73 completed, 11 recruiting, 11 unknown, 10 terminated. 116 Phase 3, 27 Phase 2.
Follow Therapeutics: new trials by email Literature Review of Therapeutics trials Research Report on Therapeutics
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Short Course of Intravenous Dexamethasone and Intravenous Immunoglobulin Therapy in Infection-Related Secondary Hemophagocytic Lymphohistiocytosis (isHLH) Intravenous Immunoglobulin (IVIg) therapy, Intravenous Dexamethasone (IVD) therapy, Targeted antimicrobial therapy & standard care - Hemophagocytic Lymphohistiocytosis (HLH), Secondary Hemophagocytic Lymphohistiocytosis | Phase 3 | Not yet recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 116 | 2026-10-15 | 2026-10-06 |
| A 6-Month MDR-END Plus Regimen for Rifampicin-Resistant Tuberculosis MDR-END Plus regimen, Standard-of-care (SoC) treatment - Rifampicin-Resistant Tuberculosis | Phase 3 | Not yet recruiting | Seoul National University Hospital | 294 | 2026-10-01 | 2026-06-30 |
| APEX-STROKE Adaptive Platform Trial for Stroke Early Angong Niuhuang Pill Treatment, Yiqi Huayu Jiedu Mixture, Surgical bundle - Stroke | Phase 3 | Not yet recruiting | Fudan University | 20000 | 2026-09-01 | 2026-08-25 |
| Evaluating Hormone Therapy to Achieve Optimal Doses in Metastatic Prostate Cancer Abiraterone, Apalutamide, Enzalutamide or Darolutamide (ARPI therapy) (per standard of care) therapy - Prostate Cancer, mHSPC | Phase 3 | Recruiting | University College, London | 1500 | 2026-08-28 | 2026-10-16 |
| Implementation of Vancomycin Powder Application in the Emergency Department for Open Fractures Vancomycin (VAN) treatment, Standard Open Fracture Care - Open Fracture | Phase 3 | Not yet recruiting | Atlantic Health System | 100 | 2026-06-10 | 2026-06-22 |
| PROlonged Corticosteroid Treatment or N-ACetylcysteine for Severe Alcoholic Hepatitis N-Acetylcysteine (NAC) Treatment, Prednisolone, Placebo of N-acetylcysteine - Alcoholic Hepatitis | Phase 3 | Recruiting | University Hospital, Lille | 477 | 2026-05-22 | 2026-06-01 |
| PCSK9 Inhibitors in the Treatment of Calcific Aortic Stenosis Treatment with PCSK9 inhibitors, Treatment without PCSK9 inhibitors - Aortic Stenosis, Calcific | Phase 3 | Not yet recruiting | Beijing Anzhen Hospital | 160 | 2026-04-01 | 2026-04-02 |
| A Trial of 2 Disease-Modifying Drugs (Metformin and N-acetylcysteine ) to Promote TB Lung Function Recovery Metformin, N-Acetylcysteine (NAC) Treatment, Standard TB treatment - Tuberculosis | Phase 3 | Not yet recruiting | Open Source Pharma Foundation | 1104 | 2026-01-01 | 2025-08-22 |
| Anticholinergics for Cervical Edema in Labor Treatment with Diphenhydramine, Usual Care - Labor Dystocia | Phase 2 / Phase 3 | Recruiting | The University of Texas Health Science Center, Houston | 200 | 2025-03-25 | 2026-05-06 |
| Phase 3 - Evaluation of Veregen® 10% Ointment as New Herbal Topical Treatment for Actinic Keratosis Topical treatment - Actinic Keratosis of Face and Scalp | Phase 3 | Recruiting | Aresus Pharma GmbH | 280 | 2024-09-04 | 2025-08-22 |
| Nifedipine Extended-Release in Patients With Mild or Moderate Hypertension Treatment with Nifedipine 30 mg Extended-Release (Richmond), Comparator Nifedipine 30 mg Extended-Release - High Blood Pressure (& [Essential Hypertension]) | Phase 3 | Completed | Laboratorios Richmond S.A.C.I.F. | 50 | 2024-07-09 | 2026-08-13 |
| Quetiapine to Reduce Post Concussive Syndrome After Mild Traumatic Brain Injury (mTBI) Quetiapine Fumarate, TAU - Mild Traumatic Brain Injury | Phase 3 | Recruiting | Foundation for Advancing Veterans' Health Research | 146 | 2024-07-09 | 2025-07-11 |
| N-Acetylcysteine as Therapy for Transplantation- Associated Thrombotic Microangiopathy N-Acetylcysteine (NAC) Treatment - Thrombotic Microangiopathy | Phase 2 / Phase 3 | Active not recruiting | The First Affiliated Hospital of Soochow University | 44 | 2024-05-01 | 2025-12-12 |
| Efficacy and Safety Evaluation Study of SCT800 in Previously Untreated Hemophilia A Patients. SCT800 prophylaxis and treatment for bleeding events - Haemophilia A | Phase 3 | Recruiting | Sinocelltech Ltd. | 36 | 2024-04-26 | 2026-02-27 |
| Colposcopy Anxiety and the Role of Pre-procedure Nursing Intervention Pre-colposcopy counseling by a clinical nurse, Treatment as usual: regular call to schedule the appointment without pre-procedure conseilling - Anxiety, Pain | Phase 3 | Completed | Université de Sherbrooke | 140 | 2024-01-08 | 2025-07-29 |
| Efficiency of a Composite Personalised Care on Functional Outcome in Early Psychosis Cognitive training, Personalized neuroprotective strategies : Vitamin B12, folinic acid, Omega 3, NAC, Treatment as usual (TAU) - Psychosis | Phase 3 | Recruiting | Centre Hospitalier St Anne | 500 | 2023-12-15 | 2026-04-20 |
| CMP-MYTHiC Trial and Registry - CardioMyoPathy With MYocarditis THerapy With Colchicine Colchicine, Placebo - Cardiomyopathies, Myocarditis | Phase 3 | Recruiting | Niguarda Hospital | 80 | 2023-11-14 | 2026-04-20 |
| Outcome Study of Conventional Steroids Vs. Steroids Combined with Mycopehnolate in Newly Diagnosed Immune Thrombocytopenia Purpura. Mycophenolate Mofetil (MMF) Treatment - Immune Thrombocytopenia Purpura | Phase 3 | Completed | National Institute of Blood and Marrow Transplant (NIBMT), Pakistan | 118 | 2023-08-18 | 2024-11-06 |
| Tranexamic Acid for The Management of Bleeding Gastrointestinal Angioectasias Tranexamic Acid (TXA) treatment, Placebo - Anemia, Small Bowel Bleeding | Phase 2 / Phase 3 | Completed | Louisiana State University Health Sciences Center in New Orleans | 40 | 2023-08-01 | 2025-08-15 |
| A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain Multimodal Bundle Drugs, Operative Cystoscopy, Behavioral health consultation/therapy - Interstitial Cystitis, Levator Spasm | Phase 3 | Terminated | Jocelyn Fitzgerald | 26 | 2022-12-06 | 2026-04-01 |
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Stress Disorders, Post-Traumatic (7) · Opioid-Related Disorders (6) · Anxiety Disorders (5) · Prostatic Neoplasms (5) · Substance-Related Disorders (5) · Lymphoma, Follicular (4) · Breast Neoplasms (3) · Depression (3) · Depressive Disorder, Major (3) · Fatigue (3) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (3) · Recurrence (3) · Schizophrenia (3) · Stroke (3) · Acquired Immunodeficiency Syndrome (2)
University College, London (3) · Amgen (2) · Assistance Publique - Hôpitaux de Paris (2) · Nagoya City University (2) · Oregon Health and Science University (2) · Pfizer (2) · Resilient Pharmaceuticals (2) · Sanofi (2) · Sun Yat-sen University (2) · The University of Hong Kong (2) · The University of Texas Health Science Center, Houston (2) · Ultragenyx Pharmaceutical Inc (2) · University of Pennsylvania (2) · University of South Florida (2) · AB Biotics, SA (1)
United States (46) · France (19) · Italy (13) · Spain (13) · United Kingdom (13) · Canada (11) · Germany (11) · China (9) · Australia (7) · Belgium (7) · Brazil (7) · Japan (6) · Netherlands (6) · Israel (5) · Colombia (4)
Eric A Storch, Ph.D. (2) · Aaron D Fox, MD, MS (1) · Adrian Raine (1) · Ahmed A. Dobie, Msc. (1) · Ailton Melo, PhD (1) · Akira Yamao (1) · Albert KK Chung, MBBS(HK) (1) · Alvaro A. Martinez, MD, FACR (1) · Amal K Mitra, MD, DrPH (1) · Ananya Choudhury, Professor (1) · Andre Strydom, MD PhD (1)
PMID 40342086, PMID 34752208, PMID 35636689, PMID 36356712, PMID 12377323, PMID 12777656, PMID 12877429, PMID 15001284, PMID 15119583, PMID 15214887, PMID 15302749, PMID 15616839, PMID 16009415, PMID 16211552, PMID 17262225, PMID 17288322, PMID 17466514, PMID 17845167, PMID 17921185, PMID 18228057, PMID 18402714, PMID 18666493, PMID 18673542, PMID 18717178, PMID 18955565, PMID 19411519, PMID 19470315, PMID 19830963, PMID 20005565, PMID 20593911, PMID 20978636, PMID 21075957, PMID 21185685, PMID 21266777, PMID 21457679, PMID 21562038, PMID 21762980, PMID 21967492, PMID 22316363, PMID 22657748, PMID 23357440, PMID 23528439, PMID 23747824, PMID 23795871, PMID 23795877, PMID 23796341, PMID 24004965, PMID 24439950, PMID 24473714, PMID 24733990
2015 (2), 2016 (2), 2019 (2), 2023 (2), 1RC1DA028467-01 (1), 2005 (1), 2014 (1), 2018 (1), 2025 (1), 5RC2DA028864 (1), 5UG1DA040316-05 (1), P01CA015396 (1), P30CA006973 (1), R01CA112631 (1), R01DA018954 (1)