8 completed, 3 unknown, 2 terminated, 2 withdrawn. 15 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 15 | Completed 8, Unknown 3, Terminated 2, Withdrawn 2 |
| Phase 3 | 3 | Unknown 2, Withdrawn 1 |
Follow Sterile water: new trials by email Literature Review of Sterile water trials Research Report on Sterile water
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Antiviral Efficacy and Acceptability of Mouth Rinses for Inactivation of COVID-19 Water, Peroxyl, Periogard - COVID19, Coronavirus Infection | Phase 2 | Terminated | University of North Carolina, Chapel Hill | 2 | 2021-03-26 | 2022-02-16 |
| Enteral Fish Oil is Superior to Ursodeoxycholic Acid (UDCA) and Placebo for the Treatment of Cholestasis in Infants Enteral fish oil, Ursodeoxycholic Acid, Placebo - Cholestasis, Liver Disease | Phase 2 | Withdrawn | The University of Texas Health Science Center at San Antonio | 2016-06-01 | 2016-06-21 | |
| Safety and Efficacy Study of TVGV-1 Vaccine to Treat HPV Induced Cervical HSIL TVGV-1, GPI-0100, Placebo - Human Papillomavirus, High-Grade Squamous Intraepithelial Lesions | Phase 2 | Unknown | THEVAX Genetics Vaccine | 10 | 2015-11-01 | 2017-10-25 |
| Topical Use of Vancomycin in Reducing Sternal Wound Infection in Cardiac Surgery (SWI Trial) Vancomycin, No Vancomycin - INFECTION | Phase 2 | Terminated | University of Alberta | 1037 | 2015-03-01 | 2022-11-03 |
| Magnesium Sulphate for Severe Hand, Foot and Mouth Disease in Vietnam Magnesium Sulphate, Sterile water - Hand, Foot and Mouth Disease | Phase 2 | Completed | Oxford University Clinical Research Unit, Vietnam | 26 | 2014-04-21 | 2017-03-07 |
| Prevention of Nosocomial Infections in Critically Ill Patients With Lactoferrin: The PREVAIL Study Lactoferrin, Placebo - Critically Ill | Phase 2 | Completed | Queen's University | 214 | 2013-11-01 | 2017-02-20 |
| Chlorhexidine Skin Application for Prevention of Infection in Infants Weighing <1500 g at Birth 0.25% chlorhexidine, sterile water - Neonatal Sepsis, Neonatal Mortality Rate | Phase 2 / Phase 3 | Withdrawn | All India Institute of Medical Sciences | 2012-11-01 | 2016-07-18 | |
| Anakinra in Hidradenitis Suppurativa Water for injection, Anakinra - Hidradenitis Suppurativa | Phase 2 | Completed | University of Athens | 20 | 2012-03-01 | 2015-05-27 |
| Effect of a Commercial Cosmetic Mouth Rinse on Plaque Re-growth 0.12% chlorhexidine mouthrinse, Cosmetic mouthrinse, Sterile water - Healthy Subjects | Phase 2 | Completed | GlaxoSmithKline | 23 | 2010-04-01 | 2013-09-09 |
| Efficacy of Potassium Nitrate Solution in Reducing Dentinal Hypersensitivity 5% Potassium nitrate, 2.5% Potassium nitrate, Sterile water - Dentine Hypersensitivity | Phase 2 | Completed | GlaxoSmithKline | 32 | 2009-09-01 | 2015-01-26 |
| Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental Erosion Sodium fluoride, Sodium monoflurophosphate, Sterile water - Tooth Erosion | Phase 2 | Completed | GlaxoSmithKline | 36 | 2009-08-01 | 2015-01-01 |
| Immunogenicity Study of Vacc-4x Versus Placebo in Patients Infected With HIV Vacc-4x, Sterile water - HIV I Infection | Phase 2 | Completed | Bionor Immuno AS | 137 | 2008-08-01 | 2017-02-23 |
| Montelukast With Status Asthmaticus, Ages 2-5 Montelukast, Sterile water - Status Asthmaticus, Asthma | Phase 2 / Phase 3 | Unknown | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 52 | 2006-12-01 | 2008-12-16 |
| Montelukast With Status Asthmaticus, Ages 6-18 Montelukast, sterile water - Status Asthmaticus, Asthma | Phase 2 / Phase 3 | Unknown | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 52 | 2006-12-01 | 2008-12-16 |
| Nasogastric Tube in Premature Babies - Pain and Treatment Sucrose, Pacifier, sterile water - Infant, Premature | Phase 2 | Completed | Norwegian University of Science and Technology | 24 | 2005-01-01 | 2015-04-08 |
Asthma (2) · Status Asthmaticus (2) · COVID-19 (1) · Cholestasis (1) · Coronavirus Infections (1) · Critical Illness (1) · Dental Plaque (1) · Dentin Sensitivity (1) · Hand, Foot and Mouth Disease (1) · Hidradenitis Suppurativa (1) · Infections (1) · Liver Diseases (1) · Neonatal Sepsis (1) · Pain (1) · Premature Birth (1)
GlaxoSmithKline (3) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2) · All India Institute of Medical Sciences (1) · Bionor Immuno AS (1) · Norwegian University of Science and Technology (1) · Oxford University Clinical Research Unit, Vietnam (1) · Queen's University (1) · THEVAX Genetics Vaccine (1) · The University of Texas Health Science Center at San Antonio (1) · University of Alberta (1) · University of Athens (1) · University of North Carolina, Chapel Hill (1)
United States (9) · Canada (1) · Germany (1) · Greece (1) · India (1) · Italy (1) · Norway (1) · Spain (1) · United Kingdom (1) · Vietnam (1)
Abbas Khani-Hanjani, MD (1) · Bridget Wills, MD (1) · Cynthia Blanco, M.D. (1) · Dimitrios Rigopoulos, MD, PhD (1) · Eirik Skogvoll, MD, PhD (1) · Evangelos J Giamarellos-Bourboulis, MD, PhD (1) · Frank L Douglas, PhD, MD (1) · Jeffrey Blumer, MD (1) · Jeffrey L. Blumer, M.D., Ph.D. (1) · John G Muscedere, MD (1) · Richard Pollard, MD (1) · Vinod K Paul, MD, PhD (1)
PMID 21536607, PMID 24525316, PMID 26579854, PMID 26896318, PMID 31438878