7 completed, 1 recruiting. 3 Not applicable, 3 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 3 |
| Phase 2 | 3 | Completed 3 |
| Phase 3 | 3 | Completed 2, Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Trial on Bowel Preparation Comparing Mannitol 100g to Plenvu Both in a Same Day Regimen (CLEARWAY) 100g of Mannitol, 1L PEG-Asc - Elective Colonoscopy | Phase 3 | Recruiting | NTC srl | 412 | 2025-09-02 | 2026-03-13 |
| Assessment of the Effects and Tolerability of RD03/2016 for the Treatment of Bacterial Conjunctivitis in Adults RD03/2016 eye drops, Levofloxacin 0.5% eye drops solution (Oftaquix®) - Conjunctivitis, Bacterial | Phase 2 | Completed | NTC srl | 252 | 2021-11-05 | 2024-09-27 |
| Efficacy and Safety of mAnnitol in Bowel Preparation During Elective Colonoscopy and Comparison With Moviprep® Phase II: NTC015 low dose, Phase II: NTC015 medium dose, Phase II: NTC015 high dose - Elective Colonoscopy | Phase 2 / Phase 3 | Completed | NTC srl | 886 | 2020-06-18 | 2025-12-08 |
| Vaginal and Rectal Colonization of Lactobacillus Crispatus NTCVAG04 Following Oral Administration in Patients With History of Vaginitis/Vaginosis BIOVAGINIL - Vaginitis, Vaginosis | Not applicable | Completed | NTC srl | 20 | 2019-11-22 | 2020-12-21 |
| Evaluation Of Aqueous Humor Of Levofloxacin-Dexamethasone Eye Drops And Of Its Components In Patients Undergoing Cataract Surgery Levofloxacin + Dexamethasone, Levofloxacin, Dexamethasone - Cataract | Phase 2 | Completed | NTC srl | 125 | 2018-09-04 | 2020-07-07 |
| Levo-Dexa vs. Tobra+Dexa for Prevention and Treatment of Inflammation and Prevention of Infection in Cataract Surgery Levofloxacin + dexamethasone followed by dexamethasone, Tobramycin + Dexamethasone - Cataract | Phase 3 | Completed | NTC srl | 808 | 2018-09-03 | 2020-08-18 |
| Efficacy and Safety of Lertal® as an add-on to Standard Therapy for Allergic Rhinoconjunctivitis in Pediatrics Lertal® + standard therapy, Placebo + standard therapy - Allergic Rhinoconjunctivitis | Not applicable | Completed | NTC srl | 150 | 2017-09-15 | 2018-11-15 |
| To Compare Blephapad Combo vs Standard Treatment for Eyelid Cleansing in Bilateral Posterior Blepharitis Blephapad Combo, Standard treatment - Bilateral Blepharitis (Disorder) | Not applicable | Completed | NTC srl | 19 | 2017-05-15 | 2019-12-19 |
Cataract (2) · Conjunctivitis, Bacterial (1) · Mucopolysaccharidosis IV (1) · Vaginal Diseases (1) · Vaginitis (1)
Levofloxacin (3) · Dexamethasone (1) · Mannitol (1) · MoviPrep (1) · Ophthalmic Solutions (1) · Standard of Care (1) · Tobramycin, Dexamethasone Drug Combination (1)
Italy (8) · Germany (2) · Russia (2) · Spain (2) · Belgium (1) · France (1) · Poland (1) · Sweden (1)
Francesco Bandello, Prof. (2) · Cristiano Spada, Prof. (1) · Gian Luigi Marseglia, Prof. (1) · Gianpiero Manes, Dr. (1) · Marco Nardi, Prof. (1) · Vincenzo De Leo (1) · Vincenzo Scorcia (1)
PMID 30929188, PMID 31319883, PMID 32285142, PMID 36799346, PMID 40786127
2019 (1)