EEG Biomarkers for Personalized Interventions transcranial Direct Current Stimulation, Electroencephalography - Neuropathic Pain, Spinal Cord Injuries | Unknown | Institut Guttmann | 58 | 2023-10-05 | 2024-07-31 | |
| Home-based Stimulation to Promote Resilience Transcranial Direct Current Stimulation (tDCS) - Stress | Not applicable | Unknown | Institut Guttmann | 40 | 2023-09-01 | 2023-09-22 |
| Exoskeleton Gait Training in Guillain-Barré Syndrome: Safety, Feasibility, Usability, and Longitudinal Outcomes Exoskeleton Wandercraft Atalante X, usability and gait rehabilitation - Guillain Barré Syndrome | Not applicable | Completed | Institut Guttmann | 11 | 2023-08-07 | 2026-05-08 |
| Home-based Non-invasive Brain Stimulation for Treatment-resistant Depression Feasibility, Efficacy and Biomarker of Treatment Response Non-invasive transcranial direct current stimulation (tDCS) - Major Depressive Disorder | Not applicable | Completed | Institut Guttmann | 40 | 2023-06-15 | 2026-07-02 |
| Clinical Investigation on Feasibility and Usability of the ABLE Exoskeleton Device for Individuals With Spinal Cord Injury to Perform Skills for Home and Community Environments ABLE Exoskeleton - Spinal Cord Injuries | Not applicable | Completed | ABLE Human Motion S.L. | 10 | 2022-11-25 | 2023-10-19 |
| Reliability of a Gait Analysis System SILEMA - Gait Analysis | Completed | Centro Integral de Neurologia y Especialidades Afines, Argentina | 18 | 2022-10-20 | 2022-11-08 | |
| Promote Brain Resilience for the Coronavirus (COVID-19) Pandemic Transcranial Alternate Current Stimulation, Sham stimulation - Transcranial Direct Current Stimulation, Mental Health Issue | Not applicable | Unknown | Institut Guttmann | 40 | 2022-09-01 | 2023-06-23 |
| Cell Therapy for Chronic Traumatic Cervical Incomplete Spinal Cord Injury WJ-MSC (XCEL-UMC-BETA), Placebo - Spinal Cord Injury Cervical | Phase 1 / Phase 2 | Completed | Banc de Sang i Teixits | 18 | 2021-10-13 | 2024-01-24 |
| Prehabilitation, Rehabilitation and Comprehensive Approach to the Sequelae of Brain Tumors Non-invasive neuromodulation (TMS and/or tDCS) - Brain Tumor | Phase 1 | Unknown | Institut Guttmann | 20 | 2021-06-21 | 2023-05-06 |
| Development of a Novel Strategy to Analyze the Effect on Gait Using Transcutaneous Spinal Current Stimulation in Incomplete Spinal Cord Injured Patients transcutaneous spinal cord stimulation - Spinal Cord Injuries, Non Invasive Spinal Stimulation | Not applicable | Recruiting | Institut Guttmann | 10 | 2021-01-01 | 2025-12-17 |
| Clinical Investigation on Safety, Feasibility and Usability of the ABLE Exoskeleton Device With Spinal Cord Injured Patients in a Hospital Setting ABLE Exoskeleton - Spinal Cord Injuries | Not applicable | Completed | ABLE Human Motion S.L. | 24 | 2020-11-03 | 2022-01-14 |
| Exercise the Mind and Brain. A Multimodal Intervention in Stroke Multicomponent Physical Activity Program, Mindfulness-Based Stress Reduction Program, Computerized Cognitive Training - Stroke | Not applicable | Completed | University of Barcelona | 141 | 2020-10-28 | 2022-03-02 |
| Regain of Arm and Hand Movements in Cervical Spinal Stimulation cervical transcutaneous spinal cord stimulation - Spinal Cord Injuries | Not applicable | Completed | Institut Guttmann | 40 | 2020-09-01 | 2025-08-24 |
| Community-based Occupational Therapy Intervention on Mental Health for People With Acquired Brain Injury Community-based Occupational Therapy, Standard community-based intervention - Acquired Brain Injury, Mental Health Issue | Not applicable | Unknown | Institut Guttmann | 134 | 2020-09-01 | 2022-07-19 |
| Efficacy and Safety of rTMS Plus Rehabilitation for the Improvement of the Upper Extremity in Stroke (ERES) Real rTMS (Magstim), Sham rTMS - Stroke, Arm Paralysis | Not applicable | Unknown | Institut Guttmann | 24 | 2019-10-15 | 2019-10-11 |
| Clinical Trial of The Boosting Effect of Transcranial Random Noise Stimulation (tRNS) in Cognitive Rehabilitation of Patients With Traumatic Brain Injury Real tRNS, Sham tRNS - Traumatic Brain Injury, Cognitive Impairment | Not applicable | Unknown | Institut Guttmann | 30 | 2019-02-25 | 2019-02-26 |
| Rehabilitation of Social Cognition in Subjects With Traumatic Brain Injury GNPT+ Social Cognition, GNPT - Cognition Disorders | Not applicable | Unknown | Institut Guttmann | 45 | 2018-01-02 | 2020-02-13 |
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Spinal Cord Injuries (11) · Brain Injuries, Traumatic (3) · Brain Injuries (2) · Cognitive Dysfunction (2) · Neuralgia (2) · Paraplegia (2) · Stroke (2) · Amyotrophic Lateral Sclerosis (1) · Brain Neoplasms (1) · COVID-19 (1) · Cognition Disorders (1) · Confusion (1) · Depressive Disorder, Major (1) · Gait Disorders, Neurologic (1) · Guillain-Barre Syndrome (1)
Transcranial Direct Current Stimulation (2) · Cognitive Training (1) · Electroencephalography (1) · Exercise (1) · Neurological Rehabilitation (1) · Rehabilitation (1)
Spain (24) · Germany (2) · Argentina (1) · Switzerland (1)
Angel Gil-Agudo, PhD, MD (1) · Bernardo Centeno (1) · Dolors Soler, PhD (1) · Eloy E Opisso (1) · Hatice Kumru, MD PhD (1) · Maria Mataro Serrat, Ph.D. (1) · Maria Mataro, PhD (1) · Martin Schubert, MD (1) · Narda Murillo, PhD (1) · Ulrich Mehnert, MD (1)
PMID 11909906, PMID 12105363, PMID 18940690, PMID 19678808, PMID 19798637, PMID 19802336, PMID 20402755, PMID 22177936, PMID 22238412, PMID 22518248, PMID 22588639, PMID 23326685, PMID 25034472, PMID 25829989, PMID 25877360, PMID 31481889, PMID 33192485, PMID 35196474, PMID 36206208, PMID 36248000, PMID 37849833, PMID 39391753, PMID 40845631, PMID 9474057
2025 (1)