20 completed, 9 unknown, 4 recruiting, 4 terminated. 41 Phase 3, 12 Phase 2.
Follow Vitamin C: new trials by email Literature Review of Vitamin C trials Research Report on Vitamin C
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Renoprotective Role of Vitamin C and Coenzyme Q10 in Nephrotoxicity Vitamin C, Coenzyme Q 10 - Nephrotoxicity | Phase 2 / Phase 3 | Not yet recruiting | Ain Shams University | 75 | 2026-04-20 | 2026-03-17 |
| Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation Metformin, Rapamycin, Naltrexone - Longevity, GLP-1 | Phase 2 / Phase 3 | Recruiting | AgelessRx | 150 | 2024-12-17 | 2025-07-30 |
| Combination of IV Ascorbic Acid and Adebrelimab in Metastatic Colorectal Cancer Ascorbic acid, FOLFOX Protocol, Adebrelimab - Colorectal Cancer, Vitamin C | Phase 3 | Recruiting | Fudan University | 400 | 2024-12-01 | 2024-10-24 |
| Vitamin C to Chemotherapy Related Anemia in Pancreatic Cancer Ascorbate, Nab paclitaxel, Gemcitabine - Metastatic Pancreatic Adenocarcinoma | Phase 3 | Unknown | Fudan University | 100 | 2023-08-20 | 2025-08-07 |
| Immunonutrition for Diabetic Foot Ulcers Lovaza, L-Arginine Powder, Vitamin C - Diabetes Mellitus, Diabetic Peripheral Neuropathy | Phase 2 / Phase 3 | Terminated | Prisma Health-Midlands | 1 | 2023-02-08 | 2024-12-27 |
| Efficacy of Megadose Vitamin C in Severe and Critical Ill COVID-19 Patients. Vitamin C, Placebo - Vitamin C, COVID-19 Pneumonia | Phase 2 / Phase 3 | Unknown | Zhujiang Hospital | 608 | 2023-01-13 | 2023-01-23 |
| The Effect of Vitamin C and E Therapy on Restless Leg Syndrome in Patients With End Stage Renal Disease on Haemodialysis Ascorbic acid, Tocopherol, Placebo capsule - Restless Legs Syndrome, End Stage Renal Disease | Phase 3 | Unknown | King Abdulaziz University | 160 | 2022-11-01 | 2022-08-24 |
| Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Vitamin C, Placebo - Sepsis, Septic Shock | Phase 3 | Terminated | Hospital Sirio-Libanes | 71 | 2021-08-01 | 2024-01-30 |
| Clinical Trial With N-acetylcysteine and Bromhexine for COVID-19 Vitamin C, N-acetylcysteine (NAC), NAC + Bromhexine (BMX) - COVID-19 | Phase 3 | Unknown | Universidade Federal do Ceara | 219 | 2021-07-15 | 2021-06-30 |
| Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments Vitamin C, Normal saline - Sepsis, Septic Shock | Phase 3 | Completed | Universitaire Ziekenhuizen KU Leuven | 301 | 2021-06-01 | 2024-01-25 |
| Lessening Organ Dysfunction With VITamin C - COVID-19 Vitamin C, Control - Vitamin C, COVID-19 | Phase 3 | Completed | Université de Sherbrooke | 392 | 2020-08-14 | 2023-04-21 |
| VItamin C in Thermal injuRY: The VICToRY Trial Ascorbic Acid, placebo - Shock, Thermal Burn | Phase 3 | Suspended | Clinical Evaluation Research Unit at Kingston General Hospital | 666 | 2020-07-24 | 2026-04-06 |
| A Preventive Treatment for Migrant Workers at High-risk of COVID-19 Hydroxychloroquine Sulfate Tablets, Ivermectin 3mg Tab, Zinc - Covid-19 | Phase 3 | Completed | National University Hospital, Singapore | 4257 | 2020-05-13 | 2020-10-19 |
| Trial of IV vs Oral Iron Treatment of Iron Deficiency Anemia in the Post-Operative Bariatric Surgical Patient Ferumoxytol, Saline, Ferrous sulfate tablets - Iron Deficiency Anemia | Phase 3 | Recruiting | Auerbach Hematology Oncology Associates P C | 104 | 2020-02-27 | 2025-10-03 |
| Effect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic Shock Vitamin C, Normal saline - Septic Shock | Phase 3 | Terminated | New York Presbyterian Brooklyn Methodist Hospital | 3 | 2019-10-15 | 2020-02-10 |
| Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis Vitamin C, Hydrocortisone, Complex B - Sepsis, Septic Shock | Phase 3 | Completed | IMSS Hospital General de Zona 11, Piedras Negras | 19 | 2019-09-01 | 2020-10-19 |
| Intravenous Ascorbic Acid Administration in Hysterectomy vitamin C - Abdominal Hysterectomy | Phase 3 | Completed | Shahid Beheshti University | 80 | 2019-08-23 | 2020-05-04 |
| Vitamin C to Reduce Vasopressor Dose in Septic Shock Vitamin C, Placebos - Septic Shock, Sepsis | Phase 3 | Withdrawn | Hospital Español de Mexico | 2019-03-01 | 2024-01-18 | |
| Lessening Organ Dysfunction With VITamin C Vitamin C, Control - Sepsis, Vitamin C | Phase 3 | Completed | Université de Sherbrooke | 872 | 2018-11-08 | 2022-04-04 |
| Vitamin C, Thiamine, and Steroids in Sepsis Vitamin C, Thiamine, Hydrocortisone - Sepsis | Phase 3 | Completed | Emory University | 501 | 2018-08-22 | 2021-04-13 |
Showing 20 of 41. Sign in to see all of them.
Sepsis (7) · COVID-19 (6) · Shock, Septic (6) · Atrial Fibrillation (3) · Colorectal Neoplasms (3) · Anemia (2) · Attention Deficit Disorder with Hyperactivity (2) · Coronavirus Infections (2) · Diabetes Mellitus (2) · Impulsive Behavior (2) · Kidney Failure, Chronic (2) · Restless Legs Syndrome (2) · Anemia, Iron-Deficiency (1) · Arrhythmias, Cardiac (1) · Arterial Occlusive Diseases (1)
Ain Shams University (3) · Fudan University (2) · Sun Yat-sen University (2) · Université de Sherbrooke (2) · Aga Khan University (1) · AgelessRx (1) · Attikon Hospital (1) · Auerbach Hematology Oncology Associates P C (1) · Centre Hospitalier Universitaire, Amiens (1) · Clinical Evaluation Research Unit at Kingston General Hospital (1) · Emory University (1) · Hospital Español de Mexico (1) · Hospital Sirio-Libanes (1) · IMSS Hospital General de Zona 11, Piedras Negras (1) · Kieran Cooley (1)
United States (10) · Canada (7) · China (5) · Belgium (3) · Egypt (3) · Mexico (3) · Brazil (2) · France (2) · Germany (2) · India (2) · Iran (2) · Italy (2) · Thailand (2) · United Kingdom (2) · Australia (1)
Rui-hua Xu, MD.,PhD. (2) · Umesh Jain, MD (2) · Colin McArthur, Dr (1) · Daren K Heyland, MD (1) · Derek Angus, Prof (1) · Didier Desruelles, MD (1) · Gianfranco Pagano, MD (1) · Gisele Queiroz, MD (1) · Guopei Luo, MD (1) · Guoxiang Cai, Doctor (1) · Hamideh Akbari, MD (1) · Heather Boon, PhD (1)
PMID 37877585, PMID 19237716, PMID 19446899, PMID 25801556, PMID 26201606, PMID 29438178, PMID 30953543, PMID 31096937, PMID 31801567, PMID 31915072, PMID 31987106, PMID 32007132, PMID 32102933, PMID 32267771, PMID 32317004, PMID 32876697, PMID 33394942, PMID 33509275, PMID 33620405, PMID 33631065, PMID 34020705, PMID 34251506, PMID 34351721, PMID 34351722, PMID 34473343, PMID 34606578, PMID 34739527, PMID 34982738, PMID 35315874, PMID 35623878, PMID 35704292, PMID 36853612, PMID 36942550, PMID 36967714, PMID 37039790, PMID 37489818, PMID 37888913, PMID 37916745, PMID 39075587, PMID 39774855, PMID 40261382, PMID 40269974, PMID 40360262, PMID 40845939, PMID 40927646, PMID 42267875, PMID 42361956, PMID 42823695
2015 (2), 2005 (1), 2023 (1)