4 completed, 2 terminated, 1 unknown. 7 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 4, Terminated 2, Unknown 1 |
| Phase 3 | 2 | Completed 1, Terminated 1 |
| Phase 1 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Assess the Efficacy and Safety of Allogeneic Osteoblastic Cells (ALLOB®) Single Implantation in Tibial Fracture ALLOB, placebo - Tibial Fracture | Phase 2 | Unknown | Bone Therapeutics S.A | 178 | 2021-01-08 | 2021-06-07 |
| A Study on Visco-antalgic Intra-articular Administration in Symptomatic Knee Osteoarthritis JTA-004 intra-articular injection, Reference product intra-articular injection - Knee Osteoarthritis | Phase 2 / Phase 3 | Completed | Bone Therapeutics S.A | 173 | 2016-02-01 | 2021-12-06 |
| Phase 2a Study on Allogeneic Osteoblastic Cells Implantation in Lumbar Spinal Fusion ALLOB® cells with ceramic scaffold - Degenerative Disc Disease | Phase 2 | Completed | Bone Therapeutics S.A | 38 | 2014-10-01 | 2021-01-29 |
| Study on Allogeneic Osteoblastic Cells Implantation in Rescue Interbody Fusion ALLOB® - Failed Lumbar Fusion | Phase 2 | Terminated | Bone Therapeutics S.A | 6 | 2014-09-01 | 2020-06-11 |
| Phase 1/2a Study on Allogeneic Osteoblastic Cells Implantation in Delayed-Union Fractures ALLOB® implantation - Long Bone Delayed-Union Fracture | Phase 1 / Phase 2 | Completed | Bone Therapeutics S.A | 25 | 2014-02-01 | 2021-11-10 |
| Study on Autologous Osteoblastic Cells Implantation in Hypotrophic Non-Union Fractures PREOB® Implantation, Bone Autograft - Long Bone Non-Union | Phase 2 / Phase 3 | Terminated | Bone Therapeutics S.A | 5 | 2012-06-01 | 2020-06-11 |
| Autologous Osteoblastic Cells Implantation to Early Stage Osteonecrosis of the Femoral Head Core decompression/PREOB® implantation, Core decompression/BMC implantation - Avascular Necrosis of Femur Head | Phase 2 | Completed | Erasme University Hospital | 82 | 2003-10-01 | 2016-09-07 |
Musculoskeletal Diseases (3) · Fractures, Bone (2) · Arthritis (1) · Femur Head Necrosis (1) · Intervertebral Disc Degeneration (1) · Osteoarthritis (1) · Osteoarthritis, Knee (1) · Osteonecrosis (1) · Pseudarthrosis (1) · Tibial Fractures (1)
Belgium (5) · France (2) · Czechia (1) · Germany (1) · Hungary (1) · Netherlands (1) · Poland (1) · Spain (1)