31 completed, 3 unknown, 2 not yet recruiting, 2 recruiting. 40 Phase 3, 12 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 40 | Completed 31, Unknown 3, Not yet recruiting 2, Recruiting 2, Terminated 1, Withdrawn 1 |
| Phase 2 | 12 | Completed 8, Not yet recruiting 2, Recruiting 1, Unknown 1 |
Follow Water: new trials by email Literature Review of Water trials Research Report on Water
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Injection of IP-001 Into Thermally Ablated Hepatic Tumors in Patients With Colorectal Liver Metastases 1.0% IP-001 for Injection, a 10 mg/mL solution of IP-001 in water, 1.0% IP-001 for Injection, a 1 mg/mL solution of IP-001 in water., Microwave (thermal) tumor ablation - Colorectal Cancer (CRC), Colon Cancer Liver Metastases | Phase 2 / Phase 3 | Not yet recruiting | Immunophotonics, Inc. | 717 | 2026-05-01 | 2026-01-07 |
| Postpartum 8-aminoquinoline Breast Milk Study Daily primaquine (0.5 mg/kg per day) for 14 days given with food food and water, Daily primaquine 1 mg/kg per day for 7 days given with food and water, Single-dose tafenoquine given with food and water to prevent gastrointestinal discomfort - Drug Pharmacokinetics in Healthy Volunteers | Phase 2 / Phase 3 | Not yet recruiting | Curtin University | 60 | 2026-04-01 | 2026-03-18 |
| Efficacy Testing of a Multi-Level Family Planning Intervention Family Planning Intervention, Water, Sanitation, and Hygiene (WASH) Intervention - Unintended Pregnancy, Family Planning | Phase 2 / Phase 3 | Recruiting | Boston College | 1464 | 2025-06-12 | 2026-03-23 |
| Biperiden Trial for Epilepsy Prevention Biperiden, Placebo - Brain Injury Traumatic Moderate, Brain Injury Traumatic Severe | Phase 3 | Recruiting | Hospital Sirio-Libanes | 312 | 2023-01-10 | 2024-03-26 |
| High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda Ascorbic Acid 500Mg/Ml Inj, Dextrose in Water - Sepsis | Phase 3 | Withdrawn | Virginia Commonwealth University | 2022-10-01 | 2022-10-18 | |
| Suaahara Impact Evaluation: End-line Survey Health and family planning, Nutrition, Agriculture and homestead food production - Nutritional Stunting, Feeding Behavior | Phase 3 | Completed | University of South Carolina | 2480 | 2022-06-17 | 2023-01-06 |
| Efficacy and Safety of Ethanol Inhalation on COVID-19 Treatment (a Clinical Trial Study) Ethanol, Water Distilled - Clinical Infection, Outcome | Phase 3 | Completed | Ali Amoushahi | 150 | 2021-09-02 | 2022-04-25 |
| Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving Gemcitabine and Carboplatin for Metastatic Triple-Negative Breast Cancer (TNBC) Trilaciclib, Placebo, Gemcitabine - TNBC - Triple-Negative Breast Cancer, Breast Cancer | Phase 3 | Completed | G1 Therapeutics, Inc. | 194 | 2021-05-14 | 2024-08-01 |
| Non-Invasive Vagal Nerve Stimulation in Opioid Use Disorders Non invasive VN stimulation (nVNS), Oxygen (15-O) Water, Sham Stimulation - Substance-Related Disorders, Substance Use Disorders | Phase 3 | Completed | Emory University | 20 | 2020-11-13 | 2023-09-13 |
| Efficacy of Zinc L-Carnosine Mouth Rinse Zinc L-Carnosine, Chlorhexidine, Water - Periodontal Index, Pain | Phase 3 | Unknown | University of Milan | 75 | 2020-06-01 | 2020-06-18 |
| Surgical Idiopathic Intracranial Hypertension Treatment Trial Acetazolamide, Optic Nerve Sheath Fenestration, Ventriculoperitoneal CSF Shunting - Idiopathic Intracranial Hypertension | Phase 3 | Terminated | Jaeb Center for Health Research | 7 | 2019-02-06 | 2022-06-16 |
| Evaluation of Oral Simethicone With Low Volume Polyethylene Glycol Bowel Preparation During Colonoscopy Simethicone Solution, Water - Colonoscopy | Phase 3 | Completed | University of Nevada, Reno | 250 | 2018-01-09 | 2018-12-12 |
| Benefit of Clarithromycin in Patients With Severe Infections Through Modulation of the Immune System Clarithromycin, Water for injection - Sepsis, Pneumonia | Phase 3 | Completed | Hellenic Institute for the Study of Sepsis | 110 | 2017-12-15 | 2020-12-22 |
| Efficacy and Safety of Cytoflavin® Used in Elderly Patients for the Prevention of Cognitive Decline After Major Surgery Cytoflavin® solution, Cytoflavin® enteric-coated tablet, Placebo solution - Cognitive Dysfunction | Phase 3 | Completed | POLYSAN Scientific & Technological Pharmaceutical Company | 200 | 2017-06-02 | 2023-01-31 |
| The Fluid Therapy Strategy of the Non-dehydrated Patients With Acute Ischemic Stroke. water - Stroke, Dehydration | Phase 2 / Phase 3 | Unknown | Chang Gung Memorial Hospital | 250 | 2016-01-01 | 2017-06-23 |
| Stopping Cavities Study: Diammine Silver Fluoride 38% diammine silver fluoride, Water - Dental Caries | Phase 3 | Completed | Advantage Dental Services, LLC | 66 | 2016-01-01 | 2020-01-23 |
| Sanitation, Water, and Instruction in Face-washing for Trachoma I/II Water, sanitation, and hygiene (WASH) intervention, Standard of care WASH intervention, Azithromycin - Trachoma | Phase 3 | Completed | University of California, San Francisco | 47605 | 2015-12-05 | 2026-06-04 |
| Small Volume Simethicone Before Gastroscopy: Any Benefit? Simethicone, Water - Lesion of Stomach | Phase 2 / Phase 3 | Completed | Changi General Hospital | 54 | 2015-08-01 | 2016-03-15 |
| Pre-procedural Mouthwash in Reducing Bacteria in Dental Aerosols Dental prophylaxis, Mouthwash CPC+Zn+F, Mouthwash CHX - Chronic Periodontitis | Phase 3 | Completed | University of Guarulhos | 60 | 2015-02-01 | 2020-06-04 |
| A Trial Of Intravenous N-Acetylcysteine In The Management Of Antituberculous Drug-Induced Hepatitis IV N-acetylcysteine (NAC), Water - Drug-Induced Liver Injury | Phase 2 / Phase 3 | Completed | University of Cape Town | 102 | 2014-05-01 | 2019-02-19 |
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Pain (4) · Breast Neoplasms (3) · Dental Caries (3) · Neoplasm Metastasis (2) · Neoplasms (2) · Sepsis (2) · Agammaglobulinemia (1) · Agnosia (1) · Brain Injuries (1) · Breast Feeding (1) · COVID-19 (1) · Cancer Pain (1) · Chemical and Drug Induced Liver Injury (1) · Chronic Periodontitis (1) · Cognitive Dysfunction (1)
The University of Hong Kong (2) · Tranzyme, Inc. (2) · Advantage Dental Services, LLC (1) · Ali Amoushahi (1) · Boston College (1) · British Columbia Cancer Agency (1) · Carmel Medical Center (1) · Centre Hospitalier Universitaire, Amiens (1) · Chang Gung Memorial Hospital (1) · Changi General Hospital (1) · Colgate Palmolive (1) · Curtin University (1) · Emory University (1) · Federal University of São Paulo (1) · G1 Therapeutics, Inc. (1)
United States (15) · Canada (6) · France (4) · Italy (4) · Bulgaria (3) · China (3) · Poland (3) · Romania (3) · Russia (3) · United Kingdom (3) · Czechia (2) · Hungary (2) · Ukraine (2) · Australia (1) · Belgium (1)
Edward CM Lo, BDS, PhD (2) · Anna Taddio, PhD (1) · Anne M. Lynn, MD (1) · Apostolos Armaganidis, MD, PhD (1) · Aurimery G Chermont (1) · Brioni Moore, PhD (1) · Chiara Occhipinti, Professor (1) · Dennis A Hopkinson, MD (1) · Diane M Beatty, PhD (1) · Dionna M Wittberg, MPH (1) · Edward A Frongillo, PhD (1) · Elham Moazam, Researcher (1) · Eliana Garzon, MD, PhD (1) · Elizabeth A Mittendorf, MD,FACS (1)
PMID 23739196, PMID 10933646, PMID 15316186, PMID 17456651, PMID 18444850, PMID 19948613, PMID 20042524, PMID 20354090, PMID 20610825, PMID 21199130, PMID 22564837, PMID 23055587, PMID 24024983, PMID 24292991, PMID 24685786, PMID 24768671, PMID 24807329, PMID 24992844, PMID 26215946, PMID 26338107, PMID 26478974, PMID 27044546, PMID 27956393, PMID 28455250, PMID 30938645, PMID 31036542, PMID 33619183, PMID 34919861, PMID 35717241, PMID 36041704, PMID 36084082, PMID 36135712, PMID 38134305, PMID 38342986, PMID 38991011, PMID 40548916, PMID 41314021, PMID 41548574, PMID 7499664
2025 (1), P01DK068055 (1), R01HD113806 (1), U01DK072146 (1), U10EY023939 (1), U10EY025990 (1), UG3DA048502 (1)