14 completed, 2 active not recruiting, 2 recruiting, 2 unknown. 15 Not applicable, 2 Phase 2, 1 Phase 1, 1 Phase 3, 1 Phase 4.
Follow Very Low Calorie Diet: new trials by email Literature Review of Very Low Calorie Diet trials Research Report on Very Low Calorie Diet
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Naltrexone/Bupropion With or Without Very Low Calorie Ketogenic Diet for Weight Regain After Bariatric Surgery Very Low Calorie Diet - Weight Regain Post Bariatric Surgery, Obesity (Disorder) | Not applicable | Recruiting | Universitaire Ziekenhuizen KU Leuven | 62 | 2025-01-20 | 2025-03-21 |
| The Medically Reproducing Bariatric Surgery (MRB) II Study Very Low Calorie Diet - Type 2 Diabetes, Obesity | Phase 2 / Phase 3 | Active not recruiting | Durham VA Medical Center | 50 | 2024-06-24 | 2025-02-07 |
| Acceptability and Feasibility of a Preoperative Very Low Calorie Diet Intervention on Surgical Weight Loss Outcomes (SAFETY) Very Low Calorie Diet - Obesity | Not applicable | Unknown | Hartford Hospital | 30 | 2024-03-05 | 2024-02-28 |
| The Effect of an Anti-obesity Drug, Semaglutide, as Treatment in New-onset Idiopathic Intracranial Hypertension (IIH) Compared to Standard Weight Management (Dietician) With Regards to Change in Weight and Intracranial Pressure Semaglutide, Very Low Calorie Diet, Dietician counselling - Idiopathic Intracranial Hypertension, Intracranial Pressure | Phase 4 | Completed | Rigmor Højland Jensen | 38 | 2022-09-02 | 2026-02-27 |
| VLCD & Adjuvant Exercise Effect in Overweight Diabetic Men Very Low Calorie Diet, High Intensity Interval Training - Diabetes Mellitus Type 2 in Obese | Not applicable | Completed | University of Nottingham | 21 | 2020-01-01 | 2023-02-16 |
| Oxidative Stress and L-CBMN Cytome Assay in Obese After 3 Weeks VLCD Very low calorie diet - Obesity, Weight Loss | Not applicable | Completed | Special Hospital for Extended Treatment of Duga Resa | 26 | 2019-06-14 | 2021-09-24 |
| Changes in Anthropometric, Biochemical and DNA Damage Parameters After 3-weeks VLCD in Severely Obese Patients Very low calorie diet - Obesity, Weight Loss | Not applicable | Completed | Special Hospital for Extended Treatment of Duga Resa | 22 | 2019-06-14 | 2021-08-16 |
| Omega-3 vs Very Low Calorie Diet for Liver Size Reduction Omega-3, Very Low Calorie Diet - Obesity, Morbid, Obesity | Not applicable | Unknown | McMaster University | 60 | 2019-01-01 | 2018-03-22 |
| Utilization of Very Low Calorie Diet in Obese General Surgery Patients Very low calorie diet - Morbid Obesity | Not applicable | Completed | Christiana Care Health Services | 58 | 2018-09-24 | 2021-01-28 |
| Preservation of Fat Free Mass During Weight Loss Whey protein supplementation, walking program, Very Low Calorie Diet - Muscle Loss | Not applicable | Completed | University of Aarhus | 29 | 2016-01-08 | 2017-04-07 |
| Impact of Body Weight and Weight Loss on Drug Bioavailability, Cardiovascular Risk Factors and Metabolic Biomarkers Gastric bypass, Very low calorie diet - Obesity | Not applicable | Active not recruiting | The Hospital of Vestfold | 100 | 2015-03-18 | 2024-10-02 |
| Effect of a Very Low Calorie and Low Calorie Diet on Moderate to Severe Obstructive Sleep Apnea in Obese Adults Low Calorie Diet, Very Low Calorie Diet, Standard Care - Obstructive Sleep Apnea | Not applicable | Completed | University of Kansas Medical Center | 37 | 2014-09-01 | 2018-04-05 |
| The Effect of a Short-term Very Low Calorie Diet on Heart Rate Variability in Obese Individuals Very low calorie diet, Standard weight loss diet - Obesity | Not applicable | Completed | King's College London | 31 | 2014-05-01 | 2020-11-06 |
| Gut Hormones and Roux en Y Gastric Bypass Roux en Y Gastric Bypass Surgery, Gut hormone infusion, Placebo infusion - Obesity, Type 2 Diabetes | Not applicable | Recruiting | Imperial College London | 190 | 2013-10-01 | 2021-04-20 |
| Diet Induced Weight Loss to Reduce Inflammation in Obese Women Diet regimen to induce weight loss - Obesity | Not applicable | Completed | Rockefeller University | 22 | 2012-09-01 | 2014-11-05 |
| Very Low Calorie Diet for Diabetic Kidney Disease very low calorie diet - Diabetic Kidney Disease | Not applicable | Completed | Indiana University | 10 | 2012-03-01 | 2015-08-28 |
| RYGB and the Gastric Adipose Axis human ghrelin, very low calorie diet, Hyperinsulinemic/Euglycemic Clamp - Obesity | Phase 1 | Completed | Vanderbilt University | 49 | 2012-01-01 | 2018-05-21 |
| Caloric Restriction and Insulin Secretion Very Low Calorie Diet - Morbid Obesity, Type 2 Diabetes Mellitus | Not applicable | Completed | University of Rome Tor Vergata | 14 | 2010-01-01 | 2011-10-06 |
| Changes in Insulin Sensitivity After Weight Loss Gastric bypass, Gastric banding, Sleeve gastrectomy - Obesity, Type 2 Diabetes Mellitus | Completed | Columbia University | 119 | 2005-03-01 | 2019-09-19 | |
| Effects of Leptin Treatment on Weight Loss Leptin, Very Low Calorie Diet - Obesity | Phase 2 | Completed | Rockefeller University | 40 | 2001-03-01 | 2010-10-19 |
Obesity (15) · Diabetes Mellitus, Type 2 (4) · Weight Loss (4) · Obesity, Morbid (3) · Diabetes Mellitus (1) · Diabetic Nephropathies (1) · Insulin Resistance (1) · Motor Activity (1) · Muscular Atrophy (1) · Non-alcoholic Fatty Liver Disease (1) · Overweight (1) · Papilledema (1) · Platelet Glycoprotein IV Deficiency (1) · Pseudotumor Cerebri (1) · Sleep Apnea, Obstructive (1)
Rockefeller University (2) · Special Hospital for Extended Treatment of Duga Resa (2) · Christiana Care Health Services (1) · Columbia University (1) · Durham VA Medical Center (1) · Hartford Hospital (1) · Imperial College London (1) · Indiana University (1) · King's College London (1) · McMaster University (1) · Rigmor Højland Jensen (1) · The Hospital of Vestfold (1) · Universitaire Ziekenhuizen KU Leuven (1) · University of Aarhus (1) · University of Kansas Medical Center (1)
United States (9) · United Kingdom (3) · Croatia (2) · Belgium (1) · Denmark (1) · Italy (1) · Norway (1)
Mirta Milic, PhD (2) · Ana-Marija Domijan, Prof. (1) · Caitlin A Halbert, DO, MS (1) · Dennis Hong, MD (1) · Dragan Bozcevic, Doctor (1) · Iskandar Idris, BMBS FRCP DM (1) · Jeannine Goetz, PhD (1) · Jeffrey Friedman, MD, PHD (1) · Judith Korner, MD,PhD (1) · Mette Hansen, Lector (1) · Moahad Dar, MD (1) · Naji Abumrad, MD (1) · Peter R. Holt, MD (1) · Rigmor H Jensen, Professor (1)
PMID 22318758, PMID 23610060, PMID 23929927, PMID 29844102, PMID 30176893, PMID 31177183, PMID 34460933, PMID 35623833, PMID 35648149, PMID 35724307, PMID 36037309, PMID 36345253, PMID 36811311, PMID 38959017
R01DK091748 (1), R21DK081050 (1)