18 completed, 2 recruiting, 2 terminated, 2 unknown. 26 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 26 | Completed 18, Recruiting 2, Terminated 2, Unknown 2, Withdrawn 2 |
| Phase 2 | 4 | Unknown 2, Completed 1, Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Assess the Safety and Efficacy of ZX-7101A for Oral Suspension in Chinese Pediatric Participants 2 to 11 Years of Age With Influenza ZX-7101A for oral suspension, Oseltamivir phosphate for oral suspension - Respiratory Viral Infection | Phase 3 | Completed | Nanjing Zenshine Pharmaceuticals | 169 | 2025-10-13 | 2026-04-16 |
| Lumason® Infusion vs. Bolus Administrations Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON], Lumason - Heart Diseases | Phase 3 | Recruiting | Bracco Diagnostics, Inc | 106 | 2024-07-10 | 2026-10-20 |
| Trial Evaluating the Efficacy and Safety of Patiromer in Chinese Subjects Patiromer Powder for Oral Suspension (Part A), Placebo (Part B), Patiromer Powder for Orals Suspension (Part B) - Hyperkalemia, Renal Insufficiency, Chronic | Phase 3 | Completed | Vifor Fresenius Medical Care Renal Pharma | 262 | 2022-02-10 | 2026-04-13 |
| Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression Depo-Medrol 40Mg/Ml Suspension for Injection, Placebo - Opioid Use, Lumbar Spinal Stenosis | Phase 3 | Recruiting | Hospital for Special Surgery, New York | 150 | 2021-11-05 | 2026-04-28 |
| Acute Bronchodilator Effects of Ipratropium/Levosalbutamol 20/50 mcg Fixed Dose Combination vs Salbutamol 100 mcg Inhaler Plus Ipratropium 20 mcg Inhalation Aerosol Free Combination in Patients With Stable COPD Ipratropium/Levosalbutamol 20/50 mcg Fixed Dose Combination (2 inhalations) via pMDI, Salbutamol 100 mcg Inhaler (2 inhalations) + Ipratropium 20 mcg Inhalation Aerosol (2 inhalations) Free Combination via MDI - Chronic Obstructive Pulmonary Disease | Phase 3 | Withdrawn | Neutec Ar-Ge San ve Tic A.Ş | 2021-09-03 | 2021-09-13 | |
| A New Posaconazole Dosing Regimen for Paediatric Patients With Cystic Fibrosis and Aspergillus Infection Posaconazole 100 MG [Noxafil], Posaconazole 40 MG/ML - Cystic Fibrosis, Aspergillosis | Phase 2 / Phase 3 | Unknown | Bambino Gesù Hospital and Research Institute | 135 | 2021-04-22 | 2021-07-19 |
| Phase 3, Randomized, Double Blinded, Active Controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL Admixed With Bupi vs. Bupi Only Administered as Combined Sciatic and Adductor Canal Nerve Block for Postsurgical Analgesia in Lower Extremity Surgeries EXPAREL 13.3Mg/mL Suspension for Injection, Bupivacaine Hydrochloride - Bunion, Metatarsophalangeal Fusion | Phase 3 | Withdrawn | Pacira Pharmaceuticals, Inc | 2020-06-15 | 2020-08-13 | |
| Use of Topical NSAID to Reduce Pain in Oral Lichen Planus and Oral Lichenoid Lesions. Ibuprofen suspension 5mg/100ml, Placebos - Oral Lichen Planus, Oral Lichenoid Mucositis | Phase 2 / Phase 3 | Completed | University of Washington | 23 | 2018-04-29 | 2020-05-08 |
| Evaluation of the Benefit of Antiviral Treatment With Valganciclovir on Congenital CMV Infection-related Deafness on Hearing and Balance Valganciclovir - Congenital Cytomegalovirus (CMV) | Phase 2 / Phase 3 | Terminated | Assistance Publique - Hôpitaux de Paris | 1 | 2017-07-11 | 2019-11-18 |
| Phase 3 Trial to Assess the Safety and Efficacy of Natroba for the Treatment of Scabies spinosad topical suspension, 0.9%, Placebo - Scabies | Phase 3 | Completed | ParaPRO LLC | 280 | 2017-05-10 | 2021-05-21 |
| Phase 3 Trial to Assess the Safety and Efficacy of Natroba for the Treatment of Scabies spinosad topical suspension, 0.9%, Placebo - Scabies | Phase 3 | Completed | ParaPRO LLC | 291 | 2017-05-02 | 2021-05-19 |
| Combination Treatment of 5% Natamycin and 1% Voriconazole in Fungal Keratitis Group 1 Natamycin 5% Suspension + voriconazole 1% eye drops; Group 2 Natamycin 5% Suspension + Vehicle eye drops - Infection, Fungal | Phase 2 / Phase 3 | Unknown | L.V. Prasad Eye Institute | 55 | 2017-01-01 | 2017-07-26 |
| Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT) Brinzolamide 10 mg/mL / Brimonidine 2 mg/mL fixed combination eye drops, suspension, Brinzolamide 10 mg/mL eye drops, suspension, Brimonidine 2 mg/mL eye drops, solution - Open-Angle Glaucoma, Ocular Hypertension | Phase 3 | Completed | Alcon Research | 493 | 2015-04-14 | 2018-07-02 |
| A Two-Part, Single-Blind, Phase 3 Study Evaluating the Efficacy and Safety of Patiromer for the Treatment of Hyperkalemia (OPAL) Patiromer, Placebo - Chronic Kidney Disease (CKD), Hyperkalemia (HK) | Phase 3 | Completed | Relypsa, Inc. | 243 | 2013-02-01 | 2021-06-03 |
| beCLomethasone Efficacy in Acute Rhinosinusitis - CLEAR Study beclomethasone dipropionate 800 mcg/2 ml suspension for nebulization,one administration b.i.d. for 14 days, placebo 2 ml suspension for nebulization, one administration b.i.d. for 14 days - Acute Rhinosinusitis | Phase 3 | Completed | Chiesi Farmaceutici S.p.A. | 166 | 2013-01-01 | 2017-03-29 |
| A Study of the Safety and Efficacy of Aprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in Pediatric Participants (MK-0869-208) Aprepitant 125 mg, Aprepitant 80 mg, Aprepitant powder for suspension (PFS) - Chemotherapy Induced Nausea and Vomiting | Phase 3 | Completed | Merck Sharp & Dohme LLC | 307 | 2011-09-13 | 2018-09-25 |
| Efficacy Study of Polyunsaturated Fatty Acids in Children and Adolescents With Attention Deficit/ Hyperactivity Disorder ω-3 fatty acids suspension, placebo suspension - ADHD | Phase 3 | Terminated | Johannes Gutenberg University Mainz | 284 | 2011-03-08 | 2017-09-20 |
| LEO 80185 in the Treatment of Psoriasis Vulgaris on the Non-scalp Regions of the Body (Trunk and/or Limbs) Calcipotriol plus betamethasone, Betamethasone-17,21-dipropionate, Calcipotriene - Psoriasis Vulgaris | Phase 3 | Completed | LEO Pharma | 1152 | 2010-09-01 | 2025-03-10 |
| Safety and Efficacy Study of NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects 6 Months or Older With Head Lice Spinosad, Permethrin 1% - Pediculosis | Phase 3 | Completed | ParaPRO LLC | 558 | 2007-09-01 | 2012-10-11 |
| Safety and Efficacy Study of NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects 6 Months or Older With Head Lice Spinosad, Permethrin 1% - Pediculus Capitis Infestation | Phase 3 | Completed | ParaPRO LLC | 480 | 2007-09-01 | 2012-10-11 |
Showing 20 of 26. Sign in to see all of them.
Glaucoma, Open-Angle (3) · Ocular Hypertension (3) · Hyperkalemia (2) · Renal Insufficiency, Chronic (2) · Scabies (2) · Acromegaly (1) · Aspergillosis (1) · Attention Deficit Disorder with Hyperactivity (1) · Back Pain (1) · Breast Feeding (1) · Bunion (1) · Cataract (1) · Cystic Fibrosis (1) · Cytomegalovirus Infections (1) · HIV Infections (1)
Alcon Research (4) · ParaPRO LLC (4) · Assistance Publique - Hôpitaux de Paris (1) · Bambino Gesù Hospital and Research Institute (1) · Bracco Diagnostics, Inc (1) · Centers for Disease Control and Prevention (1) · Chiesi Farmaceutici S.p.A. (1) · Gilead Sciences (1) · Hospital for Special Surgery, New York (1) · Johannes Gutenberg University Mainz (1) · L.V. Prasad Eye Institute (1) · LEO Pharma (1) · Merck Sharp & Dohme LLC (1) · Nanjing Zenshine Pharmaceuticals (1) · Neutec Ar-Ge San ve Tic A.Ş (1)
United States (11) · Italy (4) · France (3) · China (2) · Czechia (2) · Germany (2) · Croatia (1) · Denmark (1) · Georgia (1) · Greece (1) · Hungary (1) · India (1) · Ireland (1) · Malawi (1) · Netherlands (1)
Bill Miller, MD (2) · Kerry W Mettert, MBA (2) · Adilia Warris, Prof (1) · Alan Menter, MD (1) · Alicia Bucko, MD (1) · Amy M Morris, MD (1) · Andrew King, MD (1) · Brent M Boyce, MD (1) · Catherine Hren, MD (1) · Charles P Hudson, MD (1) · Charles van der Horst, MD (1) · Chernila Selbert Alan, MD (1) · Dale Martin, MD (1)
PMID 15232472, PMID 18538406, PMID 19365194, PMID 19668532, PMID 20554982, PMID 21212103, PMID 22541418, PMID 22649265, PMID 23468553, PMID 23700341, PMID 24381222, PMID 24500152, PMID 25723140, PMID 25770814, PMID 26156797, PMID 29893452, PMID 32588430, PMID 41365527
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