13 completed, 3 unknown, 1 withdrawn. 8 Phase 3, 6 Not applicable, 2 Phase 4, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 6, Unknown 1, Withdrawn 1 |
| Not applicable | 6 | Completed 5, Unknown 1 |
| Phase 4 | 2 | Completed 2 |
| Early Phase 1 | 1 | Unknown 1 |
Follow Tobramycin, Dexamethasone Drug Combination: new trials by email Literature Review of Tobramycin, Dexamethasone Drug Combination trials Research Report on Tobramycin, Dexamethasone Drug Combination
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tobradex as Intracanal Medicament Calcium Hydroxide (Ca(OH)2), Tobramycin + Dexamethasone - Symptomatic Irreversible Pulpitis, Postoperative Endodontic Pain Following Emergency Root Canal Treatment | Not applicable | Completed | Umm Al-Qura University | 43 | 2023-07-01 | 2026-01-13 |
| To Study Efficacy and Safety of Tobradex Eye Drop Suspension vs Tobramycin/Dexamethasone Ophthalmic Suspension Tobramycin/dexamethasone opthalmic solution, Tobradex Opthalmic Solution - Blepharo Conjunctivitis | Early Phase 1 | Unknown | Sutphin Drugs | 5000 | 2019-06-15 | 2019-06-05 |
| Levo-Dexa vs. Tobra+Dexa for Prevention and Treatment of Inflammation and Prevention of Infection in Cataract Surgery Levofloxacin + dexamethasone followed by dexamethasone, Tobramycin + Dexamethasone - Cataract | Phase 3 | Completed | NTC srl | 808 | 2018-09-03 | 2020-08-18 |
| Effects of Holy-Comod and Tears Naturale Forte in Patients After Phaco+IOL Hylo-Comod eye drop, Tears Naturale Forte eye drop - Age-related Cataract | Not applicable | Unknown | Sun Yat-sen University | 80 | 2016-06-01 | 2016-11-28 |
| Early Changes Among FLEx, LASIK and FS-LASIK lenticule extraction, laser in situ keratomileusis, FS assisted laser in situ keratomileusis - Myopia, Astigmatism | Not applicable | Completed | Sun Yat-sen University | 75 | 2015-09-01 | 2016-06-14 |
| Early Changes Between Lenticule Extraction and Small-Incision Lenticule Extraction lenticule extraction, small-incision lenticule extraction - Myopia, Astigmatism | Not applicable | Completed | Sun Yat-sen University | 41 | 2014-04-01 | 2016-11-28 |
| Effectiveness Comparison Between the Drugs TOBRACORT® and TOBRADEX® in Reducing the Signs and Symptoms of Acute Bacterial Conjunctivitis Tobracort, Tobradex - Acute Bacterial Conjunctivitis | Phase 3 | Unknown | Azidus Brasil | 70 | 2011-02-01 | 2010-10-25 |
| Chalazion Conservative Treatment Trial Hot Compress plus Tobramycin Drops and Ointment, Hot compress plus Tobramycin/Dexamethasone Drops and Ointment, Hot Compresses - Chalazion Unspecified Eye, Unspecified Eyelid, Chalazion Left Eye, Unspecified Eyelid | Not applicable | Completed | McMaster University | 150 | 2010-11-01 | 2018-06-12 |
| A Study to Evaluate the Clinical Efficacy and Safety of Tobradex® ST Compared to Azasite® in the Treatment of Subjects With Moderate to Severe Chronic Blepharitis Tobradex ST, Azasite - Blepharitis | Phase 3 | Completed | Alcon Research | 122 | 2010-04-01 | 2012-06-11 |
| Loteprednol and Tobramycin Versus Tobramycin and Dexamethasone, in the Treatment of Blepharokeratoconjunctivitis Loteprednol and tobramycin, Tobramycin and dexamethasone - Conjunctivitis, Keratitis | Phase 3 | Completed | Bausch & Lomb Incorporated | 357 | 2009-10-01 | 2012-02-28 |
| Ketorolac Plus Tobramycin/Dexamethasone Versus Tobramycin/Dexamethasone After Uneventful Phacoemulsification Surgery Drug: Tobramycin 0.3% - Dexamethasone 0.1%, Drug: Tobramycin-Dexamethasone plus Ketorolac tromethamine - Cataract | Not applicable | Completed | Veroia General Hospital | 145 | 2009-10-01 | 2015-04-15 |
| TOBRADEX Ophthalmic Suspension Versus Tobramycin 0.3%/Dexamethasone 0.05% Ophthalmic Suspension Tobramycin 0.3%/Dexamethasone 0.05%, TOBRADEX - Ocular Inflammation Associated With Blepharaconjunctivitis | Phase 3 | Completed | Alcon Research | 221 | 2007-10-01 | 2010-03-02 |
| Tobradex BID Compared to TOBRADEX and TOBREX/Vehicle Tobradex (Antibiotic steroid combination) - Post-surgical Inflammation | Phase 3 | Withdrawn | Alcon Research | 2006-12-01 | 2012-03-06 | |
| A Bioequivalence Study of Tobradex AF Tobramycin 0.3% / Dexamethasone 0.033% ophthalmic suspension, Tobramycin 0.3% / Dexamethasone 0.1% ophthalmic suspension (TOBRADEX) - Cataract | Phase 3 | Completed | Alcon Research | 995 | 2006-04-01 | 2012-03-05 |
| Intraocular Pressure With Loteprednol and Dexamethasone Loteprednol Etabonate 0.5%, Dexamethasone 0.1% - Glaucoma, Open-Angle, Ocular Hypertension | Phase 4 | Completed | Federal University of São Paulo | 35 | 2006-03-01 | 2008-10-28 |
| Ocular Tolerance and Intraocular Pressure (IOP) Effects of Zylet Versus Tobradex Loteprednol etabonate 0.5% and tobramycin 0.3%, Dexamethasone 0.1% and tobramycin 0.3% - Inflammation | Phase 4 | Completed | Bausch & Lomb Incorporated | 310 | 2005-02-01 | 2011-12-08 |
| UARK 98-026 TT II: Multiple Myeloma Evaluating Anti-Angiogenesis With Thalidomide and Post-Transplant Consolidation Chemotherapy Thalidomide, Ara-C, BCNU - Multiple Myeloma | Phase 3 | Completed | University of Arkansas | 668 | 1998-08-01 | 2015-11-23 |
Cataract (3) · Astigmatism (2) · Blepharitis (2) · Myopia (2) · Conjunctivitis (1) · Glaucoma (1) · Glaucoma, Open-Angle (1) · Inflammation (1) · Keratitis (1) · Lacerations (1) · Multiple Myeloma (1) · Neoplasms (1) · Ocular Hypertension (1) · Pain (1) · Pterygium (1)
Alcon Research (4) · Sun Yat-sen University (3) · Bausch & Lomb Incorporated (2) · Azidus Brasil (1) · Federal University of São Paulo (1) · McMaster University (1) · NTC srl (1) · Sutphin Drugs (1) · Umm Al-Qura University (1) · University of Arkansas (1) · Veroia General Hospital (1)
United States (6) · Brazil (2) · China (2) · Canada (1) · Italy (1) · Saudi Arabia (1) · Singapore (1)
Ajai Prakash (1) · Albert Y Wu, M.D., Ph.D. (1) · Bart Barlogie, M.D., Ph.D. (1) · Esther Chu (1) · Francesco Bandello, Prof. (1) · Leonidas E Papazisis, Director (1) · Luciano M Pinto, MD (1) · Michael Brubaker, BSN MPH (1) · Timothy L Comstock, DO (1) · Xingwu Zhong (1) · Xingwu Zhong, MD PhD (1) · Xingwu Zhong, MD, PhD (1)
PMID 16525139, PMID 18577309, PMID 21138337, PMID 22256909, PMID 22689675, PMID 26937680, PMID 27581518, PMID 29338124, PMID 37920592, PMID 40471585, PMID 40501401, PMID 41952147