6 completed, 3 not yet recruiting, 1 unknown. 10 Phase 2, 3 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 6, Not yet recruiting 3, Unknown 1 |
| Phase 3 | 3 | Completed 2, Unknown 1 |
| Phase 1 | 2 | Completed 1, Not yet recruiting 1 |
Follow Synbiotics: new trials by email Literature Review of Synbiotics trials Research Report on Synbiotics
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Precision Modulation of Gut Microbiome Enteropathogen Colonization in Critical Illness Synbiotic, Standard of Care (SOC) - Critical Illness | Phase 1 / Phase 2 | Not yet recruiting | University of Calgary | 64 | 2027-01-01 | 2026-09-10 |
| Synbiotic as an Adjuvant Therapy for Dyslipidaemia and Gut Health Synbiotic (LAB12 and SWEOAT® Bran), Oat-based Placebo - Dyslipidemia | Phase 2 | Not yet recruiting | Universiti Teknologi Mara | 190 | 2026-12-02 | 2026-11-05 |
| Effects of Synbiotics on Obesity Placebo, Synbiotics - Obesity | Phase 2 | Not yet recruiting | Leeuwenhoek Laboratories Co. Ltd. | 80 | 2024-10-15 | 2024-10-09 |
| The Efficacy and Safty of FMT in Patients With CID fecal microbiota, Placebo, synbiotics - Insomnia Chronic, Fecal Microbiota Transplantation | Phase 1 / Phase 2 | Completed | Peking University Sixth Hospital | 80 | 2023-10-08 | 2026-02-27 |
| SEPSIS: L. Plantarum Trial Synbiotic, Probiotic, Placebo - Microbial Colonization, Tolerance | Phase 2 | Completed | The Hospital for Sick Children | 519 | 2022-01-07 | 2023-04-13 |
| The Effect of Synbiotics Supplement on Lipid Profile, Liver Enzymes, Inflammatory Factors and Hepatic Fibrosis in Lean and Normal Weight Patients With Nonalcoholic Fatty Liver synbiotic, Placebo - Non Alcoholic Steatohepatitis | Phase 2 / Phase 3 | Unknown | National Nutrition and Food Technology Institute | 42 | 2014-08-01 | 2015-08-20 |
| Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim2) Maltodextrin, Synbiotic, Sevelamer - Insulin Sensitivity | Phase 2 | Completed | The University of Texas Health Science Center at San Antonio | 69 | 2014-04-10 | 2020-09-11 |
| Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim 1) Sevelamer, Synbiotic, Maltodextrin - Insulin Sensitivity | Phase 2 | Completed | The University of Texas Health Science Center at San Antonio | 20 | 2014-04-02 | 2021-10-15 |
| Effects of Synbiotic Supplementation in Metabolic Syndrome Synbiotic, Placebo - Metabolic Syndrome | Phase 2 / Phase 3 | Completed | National Nutrition and Food Technology Institute | 38 | 2012-04-01 | 2013-12-11 |
| The Effects of Synbiotics Supplement on Biochemical Factors and Hepatic Fibrosis in Patients With Nonalcoholic Steatohepatitis synbiotic, placebo - Non Alcoholic Steatohepatitis | Phase 2 / Phase 3 | Completed | National Nutrition and Food Technology Institute | 54 | 2012-03-01 | 2013-02-15 |
Insulin Resistance (2) · Non-alcoholic Fatty Liver Disease (2) · Anxiety Disorders (1) · Cognitive Dysfunction (1) · Communicable Diseases (1) · Critical Illness (1) · Cross Infection (1) · Depression (1) · Dyslipidemias (1) · Metabolic Syndrome (1) · Obesity (1) · Sleep Initiation and Maintenance Disorders (1) · Sleep Wake Disorders (1)
National Nutrition and Food Technology Institute (3) · The University of Texas Health Science Center at San Antonio (2) · Leeuwenhoek Laboratories Co. Ltd. (1) · Peking University Sixth Hospital (1) · The Hospital for Sick Children (1) · Universiti Teknologi Mara (1) · University of Calgary (1)
United States (2) · Bangladesh (1) · Canada (1) · China (1) · Iran (1) · Malaysia (1)
Nicolas Musi, MD. (2) · Azita Hekmatdoost, MD, PhD (1) · Daniel Roth, MD, PhD (1) · Kalavathy Ramasamy, Professor Dr (1) · Lim Siong Meng, Professor Dr (1)
PMID 24401715, PMID 39992135, PMID 42026772, PMID 42066676, PMID 42141362