10 completed, 7 unknown, 4 terminated, 1 not yet recruiting. 23 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 23 | Completed 10, Unknown 7, Terminated 4, Not yet recruiting 1, Recruiting 1 |
Follow Sunitinib: new trials by email Literature Review of Sunitinib trials Research Report on Sunitinib
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multimodal Recurrence Scoring System for Stratifying Stage III Clear Cell Renal Cell Carcinoma of Receiving Adjuvant Treatment Sunitinib - Renal Cell Carcinoma | Not applicable | Not yet recruiting | First Affiliated Hospital, Sun Yat-Sen University | 488 | 2023-10-01 | 2023-09-13 |
| Apatinib Mesylate Versus Standard Second-line TKI in the Treatment of Advanced GIST Apatinib Mesylate, Sunitinib, Imatinib dosage, Dasatinib, Reveratinib - Gastrointestinal Stromal Tumors | Not applicable | Recruiting | Xiangya Hospital of Central South University | 258 | 2023-02-01 | 2023-03-02 |
| Application Circulating Tumor DNA Dynamic Monitoring in Clinical Treatment of Metastatic Renal Cell Carcinoma sunitinib or pazopanib, PD-1 inhibitor combined with axitinib - Metastatic Renal Cell Carcinoma | Not applicable | Unknown | RenJi Hospital | 500 | 2022-08-01 | 2023-04-18 |
| Role of Surgery in Patients With Focally Progressive Gastrointestinal Stromal Tumors (GISTs) After Imatinib Treatment surgery, Imatinib 400 MG, Imatinib escalation - Gastrointestinal Stromal Tumors, Surgery | Not applicable | Unknown | Shanghai Zhongshan Hospital | 92 | 2019-07-01 | 2019-03-05 |
| Evaluation of a Promising New Combination of Protein Kinase Inhibitors on Organotypic Cultures of Human Renal Tumors CK2 and ATM inhibitors serine/ threonin Kinase combination, Sunitinib, Pazopanib - Kidney Cancer | Not applicable | Unknown | University Hospital, Grenoble | 100 | 2017-10-16 | 2020-01-18 |
| A CpG-methylation-based Assay for Stratifying Stage III Clear Cell Renal Cell Carcinoma of Receiving Adjuvant Treatment sunitinib - Renal Neoplasms, Targeted Molecular Therapy | Not applicable | Unknown | First Affiliated Hospital, Sun Yat-Sen University | 300 | 2016-07-01 | 2016-02-25 |
| Single-arm Study to Evaluate the Safety and Efficacy of Sunitinib, in Subjects With RET Fusion Positive or FGFR2 Amplification, Refractory Solid Tumors sunitinib - Refractory Solid Tumors | Not applicable | Completed | Samsung Medical Center | 1 | 2016-03-23 | 2022-06-15 |
| HGG-TCP (High Grade Glioma - Tumor Concentrations of Protein Kinase Inhibitors) Sunitinib, vandetanib, Erlotinib - Cancer, High-grade Glioma | Not applicable | Unknown | Amsterdam UMC, location VUmc | 15 | 2014-11-01 | 2020-10-08 |
| Molecular Determinants for Therapy Response on Renal Cell Carcinoma Sunitinib, Pazopanib, Bevacizumab, Everolimus... - Renal Cell Carcinoma | Not applicable | Unknown | Heidelberg University | 4 | 2014-05-01 | 2014-08-04 |
| A Pilot Study of Genomic Sequencing Guided Individualized Therapy in Gastrointestinal Cancers, GITIC Study Erlotinib or Gefitinib, Everolimus, Imatinib - Gastrointestinal Cancers | Not applicable | Unknown | Sun Yat-sen University | 50 | 2013-12-01 | 2016-08-30 |
| Sunitinib Malate Related Fatigue in Patients With Metastatic Kidney Cancer transcranial magnetic stimulation, electromyography, survey administration - Fatigue, Recurrent Renal Cell Cancer | Not applicable | Terminated | Case Comprehensive Cancer Center | 13 | 2012-09-01 | 2018-12-06 |
| PET/CT Assessment of Tumor Perfusion in Patients With Renal Cell Carcinoma 150-Water, 62Cu-ethylglyoxal bis, Positron Emission Tomography - Renal Cell Carcinoma | Not applicable | Terminated | Indiana University | 14 | 2011-10-01 | 2019-03-05 |
| Determination of Intratumoral Concentrations of Kinase Inhibitors in Patients With Advanced Solid Malignancies. Sunitinib, Sorafenib, Erlotinib - Cancer, Advanced Solid Tumors | Not applicable | Completed | Amsterdam UMC, location VUmc | 43 | 2011-08-01 | 2021-04-15 |
| Targeted Therapy Selection Based on Tumor Tissue Kinase Activity Profiles for Patients With Advanced Solid Malignancies, an Exploratory Study desatinib or sunitinib or erlotinib or everolimus or lapatinib or sorafenib - Advanced Solid Tumors, Inoperable | Not applicable | Terminated | Amsterdam UMC, location VUmc | 45 | 2010-08-01 | 2020-11-20 |
| Evaluation of Patients With Bulky GIST Using Sunitinib Sunitinib, Surgery - Tumor | Not applicable | Terminated | University of Alabama at Birmingham | 5 | 2009-10-01 | 2016-09-22 |
| Sunitinib Malate in Treating Patients With Kidney Cancer sunitinib malate, laboratory biomarker analysis, pharmacological study - Kidney Cancer | Not applicable | Completed | Centre Antoine Lacassagne | 60 | 2009-02-01 | 2016-11-10 |
| Exploratory Study of Sunitinib Malate as a Component of Neoadjuvant Therapy for Breast Cancer sunitinib alone, sunitinib plus paclitaxel, doxorubicin and cyclophosphamide - Breast Cancer | Not applicable | Completed | Indiana University | 23 | 2008-04-01 | 2023-05-23 |
| Evaluating Sunitinib Therapy in Renal Cell Carcinoma Using F-18 FDG PET/CT and DCE MRI FDG PET CT, DCE MRI, F-18 Fluoro-deoxi-glucose - Kidney Neoplasms, Carcinoma, Renal Cell | Not applicable | Completed | Stanford University | 17 | 2007-10-01 | 2017-06-14 |
| Sunitinib and Surgery in Treating Patients With Localized or Metastatic Kidney Cancer sunitinib malate, neoadjuvant therapy, therapeutic conventional surgery - Kidney Cancer | Not applicable | Completed | Roswell Park Cancer Institute | 20 | 2007-08-01 | 2015-02-06 |
| A Continuation Study Using Sunitinib Malate For Patients Leaving Treatment On A Previous Sunitinib Study. sunitinib - Metastatic Breast Cancer, Advanced Breast Cancer | Not applicable | Completed | Pfizer | 223 | 2007-07-01 | 2019-06-27 |
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Carcinoma, Renal Cell (10) · Kidney Neoplasms (5) · Gastrointestinal Stromal Tumors (4) · Neoplasms (4) · Breast Neoplasms (2) · Adenoma, Islet Cell (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1) · Fatigue (1) · Gastrointestinal Neoplasms (1) · Glioma (1) · Neoplasm Metastasis (1) · Somatostatinoma (1) · Thyroid Neoplasms (1)
Amsterdam UMC, location VUmc (3) · Pfizer (3) · First Affiliated Hospital, Sun Yat-Sen University (2) · Indiana University (2) · Case Comprehensive Cancer Center (1) · Centre Antoine Lacassagne (1) · Heidelberg University (1) · King Faisal Specialist Hospital & Research Center (1) · RenJi Hospital (1) · Roswell Park Cancer Institute (1) · Samsung Medical Center (1) · Shanghai Zhongshan Hospital (1) · Stanford University (1) · Sun Yat-sen University (1) · University Hospital, Grenoble (1)
United States (9) · France (5) · Netherlands (4) · Canada (3) · China (3) · Germany (3) · United Kingdom (3) · Australia (2) · Italy (2) · Singapore (2) · South Korea (2) · Spain (2) · Argentina (1) · Belgium (1) · Brazil (1)
Brian Rini, MD (1) · Dr Andrew Quon (1) · Henk Verheul, M.D., PhD (1) · James A. Posey, M.D. (1) · James Fletcher, M.D. (1) · Jean Marc Ferrero, MD (1) · Jun-Hang Luo, MD (1) · Kathy Miller, MD (1) · Sascha Pahernil, PD Dr. (1) · Shouki Bazarbashi, MD (1) · Theodore Logan, M.D. (1) · Willie Underwood, MD (1) · Yanghong Deng, PhD (1)
PMID 29563634, PMID 30018133, PMID 35165100, PMID 36810959
P30CA016056 (1)